ARCUS BIOSCIENCES INC RCUS
COM · Common Stock · CUSIP 03969F109
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersHayward, CA
- Founded2015
- Websitearcusbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.3m this quarter). Holder counts are more reliable. Shares outstanding: 127.3m as of 2026-07-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $30.82. Options: 9 managers hold calls ($15.6m notional), 5 hold puts ($2.6m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 185 |
| Q4 2022 | 201 |
| Q1 2023 | 182 |
| Q2 2023 | 183 |
| Q3 2023 | 188 |
| Q4 2023 | 186 |
| Q1 2024 | 173 |
| Q2 2024 | 194 |
| Q3 2024 | 188 |
| Q4 2024 | 187 |
| Q1 2025 | 188 |
| Q2 2025 | 187 |
| Q3 2025 | 190 |
| Q4 2025 | 209 |
| Q1 2026 | 211 |
| Q2 2026 | 230 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 88 | 95 |
| Q4 2024 | 75 | 91 |
| Q1 2025 | 125 | 57 |
| Q2 2025 | 109 | 77 |
| Q3 2025 | 93 | 84 |
| Q4 2025 | 135 | 66 |
| Q1 2026 | 112 | 90 |
| Q2 2026 | 128 | 87 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $46.2m | $2.2m | 0.05 |
| Q4 2025 | $92.8m | $5.3m | 0.06 |
| Q1 2026 | $12.6m | $3.6m | 0.29 |
| Q2 2026 | $15.6m | $2.6m | 0.17 |
Biggest buyers
| FMR LLC | Added | +2.9m |
| CITADEL ADVISORS LLC | Added | +1.8m |
| BlackRock, Inc. | Added | +1.2m |
| Soleus Capital Management, L.P. | Added | +716.8k |
| STATE STREET CORP | Added | +616.6k |
| T. Rowe Price Investment Management, Inc. | New | +589.5k |
| Ikarian Capital, LLC | New | +504.6k |
| BAKER BROS. ADVISORS LP | Added | +429.2k |
| GOLDMAN SACHS GROUP INC | Added | +387.8k |
| JPMORGAN CHASE & CO | Added | +337.4k |
Biggest sellers
| MARSHALL WACE, LLP | Reduced | -1.8m |
| Trails Edge Capital Partners, LP | Sold out | -1.0m |
| Woodline Partners LP | Reduced | -770.0k |
| Siren, L.L.C. | Reduced | -586.6k |
| Logos Global Management LP | Reduced | -550.0k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -424.7k |
| SAMLYN CAPITAL, LLC | Reduced | -361.2k |
| MORGAN STANLEY | Reduced | -317.6k |
| Parkman Healthcare Partners LLC | Reduced | -288.0k |
| MONTANOVA CAPITAL, LLC | Reduced | -254.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $6.0m194.0k shares |
| DIADEMA PARTNERS LP | New | $3.8m124.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.5m49.1k shares |
| JANE STREET GROUP, LLC | Reduced | $1.1m36.9k shares |
| JPMORGAN CHASE & CO | New | $932.4k30.0k shares |
| NOMURA HOLDINGS INC | Reduced | $924.9k30.0k shares |
| CITADEL ADVISORS LLC | Reduced | $838.6k27.2k shares |
| GROUP ONE TRADING LLC | Reduced | $333.0k10.8k shares |
| Persistent Asset Partners Ltd | New | $98.0k316 shares |
Biggest puts
| JPMORGAN CHASE & CO | New | $932.4k30.0k shares |
| NOMURA HOLDINGS INC | Reduced | $924.9k30.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $706.0k22.9k shares |
| GROUP ONE TRADING LLC | Reduced | $30.8k1.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $24.7k800 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
GILEAD SCIENCES, INC.
13D · may seek influence
-0.9 pts · filed 2026-08-07
Stated purposeOn May 27, 2020, Gilead and the Issuer entered into an Option, License and Collaboration Agreement (the "Collaboration Agreement") pursuant to with Gilead obtained an exclusive option to acquire an exclusive license to all of the Issuer's current and future clinical programs during the 10-year collaboration term and, for those programs that enter clinical development prior to the end of the collaboration term, for up to an additional three years thereafter. In addition to the Collaboration Agreement, Gilead and the Issuer entered into a Common Stock Purchase Agreement (the "Purchase Agreement"), which was amended and restated on January 31, 2021 to account for the Second Purchase (the "Amended and Restated Purchase Agreement"), on June 27, 2023 to account for the Third Purchase (the "Seco… Full filing |
24.7% |
| BlackRock, Inc. 13G · institution +1.0 pts · filed 2026-01-08 | 10.4% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26), Point72 Asset Management, L.P. (4.1%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 2 | $57.0k | $57.0k |
| Q1 2025 | 2 | $402.8k | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 1 | $55.6k | $55.6k |
| Q4 2025 | 0 | — | 7 | $10.0m | $10.0m |
| Q1 2026 | 0 | — | 1 | $681.3k | $681.3k |
| Q2 2026 | 0 | — | 3 | $1.1m | $1.1m |
| Q3 2026 | 0 | — | 2 | $2.1m | $2.1m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-21 | Azoy Alexander Chief Accounting Officer | Sold plan | $84.8k2.8k shares |
| 2026-07-10 | Jaen Juan C. President · By Trust | Sold plan | $574.3k20.1k shares |
| 2026-07-09 | Jaen Juan C. President · By Trust | Sold plan | $1.5m48.5k shares |
| 2026-06-24 | Jaen Juan C. President · By Trust | Sold plan | $190.7k6.4k shares |
| 2026-06-23 | Jaen Juan C. President · By Trust | Sold plan | $437.1k15.8k shares |
| 2026-06-22 | Jaen Juan C. President · By Trust | Sold plan | $249.6k9.2k shares |
| 2026-06-01 | Azoy Alexander Chief Accounting Officer | Sold plan | $66.0k2.6k shares |
| 2026-05-11 | Goeltz II Robert C. Chief Financial Officer | Sold plan | $199.0k7.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| GILEAD SCIENCES, INC. 58.76% of their portfolio | 31.4m $968.8m | Unchanged |
| BlackRock, Inc. 0.01% of their portfolio | 16.4m $506.1m | Added +1.2m |
| STATE STREET CORP 0.01% of their portfolio | 6.0m $185.9m | Added +616.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.03% of their portfolio | 5.9m $181.8m | Reduced -194.1k |
| MONTANOVA CAPITAL, LLC 3.09% of their portfolio | 4.8m $147.3m | Reduced -254.6k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.01% of their portfolio | 4.5m $138.0m | Added +203.5k |
| FMR LLC 0.01% of their portfolio | 4.0m $124.9m | Added +2.9m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.9m $119.9m | Added +31.6k |
| CITADEL ADVISORS LLC 0.06% of their portfolio | 3.1m $96.7m | Added +1.8m |
| Woodline Partners LP 0.29% of their portfolio | 3.0m $92.7m | Reduced -770.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.4m $75.5m | Added +196.4k |
| Siren, L.L.C. 1.51% of their portfolio | 2.4m $74.6m | Reduced -586.6k |
| Fisher Asset Management, LLC 0.02% of their portfolio | 2.1m $66.0m | Reduced -51.0k |
| MARSHALL WACE, LLP 0.05% of their portfolio | 1.9m $60.0m | Reduced -1.8m |
| SAMLYN CAPITAL, LLC 0.79% of their portfolio | 1.5m $47.7m | Reduced -361.2k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.4m $44.2m | Added +8.1k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.04% of their portfolio | 1.4m $43.8m | Reduced -235.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.4m $42.8m | Added +387.8k |
| Soleus Capital Management, L.P. 1.24% of their portfolio | 1.2m $36.0m | Added +716.8k |
| Sofinnova Investments, Inc. 1.56% of their portfolio | 945.7k $29.2m | Added +22.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 941.8k $29.0m | Added +38.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 932.5k $28.7m | Added +92.2k |
| Parkman Healthcare Partners LLC 2.91% of their portfolio | 919.3k $28.3m | Reduced -288.0k |
| Invesco Ltd. 0.00% of their portfolio | 845.2k $26.1m | Added +24.4k |
| BAKER BROS. ADVISORS LP 0.13% of their portfolio | 844.8k $26.0m | Added +429.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 835.5k $25.8m | Added +189.4k |
| MORGAN STANLEY 0.00% of their portfolio | 795.9k $24.5m | Reduced -317.6k |
| Candriam S.C.A. 0.09% of their portfolio | 662.0k $20.4m | Reduced -128.6k |
| Aberdeen Group plc 0.03% of their portfolio | 650.7k $20.1m | Reduced -119.1k |
| Logos Global Management LP 0.86% of their portfolio | 650.0k $20.0m | Reduced -550.0k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 635.4k $19.6m | Added +322.7k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 616.1k $19.0m | Added +33.2k |
| T. Rowe Price Investment Management, Inc. 0.01% of their portfolio | 589.5k $18.2m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 543.0k $16.7m | Added +31.8k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.06% of their portfolio | 512.1k $15.8m | Added +81.7k |
| Ikarian Capital, LLC 2.55% of their portfolio | 504.6k $15.6m | New |
| Decheng Capital LLC 1.96% of their portfolio | 464.8k $14.3m | Reduced -13.0k |
| DAFNA Capital Management LLC 2.60% of their portfolio | 441.8k $13.6m | Reduced -2.0k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 423.4k $13.1m | Added +9.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 418.2k $13.1m | Added +337.4k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.02% of their portfolio | 379.1k $11.7m | Unchanged |
| UBS Group AG 0.00% of their portfolio | 369.1k $11.4m | Added +80.2k |
| Patient Square Capital LP 1.70% of their portfolio | 355.8k $11.0m | Added +160.8k |
| PDT Partners, LLC 0.52% of their portfolio | 323.6k $10.0m | Reduced -64.8k |
| Public Sector Pension Investment Board 0.02% of their portfolio | 298.2k $9.2m | Reduced -5.2k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 271.4k $8.4m | Added +258.3k |
| Nuveen, LLC 0.00% of their portfolio | 234.1k $7.2m | Added +12.3k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 225.0k $6.9m | Reduced -56.7k |
| DIADEMA PARTNERS LP 2.44% of their portfolio | 223.8k $6.9m | Reduced -14.3k |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 219.2k $6.8m | Reduced -22.3k |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 215.6k $6.6m | Reduced -37.3k |
| Legal & General Group Plc 0.00% of their portfolio | 191.6k $5.9m | Added +2.9k |
| Rock Springs Capital Management LP 0.27% of their portfolio | 180.0k $5.5m | Unchanged |
| Swiss National Bank 0.00% of their portfolio | 176.1k $5.4m | Added +4.8k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 154.4k $4.8m | Reduced -3.9k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.09% of their portfolio | 154.3k $4.8m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 153.8k $4.7m | Reduced -6.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 153.1k $4.7m | Reduced -228.7k |
| PFM Health Sciences, LP 0.41% of their portfolio | 152.1k $4.7m | New |
| Hudson Bay Capital Management LP 0.02% of their portfolio | 140.0k $4.3m | Reduced -216.5k |
| Man Group plc 0.01% of their portfolio | 137.8k $4.2m | Added +56.9k |
| PLATINUM INVESTMENT MANAGEMENT LTD 1.02% of their portfolio | 134.2k $4.1m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 133.1k $4.1m | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 127.0k $2.7m | Added +2.9k |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 122.6k $3.8m | Reduced -71.0k |
| CITIGROUP INC 0.00% of their portfolio | 112.2k $3.5m | Added +85.8k |
| SECTORAL ASSET MANAGEMENT INC 2.39% of their portfolio | 110.9k $3.4m | Added +65.8k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 110.6k $3.4m | Added +22.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 97.4k $3.0m | Reduced -8.4k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 96.4k $3.0m | Reduced -163.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 94.7k $2.9m | Added +20.9k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 92.4k $2.9m | Added +2.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 89.2k $2.8m | Added +13.4k |
| Parallel Advisors, LLC 0.04% of their portfolio | 86.6k $2.7m | Unchanged |
| Odyssean, LLC 0.43% of their portfolio | 85.5k $2.6m | New |
| Tidal Investments LLC 0.01% of their portfolio | 85.1k $2.6m | Reduced -1.2k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 83.9k $2.6m | Reduced -2.4k |
| Tema ETFs LLC 0.08% of their portfolio | 83.1k $2.6m | First filing |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 82.9k $2.6m | Added +47.2k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 82.4k $2.5m | Added +23.2k |
| Jump Financial, LLC 0.02% of their portfolio | 82.0k $2.5m | Reduced -53.8k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 81.5k $2.5m | Added +716 |
| Knott David M Jr 1.32% of their portfolio | 81.2k $2.5m | Unchanged |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 78.7k $2.4m | Added +8.8k |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 71.7k $2.2m | Reduced -43.4k |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 70.5k $2.2m | Unchanged |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 63.5k $2.0m | Added +7.6k |
| Caption Management, LLC 0.07% of their portfolio | 62.0k $1.9m | Added +46.0k |
| FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio | 60.5k $1.9m | New |
| BIT Capital GmbH 0.06% of their portfolio | 60.0k $1.8m | New |
| Corient Private Wealth LP 0.00% of their portfolio | 59.1k $1.8m | Added +35.0k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 59.0k $1.8m | Added +8.0k |
| Quantinno Capital Management LP 0.00% of their portfolio | 57.3k $1.8m | Added +40.0k |
| Persistent Asset Partners Ltd 0.55% of their portfolio | 57.0k $1.8m | Reduced -3.2k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 53.7k $1.7m | Added +15.9k |
| Susquehanna Portfolio Strategies, LLC 0.03% of their portfolio | 53.7k $1.7m | Reduced -186.3k |
| WINTON GROUP Ltd 0.05% of their portfolio | 52.4k $1.6m | Added +19.6k |
| MetLife Investment Management, LLC 0.01% of their portfolio | 52.1k $1.6m | Added +7.3k |
| Illinois Municipal Retirement Fund 0.02% of their portfolio | 51.2k $1.6m | Added +15.0k |
| SummitTX Capital, L.P. 0.04% of their portfolio | 50.5k $1.6m | Added +16.2k |