Vault-13

AEROVATE THERAPEUTICS INC

COM · CUSIP 008064107

61 institutional holders -6 vs Q1 2023
28,473,06628.5m shares reported held*
$488.3mreported value*
3 new 23 added 15 reduced 9 sold out net bought ≈ $32.8m (+1.9m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $17.15.

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0255075Q3 22: 56Q4 22: 71Q1 23: 67Q2 23: 6161Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 202256
Q4 202271
Q1 202367
Q2 202361

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q4 22: 38 bought or addedQ4 22: 32 cut or sold outQ4 22Q1 23: 29 bought or addedQ1 23: 34 cut or sold outQ1 23Q2 23: 26 bought or addedQ2 23: 24 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 20223832
Q1 20232934
Q2 20232624

Biggest buyers

Driehaus Capital Management LLC New +1,194,091+1.2m
TCG Crossover Management, LLC Added +1,120,000+1.1m
Frazier Life Sciences Management, L.P. Added +656,748+656.7k
CITADEL ADVISORS LLC New +291,938+291.9k
GREAT POINT PARTNERS LLC Added +176,538+176.5k
HighVista Strategies LLC Added +25,970+26.0k
BlackRock Inc. Added +22,648+22.6k
TWO SIGMA INVESTMENTS, LP Added +18,502+18.5k
GEODE CAPITAL MANAGEMENT, LLC Added +15,559+15.6k
DIMENSIONAL FUND ADVISORS LP Added +13,397+13.4k

Biggest sellers

Venrock Adviser, LLC Sold out -833,927-833.9k
FMR LLC Reduced -414,316-414.3k
Ikarian Capital, LLC Sold out -195,146-195.1k
Point72 Asset Management, L.P. Sold out -69,119-69.1k
FRED ALGER MANAGEMENT, LLC Reduced -46,174-46.2k
BOOTHBAY FUND MANAGEMENT, LLC Sold out -39,573-39.6k
RENAISSANCE TECHNOLOGIES LLC Sold out -17,600-17.6k
D. E. Shaw & Co., Inc. Sold out -15,958-16.0k
Trustees of Columbia University in the City of New York Sold out -13,190-13.2k
MORGAN STANLEY Reduced -11,948-11.9k

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 RA CAPITAL MANAGEMENT, L.P. 2.68% of their portfolio BOSTON, MA 8,263,9828.3m $141.7m $141.7m 2.68% Unchanged
2 Sofinnova Investments, Inc. 4.26% of their portfolio Menlo Park, CA 3,758,6863.8m $64.5m $64.5m 4.26% Unchanged
3 TCG Crossover Management, LLC 6.19% of their portfolio PALO ALTO, CA 2,201,2742.2m $37.8m $37.8m 6.19% Added +1.1m +1,120,000
4 Atlas Venture Life Science Advisors, LLC 4.35% of their portfolio CAMBRIDGE, MA 2,039,2492.0m $35.0m $35.0m 4.35% Unchanged
5 BAKER BROS. ADVISORS LP 0.19% of their portfolio NEW YORK, NY 1,963,4792.0m $33.7m $33.7m 0.19% Unchanged
6 Cormorant Asset Management, LP 1.53% of their portfolio BOSTON, MA 1,561,6961.6m $26.8m $26.8m 1.53% Unchanged
7 Driehaus Capital Management LLC 0.26% of their portfolio Chicago, IL 1,194,0911.2m $20.5m $20.5m 0.26% New
8 Frazier Life Sciences Management, L.P. 1.02% of their portfolio PALO ALTO, CA 994,858994.9k $17.1m $17.1m 1.02% Added +656.7k +656,748
9 GREAT POINT PARTNERS LLC 3.20% of their portfolio Greenwich, CT 932,158932.2k $16.0m $16.0m 3.20% Added +176.5k +176,538
10 ORBIMED ADVISORS LLC 0.24% of their portfolio New York, NY 756,930756.9k $13.0m $13.0m 0.24% Unchanged
11 FMR LLC 0.00% of their portfolio BOSTON, MA 727,614727.6k $12.5m $12.5m 0.00% Reduced -414.3k -414,316
12 BlackRock Inc. 0.00% of their portfolio New York, NY 622,647622.6k $10.7m $10.7m 0.00% Added +22.6k +22,648
13 Octagon Capital Advisors LP 1.49% of their portfolio NEW YORK, NY 621,712621.7k $10.7m $10.7m 1.49% Unchanged
14 OUP Management Co., LLC 17.66% of their portfolio Bala Cynwyd, PA 603,762603.8k $10.4m $10.4m 17.66% Unchanged
15 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 523,567523.6k $9.0m $9.0m 0.00% Added +10.3k +10,255
16 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 291,938291.9k $5.0m $5.0m 0.01% New
17 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 203,058203.1k $3.5m $3.5m 0.00% Added +15.6k +15,559
18 Ghost Tree Capital, LLC 1.25% of their portfolio NEW YORK, NY 201,197201.2k $3.5m $3.5m 1.25% Added +1.2k +1,197
19 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 188,874188.9k $3.2m $3.2m 0.00% Added +4.3k +4,281
20 Nantahala Capital Management, LLC 0.20% of their portfolio NEW CANAAN, CT 95,00095.0k $1.6m $1.6m 0.20% Unchanged
21 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 87,99788.0k $1.5m $1.5m 0.00% Added +10.6k +10,558
22 FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio NEW YORK, NY 57,87457.9k $992.5k $992.5k 0.01% Reduced -46.2k -46,174
23 Skandinaviska Enskilda Banken AB (publ) 0.01% of their portfolio STOCKHOLM, V7 50,86650.9k $872.0k $872.0k 0.01% Unchanged
24 Eversept Partners, LP 0.09% of their portfolio NEW YORK, NY 50,24250.2k $861.6k $861.6k 0.09% Unchanged
25 Nan Fung Group Holdings Ltd 0.53% of their portfolio KAI TAK, K3 47,93647.9k $822.1k $822.1k 0.53% Unchanged
26 HighVista Strategies LLC 0.33% of their portfolio BOSTON, MA 41,80341.8k $716.9k $716.9k 0.33% Added +26.0k +25,970
27 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 36,31036.3k $622.7k $622.7k 0.00% Unchanged
28 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 33,38733.4k $572.6k $572.6k 0.00% Added +12.6k +12,595
29 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 33,02633.0k $566.4k $566.4k 0.00% Reduced -11.9k -11,948
30 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 30,01130.0k $514.7k $514.7k 0.00% Added +18.5k +18,502
31 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 27,23227.2k $467.0k $467.0k 0.00% Reduced -563 -563
32 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 26,67326.7k $457.4k $457.4k 0.00% Added +2.0k +2,032
33 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 25,01125.0k $428.4k $428.4k 0.00% Added +13.4k +13,397
34 Parkwood LLC 0.07% of their portfolio CLEVELAND, OH 22,83222.8k $392.0k $392.0k 0.07% Reduced -3.0k -3,031
35 ALPS ADVISORS INC 0.00% of their portfolio Denver, CO 18,32018.3k $314.2k $314.2k 0.00% Added +2.1k +2,112
36 Swiss National Bank 0.00% of their portfolio ZURICH, V8 16,20116.2k $277.8k $277.8k 0.00% Reduced -2.4k -2,400
37 Ensign Peak Advisors, Inc 0.00% of their portfolio SALT LAKE CITY, UT 15,00015.0k $257.2k $257.2k 0.00% Unchanged
38 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 12,98613.0k $222.7k $222.7k 0.00% Reduced -1.8k -1,812
39 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 11,72011.7k $201.0k $201.0k 0.00% New
40 Ascentis Independent Advisors 0.05% of their portfolio DALLAS, TX 10,53010.5k $180.6k $180.6k 0.05% Unchanged
41 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 9,8969.9k $169.7k $169.7k 0.00% Reduced -1.1k -1,063
42 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 8,0708.1k $138.4k $138.4k 0.00% Added +986 +986
43 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 6,2966.3k $108.0k $108.0k 0.00% Reduced -7.0k -7,006
44 Legal & General Group Plc 0.00% of their portfolio London, X0 5,7745.8k $99.0k $99.0k 0.00% Added +2.3k +2,343
45 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 5,2285.2k $89.7k $89.7k 0.00% Unchanged
46 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 4,9855.0k $85.5k $85.5k 0.00% Reduced -654 -654
47 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 4,8444.8k $83.1k $83.1k 0.00% Added +412 +412
48 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 4,2734.3k $73.3k $73.3k 0.00% Reduced -3.4k -3,411
49 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 4,2004.2k $72.0k $72.0k 0.00% Added +2.6k +2,564
50 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 3,4063.4k $58.4k $58.4k 0.00% Reduced -1.3k -1,314
51 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 3,3243.3k $57.0k $57.0k 0.00% Added +3.1k +3,095
52 UBS Group AG 0.00% of their portfolio ZURICH, V8 2,9993.0k $51.4k $51.4k 0.00% Reduced -3.0k -2,987
53 STRS OHIO 0.00% of their portfolio COLUMBUS, OH 2,3002.3k $39.0k $39.0k 0.00% Reduced -2.3k -2,300
54 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 1,5351.5k $26.0k $26.0k 0.00% Added +548 +548
55 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 939939 $16.1k $16.1k 0.00% Unchanged
56 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 908908 $15.6k $15.6k 0.00% Reduced -1.8k -1,794
57 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 880880 $15.0k $15.0k 0.00% Added +365 +365
58 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 772772 $13.2k $13.2k 0.00% Unchanged
59 Metropolitan Life Insurance Co/NY 0.00% of their portfolio New York, NY 701701 $12.0k $12.0k 0.00% Unchanged
60 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 77 $120 $120 0.00% Added +3 +3
61 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged