ARGENX SE ARGX
SPONSORED ADR · ADR · CUSIP 04016X101 · ISIN US04016X1019
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($515.4k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $393.78. Options: 17 managers hold calls ($90.7m notional), 15 hold puts ($105.0m).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 255 |
| Q4 2022 | 271 |
| Q1 2023 | 273 |
| Q2 2023 | 291 |
| Q3 2023 | 342 |
| Q4 2023 | 347 |
| Q1 2024 | 328 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 114 | 139 |
| Q1 2023 | 123 | 139 |
| Q2 2023 | 151 | 117 |
| Q3 2023 | 208 | 117 |
| Q4 2023 | 193 | 156 |
| Q1 2024 | 166 | 176 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $245.0m | $410.6m | 1.68 |
| Q3 2023 | $364.6m | $125.5m | 0.34 |
| Q4 2023 | $325.1m | $223.3m | 0.69 |
| Q1 2024 | $90.7m | $105.0m | 1.16 |
Biggest buyers
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.8m |
| T. Rowe Price Investment Management, Inc. | Added | +933.4k |
| MORGAN STANLEY | Added | +775.9k |
| JANUS HENDERSON GROUP PLC | Added | +439.9k |
| Clearbridge Investments, LLC | Added | +159.5k |
| BANK OF AMERICA CORP /DE/ | Added | +134.9k |
| Jefferies Financial Group Inc. | Added | +132.1k |
| Paradigm Biocapital Advisors LP | Added | +129.5k |
| Sofinnova Investments, Inc. | Added | +104.6k |
| AMERICAN CENTURY COMPANIES INC | Added | +100.1k |
Biggest sellers
| FMR LLC | Reduced | -542.4k |
| EcoR1 Capital, LLC | Sold out | -301.0k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -215.8k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Reduced | -166.1k |
| Logos Global Management LP | Sold out | -145.0k |
| GOLDMAN SACHS GROUP INC | Reduced | -130.9k |
| Assenagon Asset Management S.A. | Reduced | -121.2k |
| Artal Group S.A. | Sold out | -116.4k |
| Fairmount Funds Management LLC | Sold out | -112.9k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -109.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $45.5m115.5k shares |
| CITADEL ADVISORS LLC | Reduced | $13.2m33.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $5.5m14.0k shares |
| SAL Trading, LLC | Reduced | $4.8m12.1k shares |
| CITIGROUP INC | Reduced | $4.3m10.8k shares |
| GOLDMAN SACHS GROUP INC | Added | $3.9m10.0k shares |
| J. Goldman & Co LP | New | $3.1m8.0k shares |
| D. E. Shaw & Co., Inc. | Unchanged | $2.8m7.1k shares |
| Parallax Volatility Advisers, L.P. | New | $2.8m7.1k shares |
| JANE STREET GROUP, LLC | Reduced | $1.5m3.7k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $21.7m55.1k shares |
| JANE STREET GROUP, LLC | Added | $16.4m41.7k shares |
| D. E. Shaw & Co., Inc. | Unchanged | $13.0m32.9k shares |
| CITADEL ADVISORS LLC | Reduced | $11.7m29.7k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $9.6m24.5k shares |
| SAL Trading, LLC | Reduced | $8.0m20.2k shares |
| Parallax Volatility Advisers, L.P. | Added | $7.4m18.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $6.0m15.2k shares |
| CITIGROUP INC | New | $4.3m10.8k shares |
| Jefferies Financial Group Inc. | Reduced | $3.5m9.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
No one currently above 5% in the filings since 19 Dec 2024.
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (4.3%, 2026-08-14)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q1 2024.
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD/ 0.27% of their portfolio | 5.5m $2.2bn | Added +1.8m |
| FMR LLC 0.09% of their portfolio | 3.3m $1.3bn | Reduced -542.4k |
| Artisan Partners Limited Partnership 1.83% of their portfolio | 3.2m $1.3bn | Added +15.1k |
| JANUS HENDERSON GROUP PLC 0.48% of their portfolio | 2.2m $872.7m | Added +439.9k |
| T. Rowe Price Investment Management, Inc. 0.51% of their portfolio | 2.1m $832.9m | Added +933.4k |
| MORGAN STANLEY 0.02% of their portfolio | 2.1m $819.6m | Added +775.9k |
| Capital World Investors 0.12% of their portfolio | 1.9m $734.1m | Reduced -96.6k |
| Avoro Capital Advisors LLC 5.69% of their portfolio | 1.2m $487.6m | Added +3.9k |
| BlackRock Inc. 0.01% of their portfolio | 1.0m $412.3m | Added +55.3k |
| Bellevue Group AG 4.87% of their portfolio | 811.0k $319.3m | Reduced -58.2k |
| RTW INVESTMENTS, LP 3.88% of their portfolio | 667.2k $262.7m | Unchanged |
| Clearbridge Investments, LLC 0.19% of their portfolio | 596.3k $234.8m | Added +159.5k |
| Paradigm Biocapital Advisors LP 7.65% of their portfolio | 552.1k $217.4m | Added +129.5k |
| Holocene Advisors, LP 0.71% of their portfolio | 488.8k $192.5m | Reduced -39.9k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.05% of their portfolio | 425.5k $167.5m | Reduced -166.1k |
| Invesco Ltd. 0.04% of their portfolio | 419.2k $165.0m | Reduced -17.1k |
| SEI INVESTMENTS CO 0.19% of their portfolio | 331.1k $130.3m | Reduced -950 |
| Pictet Asset Management Holding SA 0.14% of their portfolio | 329.2k $129.6m | Added +15.9k |
| Deep Track Capital, LP 3.40% of their portfolio | 300.0k $118.1m | Unchanged |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 276.2k $108.7m | Reduced -3.0k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 273.6k $107.7m | Added +134.9k |
| FEDERATED HERMES, INC. 0.24% of their portfolio | 268.4k $105.7m | Reduced -88.1k |
| BAMCO INC /NY/ 0.28% of their portfolio | 266.7k $105.0m | Reduced -20.7k |
| ARMISTICE CAPITAL, LLC 2.77% of their portfolio | 264.0k $103.9m | Reduced -54.0k |
| AMERICAN CENTURY COMPANIES INC 0.06% of their portfolio | 255.8k $100.7m | Added +100.1k |
| JENNISON ASSOCIATES LLC 0.06% of their portfolio | 233.4k $91.9m | Reduced -34.8k |
| Rock Springs Capital Management LP 2.29% of their portfolio | 229.2k $90.3m | Unchanged |
| TD Asset Management Inc 0.08% of their portfolio | 223.7k $88.1m | Added +29.8k |
| BRAIDWELL LP 2.79% of their portfolio | 219.8k $86.5m | Added +66.6k |
| EVENTIDE ASSET MANAGEMENT, LLC 1.35% of their portfolio | 218.9k $86.2m | Reduced -26.9k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 167.1k $65.8m | Reduced -7.1k |
| Fiera Capital Corp 0.19% of their portfolio | 162.1k $63.8m | Reduced -1.3k |
| DEUTSCHE BANK AG\ 0.03% of their portfolio | 159.6k $62.8m | Reduced -29.8k |
| ORBIMED ADVISORS LLC 1.10% of their portfolio | 151.6k $59.7m | Added +67.0k |
| BAKER BROS. ADVISORS LP 0.75% of their portfolio | 151.2k $59.5m | Unchanged |
| Sofinnova Investments, Inc. 3.47% of their portfolio | 149.3k $58.8m | Added +104.6k |
| Jefferies Financial Group Inc. 1.07% of their portfolio | 135.1k $53.2m | Added +132.1k |
| MILLENNIUM MANAGEMENT LLC 0.04% of their portfolio | 129.7k $51.1m | Reduced -215.8k |
| Alyeska Investment Group, L.P. 0.32% of their portfolio | 129.2k $50.9m | Reduced -105.6k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.06% of their portfolio | 123.5k $48.6m | Reduced -22.7k |
| MONTANOVA CAPITAL, LLC 2.02% of their portfolio | 121.9k $48.0m | Added +68.2k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 121.4k $47.8m | Reduced -130.9k |
| BNP PARIBAS FINANCIAL MARKETS 0.06% of their portfolio | 119.0k $46.9m | Added +8.0k |
| MARSHALL WACE, LLP 0.08% of their portfolio | 116.6k $45.9m | Reduced -9.0k |
| CITADEL ADVISORS LLC 0.04% of their portfolio | 112.3k $44.2m | Reduced -76.1k |
| FIRST TRUST ADVISORS LP 0.04% of their portfolio | 104.7k $41.2m | Added +24.9k |
| D. E. Shaw & Co., Inc. 0.05% of their portfolio | 103.1k $40.6m | Reduced -67.6k |
| Boxer Capital, LLC 1.94% of their portfolio | 100.0k $39.4m | Reduced -60.0k |
| TimesSquare Capital Management, LLC 0.54% of their portfolio | 93.8k $36.9m | Reduced -18.9k |
| PFM Health Sciences, LP 1.70% of their portfolio | 86.8k $34.2m | Unchanged |
| Aberdeen Group plc 0.07% of their portfolio | 85.4k $33.6m | Added +12.0k |
| Eagle Health Investments LP 6.35% of their portfolio | 84.6k $33.3m | Unchanged |
| Checkpoint Capital L.P. 21.58% of their portfolio | 82.0k $32.3m | Added +12.0k |
| Legal & General Group Plc 0.01% of their portfolio | 81.1k $31.9m | Added +2.8k |
| First Turn Management, LLC 4.71% of their portfolio | 80.0k $31.5m | Reduced -3.4k |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1.44% of their portfolio | 76.7k $30.2m | New |
| Saturn V Capital Management LP 10.35% of their portfolio | 65.6k $25.8m | Added +14.4k |
| Point72 Asset Management, L.P. 0.07% of their portfolio | 63.2k $24.9m | Reduced -54.9k |
| Balyasny Asset Management L.P. 0.06% of their portfolio | 57.0k $22.5m | Reduced -108.3k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 55.4k $21.8m | Added +7.5k |
| Eversept Partners, LP 1.60% of their portfolio | 54.5k $21.5m | Reduced -31.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.02% of their portfolio | 54.4k $21.4m | Added +6.8k |
| Allspring Global Investments Holdings, LLC 0.03% of their portfolio | 50.6k $19.9m | Reduced -35.6k |
| VAN ECK ASSOCIATES CORP 0.03% of their portfolio | 50.3k $19.8m | Added +4.2k |
| Finepoint Capital LP 5.05% of their portfolio | 50.0k $19.7m | New |
| Vestal Point Capital, LP 1.63% of their portfolio | 50.0k $19.7m | New |
| RAYMOND JAMES & ASSOCIATES 0.01% of their portfolio | 49.5k $19.5m | Added +16.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 47.6k $18.7m | Added +5.3k |
| ROYAL LONDON ASSET MANAGEMENT LTD 0.05% of their portfolio | 47.5k $18.7m | Added +1.2k |
| Ensign Peak Advisors, Inc 0.03% of their portfolio | 45.9k $18.1m | Added +22.0k |
| Iron Triangle Partners LP 1.83% of their portfolio | 45.0k $17.7m | New |
| PGGM Investments 0.25% of their portfolio | 44.6k $17.6m | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 43.6k $17.2m | Added +5.2k |
| Thrivent Financial for Lutherans 0.03% of their portfolio | 42.2k $16.6m | Reduced -19.7k |
| Candriam S.C.A. 0.10% of their portfolio | 38.2k $15.0m | New |
| AXA S.A. 0.04% of their portfolio | 36.4k $14.3m | Reduced -49.8k |
| Artia Global Partners LP 3.31% of their portfolio | 34.2k $13.5m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 34.2k $13.5m | Added +2.9k |
| QVT Financial LP 1.19% of their portfolio | 32.5k $12.8m | Unchanged |
| SOROS FUND MANAGEMENT LLC 0.27% of their portfolio | 30.0k $11.8m | New |
| MOORE CAPITAL MANAGEMENT, LP 0.24% of their portfolio | 30.0k $11.8m | Added +5.0k |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 29.8k $11.7m | Reduced -105 |
| BARCLAYS PLC 0.01% of their portfolio | 29.2k $11.5m | Reduced -12.2k |
| NATIXIS ADVISORS, LLC 0.03% of their portfolio | 28.2k $11.1m | Added +13.8k |
| Tri Locum Partners LP 3.82% of their portfolio | 28.0k $11.0m | Added +3.8k |
| Squarepoint Ops LLC 0.05% of their portfolio | 27.9k $11.0m | Added +9.5k |
| Atika Capital Management LLC 1.18% of their portfolio | 26.7k $10.5m | Unchanged |
| Handelsbanken Fonder AB 0.05% of their portfolio | 26.6k $10.5m | Added +768 |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 26.2k $10.3m | Added +316 |
| PINEBRIDGE INVESTMENTS, L.P. 0.08% of their portfolio | 25.8k $10.2m | Added +3.3k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 25.5k $10.1m | Added +508 |
| AWM Investment Company, Inc. 1.29% of their portfolio | 25.0k $9.8m | Reduced -5.0k |
| Trexquant Investment LP 0.20% of their portfolio | 24.9k $9.8m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 23.9k $9.4m | Reduced -1.1k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 23.2k $9.3m | Reduced -3.7k |
| DCF Advisers, LLC 4.79% of their portfolio | 20.2k $8.0m | Reduced -250 |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 19.4k $7.6m | Reduced -6.5k |
| Walleye Capital LLC 0.08% of their portfolio | 18.9k $7.4m | Reduced -20.8k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 17.9k $7.1m | Added +72 |
| Erste Asset Management GmbH 0.09% of their portfolio | 16.8k $6.7m | Unchanged |