UROGEN PHARMA LTD URGN
COM · Common Stock · CUSIP M96088105
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.4m this quarter). Holder counts are more reliable. Shares outstanding: 42.2m as of 2024-11-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $10.65. Options: 4 managers hold calls ($895.6k notional), 4 hold puts ($223.3k).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 60 |
| Q4 2022 | 65 |
| Q1 2023 | 67 |
| Q2 2023 | 86 |
| Q3 2023 | 102 |
| Q4 2023 | 106 |
| Q1 2024 | 113 |
| Q2 2024 | 116 |
| Q3 2024 | 129 |
| Q4 2024 | 139 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 30 | 21 |
| Q2 2023 | 45 | 31 |
| Q3 2023 | 59 | 30 |
| Q4 2023 | 64 | 31 |
| Q1 2024 | 51 | 48 |
| Q2 2024 | 76 | 39 |
| Q3 2024 | 73 | 41 |
| Q4 2024 | 64 | 59 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $919.5k | $727.5k | 0.79 |
| Q2 2024 | $3.2m | $4.2m | 1.33 |
| Q3 2024 | $323.3k | $1.8m | 5.65 |
| Q4 2024 | $895.6k | $223.3k | 0.25 |
Biggest buyers
| TORONTO DOMINION BANK | New | +1.7m |
| Nantahala Capital Management, LLC | New | +1.4m |
| Vestal Point Capital, LP | Added | +1.2m |
| UBS Group AG | Added | +876.9k |
| Rosalind Advisors, Inc. | New | +870.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +381.1k |
| CANTOR FITZGERALD, L. P. | New | +360.0k |
| SUPERSTRING CAPITAL MANAGEMENT LP | New | +301.2k |
| Hudson Bay Capital Management LP | New | +233.3k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Added | +219.3k |
Biggest sellers
| COWEN AND COMPANY, LLC | Sold out | -1.8m |
| MORGAN STANLEY | Reduced | -1.4m |
| Cormorant Asset Management, LP | Reduced | -1.2m |
| Point72 Asset Management, L.P. | Reduced | -1.2m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -853.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -807.7k |
| GREAT POINT PARTNERS LLC | Reduced | -570.9k |
| STEMPOINT CAPITAL LP | Sold out | -242.0k |
| Opaleye Management Inc. | Reduced | -184.1k |
| AWM Investment Company, Inc. | Sold out | -139.9k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $614.5k57.7k shares |
| SIMPLEX TRADING, LLC | Added | $231.0k21.7k shares |
| GROUP ONE TRADING LLC | Added | $50.1k4.7k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| GROUP ONE TRADING LLC | Reduced | $114.0k10.7k shares |
| CITADEL ADVISORS LLC | Reduced | $104.4k9.8k shares |
| SIMPLEX TRADING, LLC | Reduced | $5.0k500 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| TORONTO DOMINION BANK 13G · institution +1.3 pts · filed 2026-08-12 | 6.7% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-10-27 | 6.3% |
| MORGAN STANLEY 13G · institution +3.6 pts · filed 2025-08-06 | 5.4% |
Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (3.5%, 2026-05-15), Cowen Financial Products LLC (0.0%, 2025-11-14)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 2 | $35.8k | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 1 | $68.4k | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 2 | $307.2k | — |
| Q2 2024 | 0 | — | 1 | $67.4k | — |
| Q3 2024 | 0 | — | 2 | $31.1k | — |
| Q4 2024 | 0 | — | 0 | — | — |
None reported in Q4 2024.
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| RTW INVESTMENTS, LP 0.62% of their portfolio | 3.8m $40.8m | Added +47.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio | 2.9m $31.2m | Reduced -807.7k |
| BlackRock, Inc. 0.00% of their portfolio | 2.5m $26.3m | Reduced -30.7k |
| MENORA MIVTACHIM HOLDINGS LTD. 0.15% of their portfolio | 2.3m $24.5m | Unchanged |
| TORONTO DOMINION BANK 0.04% of their portfolio | 1.7m $18.6m | New |
| Vestal Point Capital, LP 1.03% of their portfolio | 1.6m $17.4m | Added +1.2m |
| ACORN CAPITAL ADVISORS, LLC 8.69% of their portfolio | 1.5m $16.1m | First filing |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 1.4m $14.7m | Added +36.1k |
| Nantahala Capital Management, LLC 1.02% of their portfolio | 1.4m $14.6m | New |
| SILVERARC CAPITAL MANAGEMENT, LLC 2.67% of their portfolio | 1.1m $11.9m | Added +219.3k |
| Jefferies Financial Group Inc. 0.11% of their portfolio | 965.9k $10.3m | Added +929 |
| UBS Group AG 0.00% of their portfolio | 922.7k $9.8m | Added +876.9k |
| Rosalind Advisors, Inc. 4.99% of their portfolio | 870.0k $9.3m | New |
| STATE STREET CORP 0.00% of their portfolio | 808.1k $8.6m | Added +38.5k |
| MORGAN STANLEY 0.00% of their portfolio | 767.3k $8.2m | Reduced -1.4m |
| Migdal Insurance & Financial Holdings Ltd. 0.10% of their portfolio | 686.5k $7.3m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 645.8k $6.9m | Reduced -853.4k |
| Wildcat Capital Management, LLC 2.09% of their portfolio | 495.6k $5.3m | Unchanged |
| DAFNA Capital Management LLC 1.33% of their portfolio | 492.5k $5.2m | Added +33.6k |
| Harel Insurance Investments & Financial Services Ltd. 0.08% of their portfolio | 463.3k $4.9m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 461.9k $4.9m | Added +6.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 394.0k $4.2m | Added +381.1k |
| Parkman Healthcare Partners LLC 0.52% of their portfolio | 369.9k $3.9m | Added +22.3k |
| CANTOR FITZGERALD, L. P. 0.14% of their portfolio | 360.0k $3.8m | New |
| Stonepine Capital Management, LLC 2.79% of their portfolio | 324.3k $3.5m | Added +44.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 317.5k $3.4m | Added +1.6k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 317.1k $3.4m | Reduced -1.2m |
| NORTHERN TRUST CORP 0.00% of their portfolio | 310.1k $3.3m | Added +23.3k |
| Woodline Partners LP 0.02% of their portfolio | 305.6k $3.3m | Unchanged |
| SUPERSTRING CAPITAL MANAGEMENT LP 2.82% of their portfolio | 301.2k $3.2m | New |
| Cormorant Asset Management, LP 0.18% of their portfolio | 300.0k $3.2m | Reduced -1.2m |
| VANGUARD GROUP INC 0.00% of their portfolio | 297.4k $3.2m | Added +12.9k |
| RICE HALL JAMES & ASSOCIATES, LLC 0.15% of their portfolio | 264.0k $2.8m | Reduced -7.9k |
| Hudson Bay Capital Management LP 0.02% of their portfolio | 233.3k $2.5m | New |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 228.8k $2.4m | Reduced -13.3k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 221.5k $2.4m | Added +5.8k |
| Opaleye Management Inc. 0.41% of their portfolio | 220.0k $2.3m | Reduced -184.1k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 199.3k $2.1m | Added +175.9k |
| GREAT POINT PARTNERS LLC 0.94% of their portfolio | 187.8k $2.0m | Reduced -570.9k |
| Trexquant Investment LP 0.02% of their portfolio | 172.6k $1.8m | Reduced -99.1k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 147.0k $1.6m | Added +9.7k |
| Atom Investors LP 0.19% of their portfolio | 145.7k $1.6m | New |
| ARK Investment Management LLC 0.01% of their portfolio | 140.1k $1.5m | Added +18.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 138.2k $1.5m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 136.5k $1.5m | New |
| Epoch Investment Partners, Inc. 0.01% of their portfolio | 125.7k $1.3m | Reduced -11.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 94.0k $1.0m | Added +6.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 93.5k $996.0k | Added +3.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 93.0k $990.0k | Reduced -56.4k |
| De Lisle Partners LLP 0.13% of their portfolio | 81.5k $867.7k | Unchanged |
| Annandale Capital, LLC 0.16% of their portfolio | 75.6k $805.0k | Unchanged |
| WESBANCO BANK INC 0.03% of their portfolio | 74.4k $792.4k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 72.5k $771.8k | Added +6.0k |
| BARCLAYS PLC 0.00% of their portfolio | 69.3k $738.3k | Added +9.5k |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 68.1k $725.3k | Reduced -56.2k |
| OAK RIDGE INVESTMENTS LLC 0.05% of their portfolio | 61.2k $651.4k | Reduced -15.6k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 56.9k $605.9k | Reduced -30.1k |
| Swiss National Bank 0.00% of their portfolio | 56.6k $602.8k | Unchanged |
| TD Asset Management Inc 0.00% of their portfolio | 53.4k $568.7k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 51.3k $546.0k | Added +1.4k |
| Squarepoint Ops LLC 0.00% of their portfolio | 50.2k $534.6k | Reduced -57.5k |
| DIADEMA PARTNERS LP 0.60% of their portfolio | 50.0k $532.5k | First filing |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 49.2k $523.5k | Added +4.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 40.1k $427.4k | Added +3.1k |
| Coastal Bridge Advisors, LLC 0.10% of their portfolio | 39.0k $415.4k | Reduced -1.5k |
| CITIGROUP INC 0.00% of their portfolio | 38.0k $404.8k | Added +9.9k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 37.5k $399.2k | Added +24.0k |
| MEITAV INVESTMENT HOUSE LTD 0.01% of their portfolio | 36.1k $384.8k | Unchanged |
| BENDER ROBERT & ASSOCIATES 0.09% of their portfolio | 34.7k $369.6k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 34.1k $363.4k | Reduced -28 |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 33.6k $358.0k | New |
| NorthCoast Asset Management LLC 0.00% of their portfolio | 31.3k $333.2k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 31.3k $333.0k | Added +11.9k |
| Tidal Investments LLC 0.00% of their portfolio | 30.5k $325.1k | Reduced -7.1k |
| Verition Fund Management LLC 0.00% of their portfolio | 28.7k $305.4k | Added +15.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 28.2k $300.0k | Added +246 |
| Privium Fund Management B.V. 0.07% of their portfolio | 27.7k $294.9k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 26.3k $280.5k | Reduced -4.4k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 25.5k $271.5k | Reduced -92.5k |
| Palo Alto Investors LP 0.04% of their portfolio | 24.5k $260.9k | Unchanged |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 24.5k $260.7k | Reduced -4.1k |
| Main Street Financial Solutions, LLC 0.03% of their portfolio | 24.0k $255.6k | Unchanged |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 24.0k $255.5k | Added +11.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 22.8k $242.5k | Added +2.7k |
| Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD 0.06% of their portfolio | 21.8k $232.2k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 21.7k $230.8k | Added +969 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 21.1k $224.9k | Reduced -115.0k |
| SG Americas Securities, LLC 0.00% of their portfolio | 20.3k $216.0k | Added +6.2k |
| DEBUSSY CAPITAL MANAGEMENT LP 0.03% of their portfolio | 20.1k $210.9k | Unchanged |
| FMR LLC 0.00% of their portfolio | 20.0k $212.7k | Reduced -3.1k |
| Legal & General Group Plc 0.00% of their portfolio | 19.8k $211.3k | Added +3.9k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio | 19.5k $208.1k | First filing |
| Corebridge Financial, Inc. 0.00% of their portfolio | 19.2k $204.9k | Reduced -988 |
| XTX Topco Ltd 0.02% of their portfolio | 18.6k $198.5k | Reduced -4.7k |
| Engineers Gate Manager LP 0.00% of their portfolio | 18.1k $193.0k | Reduced -2.0k |
| Jump Financial, LLC 0.00% of their portfolio | 17.2k $183.0k | Reduced -39.3k |
| Cresset Asset Management, LLC 0.00% of their portfolio | 16.7k $178.0k | Unchanged |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 14.0k $149.0k | New |
| Corton Capital Inc. 0.08% of their portfolio | 13.9k $147.6k | Reduced -1.8k |
| Invesco Ltd. 0.00% of their portfolio | 13.5k $143.3k | Added +634 |