ASCENDIS PHARMA A/S
SPONSORED ADR · CUSIP 04351P101 · ISIN US04351P1012
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.2m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $103.29. Options: 14 managers hold calls ($224.7m notional), 11 hold puts ($20.5m).
Biggest calls
| Deep Track Capital, LP | — | $103.3m1.0m shares |
| Caption Management, LLC | — | $66.9m648.0k shares |
| CITADEL ADVISORS LLC | — | $17.0m164.3k shares |
| JANE STREET GROUP, LLC | — | $16.5m159.9k shares |
| GOLDMAN SACHS GROUP INC | — | $7.7m75.0k shares |
| GROUP ONE TRADING LLC | — | $4.4m42.2k shares |
| MILLENNIUM MANAGEMENT LLC | — | $3.7m36.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $3.0m29.0k shares |
| SIMPLEX TRADING, LLC | — | $1.3m12.9k shares |
| Walleye Capital LLC | — | $341.0k3.3k shares |
Biggest puts
| CLEAR STREET LLC | — | $9.3m90.0k shares |
| WOLVERINE ASSET MANAGEMENT LLC | — | $4.3m41.2k shares |
| Caption Management, LLC | — | $2.3m22.0k shares |
| JANE STREET GROUP, LLC | — | $1.8m17.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $1.2m11.2k shares |
| GROUP ONE TRADING LLC | — | $774.0k7.5k shares |
| CITADEL ADVISORS LLC | — | $774.0k7.5k shares |
| Walleye Capital LLC | — | $134.0k1.3k shares |
| Walleye Trading LLC | — | $41.0k400 shares |
| Cutler Group LLC / CA | — | $4.0k3.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| T. Rowe Price Investment Management, Inc. 13G · institution +0.6 pts · filed 2026-05-07 | 10.5% |
| WESTFIELD CAPITAL MANAGEMENT CO LP 13G · institution -0.7 pts · filed 2026-02-11 | 8.5% |
| FMR LLC 13G · institution filed 2025-05-12 | 8.0% |
| JANUS HENDERSON GROUP PLC 13G · institution -1.8 pts · filed 2026-05-15 | 6.0% |
| Artisan Partners Limited Partnership 13G · institution filed 2026-02-03 | 5.2% |
Fell to 5% or below in the last year: Capital International Investors (3.2%, 2026-05-14)
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| JANUS HENDERSON GROUP PLC 0.30% of their portfolio | 7.7m $792.4m | — |
| RA CAPITAL MANAGEMENT, L.P. 16.67% of their portfolio | 7.6m $781.5m | — |
| Artisan Partners Limited Partnership 1.30% of their portfolio | 7.1m $738.3m | — |
| FMR LLC 0.06% of their portfolio | 5.3m $545.1m | — |
| BAKER BROS. ADVISORS LP 3.28% of their portfolio | 4.9m $501.1m | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.07% of their portfolio | 3.9m $400.1m | — |
| WELLINGTON MANAGEMENT GROUP LLP 0.08% of their portfolio | 3.7m $379.2m | — |
| WESTFIELD CAPITAL MANAGEMENT CO LP 2.39% of their portfolio | 2.9m $300.6m | — |
| GOLDMAN SACHS GROUP INC 0.09% of their portfolio | 2.9m $295.2m | — |
| Avoro Capital Advisors LLC 5.44% of their portfolio | 2.9m $294.3m | — |
| T. Rowe Price Investment Management, Inc. 0.17% of their portfolio | 2.0m $209.8m | — |
| Capital International Investors 0.04% of their portfolio | 1.3m $136.2m | — |
| EVENTIDE ASSET MANAGEMENT, LLC 2.44% of their portfolio | 1.2m $123.8m | — |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.05% of their portfolio | 1.2m $122.3m | — |
| FRANKLIN RESOURCES INC 0.06% of their portfolio | 1.2m $119.2m | — |
| Spyglass Capital Management LLC 6.94% of their portfolio | 949.9k $98.1m | — |
| Deep Track Capital, LP 4.08% of their portfolio | 800.0k $82.6m | — |
| PUTNAM INVESTMENTS LLC 0.15% of their portfolio | 788.1k $81.4m | — |
| ALLIANCEBERNSTEIN L.P. 0.03% of their portfolio | 639.9k $66.1m | — |
| TimesSquare Capital Management, LLC 0.92% of their portfolio | 639.7k $66.1m | — |
| BROWN ADVISORY INC 0.13% of their portfolio | 638.0k $65.9m | — |
| Invesco Ltd. 0.02% of their portfolio | 600.0k $62.0m | — |
| Sofinnova Investments, Inc. 3.28% of their portfolio | 499.8k $51.6m | — |
| Paradigm Biocapital Advisors LP 7.23% of their portfolio | 497.3k $51.4m | — |
| SEI INVESTMENTS CO 0.11% of their portfolio | 473.5k $48.9m | — |
| Rock Springs Capital Management LP 1.13% of their portfolio | 425.5k $43.9m | — |
| Point72 Asset Management, L.P. 0.17% of their portfolio | 384.2k $39.7m | — |
| BlackRock Inc. 0.00% of their portfolio | 373.6k $38.6m | — |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 366.1k $37.8m | — |
| AMERICAN CENTURY COMPANIES INC 0.03% of their portfolio | 342.6k $35.4m | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.04% of their portfolio | 278.1k $28.7m | — |
| Bank of New York Mellon Corp 0.01% of their portfolio | 261.4k $27.0m | — |
| MARSHALL WACE, LLP 0.07% of their portfolio | 258.9k $26.7m | — |
| Allspring Global Investments Holdings, LLC 0.05% of their portfolio | 255.9k $26.4m | — |
| Logos Global Management LP 3.18% of their portfolio | 250.0k $25.8m | — |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.06% of their portfolio | 230.0k $23.8m | — |
| ARS Investment Partners, LLC 3.23% of their portfolio | 227.4k $23.5m | — |
| Woodline Partners LP 0.32% of their portfolio | 211.4k $21.8m | — |
| Candriam S.C.A. 0.15% of their portfolio | 206.4k $21.3m | — |
| MORGAN STANLEY 0.00% of their portfolio | 171.5k $17.7m | — |
| Vivo Capital, LLC 1.66% of their portfolio | 146.0k $15.1m | — |
| Q Global Advisors, LLC 11.49% of their portfolio | 145.2k $16.7m | — |
| Nicholas Investment Partners, LP 1.32% of their portfolio | 137.6k $14.2m | — |
| RICE HALL JAMES & ASSOCIATES, LLC 0.82% of their portfolio | 136.4k $14.1m | — |
| DAFNA Capital Management LLC 3.77% of their portfolio | 135.7k $14.0m | — |
| Foresite Capital Management III, LLC 36.44% of their portfolio | 133.7k $13.8m | — |
| TD Asset Management Inc 0.02% of their portfolio | 131.6k $13.5m | — |
| CIBC Asset Management Inc 0.06% of their portfolio | 129.1k $13.3m | — |
| Finepoint Capital LP 4.19% of their portfolio | 123.4k $12.7m | — |
| Driehaus Capital Management LLC 0.19% of their portfolio | 123.3k $12.7m | — |
| Thrivent Financial for Lutherans 0.03% of their portfolio | 122.9k $12.7m | — |
| COMERICA BANK 0.10% of their portfolio | 112.6k $12.0m | — |
| Affinity Asset Advisors, LLC 4.76% of their portfolio | 100.0k $10.3m | — |
| Ghost Tree Capital, LLC 4.01% of their portfolio | 95.0k $9.8m | — |
| D. E. Shaw & Co., Inc. 0.02% of their portfolio | 91.8k $9.5m | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 91.1k $9.4m | — |
| CLEAR STREET LLC 0.93% of their portfolio | 90.2k $9.3m | — |
| BAILLIE GIFFORD & CO 0.01% of their portfolio | 88.5k $9.1m | — |
| Octagon Capital Advisors LP 1.49% of their portfolio | 83.5k $8.6m | — |
| WESTPAC BANKING CORP 0.13% of their portfolio | 81.6k $8.4m | — |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 71.3k $7.4m | — |
| Boxer Capital, LLC 0.41% of their portfolio | 70.0k $7.2m | — |
| Tekla Capital Management LLC 0.29% of their portfolio | 67.8k $7.0m | — |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 66.2k $6.8m | — |
| TANG CAPITAL MANAGEMENT LLC 0.84% of their portfolio | 66.1k $6.8m | — |
| Sessa Capital IM, L.P. 0.43% of their portfolio | 58.5k $6.0m | — |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio | 58.1k $6.0m | — |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 54.5k $5.6m | — |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 53.9k $5.6m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 51.2k $5.3m | — |
| BERYLSON CAPITAL PARTNERS, LLC 8.70% of their portfolio | 51.0k $5.3m | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 50.6k $5.2m | — |
| Cormorant Asset Management, LP 0.36% of their portfolio | 50.0k $5.2m | — |
| Alberta Investment Management Corp 0.04% of their portfolio | 47.3k $4.9m | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 45.5k $4.7m | — |
| Brookfield Corp /ON/ 0.02% of their portfolio | 45.1k $4.7m | — |
| TUDOR INVESTMENT CORP ET AL 0.08% of their portfolio | 31.9k $3.3m | — |
| ALPS ADVISORS INC 0.03% of their portfolio | 30.4k $3.1m | — |
| Resolute Capital Asset Partners LLC 2.78% of their portfolio | 30.0k $3.1m | — |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 0.97% of their portfolio | 29.4k $3.0m | — |
| Evolutionary Tree Capital Management, LLC 2.89% of their portfolio | 29.1k $3.0m | — |
| EcoR1 Capital, LLC 0.08% of their portfolio | 27.2k $2.8m | — |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 26.5k $2.7m | — |
| Henry James International Management Inc. 1.50% of their portfolio | 26.0k $2.7m | — |
| Matisse Capital 3.33% of their portfolio | 25.4k $2.6m | — |
| STATE STREET CORP 0.00% of their portfolio | 24.6k $2.5m | — |
| Caption Management, LLC 0.44% of their portfolio | 24.5k $2.5m | — |
| Mirae Asset Global Investments Co., Ltd. 0.01% of their portfolio | 23.5k $2.4m | — |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 23.0k $2.4m | — |
| CAPITAL FUND MANAGEMENT S.A. 0.06% of their portfolio | 22.0k $2.3m | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 20.6k $2.1m | — |
| Parkwood LLC 0.45% of their portfolio | 20.4k $2.1m | — |
| DekaBank Deutsche Girozentrale 0.01% of their portfolio | 20.0k $2.0m | — |
| HAP Trading, LLC 0.24% of their portfolio | 18.2k $1.9m | — |
| GROUP ONE TRADING LLC 0.06% of their portfolio | 17.4k $1.8m | — |
| Squarepoint Ops LLC 0.02% of their portfolio | 17.3k $1.8m | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 15.9k $1.6m | — |
| Advisors Asset Management, Inc. 0.03% of their portfolio | 15.8k $1.6m | — |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 15.5k $1.6m | — |
| BANQUE PICTET & CIE SA 0.02% of their portfolio | 15.3k $1.6m | — |