CRISPR THERAPEUTICS AG CRSP
NAMEN AKT · Common Stock · CUSIP H17182108
Company in Basel, Switzerland
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersZug, Switzerland
- Founded2013
- Websitecrisprtx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($11.6k this quarter). Holder counts are more reliable. Shares outstanding: 79.4m as of 2023-08-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $56.10. Options: 28 managers hold calls ($141.6m notional), 23 hold puts ($111.6m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 437 |
| Q4 2022 | 398 |
| Q1 2023 | 381 |
| Q2 2023 | 419 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 159 | 206 |
| Q1 2023 | 149 | 175 |
| Q2 2023 | 155 | 161 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $223.2m | $212.7m | 0.95 |
| Q4 2022 | $109.4m | $86.2m | 0.79 |
| Q1 2023 | $79.7m | $71.8m | 0.90 |
| Q2 2023 | $141.6m | $111.6m | 0.79 |
Biggest buyers
| MARSHALL WACE, LLP | New | +457.0k |
| FRONTIER CAPITAL MANAGEMENT CO LLC | Added | +329.4k |
| BANK OF AMERICA CORP /DE/ | Added | +236.9k |
| Contrarius Investment Management Ltd | New | +229.7k |
| TWO SIGMA INVESTMENTS, LP | Added | +217.0k |
| Man Group plc | New | +131.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP | Added | +98.8k |
| FIRST TRUST ADVISORS LP | New | +96.4k |
| CREDIT SUISSE AG/ | Added | +74.4k |
| Carnegie Investment Counsel | New | +60.8k |
Biggest sellers
| FMR LLC | Reduced | -2.2m |
| ARK Investment Management LLC | Reduced | -651.7k |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | -439.8k |
| Amova Asset Management Americas, Inc. | Reduced | -438.8k |
| STATE STREET CORP | Reduced | -353.7k |
| ARMISTICE CAPITAL, LLC | Reduced | -324.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -220.3k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -207.3k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -167.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -133.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $23.5m418.4k shares |
| JANE STREET GROUP, LLC | Added | $21.8m388.6k shares |
| CITADEL ADVISORS LLC | Added | $19.1m340.0k shares |
| Ikarian Capital, LLC | New | $11.2m200.0k shares |
| IMC-Chicago, LLC | Reduced | $9.4m167.6k shares |
| Caption Management, LLC | New | $9.0m160.3k shares |
| SIMPLEX TRADING, LLC | Added | $8.5m151.6k shares |
| Walleye Trading LLC | Reduced | $8.4m149.9k shares |
| D. E. Shaw & Co., Inc. | Reduced | $5.2m92.5k shares |
| GROUP ONE TRADING LLC | Added | $4.3m76.8k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $22.9m407.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $14.7m262.4k shares |
| Ikarian Capital, LLC | New | $11.2m200.0k shares |
| Caption Management, LLC | New | $9.5m170.0k shares |
| GROUP ONE TRADING LLC | Added | $7.3m129.9k shares |
| JANE STREET GROUP, LLC | Added | $6.8m120.4k shares |
| Squarepoint Ops LLC | Reduced | $6.5m115.3k shares |
| IMC-Chicago, LLC | Added | $6.3m112.4k shares |
| SIMPLEX TRADING, LLC | Added | $4.9m87.4k shares |
| GOLDMAN SACHS GROUP INC | Unchanged | $4.0m71.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARK Investment Management LLC 13G · institution +1.0 pts · filed 2026-04-30 | 11.8% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-07-27 | 8.3% |
| ORBIS INVESTMENT MANAGEMENT LTD 13G · institution -0.7 pts · filed 2026-08-14 | 5.6% |
| Capital World Investors 13G · institution new · filed 2026-05-14 | 5.1% |
Fell to 5% or below in the last year: Capital International Investors (1.2%, 2026-02-05)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 1 | $1.5m | — |
| Q3 2022 | 0 | — | 1 | $5.2m | — |
| Q4 2022 | 0 | — | 1 | $3.7m | — |
| Q1 2023 | 0 | — | 1 | $3.6m | — |
| Q2 2023 | 0 | — | 1 | $2.9m | $2.9m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-05-30 | Kulkarni Samarth Chief Executive Officer, director | Sold plan | $1.6m25.0k shares |
| 2023-04-25 | Kulkarni Samarth Chief Executive Officer, director | Sold plan | $1.3m25.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| ARK Investment Management LLC 2.73% of their portfolio | 7.3m $412.0m | Reduced -651.7k |
| Capital International Investors 0.08% of their portfolio | 6.1m $340.8m | Added +46.1k |
| T. Rowe Price Investment Management, Inc. 0.14% of their portfolio | 3.6m $204.7m | Reduced -17.8k |
| Sumitomo Mitsui Trust Group, Inc. 0.15% of their portfolio | 3.5m $198.4m | Reduced -439.8k |
| Amova Asset Management Americas, Inc. 2.09% of their portfolio | 3.5m $198.3m | Reduced -438.8k |
| BlackRock Inc. 0.00% of their portfolio | 2.7m $152.6m | Reduced -80.0k |
| FMR LLC 0.01% of their portfolio | 2.1m $117.4m | Reduced -2.2m |
| STATE STREET CORP 0.00% of their portfolio | 1.6m $91.6m | Reduced -353.7k |
| NEA Management Company, LLC 6.80% of their portfolio | 1.6m $89.1m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.5m $86.0m | Added +46.5k |
| LOOMIS SAYLES & CO L P 0.10% of their portfolio | 1.1m $64.4m | Reduced -8.9k |
| CREDIT SUISSE AG/ 0.05% of their portfolio | 921.7k $51.7m | Added +74.4k |
| Bellevue Group AG 0.72% of their portfolio | 899.3k $50.5m | Reduced -500 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 882.4k $49.5m | Reduced -220.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 834.6k $46.9m | Added +24.6k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 754.6k $42.4m | Added +236.9k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 711.3k $39.9m | Reduced -48.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 646.7k $36.3m | Added +5.9k |
| NORGES BANK 0.01% of their portfolio | 577.0k $32.4m | Reduced -52.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 551.4k $31.0m | Reduced -31.3k |
| FEDERATED HERMES, INC. 0.07% of their portfolio | 508.8k $28.6m | Unchanged |
| ARMISTICE CAPITAL, LLC 0.70% of their portfolio | 500.0k $28.1m | Reduced -324.0k |
| Versant Venture Management, LLC 33.20% of their portfolio | 498.6k $28.0m | Unchanged |
| MARSHALL WACE, LLP 0.06% of their portfolio | 457.0k $25.7m | New |
| TWO SIGMA INVESTMENTS, LP 0.06% of their portfolio | 433.1k $24.3m | Added +217.0k |
| MORGAN STANLEY 0.00% of their portfolio | 390.8k $21.9m | Reduced -79.7k |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.20% of their portfolio | 375.8k $21.1m | Added +329.4k |
| BARCLAYS PLC 0.01% of their portfolio | 373.2k $21.0m | Added +11.4k |
| Allspring Global Investments Holdings, LLC 0.03% of their portfolio | 326.7k $18.3m | Added +17.9k |
| RENAISSANCE TECHNOLOGIES LLC 0.02% of their portfolio | 287.8k $16.2m | Reduced -207.3k |
| UBS Group AG 0.01% of their portfolio | 262.7k $14.7m | Added +17.8k |
| BAILLIE GIFFORD & CO 0.01% of their portfolio | 243.6k $13.7m | Reduced -19.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 239.2k $13.4m | Added +40.3k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 233.2k $13.1m | Added +35 |
| Contrarius Investment Management Ltd 0.69% of their portfolio | 229.7k $12.9m | New |
| Valiant Capital Management, L.P. 1.83% of their portfolio | 229.0k $12.9m | Unchanged |
| CAPITAL ADVISORS INC/OK 0.31% of their portfolio | 216.0k $12.1m | Added +50.2k |
| TD Asset Management Inc 0.01% of their portfolio | 213.1k $12.0m | Added +3.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 200.4k $11.3m | Reduced -6.2k |
| Mirae Asset Global Investments Co., Ltd. 0.02% of their portfolio | 167.6k $9.4m | Reduced -3.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 163.7k $9.2m | Reduced -133.1k |
| Swiss National Bank 0.01% of their portfolio | 162.7k $9.1m | Added +2.2k |
| Rafferty Asset Management, LLC 0.05% of their portfolio | 146.9k $8.2m | Reduced -10.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 137.5k $7.7m | Reduced -100.0k |
| Invesco Ltd. 0.00% of their portfolio | 134.1k $7.5m | Reduced -3.2k |
| BLAIR WILLIAM & CO/IL 0.03% of their portfolio | 132.9k $7.5m | Added +3.7k |
| Man Group plc 0.02% of their portfolio | 131.7k $7.4m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 129.3k $7.3m | Added +45.9k |
| Squarepoint Ops LLC 0.04% of their portfolio | 127.4k $7.2m | Reduced -3.5k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio | 126.8k $7.1m | Added +98.8k |
| LAZARD ASSET MANAGEMENT LLC 0.01% of their portfolio | 118.9k $6.7m | Reduced -4.9k |
| CITIGROUP INC 0.01% of their portfolio | 108.5k $6.1m | Reduced -82.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 108.1k $6.1m | Reduced -772 |
| California Public Employees Retirement System 0.01% of their portfolio | 106.0k $5.9m | Unchanged |
| Integral Health Asset Management, LLC 0.74% of their portfolio | 100.0k $5.6m | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 99.0k $5.6m | Added +2.8k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 96.5k $5.4m | Reduced -37.7k |
| FIRST TRUST ADVISORS LP 0.01% of their portfolio | 96.4k $5.4m | New |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 95.3k $5.5m | Reduced -5.9k |
| CAPITAL INTERNATIONAL LTD /CA/ 0.30% of their portfolio | 95.2k $5.3m | Added +2.6k |
| LPL Financial LLC 0.00% of their portfolio | 90.8k $5.1m | Added +9.0k |
| WESTWOOD HOLDINGS GROUP INC 0.05% of their portfolio | 90.0k $5.1m | Reduced -3.5k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 88.0k $4.9m | Reduced -86.4k |
| Rokos Capital Management LLP 0.10% of their portfolio | 87.5k $4.9m | Unchanged |
| CAPITAL INTERNATIONAL SARL 0.22% of their portfolio | 85.4k $4.8m | Added +8.1k |
| OSAIC HOLDINGS, INC. 0.01% of their portfolio | 85.2k $4.8m | Added +191 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 82.3k $3.7m | Unchanged |
| VAN ECK ASSOCIATES CORP 0.01% of their portfolio | 76.8k $4.3m | Reduced -5.9k |
| EFG Asset Management (North America) Corp. 0.90% of their portfolio | 75.0k $4.2m | Reduced -20.1k |
| GROUP ONE TRADING LLC 0.18% of their portfolio | 74.0k $4.2m | Added +27.6k |
| Rockefeller Capital Management L.P. 0.02% of their portfolio | 73.6k $4.1m | First filing |
| GUGGENHEIM CAPITAL LLC 0.03% of their portfolio | 69.5k $3.9m | Reduced -5.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 65.7k $3.7m | Added +403 |
| Capital International, Inc./CA/ 0.07% of their portfolio | 65.2k $3.7m | Added +4.2k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 65.1k $3.7m | Reduced -3.5k |
| Legal & General Group Plc 0.00% of their portfolio | 64.4k $3.6m | Added +3.3k |
| Slow Capital, Inc. 0.62% of their portfolio | 63.8k $3.6m | Reduced -2.9k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 62.2k $3.5m | Reduced -167.7k |
| Carnegie Investment Counsel 0.13% of their portfolio | 60.8k $3.4m | New |
| SEI INVESTMENTS CO 0.01% of their portfolio | 57.9k $3.2m | Reduced -6.8k |
| McGuire Investment Group, LLC 0.60% of their portfolio | 57.0k $3.2m | Added +4.1k |
| CLOUGH CAPITAL PARTNERS L P 0.32% of their portfolio | 57.0k $3.2m | Reduced -65.1k |
| Allianz Asset Management GmbH 0.01% of their portfolio | 55.8k $3.1m | Added +1.7k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 52.8k $3.0m | Added +5.2k |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 51.9k $2.9m | Unchanged |
| Woodline Partners LP 0.03% of their portfolio | 50.0k $2.8m | New |
| Reynders McVeigh Capital Management, LLC 0.18% of their portfolio | 50.0k $2.8m | Added +31.1k |
| Thrivent Financial for Lutherans 0.01% of their portfolio | 48.8k $2.7m | Reduced -401 |
| Soleus Capital Management, L.P. 0.26% of their portfolio | 42.4k $2.4m | New |
| CAPITAL FUND MANAGEMENT S.A. 0.04% of their portfolio | 42.0k $2.4m | Added +29.8k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 41.1k $2.3m | Added +720 |
| HighTower Advisors, LLC 0.00% of their portfolio | 40.0k $2.2m | Reduced -228 |
| DekaBank Deutsche Girozentrale 0.01% of their portfolio | 40.0k $2.3m | Added +20.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 37.9k $2.1m | New |
| ExodusPoint Capital Management, LP 0.02% of their portfolio | 36.6k $2.1m | Reduced -16.3k |
| Trexquant Investment LP 0.05% of their portfolio | 36.1k $2.0m | New |
| West Family Investments, Inc. 0.77% of their portfolio | 35.5k $2.0m | Unchanged |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 34.8k $2.0m | Unchanged |
| Green Alpha Advisors, LLC 1.27% of their portfolio | 34.4k $1.9m | Added +1.8k |
| HERSHEY TRUST CO 0.01% of their portfolio | 33.8k $1.9m | Unchanged |