UROGEN PHARMA LTD URGN
COM · Common Stock · CUSIP M96088105
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.5m this quarter). Holder counts are more reliable. Shares outstanding: 46.1m as of 2025-04-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $11.06. Options: 5 managers hold calls ($1.7m notional), 5 hold puts ($542.3k).
Trends to Q1 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 60 |
| Q4 2022 | 65 |
| Q1 2023 | 67 |
| Q2 2023 | 86 |
| Q3 2023 | 102 |
| Q4 2023 | 106 |
| Q1 2024 | 113 |
| Q2 2024 | 116 |
| Q3 2024 | 129 |
| Q4 2024 | 139 |
| Q1 2025 | 141 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2023 | 45 | 31 |
| Q3 2023 | 59 | 30 |
| Q4 2023 | 64 | 31 |
| Q1 2024 | 51 | 48 |
| Q2 2024 | 76 | 39 |
| Q3 2024 | 73 | 41 |
| Q4 2024 | 64 | 59 |
| Q1 2025 | 65 | 64 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2024 | $3.2m | $4.2m | 1.33 |
| Q3 2024 | $323.3k | $1.8m | 5.65 |
| Q4 2024 | $895.6k | $223.3k | 0.25 |
| Q1 2025 | $1.7m | $542.3k | 0.32 |
Biggest buyers
| RA CAPITAL MANAGEMENT, L.P. | New | +3.2m |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Added | +3.0m |
| Vestal Point Capital, LP | Added | +523.0k |
| JPMORGAN CHASE & CO | Added | +349.8k |
| SCHRODER INVESTMENT MANAGEMENT GROUP | New | +303.4k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Added | +260.7k |
| Atom Investors LP | Added | +254.8k |
| UBS Group AG | Added | +250.4k |
| Hudson Bay Capital Management LP | Added | +177.3k |
| SG Americas Securities, LLC | Added | +142.2k |
Biggest sellers
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -1.7m |
| Cormorant Asset Management, LP | Sold out | -300.0k |
| CANTOR FITZGERALD, L. P. | Reduced | -265.0k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -222.2k |
| Opaleye Management Inc. | Sold out | -220.0k |
| GREAT POINT PARTNERS LLC | Sold out | -187.8k |
| Trexquant Investment LP | Reduced | -157.1k |
| Jefferies Financial Group Inc. | Reduced | -150.9k |
| ALLIANCEBERNSTEIN L.P. | Reduced | -128.8k |
| MARSHALL WACE, LLP | Reduced | -125.0k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $787.5k71.2k shares |
| GROUP ONE TRADING LLC | Added | $622.7k56.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $223.4k20.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $77.0k7.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $362.8k32.8k shares |
| CITADEL ADVISORS LLC | Reduced | $102.9k9.3k shares |
| GROUP ONE TRADING LLC | Reduced | $48.7k4.4k shares |
| SIMPLEX TRADING, LLC | Added | $28.0k2.6k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| TORONTO DOMINION BANK 13G · institution +1.3 pts · filed 2026-08-12 | 6.7% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-10-27 | 6.3% |
| MORGAN STANLEY 13G · institution +3.6 pts · filed 2025-08-06 | 5.4% |
Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (3.5%, 2026-05-15), Cowen Financial Products LLC (0.0%, 2025-11-14)
Insider purchases and sales in Q1 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 1 | $68.4k | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 2 | $307.2k | — |
| Q2 2024 | 0 | — | 1 | $67.4k | — |
| Q3 2024 | 0 | — | 2 | $31.1k | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 2 | $132.9k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-01-31 | Smith Jason Drew General Counsel | Sold | $82.2k7.4k shares |
| 2025-01-31 | Schoenberg Mark Chief Medical Officer | Sold | $50.7k4.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2025
| Manager | Shares | Change |
|---|---|---|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 4.4m $48.2m | Added +3.0m |
| RTW INVESTMENTS, LP 0.65% of their portfolio | 3.8m $42.4m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 0.59% of their portfolio | 3.2m $35.5m | New |
| BlackRock, Inc. 0.00% of their portfolio | 2.4m $26.8m | Reduced -43.7k |
| MENORA MIVTACHIM HOLDINGS LTD. 0.17% of their portfolio | 2.3m $25.5m | Unchanged |
| Vestal Point Capital, LP 1.70% of their portfolio | 2.2m $23.8m | Added +523.0k |
| TORONTO DOMINION BANK 0.05% of their portfolio | 1.7m $19.3m | Unchanged |
| ACORN CAPITAL ADVISORS, LLC 11.18% of their portfolio | 1.5m $16.8m | Unchanged |
| SILVERARC CAPITAL MANAGEMENT, LLC 3.19% of their portfolio | 1.4m $15.3m | Added +260.7k |
| Nantahala Capital Management, LLC 1.25% of their portfolio | 1.4m $15.1m | Reduced -8.2k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.03% of their portfolio | 1.3m $14.1m | Reduced -1.7m |
| UBS Group AG 0.00% of their portfolio | 1.2m $13.0m | Added +250.4k |
| Rosalind Advisors, Inc. 5.12% of their portfolio | 950.0k $10.5m | Added +80.0k |
| MORGAN STANLEY 0.00% of their portfolio | 857.7k $9.5m | Added +90.4k |
| Jefferies Financial Group Inc. 0.16% of their portfolio | 815.0k $9.0m | Reduced -150.9k |
| STATE STREET CORP 0.00% of their portfolio | 795.0k $8.8m | Reduced -13.0k |
| Migdal Insurance & Financial Holdings Ltd. 0.12% of their portfolio | 786.5k $8.7m | Added +100.0k |
| Wildcat Capital Management, LLC 2.93% of their portfolio | 495.6k $5.5m | Unchanged |
| DAFNA Capital Management LLC 1.54% of their portfolio | 492.5k $5.4m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 473.3k $5.2m | Added +11.4k |
| SUPERSTRING CAPITAL MANAGEMENT LP 5.59% of their portfolio | 423.6k $4.7m | Added +122.4k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 423.6k $4.7m | Reduced -222.2k |
| Hudson Bay Capital Management LP 0.03% of their portfolio | 410.6k $4.5m | Added +177.3k |
| Atom Investors LP 0.55% of their portfolio | 400.6k $4.4m | Added +254.8k |
| Parkman Healthcare Partners LLC 0.52% of their portfolio | 393.2k $4.3m | Added +23.3k |
| Harel Insurance Investments & Financial Services Ltd. 0.05% of their portfolio | 374.0k $4.1m | Reduced -89.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 371.0k $4.1m | Added +349.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 368.7k $4.1m | Reduced -25.3k |
| Stonepine Capital Management, LLC 3.59% of their portfolio | 333.4k $3.7m | Added +9.1k |
| Woodline Partners LP 0.02% of their portfolio | 306.4k $3.4m | Added +729 |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 303.4k $3.4m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 285.6k $3.2m | Reduced -24.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 284.3k $3.1m | Reduced -33.2k |
| RICE HALL JAMES & ASSOCIATES, LLC 0.17% of their portfolio | 255.8k $2.8m | Reduced -8.2k |
| VANGUARD GROUP INC 0.00% of their portfolio | 250.4k $2.8m | Reduced -46.9k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 236.0k $2.6m | Reduced -81.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 216.5k $2.4m | Reduced -5.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 196.8k $2.2m | Added +124.3k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 189.7k $2.1m | Reduced -39.1k |
| ARK Investment Management LLC 0.02% of their portfolio | 185.8k $2.1m | Added +45.6k |
| SG Americas Securities, LLC 0.01% of their portfolio | 162.5k $1.8m | Added +142.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 148.1k $1.6m | Added +1.1k |
| Epoch Investment Partners, Inc. 0.01% of their portfolio | 132.4k $1.5m | Added +6.8k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 114.1k $1.3m | Added +88.6k |
| Privium Fund Management B.V. 0.31% of their portfolio | 107.6k $1.2m | Added +79.9k |
| CANTOR FITZGERALD, L. P. 0.04% of their portfolio | 95.0k $1.1m | Reduced -265.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 93.5k $1.0m | Added +30 |
| Bank of New York Mellon Corp 0.00% of their portfolio | 93.5k $1.0m | Reduced -507 |
| Nuveen, LLC 0.00% of their portfolio | 93.0k $1.0m | First filing |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 92.9k $1.0m | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 92.0k $1.0m | Added +51.9k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 90.6k $1.0m | Reduced -47.6k |
| De Lisle Partners LLP 0.15% of their portfolio | 81.5k $902.3k | Unchanged |
| DIADEMA PARTNERS LP 0.67% of their portfolio | 76.2k $843.0k | Added +26.2k |
| Annandale Capital, LLC 0.16% of their portfolio | 75.6k $836.0k | Unchanged |
| WESBANCO BANK INC 0.03% of their portfolio | 74.4k $822.9k | Unchanged |
| OAK RIDGE INVESTMENTS LLC 0.07% of their portfolio | 73.7k $815.2k | Added +12.5k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 70.4k $778.8k | Reduced -128.8k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 69.8k $771.9k | Added +1.7k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 62.8k $694.7k | Added +43.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 53.5k $591.3k | Added +2.2k |
| TD Asset Management Inc 0.00% of their portfolio | 53.4k $590.6k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 51.2k $566.0k | Added +24.8k |
| BARCLAYS PLC 0.00% of their portfolio | 44.5k $492.6k | Reduced -24.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 38.2k $422.3k | Added +696 |
| Coastal Bridge Advisors, LLC 0.06% of their portfolio | 37.0k $409.2k | Reduced -2.0k |
| FOX RUN MANAGEMENT, L.L.C. 0.06% of their portfolio | 36.3k $401.2k | New |
| MEITAV INVESTMENT HOUSE LTD 0.01% of their portfolio | 36.1k $399.7k | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 33.8k $373.4k | Reduced -15.4k |
| Squarepoint Ops LLC 0.00% of their portfolio | 32.8k $362.4k | Reduced -17.4k |
| ALPS ADVISORS INC 0.00% of their portfolio | 32.8k $362.3k | Reduced -1.4k |
| NorthCoast Asset Management LLC 0.00% of their portfolio | 31.3k $346.1k | Unchanged |
| Tidal Investments LLC 0.00% of their portfolio | 29.7k $328.2k | Reduced -847 |
| CITIGROUP INC 0.00% of their portfolio | 29.3k $323.8k | Reduced -8.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 27.2k $300.6k | Reduced -4.1k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 26.4k $291.6k | Added +2.4k |
| XTX Topco Ltd 0.01% of their portfolio | 26.0k $287.2k | Added +7.3k |
| GROUP ONE TRADING LLC 0.01% of their portfolio | 25.4k $280.4k | Added +24.0k |
| Kynam Capital Management, LP 0.02% of their portfolio | 25.0k $276.5k | New |
| Palo Alto Investors LP 0.05% of their portfolio | 24.5k $271.0k | Unchanged |
| Main Street Financial Solutions, LLC 0.02% of their portfolio | 24.0k $265.4k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 23.3k $257.9k | Added +1.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 22.8k $251.8k | Unchanged |
| Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD 0.06% of their portfolio | 21.8k $241.2k | Unchanged |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 21.3k $235.4k | Reduced -3.2k |
| Pale Fire Capital SE 0.03% of their portfolio | 20.9k $231.1k | Added +8.4k |
| Engineers Gate Manager LP 0.00% of their portfolio | 20.3k $224.8k | Added +2.2k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 20.2k $223.2k | Added +8.9k |
| DEBUSSY CAPITAL MANAGEMENT LP 0.04% of their portfolio | 20.1k $222.6k | Unchanged |
| Corebridge Financial, Inc. 0.00% of their portfolio | 19.0k $209.6k | Reduced -282 |
| Persistent Asset Partners Ltd 0.17% of their portfolio | 17.6k $194.3k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 17.3k $191.2k | Reduced -39.6k |
| Cresset Asset Management, LLC 0.00% of their portfolio | 17.0k $187.9k | Added +271 |
| Trexquant Investment LP 0.00% of their portfolio | 15.5k $170.9k | Reduced -157.1k |
| PARTNERS CAPITAL INVESTMENT GROUP, LLP 0.00% of their portfolio | 15.4k $170.1k | New |
| Jain Global LLC 0.00% of their portfolio | 13.3k $147.0k | New |
| Invesco Ltd. 0.00% of their portfolio | 12.7k $140.6k | Reduced -746 |
| LPL Financial LLC 0.00% of their portfolio | 12.6k $139.0k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 11.5k $127.2k | Reduced -125.0k |
| SHIKIAR ASSET MANAGEMENT INC 0.04% of their portfolio | 10.8k $119.0k | Unchanged |