Vault-13

AKERO THERAPEUTICS INC AKRO

COM · Common Stock · CUSIP 00973Y108

154 institutional holders -20 vs Q1 2024
72,907,30572.9m shares reported held*
$1.7bnreported value*
15 new 61 added 53 reduced 34 sold out net sold ≈ $26.2m (-1.1m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($5.8m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $23.46. Options: 7 managers hold calls ($6.0m notional), 7 hold puts ($7.7m).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 146Q4 22: 162Q1 23: 157Q2 23: 159Q3 23: 183Q4 23: 158Q1 24: 174Q2 24: 154154Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 2022146
Q4 2022162
Q1 2023157
Q2 2023159
Q3 2023183
Q4 2023158
Q1 2024174
Q2 2024154

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 103 bought or addedQ4 22: 60 cut or sold outQ4 22Q1 23: 75 bought or addedQ1 23: 77 cut or sold outQ2 23: 96 bought or addedQ2 23: 64 cut or sold outQ2 23Q3 23: 115 bought or addedQ3 23: 50 cut or sold outQ4 23: 81 bought or addedQ4 23: 99 cut or sold outQ4 23Q1 24: 111 bought or addedQ1 24: 66 cut or sold outQ2 24: 76 bought or addedQ2 24: 87 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 202210360
Q1 20237577
Q2 20239664
Q3 202311550
Q4 20238199
Q1 202411166
Q2 20247687

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150m$200mQ3 23 calls: $139.6mQ3 23 puts: $150.8mQ3 23P/C 1.08Q4 23 calls: $42.9mQ4 23 puts: $12.4mQ4 23P/C 0.29Q1 24 calls: $16.1mQ1 24 puts: $20.0mQ1 24P/C 1.24Q2 24 calls: $6.0mQ2 24 puts: $7.7mQ2 24P/C 1.29
Numbers
QuarterCallsPutsP/C
Q3 2023$139.6m$150.8m1.08
Q4 2023$42.9m$12.4m0.29
Q1 2024$16.1m$20.0m1.24
Q2 2024$6.0m$7.7m1.29

Biggest buyers

BRAIDWELL LP New +1,084,400+1.1m
Logos Global Management LP Added +800,000+800.0k
JANUS HENDERSON GROUP PLC Added +754,283+754.3k
BlackRock Inc. Added +694,021+694.0k
T. Rowe Price Investment Management, Inc. Added +665,194+665.2k
JPMORGAN CHASE & CO Added +433,736+433.7k
Long Focus Capital Management, LLC Added +391,000+391.0k
ALLIANCEBERNSTEIN L.P. Added +286,595+286.6k
SILVERARC CAPITAL MANAGEMENT, LLC Added +225,138+225.1k
Rheos Capital Works Inc. New +216,000+216.0k

Biggest sellers

BAKER BROS. ADVISORS LP Reduced -1,616,123-1.6m
FRED ALGER MANAGEMENT, LLC Reduced -1,213,093-1.2m
STATE STREET CORP Reduced -1,108,304-1.1m
MILLENNIUM MANAGEMENT LLC Reduced -622,984-623.0k
Artisan Partners Limited Partnership Sold out -303,920-303.9k
Point72 Asset Management, L.P. Sold out -289,106-289.1k
MORGAN STANLEY Reduced -265,061-265.1k
Schonfeld Strategic Advisors LLC Reduced -253,929-253.9k
Redmile Group, LLC Reduced -244,229-244.2k
Candriam S.C.A. Sold out -240,000-240.0k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $2.7m114.8k shares
CITADEL ADVISORS LLC Reduced $1.4m57.8k shares
SIMPLEX TRADING, LLC Reduced $997.0k42.5k shares
GROUP ONE TRADING LLC Reduced $518.5k22.1k shares
JANE STREET GROUP, LLC Reduced $349.6k14.9k shares
Walleye Capital LLC Reduced $75.1k3.2k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

JANE STREET GROUP, LLC Reduced $4.0m169.5k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.9m83.1k shares
CITADEL ADVISORS LLC Reduced $1.1m47.0k shares
SIMPLEX TRADING, LLC Reduced $581.0k24.8k shares
Walleye Capital LLC New $77.4k3.3k shares
GROUP ONE TRADING LLC Reduced $58.6k2.5k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
GENERAL ATLANTIC, L.P. 13G · passive investor filed 2025-05-15 8.4% 6.8m 2025-05-15

Fell to 5% or below in the last year: JANUS HENDERSON GROUP PLC (4.1%, 2026-02-17), RTW INVESTMENTS, LP (0.0%, 2026-02-17), Deep Track Capital, LP (0.0%, 2026-02-13), WELLINGTON MANAGEMENT GROUP LLP (0.0%, 2026-02-10), PRICE T ROWE ASSOCIATES INC /MD/ (4.8%, 2025-11-14)

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 JANUS HENDERSON GROUP PLC 0.09% of their portfolio LONDON, X0 6,876,2536.9m $161.3m $161.3m 0.09% Added +754.3k +754,283
2 BlackRock Inc. 0.00% of their portfolio New York, NY 5,586,6375.6m $131.1m $131.1m 0.00% Added +694.0k +694,021
3 RTW INVESTMENTS, LP 1.97% of their portfolio NEW YORK, NY 5,431,9855.4m $127.4m $127.4m 1.97% Unchanged
4 GENERAL ATLANTIC, L.P. 3.86% of their portfolio New York, NY 5,233,9895.2m $122.8m $122.8m 3.86% Unchanged
5 WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio Boston, MA 5,114,6035.1m $120.0m $120.0m 0.02% Reduced -98.8k -98,761
6 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 4,146,3514.1m $97.3m $97.3m 0.01% Added +85.9k +85,872
7 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 3,705,0903.7m $86.9m $86.9m 0.00% Added +35.2k +35,167
8 ALKEON CAPITAL MANAGEMENT LLC 0.40% of their portfolio New York, NY 3,327,2203.3m $78.1m $78.1m 0.40% Unchanged
9 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,689,4262.7m $63.1m $63.1m 0.00% Reduced -1.1m -1,108,304
10 ALLIANCEBERNSTEIN L.P. 0.02% of their portfolio NASHVILLE, TN 1,907,8571.9m $44.8m $44.8m 0.02% Added +286.6k +286,595
11 T. Rowe Price Investment Management, Inc. 0.03% of their portfolio BALTIMORE, MD 1,767,2431.8m $41.5m $41.5m 0.03% Added +665.2k +665,194
12 Boxer Capital, LLC 2.07% of their portfolio San Diego, CA 1,676,7331.7m $39.3m $39.3m 2.07% Unchanged
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,619,0391.6m $38.0m $38.0m 0.00% Added +199.7k +199,732
14 Redmile Group, LLC 2.29% of their portfolio LARKSPUR, CA 1,614,4731.6m $37.9m $37.9m 2.29% Reduced -244.2k -244,229
15 Logos Global Management LP 2.18% of their portfolio San Francisco, CA 1,600,0001.6m $37.5m $37.5m 2.18% Added +800.0k +800,000
16 PERCEPTIVE ADVISORS LLC 0.85% of their portfolio NEW YORK, NY 1,499,8971.5m $35.2m $35.2m 0.85% Added +112.4k +112,426
17 Yiheng Capital Management, L.P. 4.74% of their portfolio SAN FRANCISCO, CA 1,434,1791.4m $33.6m $33.6m 4.74% Unchanged
18 BAKER BROS. ADVISORS LP 0.33% of their portfolio NEW YORK, NY 1,097,0821.1m $25.7m $25.7m 0.33% Reduced -1.6m -1,616,123
19 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1,084,5341.1m $25.4m $25.4m 0.00% Added +433.7k +433,736
20 BRAIDWELL LP 0.80% of their portfolio STAMFORD, CT 1,084,4001.1m $25.4m $25.4m 0.80% New
21 Rock Springs Capital Management LP 0.76% of their portfolio Baltimore, MD 1,074,2611.1m $25.2m $25.2m 0.76% Reduced -225.6k -225,627
22 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 946,528946.5k $22.2m $22.2m 0.00% Reduced -265.1k -265,061
23 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 782,950783.0k $18.4m $18.4m 0.00% Added +193.1k +193,098
24 Long Focus Capital Management, LLC 1.75% of their portfolio SAN JUAN, PR 719,604719.6k $16.9m $16.9m 1.75% Added +391.0k +391,000
25 SILVERARC CAPITAL MANAGEMENT, LLC 3.62% of their portfolio BOSTON, MA 625,087625.1k $14.7m $14.7m 3.62% Added +225.1k +225,138
26 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 587,866587.9k $13.8m $13.8m 0.00% Reduced -9.8k -9,822
27 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 554,865554.9k $13.0m $13.0m 0.00% Added +36.6k +36,579
28 EMERALD ADVISERS, LLC 0.51% of their portfolio LEOLA, PA 515,252515.3k $12.1m $12.1m 0.51% Reduced -23.6k -23,621
29 Schonfeld Strategic Advisors LLC 0.08% of their portfolio NEW YORK, NY 441,794441.8k $10.4m $10.4m 0.08% Reduced -253.9k -253,929
30 EMERALD MUTUAL FUND ADVISERS TRUST 0.52% of their portfolio LEOLA, PA 424,901424.9k $10.0m $10.0m 0.52% Unchanged
31 University of Wisconsin Foundation 11.19% of their portfolio MADISON, WI 423,849423.8k $9.9m $9.9m 11.19% Added +51.3k +51,274
32 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 395,117395.1k $9.3m $9.3m 0.01% Reduced -24.5k -24,543
33 MPM BIOIMPACT LLC 1.41% of their portfolio BOSTON, MA 385,990386.0k $9.1m $9.1m 1.41% Added +53.1k +53,066
34 Propel Bio Management, LLC 4.99% of their portfolio Los Angeles, CA 327,752327.8k $7.7m $7.7m 4.99% Unchanged
35 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 326,047326.0k $7.6m $7.6m 0.00% Reduced -708 -708
36 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 315,717315.7k $7.4m $7.4m 0.01% Reduced -91.4k -91,408
37 Octagon Capital Advisors LP 1.10% of their portfolio NEW YORK, NY 283,372283.4k $6.6m $6.6m 1.10% Reduced -56.6k -56,628
38 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 262,230262.2k $6.2m $6.2m 0.00% Reduced -163.6k -163,641
39 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 257,534257.5k $6.0m $6.0m 0.01% Added +7.5k +7,459
40 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 251,234251.2k $5.9m $5.9m 0.00% Added +62.0k +61,988
41 SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio London, X0 246,463246.5k $5.8m $5.8m 0.01% Added +75.5k +75,507
42 Simplify Asset Management Inc. 0.51% of their portfolio Las Vegas, NV 245,487245.5k $5.8m $5.8m 0.51% Reduced -189 -189
43 Ensign Peak Advisors, Inc 0.01% of their portfolio SALT LAKE CITY, UT 237,494237.5k $5.6m $5.6m 0.01% Added +5.0k +4,950
44 Rheos Capital Works Inc. 0.27% of their portfolio Tokyo, M0 216,000216.0k $5.1m $5.1m 0.27% New
45 Woodline Partners LP 0.05% of their portfolio San Francisco, CA 200,432200.4k $4.7m $4.7m 0.05% Added +72.0k +71,991
46 Aberdeen Group plc 0.01% of their portfolio EDINBURGH, X0 199,237199.2k $4.7m $4.7m 0.01% Unchanged
47 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio JUPITER, FL 193,836193.8k $4.5m $4.5m 0.02% New
48 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 174,903174.9k $4.1m $4.1m 0.00% Added +30.0k +30,040
49 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 169,591169.6k $4.0m $4.0m 0.00% Reduced -623.0k -622,984
50 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 154,592154.6k $3.6m $3.6m 0.00% Added +29.6k +29,600
51 SPHERA FUNDS MANAGEMENT LTD. 0.54% of their portfolio TEL AVIV, L3 141,620141.6k $3.3m $3.3m 0.54% Reduced -18.8k -18,825
52 PDT Partners, LLC 0.31% of their portfolio New York, NY 139,296139.3k $3.3m $3.3m 0.31% Added +14.8k +14,848
53 FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio NEW YORK, NY 123,788123.8k $2.9m $2.9m 0.01% Reduced -1.2m -1,213,093
54 Rafferty Asset Management, LLC 0.01% of their portfolio New York, NY 121,014121.0k $2.8m $2.8m 0.01% Reduced -173.1k -173,099
55 TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio NEW YORK, NY 120,074120.1k $2.8m $2.8m 0.01% Added +75.8k +75,787
56 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 115,788115.8k $2.7m $2.7m 0.00% Added +75.9k +75,937
57 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 107,338107.3k $2.5m $2.5m 0.00% Added +24.9k +24,940
58 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 107,172107.2k $2.5m $2.5m 0.00% Added +22.2k +22,195
59 Swiss National Bank 0.00% of their portfolio ZURICH, V8 102,000102.0k $2.4m $2.4m 0.00% Reduced -3.0k -3,000
60 UBS Group AG 0.00% of their portfolio ZURICH, V8 71,11171.1k $1.7m $1.7m 0.00% Reduced -136.9k -136,890
61 Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio VANCOUVER, A1 69,99570.0k $1.6m $1.6m 0.01% Reduced -32.6k -32,607
62 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 65,61465.6k $1.5m $1.5m 0.00% Added +19.1k +19,075
63 ALGERT GLOBAL LLC 0.05% of their portfolio SAN FRANCISCO, CA 62,86162.9k $1.5m $1.5m 0.05% Reduced -24.6k -24,562
64 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 56,01656.0k $1.3m $1.3m 0.00% Reduced -14.7k -14,665
65 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 53,93953.9k $1.3m $1.3m 0.01% Added +14.2k +14,230
66 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 51,82151.8k $1.2m $1.2m 0.00% Reduced -2.4k -2,364
67 Legal & General Group Plc 0.00% of their portfolio London, X0 51,37751.4k $1.2m $1.2m 0.00% Added +1.4k +1,450
68 Erste Asset Management GmbH 0.01% of their portfolio VIENNA, C4 47,00047.0k $1.1m $1.1m 0.01% Unchanged
69 Jump Financial, LLC 0.02% of their portfolio Chicago, IL 45,55345.6k $1.1m $1.1m 0.02% Reduced -61.7k -61,722
70 NEOS Investment Management LLC 0.04% of their portfolio Westport, CT 39,75439.8k $932.6k $932.6k 0.04% Added +8.2k +8,225
71 MetLife Investment Management, LLC 0.01% of their portfolio Whippany, NJ 39,24339.2k $920.6k $920.6k 0.01% Added +7.0k +7,003
72 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 36,47336.5k $855.7k $855.7k 0.00% First filing
73 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 35,46935.5k $831.8k $831.8k 0.00% First filing
74 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 35,43735.4k $831.4k $831.4k 0.00% Reduced -68.7k -68,683
75 TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio STAMFORD, CT 34,31934.3k $805.1k $805.1k 0.01% Reduced -1.9k -1,876
76 GUGGENHEIM CAPITAL LLC 0.01% of their portfolio CHICAGO, IL 31,90331.9k $748.4k $748.4k 0.01% Added +6.9k +6,866
77 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 30,95431.0k $726.2k $726.2k 0.00% Reduced -1.8k -1,827
78 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 30,07830.1k $705.6k $705.6k 0.00% Reduced -4.7k -4,660
79 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 29,45129.5k $690.9k $690.9k 0.00% Added +9.3k +9,325
80 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 29,26929.3k $686.7k $686.7k 0.00% Reduced -226.2k -226,165
81 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 29,07229.1k $682.0k $682.0k 0.00% Reduced -30.2k -30,222
82 TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.01% of their portfolio FRANKFORT, KY 28,52128.5k $669.0k $669.0k 0.01% Unchanged
83 ADAR1 Capital Management, LLC 0.12% of their portfolio AUSTIN, TX 25,50725.5k $598.4k $598.4k 0.12% Added +23.7k +23,700
84 Chicago Partners Investment Group LLC 0.03% of their portfolio CHICAGO, IL 25,20025.2k $670.6k $670.6k 0.03% Unchanged
85 Trexquant Investment LP 0.01% of their portfolio STAMFORD, CT 24,65124.7k $578.3k $578.3k 0.01% New
86 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 24,10024.1k $565.4k $565.4k 0.00% New
87 Walleye Capital LLC 0.01% of their portfolio NEW YORK, NY 23,70723.7k $556.2k $556.2k 0.01% Added +12.6k +12,627
88 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 22,87622.9k $537.0k $537.0k 0.00% Added +5.4k +5,410
89 PROFUND ADVISORS LLC 0.02% of their portfolio BETHESDA, MD 22,83822.8k $535.8k $535.8k 0.02% Reduced -23.0k -23,032
90 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 22,60422.6k $530.3k $530.3k 0.00% Added +2.9k +2,911
91 Atom Investors LP 0.05% of their portfolio AUSTIN, TX 21,05021.1k $493.8k $493.8k 0.05% Added +6.3k +6,278
92 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 20,00020.0k $466.0k $466.0k 0.00% Unchanged
93 QUATTRO FINANCIAL ADVISORS LLC 0.12% of their portfolio The Woodlands, TX 20,00020.0k $469.2k $469.2k 0.12% Added +10.0k +10,000
94 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 18,16218.2k $426.1k $426.1k 0.00% Reduced -27.3k -27,274
95 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 18,10018.1k $424.6k $424.6k 0.00% New
96 Handelsbanken Fonder AB 0.00% of their portfolio STOCKHOLM, V7 17,80017.8k $418.0k $418.0k 0.00% Added +8.0k +8,000
97 CAPITAL FUND MANAGEMENT S.A. 0.00% of their portfolio PARIS, I0 17,61917.6k $413.3k $413.3k 0.00% Reduced -3.7k -3,704
98 LMR Partners LLP 0.01% of their portfolio LONDON, X0 17,60017.6k $412.9k $412.9k 0.01% Unchanged
99 Headlands Technologies LLC 0.04% of their portfolio CHICAGO, IL 17,00317.0k $398.9k $398.9k 0.04% Added +12.8k +12,786
100 Tower Research Capital LLC (TRC) 0.01% of their portfolio NEW YORK, NY 15,64215.6k $367.0k $367.0k 0.01% Added +14.8k +14,758