Vault-13

MERUS N V MRUS

COM · Common Stock · CUSIP N5749R100

187 institutional holders -7 vs Q4 2024
70,914,94170.9m shares reported held*
$3.0bnreported value*
24 new 72 added 62 reduced 29 sold out net bought ≈ $32.2m (+764.2k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $42.11. Options: 9 managers hold calls ($17.1m notional), 7 hold puts ($4.1m).

Trends to Q1 2025

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 101Q4 22: 92Q1 23: 105Q2 23: 115Q3 23: 114Q4 23: 133Q1 24: 158Q2 24: 181Q3 24: 191Q4 24: 194Q1 25: 187187Q3 22Q1 23Q3 23Q1 24Q3 24Q1 25
Numbers
QuarterHolders
Q3 2022101
Q4 202292
Q1 2023105
Q2 2023115
Q3 2023114
Q4 2023133
Q1 2024158
Q2 2024181
Q3 2024191
Q4 2024194
Q1 2025187

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q2 23: 59 bought or addedQ2 23: 48 cut or sold outQ3 23: 60 bought or addedQ3 23: 45 cut or sold outQ3 23Q4 23: 68 bought or addedQ4 23: 53 cut or sold outQ1 24: 85 bought or addedQ1 24: 62 cut or sold outQ1 24Q2 24: 119 bought or addedQ2 24: 68 cut or sold outQ3 24: 105 bought or addedQ3 24: 68 cut or sold outQ3 24Q4 24: 96 bought or addedQ4 24: 86 cut or sold outQ1 25: 96 bought or addedQ1 25: 91 cut or sold outQ1 25
Numbers
QuarterBought or addedCut or sold out
Q2 20235948
Q3 20236045
Q4 20236853
Q1 20248562
Q2 202411968
Q3 202410568
Q4 20249686
Q1 20259691

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20m$40m$60mQ2 24 calls: $41.4mQ2 24 puts: $15.5mQ2 24P/C 0.37Q3 24 calls: $12.2mQ3 24 puts: $15.3mQ3 24P/C 1.26Q4 24 calls: $5.1mQ4 24 puts: $3.7mQ4 24P/C 0.74Q1 25 calls: $17.1mQ1 25 puts: $4.1mQ1 25P/C 0.24
Numbers
QuarterCallsPutsP/C
Q2 2024$41.4m$15.5m0.37
Q3 2024$12.2m$15.3m1.26
Q4 2024$5.1m$3.7m0.74
Q1 2025$17.1m$4.1m0.24

Biggest buyers

Paradigm Biocapital Advisors LP Added +1,679,777+1.7m
WELLINGTON MANAGEMENT GROUP LLP Added +1,220,519+1.2m
Avoro Capital Advisors LLC Added +875,000+875.0k
Commodore Capital LP Added +598,658+598.7k
WESTFIELD CAPITAL MANAGEMENT CO LP Added +508,063+508.1k
PERCEPTIVE ADVISORS LLC Added +390,485+390.5k
JANUS HENDERSON GROUP PLC Added +360,521+360.5k
JPMORGAN CHASE & CO Added +269,943+269.9k
Siren, L.L.C. Added +259,055+259.1k
MORGAN STANLEY Added +228,388+228.4k

Biggest sellers

Boxer Capital Management, LLC Reduced -1,200,000-1.2m
Logos Global Management LP Sold out -750,000-750.0k
MARSHALL WACE, LLP Reduced -602,315-602.3k
Venrock Adviser, LLC Sold out -592,411-592.4k
FEDERATED HERMES, INC. Reduced -548,750-548.8k
D. E. Shaw & Co., Inc. Reduced -308,031-308.0k
T. Rowe Price Investment Management, Inc. Reduced -298,815-298.8k
MILLENNIUM MANAGEMENT LLC Reduced -297,131-297.1k
SAMLYN CAPITAL, LLC Reduced -288,750-288.8k
STEMPOINT CAPITAL LP Reduced -268,056-268.1k

Biggest calls

Caption Management, LLC Added $11.4m270.0k shares
BARCLAYS PLC Reduced $1.6m38.6k shares
CITIGROUP INC New $1.3m30.0k shares
GROUP ONE TRADING LLC New $1.1m25.5k shares
Kazazian Asset Management, LLC Added $610.3k14.5k shares
CITADEL ADVISORS LLC Added $454.6k10.8k shares
SIMPLEX TRADING, LLC Added $446.0k10.6k shares
JANE STREET GROUP, LLC Reduced $231.5k5.5k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITIGROUP INC New $1.3m30.0k shares
Caption Management, LLC Unchanged $1.3m30.0k shares
JANE STREET GROUP, LLC Added $1.1m26.8k shares
CITADEL ADVISORS LLC Reduced $408.3k9.7k shares
GROUP ONE TRADING LLC New $42.1k1.0k shares
SIMPLEX TRADING, LLC Reduced $25.0k600 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

No one currently above 5% in the filings since 19 Dec 2024.

Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (0.0%, 2026-02-17), GENMAB A/S (0.0%, 2025-12-30), RTW INVESTMENTS, LP (2.7%, 2025-11-14)

Holders, Q1 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.02% of their portfolio BOSTON, MA 6,966,9147.0m $293.2m $293.2m 0.02% Added +67.4k +67,393
2 WELLINGTON MANAGEMENT GROUP LLP 0.04% of their portfolio Boston, MA 4,718,1724.7m $198.6m $198.6m 0.04% Added +1.2m +1,220,519
3 Commodore Capital LP 13.87% of their portfolio NEW YORK, NY 4,472,8404.5m $188.3m $188.3m 13.87% Added +598.7k +598,658
4 RTW INVESTMENTS, LP 2.68% of their portfolio NEW YORK, NY 4,169,3934.2m $175.5m $175.5m 2.68% Unchanged
5 Paradigm Biocapital Advisors LP 6.53% of their portfolio NEW YORK, NY 3,369,6993.4m $141.8m $141.8m 6.53% Added +1.7m +1,679,777
6 DEERFIELD MANAGEMENT COMPANY, L.P. 2.65% of their portfolio New York, NY 3,173,9283.2m $133.6m $133.6m 2.65% Added +201.1k +201,141
7 Avoro Capital Advisors LLC 1.97% of their portfolio NEW YORK, NY 3,000,0003.0m $126.3m $126.3m 1.97% Added +875.0k +875,000
8 SAMLYN CAPITAL, LLC 1.65% of their portfolio New York, NY 2,379,4282.4m $100.2m $100.2m 1.65% Reduced -288.8k -288,750
9 FRANKLIN RESOURCES INC 0.02% of their portfolio San Mateo, CA 1,991,1932.0m $83.8m $83.8m 0.02% Added +6.7k +6,655
10 Holocene Advisors, LP 0.23% of their portfolio New York, NY 1,873,6251.9m $78.9m $78.9m 0.23% Reduced -6.4k -6,393
11 Polar Capital Holdings Plc 0.44% of their portfolio London, X0 1,706,8621.7m $71.8m $71.8m 0.44% Added +624 +624
12 BlackRock, Inc. 0.00% of their portfolio New York, NY 1,691,8691.7m $71.2m $71.2m 0.00% Added +104.7k +104,708
13 Lynx1 Capital Management LP 23.65% of their portfolio DORADO, PR 1,568,8411.6m $66.0m $66.0m 23.65% Reduced -12.0k -12,000
14 WESTFIELD CAPITAL MANAGEMENT CO LP 0.31% of their portfolio BOSTON, MA 1,501,2201.5m $63.2m $63.2m 0.31% Added +508.1k +508,063
15 Woodline Partners LP 0.38% of their portfolio San Francisco, CA 1,400,1711.4m $58.9m $58.9m 0.38% Added +211.7k +211,653
16 Driehaus Capital Management LLC 0.51% of their portfolio Chicago, IL 1,254,1491.3m $52.8m $52.8m 0.51% Reduced -26.2k -26,188
17 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 1,095,7421.1m $46.1m $46.1m 0.01% Reduced -21.1k -21,078
18 FEDERATED HERMES, INC. 0.09% of their portfolio PITTSBURGH, PA 1,044,6251.0m $44.0m $44.0m 0.09% Reduced -548.8k -548,750
19 Siren, L.L.C. 2.48% of their portfolio New York, NY 1,043,4671.0m $43.9m $43.9m 2.48% Added +259.1k +259,055
20 Pictet Asset Management Holding SA 0.05% of their portfolio CAROUGE, V8 1,032,1011.0m $43.4m $43.4m 0.05% Added +274 +274
21 Rock Springs Capital Management LP 2.36% of their portfolio Baltimore, MD 980,751980.8k $41.3m $41.3m 2.36% Added +88.2k +88,202
22 UBS Group AG 0.01% of their portfolio ZURICH, V8 862,748862.7k $36.3m $36.3m 0.01% Reduced -244.7k -244,690
23 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 828,217828.2k $34.9m $34.9m 0.01% Added +41.9k +41,852
24 SILVERARC CAPITAL MANAGEMENT, LLC 7.13% of their portfolio BOSTON, MA 811,021811.0k $34.1m $34.1m 7.13% Added +130.2k +130,176
25 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 803,588803.6k $33.8m $33.8m 0.00% Added +228.4k +228,388
26 NOVO HOLDINGS A/S 2.53% of their portfolio HELLERUP, G7 789,129789.1k $33.2m $33.2m 2.53% Added +39.1k +39,129
27 Cormorant Asset Management, LP 2.36% of their portfolio BOSTON, MA 740,000740.0k $31.1m $31.1m 2.36% Unchanged
28 ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio NASHVILLE, TN 739,288739.3k $31.1m $31.1m 0.01% Reduced -57.7k -57,669
29 Boxer Capital Management, LLC 8.86% of their portfolio San Diego, CA 700,000700.0k $29.5m $29.5m 8.86% Reduced -1.2m -1,200,000
30 PERCEPTIVE ADVISORS LLC 1.03% of their portfolio NEW YORK, NY 690,485690.5k $29.1m $29.1m 1.03% Added +390.5k +390,485
31 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 586,434586.4k $24.7m $24.7m 0.02% Reduced -297.1k -297,131
32 TWO SIGMA ADVISERS, LP 0.05% of their portfolio NEW YORK, NY 554,400554.4k $23.3m $23.3m 0.05% Reduced -166.4k -166,400
33 T. Rowe Price Investment Management, Inc. 0.01% of their portfolio BALTIMORE, MD 509,761509.8k $21.5m $21.5m 0.01% Reduced -298.8k -298,815
34 First Turn Management, LLC 3.94% of their portfolio DEL MAR, CA 463,960464.0k $19.5m $19.5m 3.94% Added +178.8k +178,801
35 DAFNA Capital Management LLC 5.51% of their portfolio LOS ANGELES, CA 461,804461.8k $19.4m $19.4m 5.51% Added +10.0k +10,000
36 GILEAD SCIENCES, INC. 1.61% of their portfolio FOSTER CITY, CA 452,527452.5k $19.0m $19.0m 1.61% Unchanged
37 Artia Global Partners LP 5.24% of their portfolio MIAMI, FL 424,640424.6k $17.9m $17.9m 5.24% Reduced -39.2k -39,200
38 Soleus Capital Management, L.P. 1.27% of their portfolio GREENWICH, CT 385,821385.8k $16.2m $16.2m 1.27% Added +73.5k +73,500
39 JANUS HENDERSON GROUP PLC 0.01% of their portfolio LONDON, X0 381,811381.8k $17.0m $17.0m 0.01% Added +360.5k +360,521
40 Caligan Partners LP 3.31% of their portfolio NEW YORK, NY 376,954377.0k $15.9m $15.9m 3.31% Added +122.0k +121,954
41 Frazier Life Sciences Management, L.P. 0.72% of their portfolio PALO ALTO, CA 373,100373.1k $15.7m $15.7m 0.72% Unchanged
42 STEMPOINT CAPITAL LP 4.66% of their portfolio NEW YORK, NY 346,756346.8k $14.6m $14.6m 4.66% Reduced -268.1k -268,056
43 TimesSquare Capital Management, LLC 0.23% of their portfolio NEW YORK, NY 343,705343.7k $14.5m $14.5m 0.23% Added +12.5k +12,510
44 TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio NEW YORK, NY 325,861325.9k $13.7m $13.7m 0.03% Reduced -181.9k -181,880
45 Saturn V Capital Management LP 6.87% of their portfolio AUSTIN, TX 323,211323.2k $13.6m $13.6m 6.87% Added +88.6k +88,574
46 Affinity Asset Advisors, LLC 2.12% of their portfolio NEW YORK, NY 321,962322.0k $13.6m $13.6m 2.12% Reduced -67.3k -67,279
47 Octagon Capital Advisors LP 2.55% of their portfolio NEW YORK, NY 308,000308.0k $13.0m $13.0m 2.55% Unchanged
48 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 295,123295.1k $12.4m $12.4m 0.00% Added +269.9k +269,943
49 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 259,790259.8k $10.9m $10.9m 0.00% Reduced -1.8k -1,838
50 MARSHALL WACE, LLP 0.01% of their portfolio LONDON, X0 259,774259.8k $10.9m $10.9m 0.01% Reduced -602.3k -602,315
51 GREAT POINT PARTNERS LLC 5.43% of their portfolio Greenwich, CT 237,156237.2k $10.0m $10.0m 5.43% Added +79.1k +79,064
52 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 232,750232.8k $9.8m $9.8m 0.00% Added +11.2k +11,232
53 BAKER BROS. ADVISORS LP 0.10% of their portfolio NEW YORK, NY 223,500223.5k $9.4m $9.4m 0.10% Reduced -226.5k -226,500
54 Decheng Capital LLC 2.23% of their portfolio MENLO PARK, CA 189,098189.1k $8.0m $8.0m 2.23% Unchanged
55 Impax Asset Management Group plc 0.05% of their portfolio LONDON, X0 180,000180.0k $7.6m $7.6m 0.05% Unchanged
56 Aberdeen Group plc 0.01% of their portfolio EDINBURGH, X0 172,063172.1k $7.2m $7.2m 0.01% Added +84.8k +84,848
57 BOOTHBAY FUND MANAGEMENT, LLC 0.23% of their portfolio NEW YORK, NY 160,000160.0k $6.7m $6.7m 0.23% Added +80.0k +80,000
58 STATE OF WISCONSIN INVESTMENT BOARD 0.02% of their portfolio MADISON, WI 158,308158.3k $6.7m $6.7m 0.02% Added +443 +443
59 Tri Locum Partners LP 3.39% of their portfolio NEW YORK, NY 156,915156.9k $6.6m $6.6m 3.39% Reduced -190.4k -190,388
60 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 156,560156.6k $6.6m $6.6m 0.00% Added +94.6k +94,560
61 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 124,795124.8k $5.3m $5.3m 0.00% Reduced -117.4k -117,398
62 Allostery Investments LP 7.57% of their portfolio Stamford, CT 124,657124.7k $5.2m $5.2m 7.57% Added +102.9k +102,922
63 Carmignac Gestion 0.08% of their portfolio PARIS, I0 121,161121.2k $5.1m $5.1m 0.08% New
64 Nan Fung Group Holdings Ltd 4.12% of their portfolio KAI TAK, K3 120,038120.0k $5.1m $5.1m 4.12% Unchanged
65 Atom Investors LP 0.59% of their portfolio AUSTIN, TX 114,158114.2k $4.8m $4.8m 0.59% Added +12.4k +12,401
66 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 113,149113.1k $4.8m $4.8m 0.00% Added +93 +93
67 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 112,522112.5k $4.7m $4.7m 0.00% Added +13.8k +13,778
68 Moody Aldrich Partners LLC 0.95% of their portfolio MARBLEHEAD, MA 108,281108.3k $4.6m $4.6m 0.95% Added +79.3k +79,286
69 ALGERT GLOBAL LLC 0.11% of their portfolio SAN FRANCISCO, CA 107,101107.1k $4.5m $4.5m 0.11% Reduced -66.0k -66,013
70 SPHERA FUNDS MANAGEMENT LTD. 1.11% of their portfolio TEL AVIV, L3 106,532106.5k $4.5m $4.5m 1.11% Reduced -24.0k -24,000
71 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 102,400102.4k $4.3m $4.3m 0.00% New
72 TANG CAPITAL MANAGEMENT LLC 0.23% of their portfolio SAN DIEGO, CA 100,000100.0k $4.2m $4.2m 0.23% Unchanged
73 Granahan Investment Management, LLC 0.20% of their portfolio WALTHAM, MA 95,72095.7k $4.0m $4.0m 0.20% Reduced -8.8k -8,842
74 Swiss National Bank 0.00% of their portfolio ZURICH, V8 92,85492.9k $3.9m $3.9m 0.00% Reduced -1.1k -1,100
75 CenterBook Partners LP 0.24% of their portfolio GREENWICH, CT 91,08891.1k $3.8m $3.8m 0.24% Reduced -51.8k -51,787
76 Ally Bridge Group (NY) LLC 3.19% of their portfolio NEW YORK, NY 77,89677.9k $3.3m $3.3m 3.19% Reduced -38.9k -38,900
77 Rhenman & Partners Asset Management AB 0.36% of their portfolio Stockholm, V7 74,50074.5k $3.1m $3.1m 0.36% Unchanged
78 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 71,25871.3k $3.0m $3.0m 0.00% Reduced -4.0k -3,982
79 Eversept Partners, LP 0.33% of their portfolio NEW YORK, NY 70,32970.3k $3.0m $3.0m 0.33% Added +2.1k +2,071
80 Alyeska Investment Group, L.P. 0.01% of their portfolio CHICAGO, IL 68,18268.2k $2.9m $2.9m 0.01% Reduced -68.2k -68,182
81 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 67,62067.6k $2.8m $2.8m 0.00% Reduced -8.7k -8,715
82 ADAR1 Capital Management, LLC 0.54% of their portfolio AUSTIN, TX 66,96067.0k $2.8m $2.8m 0.54% Reduced -14.5k -14,500
83 AXA S.A. 0.01% of their portfolio PARIS, I0 64,94464.9k $2.7m $2.7m 0.01% New
84 PLATINUM INVESTMENT MANAGEMENT LTD 0.16% of their portfolio SYDNEY AUSTRALIA 2000, C3 64,84164.8k $2.7m $2.7m 0.16% Reduced -4.2k -4,244
85 HARBOR CAPITAL ADVISORS, INC. 0.12% of their portfolio CHICAGO, IL 64,37464.4k $2.7m $2.7m 0.12% Added +21.2k +21,166
86 Trexquant Investment LP 0.03% of their portfolio STAMFORD, CT 62,38262.4k $2.6m $2.6m 0.03% Reduced -38.4k -38,351
87 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 56,00056.0k $2.4m $2.4m 0.00% Unchanged
88 HighVista Strategies LLC 0.89% of their portfolio BOSTON, MA 55,03955.0k $2.3m $2.3m 0.89% Unchanged
89 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 52,68652.7k $2.2m $2.2m 0.00% Added +50 +50
90 Verition Fund Management LLC 0.01% of their portfolio GREENWICH, CT 51,44651.4k $2.2m $2.2m 0.01% Added +3.3k +3,282
91 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 51,02051.0k $2.1m $2.1m 0.01% Reduced -4.3k -4,341
92 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 51,01751.0k $2.1m $2.1m 0.00% Reduced -308.0k -308,031
93 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 49,90649.9k $2.1m $2.1m 0.00% Added +7.8k +7,821
94 FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio NEW YORK, NY 47,95648.0k $2.0m $2.0m 0.01% Added +668 +668
95 GILDER GAGNON HOWE & CO LLC 0.03% of their portfolio New York, NY 45,94245.9k $1.9m $1.9m 0.03% New
96 ExodusPoint Capital Management, LP 0.03% of their portfolio NEW YORK, NY 45,62445.6k $1.9m $1.9m 0.03% New
97 NEOS Investment Management LLC 0.04% of their portfolio Westport, CT 45,55845.6k $1.9m $1.9m 0.04% Added +31.1k +31,067
98 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 44,08544.1k $1.9m $1.9m 0.00% Added +6.3k +6,280
99 Legal & General Group Plc 0.00% of their portfolio London, X0 43,67443.7k $1.8m $1.8m 0.00% Added +916 +916
100 State of New Jersey Common Pension Fund D 0.01% of their portfolio TRENTON, NJ 41,38041.4k $1.7m $1.7m 0.01% Reduced -6.9k -6,888