ACADIA PHARMACEUTICALS INC ACAD
COM · Common Stock · CUSIP 004225108 · ISIN US0042251084
Pharmaceutical company, which developed Nuplazid, based in San Diego, California.
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- Founded1993
- Websiteacadia-pharm.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.4m this quarter). Holder counts are more reliable. Shares outstanding: 161.9m as of 2022-10-21, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $16.36. Options: 11 managers hold calls ($11.2m notional), 10 hold puts ($7.4m).
Biggest calls
| GROUP ONE TRADING LLC | — | $4.3m265.5k shares |
| CITADEL ADVISORS LLC | — | $2.4m148.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $1.7m105.3k shares |
| SIMPLEX TRADING, LLC | — | $939.0k57.4k shares |
| Caption Management, LLC | — | $738.0k45.0k shares |
| JANE STREET GROUP, LLC | — | $530.0k32.4k shares |
| WOLVERINE TRADING, LLC | — | $345.0k21.4k shares |
| Walleye Capital LLC | — | $165.0k10.1k shares |
| Cutler Group LLC / CA | — | $28.0k26.2k shares |
| Walleye Trading LLC | — | $5.0k300 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $1.8m112.6k shares |
| SIMPLEX TRADING, LLC | — | $1.6m100.7k shares |
| JANE STREET GROUP, LLC | — | $1.5m94.0k shares |
| CITADEL ADVISORS LLC | — | $1.1m70.0k shares |
| Caption Management, LLC | — | $738.0k45.0k shares |
| GROUP ONE TRADING LLC | — | $288.0k17.6k shares |
| Walleye Trading LLC | — | $133.0k8.1k shares |
| Walleye Capital LLC | — | $82.0k5.0k shares |
| Cutler Group LLC / CA | — | $1.0k1.5k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BAKER BROS. ADVISORS LP 13D · may seek influence filed 2026-02-26 | 25.4% |
| BlackRock, Inc. 13G · institution filed 2025-02-07 | 11.9% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.3% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-28 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q3 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2020 | 0 | — | 0 | — | — |
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 2 | $128.2k | — |
| Q1 2022 | 0 | — | 6 | $336.7k | — |
| Q2 2022 | 0 | — | 6 | $217.5k | — |
| Q3 2022 | 0 | — | 0 | — | — |
None reported in Q3 2022.
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 4.49% of their portfolio | 41.9m $685.9m | — |
| VANGUARD GROUP INC 0.01% of their portfolio | 12.9m $211.5m | — |
| FMR LLC 0.02% of their portfolio | 11.6m $189.3m | — |
| BlackRock Inc. 0.01% of their portfolio | 10.0m $163.2m | — |
| STATE STREET CORP 0.01% of their portfolio | 6.8m $110.9m | — |
| EcoR1 Capital, LLC 2.89% of their portfolio | 6.0m $98.0m | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 4.9m $80.0m | — |
| D. E. Shaw & Co., Inc. 0.14% of their portfolio | 4.7m $77.1m | — |
| RTW INVESTMENTS, LP 1.38% of their portfolio | 3.7m $60.1m | — |
| MORGAN STANLEY 0.01% of their portfolio | 3.1m $50.2m | — |
| FIRST TRUST ADVISORS LP 0.06% of their portfolio | 2.9m $47.8m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 2.2m $36.3m | — |
| NORGES BANK 0.01% of their portfolio | 2.0m $32.3m | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.9m $30.4m | — |
| WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio | 1.7m $28.0m | — |
| Palo Alto Investors LP 2.17% of their portfolio | 1.7m $27.5m | — |
| FRED ALGER MANAGEMENT, LLC 0.13% of their portfolio | 1.5m $25.1m | — |
| EMERALD ADVISERS, LLC 1.12% of their portfolio | 1.3m $21.8m | — |
| Boxer Capital, LLC 1.16% of their portfolio | 1.3m $20.7m | — |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 1.2m $19.3m | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.1m $18.3m | — |
| Finepoint Capital LP 5.98% of their portfolio | 1.1m $18.2m | — |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.14% of their portfolio | 1.1m $17.8m | — |
| EMERALD MUTUAL FUND ADVISERS TRUST 1.07% of their portfolio | 1.0m $16.9m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 952.7k $15.6m | — |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 929.8k $15.2m | — |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 929.0k $15.2m | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 916.4k $15.0m | — |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.07% of their portfolio | 875.3k $14.3m | — |
| Frazier Life Sciences Management, L.P. 1.08% of their portfolio | 857.3k $14.0m | — |
| Fairmount Funds Management LLC 2.27% of their portfolio | 751.8k $12.3m | — |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.06% of their portfolio | 704.6k $11.5m | — |
| PANAGORA ASSET MANAGEMENT INC 0.07% of their portfolio | 657.4k $10.8m | — |
| NORDEA INVESTMENT MANAGEMENT AB 0.02% of their portfolio | 625.6k $10.2m | — |
| Bain Capital Life Sciences Investors, LLC 1.19% of their portfolio | 610.5k $10.0m | — |
| Bank of New York Mellon Corp 0.00% of their portfolio | 531.5k $8.7m | — |
| RICE HALL JAMES & ASSOCIATES, LLC 0.50% of their portfolio | 523.9k $8.6m | — |
| Connor, Clark & Lunn Investment Management Ltd. 0.05% of their portfolio | 509.9k $8.3m | — |
| Polar Capital Holdings Plc 0.05% of their portfolio | 500.0k $8.2m | — |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.09% of their portfolio | 484.6k $7.9m | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 484.3k $7.9m | — |
| Invesco Ltd. 0.00% of their portfolio | 480.9k $7.9m | — |
| Squarepoint Ops LLC 0.07% of their portfolio | 475.9k $7.8m | — |
| Rockefeller Capital Management L.P. 0.04% of their portfolio | 458.8k $7.5m | — |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 409.3k $6.7m | — |
| Rafferty Asset Management, LLC 0.07% of their portfolio | 398.7k $6.5m | — |
| Woodline Partners LP 0.10% of their portfolio | 395.5k $6.5m | — |
| CITIGROUP INC 0.01% of their portfolio | 378.7k $6.2m | — |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 368.7k $6.0m | — |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 356.4k $5.8m | — |
| Ikarian Capital, LLC 2.65% of their portfolio | 325.0k $5.3m | — |
| Swiss National Bank 0.00% of their portfolio | 287.1k $4.7m | — |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 282.2k $5.0m | — |
| CAPITAL FUND MANAGEMENT S.A. 0.11% of their portfolio | 263.1k $4.3m | — |
| Ergoteles LLC 0.15% of their portfolio | 258.3k $4.2m | — |
| Birchview Capital, LP 2.87% of their portfolio | 249.4k $4.1m | — |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 248.8k $4.1m | — |
| PICTET ASSET MANAGEMENT SA 0.01% of their portfolio | 222.6k $3.6m | — |
| Walleye Capital LLC 0.08% of their portfolio | 209.5k $3.4m | — |
| Hennion & Walsh Asset Management, Inc. 0.22% of their portfolio | 200.0k $3.3m | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 191.6k $3.1m | — |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 189.5k $3.1m | — |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 188.2k $3.1m | — |
| Empire Life Investments Inc. 0.22% of their portfolio | 177.9k $2.9m | — |
| ALGERT GLOBAL LLC 0.18% of their portfolio | 177.7k $2.9m | — |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 177.6k $2.9m | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 177.4k $2.9m | — |
| Hudson Bay Capital Management LP 0.03% of their portfolio | 175.0k $2.9m | — |
| Thrivent Financial for Lutherans 0.01% of their portfolio | 169.5k $2.8m | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 167.6k $2.7m | — |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 163.0k $2.7m | — |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 152.2k $2.5m | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 151.7k $2.5m | — |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 145.2k $2.4m | — |
| TD Asset Management Inc 0.00% of their portfolio | 126.7k $2.0m | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 123.4k $2.0m | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 123.2k $2.0m | — |
| DUALITY ADVISERS, LP 0.20% of their portfolio | 112.2k $1.8m | — |
| Legal & General Group Plc 0.00% of their portfolio | 111.7k $1.8m | — |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 103.2k $1.7m | — |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 102.8k $1.7m | — |
| Erste Asset Management GmbH 0.03% of their portfolio | 90.6k $1.5m | — |
| ALPS ADVISORS INC 0.01% of their portfolio | 88.4k $1.4m | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 85.8k $1.4m | — |
| JUPITER ASSET MANAGEMENT LTD 0.02% of their portfolio | 77.3k $1.3m | — |
| Duquesne Family Office LLC 0.07% of their portfolio | 74.4k $1.2m | — |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 72.7k $1.2m | — |
| Tekla Capital Management LLC 0.05% of their portfolio | 72.2k $1.2m | — |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio | 70.9k $1.2m | — |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 70.3k $1.2m | — |
| Skandinaviska Enskilda Banken AB (publ) 0.01% of their portfolio | 67.1k $1.1m | — |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 66.7k $1.1m | — |
| NOMURA HOLDINGS INC 0.01% of their portfolio | 66.5k $1.1m | — |
| MetLife Investment Management, LLC 0.01% of their portfolio | 66.4k $1.1m | — |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 66.1k $1.1m | — |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 61.0k $998.0k | — |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 59.9k $980.0k | — |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 58.7k $960.0k | — |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 58.1k $951.0k | — |
| STRS OHIO 0.00% of their portfolio | 57.6k $942.0k | — |