Vault-13

ENTERA BIO LTD ENTX

SHS · Common Stock · CUSIP M40527109

22 institutional holders +0 vs Q3 2025
9,342,8779.3m shares reported held*
20.4% of all shares outstanding*
$18.1mreported value*
3 new 6 added 4 reduced 4 sold out net sold ≈ $3.0k (-1.5k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 45.9m as of 2025-11-10, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.94. Options: 1 managers hold calls ($14.7k notional), 0 hold puts (—).

Trends to Q4 2025

Institutional holders

Managers reporting a position, each quarter

0102030Q3 22: 10Q4 22: 13Q1 23: 10Q2 23: 13Q3 23: 13Q4 23: 11Q1 24: 16Q2 24: 16Q3 24: 18Q4 24: 15Q1 25: 19Q2 25: 20Q3 25: 22Q4 25: 2222Q3 22Q2 23Q1 24Q4 24Q4 25
Numbers
QuarterHolders
Q3 202210
Q4 202213
Q1 202310
Q2 202313
Q3 202313
Q4 202311
Q1 202416
Q2 202416
Q3 202418
Q4 202415
Q1 202519
Q2 202520
Q3 202522
Q4 202522

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
10010Q1 24: 10 bought or addedQ1 24: 3 cut or sold outQ2 24: 7 bought or addedQ2 24: 8 cut or sold outQ2 24Q3 24: 6 bought or addedQ3 24: 4 cut or sold outQ4 24: 7 bought or addedQ4 24: 7 cut or sold outQ4 24Q1 25: 8 bought or addedQ1 25: 3 cut or sold outQ2 25: 9 bought or addedQ2 25: 6 cut or sold outQ2 25Q3 25: 9 bought or addedQ3 25: 8 cut or sold outQ4 25: 9 bought or addedQ4 25: 8 cut or sold outQ4 25
Numbers
QuarterBought or addedCut or sold out
Q1 2024103
Q2 202478
Q3 202464
Q4 202477
Q1 202583
Q2 202596
Q3 202598
Q4 202598

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20k$40k$60kQ1 25 calls: $53.5kQ1 25 puts: $170Q1 25P/C 0.00Q2 25 calls: $950Q2 25 puts: $0Q2 25P/C 0.00Q3 25 calls: $40.9kQ3 25 puts: $0Q3 25P/C 0.00Q4 25 calls: $14.7kQ4 25 puts: $0Q4 25P/C 0.00
Numbers
QuarterCallsPutsP/C
Q1 2025$53.5k$1700.00
Q2 2025$950$00.00
Q3 2025$40.9k$00.00
Q4 2025$14.7k$00.00

Biggest buyers

JANE STREET GROUP, LLC Added +43,536+43.5k
Schonfeld Strategic Advisors LLC Added +29,629+29.6k
HighTower Advisors, LLC Added +25,000+25.0k
RENAISSANCE TECHNOLOGIES LLC Added +19,601+19.6k
SUPERSTRING CAPITAL MANAGEMENT LP New +17,142+17.1k
Point72 Asset Management, L.P. Added +15,210+15.2k
GOLDMAN SACHS GROUP INC New +12,327+12.3k
GSA CAPITAL PARTNERS LLP New +11,890+11.9k
CITADEL ADVISORS LLC Added +252+252

Biggest sellers

BESSEMER GROUP INC Sold out -140,843-140.8k
XTX Topco Ltd Sold out -10,771-10.8k
UBS Group AG Reduced -10,435-10.4k
BANK OF AMERICA CORP /DE/ Reduced -6,000-6.0k
Parkman Healthcare Partners LLC Reduced -5,749-5.7k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -2,267-2.3k
SIMPLEX TRADING, LLC Sold out -69-69
SBI Securities Co., Ltd. Sold out -1-1

Biggest calls

GROUP ONE TRADING LLC Added $14.7k7.6k shares

Biggest puts

None

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
BIOTECHNOLOGY VALUE FUND L P 13D · may seek influence new · filed 2026-08-04
Stated purposeThe Reporting Persons purchased the securities reported owned herein based on the Reporting Persons' belief that such securities, when purchased, were undervalued and represented an attractive investment opportunity. Depending upon overall market conditions, other investment opportunities available to the Reporting Persons, and the availability of Shares at prices that would make the purchase or sale of Shares desirable, the Reporting Persons may endeavor to increase or decrease their position in the Issuer through, among other things, the purchase or sale of Shares on the open market or in private transactions or otherwise, on such terms and at such times as the Reporting Persons may deem advisable. April Securities Purchase Agreement and Registration Rights Agreement On April 1, 2026, … Full filing
10.0% new 17.2m≈ $30.5m 2026-08-04
OPKO HEALTH, INC. 13G · passive investor new · filed 2025-04-02 8.1% new 3.7m≈ $6.5m 2025-04-02
TCG Crossover GP III, LLC 13G · passive investor new · filed 2026-08-04 7.1% new 12.3m≈ $21.7m 2026-08-04
Vivo Opportunity Fund Holdings, L.P. 13G · passive investor new · filed 2026-08-04 6.9% new 11.8m≈ $20.9m 2026-08-04

Fell to 5% or below in the last year: Longitude Capital Partners V, LLC (4.6%, 2026-08-04), Seven Fleet Capital Management LP (4.1%, 2026-08-04)

Insider purchases and sales in Q4 2025

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
101Q1 24: 1 buyingQ1 24: 0 sellingQ2 24: 0 buyingQ2 24: 0 sellingQ2 24Q3 24: 0 buyingQ3 24: 0 sellingQ4 24: 0 buyingQ4 24: 0 sellingQ4 24Q1 25: 0 buyingQ1 25: 0 sellingQ2 25: 0 buyingQ2 25: 0 sellingQ2 25Q3 25: 0 buyingQ3 25: 0 sellingQ4 25: 1 buyingQ4 25: 0 sellingQ4 25
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q1 20241$15.3k0——
Q2 20240—0——
Q3 20240—0——
Q4 20240—0——
Q1 20250—0——
Q2 20250—0——
Q3 20250—0——
Q4 20251$19.9k0——
DateInsiderTradeSharesPrice ValueTheir holding
2025-12-29 Toledano Miranda Jayne Chief Executive Officer, director Bought 11,000 $1.81 $19.9k11.0k shares +3%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q4 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Knoll Capital Management, LLC 5.23% of their portfolio MIAMI, FL 5,881,8795.9m $11.4m $11.4m 5.23% Unchanged
2 Point72 Asset Management, L.P. 0.00% of their portfolio STAMFORD, CT 1,193,6531.2m $2.3m $2.3m 0.00% Added +15.2k +15,210
3 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 627,330627.3k $1.2m $1.2m 0.00% Unchanged
4 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 596,585596.6k $1.2m $1.2m 0.01% Added +29.6k +29,629
5 Parkman Healthcare Partners LLC 0.05% of their portfolio STAMFORD, CT 275,073275.1k $533.6k $533.6k 0.05% Reduced -5.7k -5,749
6 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 148,668148.7k $288.4k $288.4k 0.00% Unchanged
7 Seven Fleet Capital Management LP 0.18% of their portfolio MOUNTAIN VIEW, CA 135,318135.3k $262.5k $262.5k 0.18% First filing
8 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 108,001108.0k $209.5k $209.5k 0.00% Added +19.6k +19,601
9 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 74,06474.1k $143.7k $143.7k 0.00% Added +43.5k +43,536
10 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 64,91064.9k $125.9k $125.9k 0.00% Reduced -2.3k -2,267
11 SIGNATURE ESTATE & INVESTMENT ADVISORS LLC 0.00% of their portfolio LOS ANGELES, CA 47,32847.3k $91.8k $91.8k 0.00% Unchanged
12 HighTower Advisors, LLC 0.00% of their portfolio CHICAGO, IL 43,14043.1k $83.7k $83.7k 0.00% Added +25.0k +25,000
13 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 40,23040.2k $78.0k $78.0k 0.00% Added +252 +252
14 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 21,13621.1k $41.0k $41.0k 0.00% Unchanged
15 Gem Investment Advisors, LLC 0.04% of their portfolio TEANECK, NJ 19,13519.1k $37.1k $37.1k 0.04% First filing
16 SUPERSTRING CAPITAL MANAGEMENT LP 0.02% of their portfolio NEW YORK, NY 17,14217.1k $33.3k $33.3k 0.02% New
17 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 15,00015.0k $29.1k $29.1k 0.00% Reduced -6.0k -6,000
18 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 12,32712.3k $23.9k $23.9k 0.00% New
19 GSA CAPITAL PARTNERS LLP 0.00% of their portfolio LONDON, X0 11,89011.9k $23.0k $23.0k 0.00% New
20 PNC Financial Services Group, Inc. 0.00% of their portfolio Pittsburgh, PA 10,00010.0k $19.4k $19.4k 0.00% Unchanged
21 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 5151 $99 $99 0.00% Unchanged
22 UBS Group AG 0.00% of their portfolio ZURICH, V8 1717 $33 $33 0.00% Reduced -10.4k -10,435