UROGEN PHARMA LTD URGN
COM · Common Stock · CUSIP M96088105
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($59.6k this quarter). Holder counts are more reliable. Shares outstanding: 48.7m as of 2026-05-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $17.98. Options: 5 managers hold calls ($4.3m notional), 5 hold puts ($3.8m).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 60 |
| Q4 2022 | 65 |
| Q1 2023 | 67 |
| Q2 2023 | 86 |
| Q3 2023 | 102 |
| Q4 2023 | 106 |
| Q1 2024 | 113 |
| Q2 2024 | 116 |
| Q3 2024 | 129 |
| Q4 2024 | 139 |
| Q1 2025 | 141 |
| Q2 2025 | 151 |
| Q3 2025 | 161 |
| Q4 2025 | 168 |
| Q1 2026 | 174 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 76 | 39 |
| Q3 2024 | 73 | 41 |
| Q4 2024 | 64 | 59 |
| Q1 2025 | 65 | 64 |
| Q2 2025 | 85 | 70 |
| Q3 2025 | 81 | 69 |
| Q4 2025 | 83 | 76 |
| Q1 2026 | 80 | 72 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $35.4m | $14.1m | 0.40 |
| Q3 2025 | $36.2m | $11.1m | 0.31 |
| Q4 2025 | $33.9m | $7.2m | 0.21 |
| Q1 2026 | $4.3m | $3.8m | 0.90 |
Biggest buyers
| TORONTO DOMINION BANK | New | +2.6m |
| Kynam Capital Management, LP | New | +2.2m |
| Opaleye Management Inc. | Added | +1.2m |
| Soleus Capital Management, L.P. | Added | +577.0k |
| FRONTIER CAPITAL MANAGEMENT CO LLC | Added | +532.5k |
| J. Goldman & Co LP | Added | +425.6k |
| SG Americas Securities, LLC | Added | +280.2k |
| AMERICAN CENTURY COMPANIES INC | Added | +278.8k |
| ADAR1 Capital Management, LLC | Added | +270.1k |
| BlackRock, Inc. | Added | +244.6k |
Biggest sellers
| Paradigm Biocapital Advisors LP | Reduced | -2.8m |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | Reduced | -738.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -588.2k |
| CITADEL ADVISORS LLC | Reduced | -469.8k |
| SUPERSTRING CAPITAL MANAGEMENT LP | Reduced | -331.0k |
| TCG Crossover Management, LLC | Reduced | -312.0k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -248.1k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -244.3k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Reduced | -235.8k |
| Nuveen, LLC | Reduced | -215.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.1m118.0k shares |
| J. Goldman & Co LP | Reduced | $899.0k50.0k shares |
| JANE STREET GROUP, LLC | Added | $771.3k42.9k shares |
| CITADEL ADVISORS LLC | Reduced | $275.1k15.3k shares |
| SIMPLEX TRADING, LLC | Added | $188.8k10.5k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.1m115.8k shares |
| CITADEL ADVISORS LLC | Added | $591.5k32.9k shares |
| JANE STREET GROUP, LLC | Reduced | $422.5k23.5k shares |
| GROUP ONE TRADING LLC | Reduced | $404.6k22.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $332.6k18.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| TORONTO DOMINION BANK 13G · institution +1.3 pts · filed 2026-08-12 | 6.7% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-10-27 | 6.3% |
| MORGAN STANLEY 13G · institution +3.6 pts · filed 2025-08-06 | 5.4% |
Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (3.5%, 2026-05-15), Cowen Financial Products LLC (0.0%, 2025-11-14)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 1 | $67.4k | — |
| Q3 2024 | 0 | — | 2 | $31.1k | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 2 | $132.9k | — |
| Q2 2025 | 0 | — | 1 | $38.0k | — |
| Q3 2025 | 0 | — | 2 | $465.1k | — |
| Q4 2025 | 0 | — | 2 | $287.1k | $250.0k |
| Q1 2026 | 0 | — | 2 | $292.4k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-02-03 | Smith Jason Drew General Counsel | Sold | $147.3k7.5k shares |
| 2026-02-03 | Schoenberg Mark Chief Medical Officer | Sold | $145.2k7.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| RTW INVESTMENTS, LP 0.81% of their portfolio | 4.5m $81.7m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 2.8m $51.2m | Added +244.6k |
| TORONTO DOMINION BANK 0.09% of their portfolio | 2.6m $47.0m | New |
| MORGAN STANLEY 0.00% of their portfolio | 2.6m $46.0m | Reduced -2.9k |
| Kynam Capital Management, LP 2.56% of their portfolio | 2.2m $40.4m | New |
| Jefferies Financial Group Inc. 0.48% of their portfolio | 2.2m $39.5m | Unchanged |
| Paradigm Biocapital Advisors LP 0.63% of their portfolio | 1.7m $30.6m | Reduced -2.8m |
| ACORN CAPITAL ADVISORS, LLC 8.55% of their portfolio | 1.7m $30.1m | Added +225.0k |
| SG Americas Securities, LLC 0.03% of their portfolio | 1.7m $29.8m | Added +280.2k |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 1.6m $29.4m | Added +278.8k |
| SILVERARC CAPITAL MANAGEMENT, LLC 3.18% of their portfolio | 1.5m $27.0m | Reduced -235.8k |
| Opaleye Management Inc. 3.39% of their portfolio | 1.4m $25.7m | Added +1.2m |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.24% of their portfolio | 1.3m $23.6m | Added +532.5k |
| MENORA MIVTACHIM HOLDINGS LTD. 0.10% of their portfolio | 1.2m $20.7m | Unchanged |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.0m $18.4m | Added +60.5k |
| MPM BIOIMPACT LLC 1.31% of their portfolio | 943.8k $17.0m | Added +2.4k |
| J. Goldman & Co LP 0.78% of their portfolio | 938.9k $16.9m | Added +425.6k |
| ORBIMED ADVISORS LLC 0.34% of their portfolio | 875.5k $15.7m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 874.2k $15.7m | Added +66.8k |
| Migdal Insurance & Financial Holdings Ltd. 0.12% of their portfolio | 770.9k $13.9m | Unchanged |
| Soleus Capital Management, L.P. 0.53% of their portfolio | 727.0k $13.1m | Added +577.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 598.5k $10.8m | Added +138.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 523.8k $9.4m | Added +48.6k |
| Woodline Partners LP 0.03% of their portfolio | 500.7k $9.0m | Unchanged |
| Boxer Capital Management, LLC 1.18% of their portfolio | 500.0k $9.0m | Unchanged |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 409.6k $7.4m | First filing |
| TCG Crossover Management, LLC 0.21% of their portfolio | 405.4k $7.3m | Reduced -312.0k |
| ADAR1 Capital Management, LLC 0.43% of their portfolio | 395.5k $7.1m | Added +270.1k |
| SUPERSTRING CAPITAL MANAGEMENT LP 4.98% of their portfolio | 387.4k $7.0m | Reduced -331.0k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio | 387.1k $7.0m | Reduced -738.0k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 370.9k $6.7m | Reduced -248.1k |
| TANG CAPITAL MANAGEMENT LLC 0.32% of their portfolio | 350.0k $6.3m | Unchanged |
| RICE HALL JAMES & ASSOCIATES, LLC 0.29% of their portfolio | 285.8k $5.1m | Added +4.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 275.9k $5.0m | Added +38.5k |
| Parkman Healthcare Partners LLC 0.51% of their portfolio | 275.0k $4.9m | Added +106.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 268.0k $4.8m | Reduced -469.8k |
| Privium Fund Management B.V. 0.89% of their portfolio | 238.1k $4.3m | Added +23.5k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 236.2k $4.2m | Reduced -130.5k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio | 230.6k $4.1m | Reduced -204.9k |
| Elmind Capital, LP 1.12% of their portfolio | 220.0k $4.0m | Added +120.0k |
| Ally Bridge Group (NY) LLC 3.61% of their portfolio | 202.1k $3.6m | New |
| Hennion & Walsh Asset Management, Inc. 0.11% of their portfolio | 183.5k $3.3m | Added +21.6k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 177.9k $3.2m | Reduced -63.3k |
| UBS Group AG 0.00% of their portfolio | 159.7k $2.9m | Reduced -75.4k |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 158.1k $2.8m | New |
| Atom Investors LP 0.19% of their portfolio | 145.3k $2.6m | Reduced -89.1k |
| FMR LLC 0.00% of their portfolio | 145.0k $2.6m | Added +21.4k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 144.1k $2.6m | Reduced -9.4k |
| Vestal Point Capital, LP 0.07% of their portfolio | 139.1k $2.5m | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 126.8k $2.3m | Reduced -1.8k |
| ARK Investment Management LLC 0.02% of their portfolio | 115.5k $2.1m | Reduced -5.9k |
| Aisling Capital Management LP 0.41% of their portfolio | 108.0k $1.9m | Unchanged |
| Tidal Investments LLC 0.01% of their portfolio | 102.9k $1.9m | Added +76.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 100.2k $1.8m | Reduced -25.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 98.9k $1.8m | Added +113 |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 98.1k $1.8m | Added +24.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 88.5k $1.6m | Reduced -2.5k |
| Nuveen, LLC 0.00% of their portfolio | 87.5k $1.6m | Reduced -215.1k |
| OAK RIDGE INVESTMENTS LLC 0.10% of their portfolio | 86.4k $1.6m | Added +1.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 83.6k $1.5m | Reduced -79.1k |
| Swiss National Bank 0.00% of their portfolio | 77.8k $1.4m | New |
| Trexquant Investment LP 0.01% of their portfolio | 73.9k $1.3m | New |
| TRUIST FINANCIAL CORP 0.00% of their portfolio | 72.3k $1.3m | Unchanged |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 70.2k $1.3m | Added +34.8k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 63.2k $1.1m | Added +16.0k |
| Annandale Capital, LLC 0.17% of their portfolio | 58.6k $1.1m | Reduced -2.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 55.8k $1.0m | Reduced -28.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 49.4k $888.3k | Added +3.6k |
| HRT FINANCIAL LP 0.00% of their portfolio | 49.4k $887.0k | Reduced -81.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 47.4k $852.6k | Added +47.0k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 43.5k $782.1k | Reduced -33.3k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 38.8k $696.7k | Added +36.5k |
| Coastal Bridge Advisors, LLC 0.05% of their portfolio | 37.0k $665.3k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 35.0k $820.6k | Unchanged |
| BENDER ROBERT & ASSOCIATES 0.15% of their portfolio | 34.7k $623.9k | New |
| Focus Partners Wealth 0.00% of their portfolio | 34.0k $612.0k | Reduced -1.2k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 32.5k $584.5k | Reduced -6.9k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 32.1k $577.4k | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 31.6k $567.4k | First filing |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 30.2k $542.4k | Reduced -105.9k |
| Cetera Investment Advisers 0.00% of their portfolio | 29.1k $523.1k | Reduced -1.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 28.5k $512.0k | Reduced -588.2k |
| Invesco Ltd. 0.00% of their portfolio | 28.1k $504.9k | Added +1.0k |
| HighVista Strategies LLC 0.13% of their portfolio | 26.5k $476.6k | Reduced -1.5k |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 26.0k $467.6k | First filing |
| FOX RUN MANAGEMENT, L.L.C. 0.08% of their portfolio | 25.7k $436.4k | New |
| Man Group plc 0.00% of their portfolio | 25.4k $456.6k | New |
| Legal & General Group Plc 0.00% of their portfolio | 25.2k $452.6k | Added +21.5k |
| Palo Alto Investors LP 0.07% of their portfolio | 24.5k $440.5k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 23.3k $419.4k | Added +881 |
| DIADEMA PARTNERS LP 0.17% of their portfolio | 23.2k $416.3k | Added +1.3k |
| MEITAV INVESTMENT HOUSE LTD 0.00% of their portfolio | 22.2k $399.5k | Reduced -13.3k |
| Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD 0.08% of their portfolio | 21.8k $392.4k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 21.1k $359.1k | Reduced -125.1k |
| Main Street Financial Solutions, LLC 0.03% of their portfolio | 21.0k $377.4k | Unchanged |
| MML INVESTORS SERVICES, LLC 0.00% of their portfolio | 20.8k $374.0k | Reduced -3.6k |
| Quantinno Capital Management LP 0.00% of their portfolio | 20.2k $362.8k | Reduced -3.3k |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 19.4k $348.9k | Reduced -8.0k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 19.1k $343.1k | New |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 19.0k $341.4k | Reduced -46.9k |