Vault-13

MERUS N V MRUS

COM · Common Stock · CUSIP N5749R100

194 institutional holders +3 vs Q3 2024
70,370,28670.4m shares reported held*
$3.0bnreported value*
24 new 72 added 54 reduced 32 sold out net sold ≈ $51.1m (-1.2m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($121.4k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $42.05. Options: 8 managers hold calls ($5.1m notional), 7 hold puts ($3.7m).

Trends to Q4 2024

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 101Q4 22: 92Q1 23: 105Q2 23: 115Q3 23: 114Q4 23: 133Q1 24: 158Q2 24: 181Q3 24: 191Q4 24: 194194Q3 22Q1 23Q3 23Q1 24Q3 24Q4 24
Numbers
QuarterHolders
Q3 2022101
Q4 202292
Q1 2023105
Q2 2023115
Q3 2023114
Q4 2023133
Q1 2024158
Q2 2024181
Q3 2024191
Q4 2024194

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q1 23: 55 bought or addedQ1 23: 30 cut or sold outQ2 23: 59 bought or addedQ2 23: 48 cut or sold outQ2 23Q3 23: 60 bought or addedQ3 23: 45 cut or sold outQ4 23: 68 bought or addedQ4 23: 53 cut or sold outQ4 23Q1 24: 85 bought or addedQ1 24: 62 cut or sold outQ2 24: 119 bought or addedQ2 24: 68 cut or sold outQ2 24Q3 24: 105 bought or addedQ3 24: 68 cut or sold outQ4 24: 96 bought or addedQ4 24: 86 cut or sold outQ4 24
Numbers
QuarterBought or addedCut or sold out
Q1 20235530
Q2 20235948
Q3 20236045
Q4 20236853
Q1 20248562
Q2 202411968
Q3 202410568
Q4 20249686

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20m$40m$60mQ1 24 calls: $4.8mQ1 24 puts: $9.9mQ1 24P/C 2.06Q2 24 calls: $41.4mQ2 24 puts: $15.5mQ2 24P/C 0.37Q3 24 calls: $12.2mQ3 24 puts: $15.3mQ3 24P/C 1.26Q4 24 calls: $5.1mQ4 24 puts: $3.7mQ4 24P/C 0.74
Numbers
QuarterCallsPutsP/C
Q1 2024$4.8m$9.9m2.06
Q2 2024$41.4m$15.5m0.37
Q3 2024$12.2m$15.3m1.26
Q4 2024$5.1m$3.7m0.74

Biggest buyers

UBS Group AG Added +1,096,654+1.1m
Avoro Capital Advisors LLC Added +770,000+770.0k
WELLINGTON MANAGEMENT GROUP LLP Added +610,139+610.1k
Commodore Capital LP Added +524,182+524.2k
Polar Capital Holdings Plc Added +439,186+439.2k
MILLENNIUM MANAGEMENT LLC Added +411,184+411.2k
WESTFIELD CAPITAL MANAGEMENT CO LP Added +384,700+384.7k
Artia Global Partners LP Added +383,669+383.7k
Octagon Capital Advisors LP New +308,000+308.0k
Caligan Partners LP New +255,000+255.0k

Biggest sellers

Boxer Capital, LLC Sold out -1,900,000-1.9m
MORGAN STANLEY Reduced -774,619-774.6k
Paradigm Biocapital Advisors LP Reduced -764,995-765.0k
LORD, ABBETT & CO. LLC Sold out -723,988-724.0k
Balyasny Asset Management L.P. Reduced -565,489-565.5k
GOLDMAN SACHS GROUP INC Reduced -498,698-498.7k
DEERFIELD MANAGEMENT COMPANY, L.P. Reduced -435,752-435.8k
FEDERATED HERMES, INC. Reduced -413,425-413.4k
Venrock Adviser, LLC Reduced -315,552-315.6k
D. E. Shaw & Co., Inc. Reduced -304,541-304.5k

Biggest calls

BARCLAYS PLC New $2.5m60.2k shares
Caption Management, LLC New $1.3m30.0k shares
Kazazian Asset Management, LLC First filing $403.7k9.6k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $357.4k8.5k shares
JANE STREET GROUP, LLC Reduced $307.0k7.3k shares
CITADEL ADVISORS LLC Reduced $206.0k4.9k shares
SIMPLEX TRADING, LLC Reduced $33.0k800 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

Caption Management, LLC New $1.3m30.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.1m27.1k shares
CITADEL ADVISORS LLC Reduced $714.9k17.0k shares
JANE STREET GROUP, LLC Reduced $487.8k11.6k shares
JPMORGAN CHASE & CO Reduced $88.3k2.1k shares
SIMPLEX TRADING, LLC Reduced $58.0k1.4k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

No one currently above 5% in the filings since 19 Dec 2024.

Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (0.0%, 2026-02-17), GENMAB A/S (0.0%, 2025-12-30), RTW INVESTMENTS, LP (2.7%, 2025-11-14)

Holders, Q4 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.02% of their portfolio BOSTON, MA 6,899,5216.9m $290.1m $290.1m 0.02% Added +25.6k +25,595
2 RTW INVESTMENTS, LP 2.65% of their portfolio NEW YORK, NY 4,169,3934.2m $175.3m $175.3m 2.65% Unchanged
3 Commodore Capital LP 11.94% of their portfolio NEW YORK, NY 3,874,1823.9m $162.9m $162.9m 11.94% Added +524.2k +524,182
4 WELLINGTON MANAGEMENT GROUP LLP 0.03% of their portfolio Boston, MA 3,497,6533.5m $147.1m $147.1m 0.03% Added +610.1k +610,139
5 DEERFIELD MANAGEMENT COMPANY, L.P. 2.38% of their portfolio New York, NY 2,972,7873.0m $125.0m $125.0m 2.38% Reduced -435.8k -435,752
6 SAMLYN CAPITAL, LLC 1.78% of their portfolio New York, NY 2,668,1782.7m $112.2m $112.2m 1.78% Added +57.8k +57,785
7 Avoro Capital Advisors LLC 1.26% of their portfolio NEW YORK, NY 2,125,0002.1m $89.4m $89.4m 1.26% Added +770.0k +770,000
8 FRANKLIN RESOURCES INC 0.02% of their portfolio San Mateo, CA 1,984,5382.0m $83.4m $83.4m 0.02% Reduced -272.0k -271,966
9 Boxer Capital Management, LLC 6.80% of their portfolio San Diego, CA 1,900,0001.9m $79.9m $79.9m 6.80% First filing
10 Holocene Advisors, LP 0.26% of their portfolio New York, NY 1,880,0181.9m $79.1m $79.1m 0.26% Added +242.0k +242,030
11 Polar Capital Holdings Plc 0.40% of their portfolio London, X0 1,706,2381.7m $71.7m $71.7m 0.40% Added +439.2k +439,186
12 Paradigm Biocapital Advisors LP 2.47% of their portfolio NEW YORK, NY 1,689,9221.7m $71.1m $71.1m 2.47% Reduced -765.0k -764,995
13 FEDERATED HERMES, INC. 0.15% of their portfolio PITTSBURGH, PA 1,593,3751.6m $67.0m $67.0m 0.15% Reduced -413.4k -413,425
14 BlackRock, Inc. 0.00% of their portfolio New York, NY 1,587,1611.6m $66.7m $66.7m 0.00% Reduced -58.2k -58,248
15 Lynx1 Capital Management LP 24.92% of their portfolio DORADO, PR 1,580,8411.6m $66.5m $66.5m 24.92% Reduced -213.0k -213,025
16 Driehaus Capital Management LLC 0.44% of their portfolio Chicago, IL 1,280,3371.3m $53.8m $53.8m 0.44% Reduced -78.6k -78,631
17 Woodline Partners LP 0.34% of their portfolio San Francisco, CA 1,188,5181.2m $50.0m $50.0m 0.34% Added +3.6k +3,593
18 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 1,116,8201.1m $47.0m $47.0m 0.01% Reduced -165.2k -165,160
19 UBS Group AG 0.01% of their portfolio ZURICH, V8 1,107,4381.1m $46.6m $46.6m 0.01% Added +1.1m +1,096,654
20 Pictet Asset Management Holding SA 0.05% of their portfolio CAROUGE, V8 1,031,8271.0m $43.4m $43.4m 0.05% Added +19.4k +19,379
21 WESTFIELD CAPITAL MANAGEMENT CO LP 0.18% of their portfolio BOSTON, MA 993,157993.2k $41.8m $41.8m 0.18% Added +384.7k +384,700
22 Rock Springs Capital Management LP 1.43% of their portfolio Baltimore, MD 892,549892.5k $37.5m $37.5m 1.43% Unchanged
23 MILLENNIUM MANAGEMENT LLC 0.03% of their portfolio NEW YORK, NY 883,565883.6k $37.2m $37.2m 0.03% Added +411.2k +411,184
24 MARSHALL WACE, LLP 0.05% of their portfolio LONDON, X0 862,089862.1k $36.3m $36.3m 0.05% Reduced -260.0k -260,014
25 T. Rowe Price Investment Management, Inc. 0.02% of their portfolio BALTIMORE, MD 808,576808.6k $34.0m $34.0m 0.02% Reduced -21.7k -21,692
26 ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio NASHVILLE, TN 796,957797.0k $33.5m $33.5m 0.01% Added +66.3k +66,326
27 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 786,365786.4k $33.1m $33.1m 0.01% Added +16.7k +16,712
28 Siren, L.L.C. 1.46% of their portfolio New York, NY 784,412784.4k $33.0m $33.0m 1.46% Added +102.2k +102,211
29 NOVO HOLDINGS A/S 1.91% of their portfolio HELLERUP, G7 750,000750.0k $31.5m $31.5m 1.91% Added +50.0k +50,000
30 Logos Global Management LP 3.69% of their portfolio San Francisco, CA 750,000750.0k $31.5m $31.5m 3.69% Added +175.0k +175,000
31 Cormorant Asset Management, LP 1.71% of their portfolio BOSTON, MA 740,000740.0k $31.1m $31.1m 1.71% Unchanged
32 TWO SIGMA ADVISERS, LP 0.07% of their portfolio NEW YORK, NY 720,800720.8k $30.3m $30.3m 0.07% Reduced -9.0k -9,000
33 SILVERARC CAPITAL MANAGEMENT, LLC 6.40% of their portfolio BOSTON, MA 680,845680.8k $28.6m $28.6m 6.40% Added +45.4k +45,406
34 STEMPOINT CAPITAL LP 6.48% of their portfolio NEW YORK, NY 614,812614.8k $25.9m $25.9m 6.48% Added +193.6k +193,590
35 Venrock Adviser, LLC 1.71% of their portfolio NEW YORK, NY 592,411592.4k $24.9m $24.9m 1.71% Reduced -315.6k -315,552
36 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 575,200575.2k $24.2m $24.2m 0.00% Reduced -774.6k -774,619
37 TWO SIGMA INVESTMENTS, LP 0.05% of their portfolio NEW YORK, NY 507,741507.7k $21.4m $21.4m 0.05% Reduced -85.3k -85,298
38 Artia Global Partners LP 7.87% of their portfolio MIAMI, FL 463,840463.8k $19.5m $19.5m 7.87% Added +383.7k +383,669
39 GILEAD SCIENCES, INC. 1.23% of their portfolio FOSTER CITY, CA 452,527452.5k $19.0m $19.0m 1.23% First filing
40 DAFNA Capital Management LLC 4.83% of their portfolio LOS ANGELES, CA 451,804451.8k $19.0m $19.0m 4.83% Added +39.2k +39,231
41 BAKER BROS. ADVISORS LP 0.20% of their portfolio NEW YORK, NY 450,000450.0k $18.9m $18.9m 0.20% Added +150.0k +150,000
42 Affinity Asset Advisors, LLC 2.56% of their portfolio NEW YORK, NY 389,241389.2k $16.4m $16.4m 2.56% Added +227.5k +227,500
43 Frazier Life Sciences Management, L.P. 0.65% of their portfolio PALO ALTO, CA 373,100373.1k $15.7m $15.7m 0.65% Unchanged
44 D. E. Shaw & Co., Inc. 0.02% of their portfolio New York, NY 359,048359.0k $15.1m $15.1m 0.02% Reduced -304.5k -304,541
45 Tri Locum Partners LP 3.03% of their portfolio NEW YORK, NY 347,303347.3k $14.6m $14.6m 3.03% Added +155.1k +155,146
46 TimesSquare Capital Management, LLC 0.20% of their portfolio NEW YORK, NY 331,195331.2k $13.9m $13.9m 0.20% Added +58.8k +58,760
47 Soleus Capital Management, L.P. 0.99% of their portfolio GREENWICH, CT 312,321312.3k $13.1m $13.1m 0.99% Reduced -86.0k -86,000
48 Octagon Capital Advisors LP 2.20% of their portfolio NEW YORK, NY 308,000308.0k $13.0m $13.0m 2.20% New
49 PERCEPTIVE ADVISORS LLC 0.35% of their portfolio NEW YORK, NY 300,000300.0k $12.6m $12.6m 0.35% Unchanged
50 First Turn Management, LLC 2.15% of their portfolio DEL MAR, CA 285,159285.2k $12.0m $12.0m 2.15% Reduced -22.9k -22,855
51 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 261,628261.6k $11.0m $11.0m 0.00% Added +14.7k +14,694
52 Caligan Partners LP 2.72% of their portfolio NEW YORK, NY 255,000255.0k $10.7m $10.7m 2.72% New
53 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio Boston, MA 250,000250.0k $10.5m $10.5m 0.02% Added +65.0k +65,000
54 Camber Capital Management LP 0.41% of their portfolio BOSTON, MA 250,000250.0k $10.5m $10.5m 0.41% New
55 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 242,193242.2k $10.2m $10.2m 0.00% Reduced -498.7k -498,698
56 Saturn V Capital Management LP 3.86% of their portfolio AUSTIN, TX 234,637234.6k $9.9m $9.9m 3.86% Added +103.4k +103,397
57 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 221,518221.5k $9.3m $9.3m 0.00% Reduced -33.5k -33,546
58 Qube Research & Technologies Ltd 0.01% of their portfolio LONDON, X0 191,191191.2k $8.0m $8.0m 0.01% Added +93.4k +93,414
59 Decheng Capital LLC 1.71% of their portfolio MENLO PARK, CA 189,098189.1k $8.0m $8.0m 1.71% Unchanged
60 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 187,548187.5k $7.9m $7.9m 0.01% Reduced -7.0k -7,006
61 Impax Asset Management Group plc 0.03% of their portfolio LONDON, X0 180,000180.0k $7.6m $7.6m 0.03% New
62 ALGERT GLOBAL LLC 0.17% of their portfolio SAN FRANCISCO, CA 173,114173.1k $7.3m $7.3m 0.17% Added +19.4k +19,390
63 GREAT POINT PARTNERS LLC 3.13% of their portfolio Greenwich, CT 158,092158.1k $6.6m $6.6m 3.13% Reduced -91.9k -91,908
64 STATE OF WISCONSIN INVESTMENT BOARD 0.02% of their portfolio MADISON, WI 157,865157.9k $6.6m $6.6m 0.02% Reduced -8.7k -8,653
65 CenterBook Partners LP 0.36% of their portfolio GREENWICH, CT 142,875142.9k $6.0m $6.0m 0.36% Added +124.2k +124,174
66 Alyeska Investment Group, L.P. 0.02% of their portfolio CHICAGO, IL 136,364136.4k $5.7m $5.7m 0.02% New
67 SPHERA FUNDS MANAGEMENT LTD. 1.01% of their portfolio TEL AVIV, L3 130,532130.5k $5.5m $5.5m 1.01% Reduced -17.1k -17,101
68 Nan Fung Group Holdings Ltd 4.32% of their portfolio KAI TAK, K3 120,038120.0k $5.0m $5.0m 4.32% Unchanged
69 Ally Bridge Group (NY) LLC 4.21% of their portfolio NEW YORK, NY 116,796116.8k $4.9m $4.9m 4.21% Reduced -91.4k -91,448
70 Ensign Peak Advisors, Inc 0.01% of their portfolio SALT LAKE CITY, UT 114,000114.0k $4.8m $4.8m 0.01% Unchanged
71 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 113,056113.1k $4.8m $4.8m 0.00% Added +416 +416
72 Granahan Investment Management, LLC 0.18% of their portfolio WALTHAM, MA 104,562104.6k $4.4m $4.4m 0.18% Reduced -8.7k -8,689
73 Atom Investors LP 0.53% of their portfolio AUSTIN, TX 101,757101.8k $4.3m $4.3m 0.53% New
74 Trexquant Investment LP 0.05% of their portfolio STAMFORD, CT 100,733100.7k $4.2m $4.2m 0.05% Reduced -9.7k -9,711
75 TANG CAPITAL MANAGEMENT LLC 0.28% of their portfolio SAN DIEGO, CA 100,000100.0k $4.2m $4.2m 0.28% Unchanged
76 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 98,74498.7k $4.2m $4.2m 0.00% Added +14.5k +14,544
77 Swiss National Bank 0.00% of their portfolio ZURICH, V8 93,95494.0k $4.0m $4.0m 0.00% Added +8.3k +8,300
78 Aberdeen Group plc 0.01% of their portfolio EDINBURGH, X0 87,21587.2k $3.7m $3.7m 0.01% Unchanged
79 Springhill Fund Asset Management (HK) Co Ltd 5.72% of their portfolio HONG KONG, K3 83,80083.8k $3.5m $3.5m 5.72% First filing
80 ADAR1 Capital Management, LLC 0.71% of their portfolio AUSTIN, TX 81,46081.5k $3.4m $3.4m 0.71% Reduced -71.8k -71,826
81 BOOTHBAY FUND MANAGEMENT, LLC 0.10% of their portfolio NEW YORK, NY 80,00080.0k $3.4m $3.4m 0.10% New
82 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 76,33576.3k $3.2m $3.2m 0.00% Added +29.0k +28,983
83 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 75,24075.2k $3.2m $3.2m 0.00% Reduced -11.6k -11,600
84 Rhenman & Partners Asset Management AB 0.32% of their portfolio Stockholm, V7 74,50074.5k $3.1m $3.1m 0.32% Reduced -5.0k -5,000
85 PLATINUM INVESTMENT MANAGEMENT LTD 0.17% of their portfolio SYDNEY AUSTRALIA 2000, C3 69,08569.1k $2.9m $2.9m 0.17% Unchanged
86 Eversept Partners, LP 0.30% of their portfolio NEW YORK, NY 68,25868.3k $2.9m $2.9m 0.30% Unchanged
87 Atle Fund Management AB 1.24% of their portfolio STOCKHOLM, V7 62,52162.5k $2.6m $2.6m 1.24% Added +11.8k +11,834
88 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 62,00062.0k $2.6m $2.6m 0.00% Added +3.4k +3,405
89 KBC Group NV 0.01% of their portfolio Brussels, C9 57,23457.2k $2.4m $2.4m 0.01% Added +56.0k +56,012
90 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 56,00056.0k $2.3m $2.3m 0.00% Unchanged
91 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 55,36155.4k $2.3m $2.3m 0.01% Added +1.9k +1,882
92 HighVista Strategies LLC 0.86% of their portfolio BOSTON, MA 55,03955.0k $2.3m $2.3m 0.86% Reduced -18.9k -18,941
93 Jump Financial, LLC 0.05% of their portfolio Chicago, IL 54,41254.4k $2.3m $2.3m 0.05% Reduced -20.8k -20,825
94 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.04% of their portfolio BALA CYNWYD, PA 53,93853.9k $2.3m $2.3m 0.04% First filing
95 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 52,63652.6k $2.2m $2.2m 0.00% Added +540 +540
96 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.00% of their portfolio TORONTO, A6 52,00052.0k $2.2m $2.2m 0.00% Unchanged
97 State of New Jersey Common Pension Fund D 0.01% of their portfolio TRENTON, NJ 48,26848.3k $2.0m $2.0m 0.01% Added +10.8k +10,842
98 Verition Fund Management LLC 0.01% of their portfolio GREENWICH, CT 48,16448.2k $2.0m $2.0m 0.01% Added +5.4k +5,418
99 FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio NEW YORK, NY 47,28847.3k $2.0m $2.0m 0.01% Reduced -10.7k -10,658
100 Parkman Healthcare Partners LLC 0.26% of their portfolio STAMFORD, CT 45,68045.7k $1.9m $1.9m 0.26% Added +331 +331