ARDELYX INC ARDX
COM · Common Stock · CUSIP 039697107 · ISIN US0396971071
Company in Fremont, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersFremont, CA
- Founded2007
- Websiteardelyx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($5.8m this quarter). Holder counts are more reliable. Shares outstanding: 238.4m as of 2025-02-14, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $5.07. Options: 13 managers hold calls ($14.5m notional), 10 hold puts ($18.9m).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 84 |
| Q4 2022 | 106 |
| Q1 2023 | 131 |
| Q2 2023 | 147 |
| Q3 2023 | 151 |
| Q4 2023 | 163 |
| Q1 2024 | 190 |
| Q2 2024 | 198 |
| Q3 2024 | 204 |
| Q4 2024 | 214 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 92 | 43 |
| Q2 2023 | 87 | 65 |
| Q3 2023 | 81 | 62 |
| Q4 2023 | 103 | 59 |
| Q1 2024 | 113 | 81 |
| Q2 2024 | 104 | 95 |
| Q3 2024 | 103 | 87 |
| Q4 2024 | 111 | 95 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $22.8m | $21.0m | 0.92 |
| Q2 2024 | $18.0m | $20.6m | 1.14 |
| Q3 2024 | $17.4m | $17.9m | 1.03 |
| Q4 2024 | $14.5m | $18.9m | 1.30 |
Biggest buyers
| JANUS HENDERSON GROUP PLC | Added | +2.9m |
| Two Seas Capital LP | New | +1.9m |
| Rock Springs Capital Management LP | New | +1.5m |
| D. E. Shaw & Co., Inc. | Added | +1.5m |
| MACQUARIE GROUP LTD | Added | +1.4m |
| Point72 Asset Management, L.P. | New | +1.3m |
| ALGERT GLOBAL LLC | New | +983.1k |
| VANGUARD GROUP INC | Added | +767.1k |
| ORACLE INVESTMENT MANAGEMENT INC | Added | +720.2k |
| Trexquant Investment LP | Added | +702.5k |
Biggest sellers
| EVENTIDE ASSET MANAGEMENT, LLC | Reduced | -1.8m |
| Rubric Capital Management LP | Reduced | -1.4m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -1.0m |
| ExodusPoint Capital Management, LP | Sold out | -921.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -911.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -755.0k |
| MORGAN STANLEY | Reduced | -712.8k |
| STATE STREET CORP | Reduced | -548.9k |
| JPMORGAN CHASE & CO | Reduced | -539.6k |
| Vestal Point Capital, LP | Sold out | -500.0k |
Biggest calls
| ORACLE INVESTMENT MANAGEMENT INC | Added | $3.0m584.7k shares |
| J. Goldman & Co LP | Added | $2.9m580.7k shares |
| GROUP ONE TRADING LLC | Reduced | $2.9m573.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.1m417.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.3m247.9k shares |
| CITADEL ADVISORS LLC | Reduced | $1.2m226.9k shares |
| JANE STREET GROUP, LLC | Added | $402.1k79.3k shares |
| WOLVERINE TRADING, LLC | Added | $300.3k57.2k shares |
| IMC-Chicago, LLC | New | $230.7k45.5k shares |
| Caption Management, LLC | Unchanged | $202.8k40.0k shares |
Biggest puts
| JANE STREET GROUP, LLC | Added | $7.9m1.5m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.1m620.0k shares |
| CITADEL ADVISORS LLC | Added | $2.7m540.7k shares |
| GROUP ONE TRADING LLC | Added | $2.6m511.5k shares |
| BANK OF AMERICA CORP /DE/ | Unchanged | $1.1m216.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $653.0k128.9k shares |
| WOLVERINE TRADING, LLC | Added | $375.4k71.5k shares |
| Squarepoint Ops LLC | New | $235.8k46.5k shares |
| SIG BROKERAGE, LP | First filing | $196.7k38.8k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Rubric Capital Management LP 13G · institution new · filed 2026-08-14 | 6.6% |
| INTEGRATED CORE STRATEGIES (US) LLC 13G · passive investor -1.7 pts · filed 2026-08-11 | 5.7% |
| STATE STREET CORP 13G · institution +0.6 pts · filed 2026-05-12 | 5.5% |
Fell to 5% or below in the last year: JANUS HENDERSON GROUP PLC (3.4%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 8 | $122.8k | — |
| Q2 2023 | 0 | — | 8 | $309.6k | $121.0k |
| Q3 2023 | 0 | — | 8 | $115.6k | $13.2k |
| Q4 2023 | 0 | — | 8 | $2.2m | $1.9m |
| Q1 2024 | 0 | — | 8 | $1.5m | $1.0m |
| Q2 2024 | 0 | — | 8 | $7.6m | $1.5m |
| Q3 2024 | 0 | — | 7 | $1.5m | $870.7k |
| Q4 2024 | 1 | $2.0m | 6 | $1.1m | $472.3k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-12-19 | MOTT DAVID M Director | Bought | $996.1k213.3k shares |
| 2024-12-10 | RAAB MICHAEL President & CEO, director | Sold plan | $131.5k25.0k shares |
| 2024-11-25 | RAAB MICHAEL President & CEO, director | Sold plan | $134.5k25.0k shares |
| 2024-11-20 | RAAB MICHAEL President & CEO, director | Sold | $153.2k32.0k shares |
| 2024-11-20 | Williams Laura A Chief Medical Officer | Sold | $35.3k7.4k shares |
| 2024-11-20 | GRAMMER ELIZABETH A Officer | Sold | $33.8k7.0k shares |
| 2024-11-20 | Renz Justin A Chief Financial Officer | Sold | $25.2k5.3k shares |
| 2024-11-20 | Rosenbaum David P. Chief Development Officer | Sold | $23.7k4.9k shares |
| 2024-11-20 | Blanks Robert Officer | Sold | $23.7k4.9k shares |
| 2024-11-20 | Rosenbaum David P. Chief Development Officer | Sold | $10.7k2.2k shares |
| 2024-11-13 | MOTT DAVID M Director | Bought | $997.3k215.9k shares |
| 2024-11-11 | RAAB MICHAEL President & CEO, director | Sold plan | $13.4k2.7k shares |
| 2024-11-06 | Rosenbaum David P. Chief Development Officer · By Wife | Sold | $165.7k27.2k shares |
| 2024-11-04 | Rosenbaum David P. Chief Development Officer · By Wife | Sold | $161.7k27.2k shares |
| 2024-10-28 | RAAB MICHAEL President & CEO, director | Sold plan | $147.8k25.0k shares |
| 2024-10-11 | RAAB MICHAEL President & CEO, director | Sold plan | $45.1k7.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| JANUS HENDERSON GROUP PLC 0.06% of their portfolio | 24.4m $123.6m | Added +2.9m |
| BlackRock, Inc. 0.00% of their portfolio | 18.5m $93.9m | Added +694.5k |
| VANGUARD GROUP INC 0.00% of their portfolio | 14.4m $72.8m | Added +767.1k |
| STATE STREET CORP 0.00% of their portfolio | 11.6m $58.8m | Reduced -548.9k |
| MACQUARIE GROUP LTD 0.06% of their portfolio | 10.3m $52.5m | Added +1.4m |
| EVENTIDE ASSET MANAGEMENT, LLC 0.52% of their portfolio | 5.6m $28.4m | Reduced -1.8m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 5.5m $27.9m | Added +22.0k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 3.0m $15.0m | Reduced -1.0m |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 2.5m $12.6m | Added +281.7k |
| MORGAN STANLEY 0.00% of their portfolio | 2.4m $12.3m | Reduced -712.8k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 2.2m $11.0m | Added +4.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 2.2m $10.9m | Reduced -212.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 2.2m $10.9m | Added +50.4k |
| ORACLE INVESTMENT MANAGEMENT INC 7.11% of their portfolio | 2.1m $10.6m | Added +720.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 2.0m $10.3m | Added +96.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.9m $9.8m | Added +63.0k |
| Two Seas Capital LP 1.11% of their portfolio | 1.9m $9.4m | New |
| Rubric Capital Management LP 0.16% of their portfolio | 1.7m $8.7m | Reduced -1.4m |
| Redmile Group, LLC 0.56% of their portfolio | 1.6m $8.0m | Reduced -84.5k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.5m $7.4m | Added +1.5m |
| Rock Springs Capital Management LP 0.28% of their portfolio | 1.5m $7.4m | New |
| JONES FINANCIAL COMPANIES LLLP 0.01% of their portfolio | 1.5m $7.4m | Added +583.5k |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 1.3m $6.8m | New |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 1.2m $6.2m | Reduced -31.3k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 1.1m $5.8m | Added +157.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 986.4k $5.0m | Reduced -755.0k |
| ALGERT GLOBAL LLC 0.12% of their portfolio | 983.1k $5.0m | New |
| Propel Bio Management, LLC 4.79% of their portfolio | 950.9k $4.8m | Reduced -120.0k |
| Trexquant Investment LP 0.05% of their portfolio | 906.3k $4.6m | Added +702.5k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio | 895.7k $4.5m | Added +176.9k |
| Aberdeen Group plc 0.01% of their portfolio | 851.7k $4.3m | Unchanged |
| Hennion & Walsh Asset Management, Inc. 0.19% of their portfolio | 808.4k $4.1m | Added +164.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 715.0k $3.6m | Reduced -1.5k |
| UBS Group AG 0.00% of their portfolio | 714.8k $3.6m | Added +192.3k |
| Simplify Asset Management Inc. 0.24% of their portfolio | 689.4k $3.5m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 650.0k $3.3m | New |
| Knott David M Jr 1.12% of their portfolio | 612.3k $3.1m | Reduced -70.6k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 593.7k $3.0m | Added +400.1k |
| OBERWEIS ASSET MANAGEMENT INC/ 0.14% of their portfolio | 579.3k $2.9m | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 578.3k $2.9m | Added +142.3k |
| Pekin Hardy Strauss, Inc. 0.35% of their portfolio | 548.0k $2.8m | Added +1.6k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 545.2k $2.8m | Reduced -73.3k |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 534.7k $2.7m | Reduced -59.7k |
| BARCLAYS PLC 0.00% of their portfolio | 532.7k $2.7m | Reduced -14.7k |
| Palisades Investment Partners, LLC 1.11% of their portfolio | 517.8k $2.6m | Added +34.4k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 469.8k $2.4m | Added +299.3k |
| Swiss National Bank 0.00% of their portfolio | 463.1k $2.3m | Added +4.8k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 446.4k $2.3m | Reduced -210 |
| GROUP ONE TRADING LLC 0.08% of their portfolio | 444.8k $2.3m | Reduced -161.9k |
| CITIGROUP INC 0.00% of their portfolio | 432.5k $2.2m | Added +257.7k |
| MACKENZIE FINANCIAL CORP 0.00% of their portfolio | 420.4k $2.1m | Added +382.1k |
| Cubist Systematic Strategies, LLC 0.03% of their portfolio | 375.5k $1.9m | New |
| Lion Point Capital, LP 8.90% of their portfolio | 335.4k $1.7m | Reduced -34.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 327.9k $1.7m | Added +66.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 326.1k $1.7m | Added +6.1k |
| CAPITAL FUND MANAGEMENT S.A. 0.02% of their portfolio | 313.1k $1.6m | Added +217.3k |
| Clay Northam Wealth Management, LLC 1.01% of their portfolio | 307.7k $1.6m | Added +26.2k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 281.8k $1.4m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 280.3k $1.4m | Added +98.9k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 268.9k $1.4m | Reduced -305.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 263.8k $1.3m | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 248.5k $1.3m | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 243.4k $1.2m | Added +4.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 234.7k $1.2m | Reduced -539.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 220.2k $1.1m | Reduced -1.1k |
| HUSSMAN STRATEGIC ADVISORS, INC. 0.31% of their portfolio | 210.0k $1.1m | Reduced -147.0k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 183.5k $930.3k | First filing |
| Parkman Healthcare Partners LLC 0.12% of their portfolio | 177.8k $901.4k | Added +50.9k |
| SIMPLEX TRADING, LLC 0.02% of their portfolio | 169.9k $861.0k | Reduced -70.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 162.8k $826.0k | Reduced -911.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 162.7k $824.7k | Reduced -161.0k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 158.3k $802.5k | Reduced -2.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 154.6k $787.8k | Added +3.5k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 148.1k $751.1k | Added +12.7k |
| XTX Topco Ltd 0.06% of their portfolio | 140.5k $712.2k | Added +110.5k |
| LPL Financial LLC 0.00% of their portfolio | 138.8k $703.7k | Reduced -58.6k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 135.2k $685.2k | Added +10.2k |
| PFG Investments, LLC 0.04% of their portfolio | 134.0k $679.5k | Reduced -100 |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 131.2k $665.2k | Reduced -169.7k |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 126.5k $641.5k | New |
| Invesco Ltd. 0.00% of their portfolio | 124.9k $633.5k | Added +10.5k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 117.1k $593.8k | Reduced -130.8k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 117.0k $593.0k | Reduced -7.3k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 114.8k $582.1k | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 107.3k $544.2k | Reduced -10.9k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 104.2k $528.3k | Unchanged |
| PROFUND ADVISORS LLC 0.02% of their portfolio | 103.4k $524.4k | Reduced -13.9k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 100.0k $529.0k | Unchanged |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 99.7k $505.6k | Added +38.3k |
| Tyler-Stone Wealth Management 0.09% of their portfolio | 96.2k $488.0k | Reduced -600 |
| NATIXIS 0.00% of their portfolio | 93.8k $475.4k | New |
| B. Riley Wealth Advisors, Inc. 0.01% of their portfolio | 90.0k $456.3k | Unchanged |
| Henshaw Capital LLC 0.02% of their portfolio | 79.6k $403.8k | Added +27.2k |
| Inspire Investing, LLC 0.05% of their portfolio | 79.4k $402.7k | Added +19.6k |
| ProShare Advisors LLC 0.00% of their portfolio | 77.5k $392.8k | Added +19.6k |
| Parallax Volatility Advisers, L.P. 0.01% of their portfolio | 75.1k $380.8k | Added +1.6k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 74.9k $379.5k | Added +11.7k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 74.0k $374.9k | Added +2.2k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 70.2k $355.7k | Reduced -5.5k |
| Graham Capital Management, L.P. 0.01% of their portfolio | 69.9k $354.6k | Added +39.8k |