AC IMMUNE SA ACIU
SHS · Common Stock · CUSIP H00263105
- SectorHealth care
- IndustryPharmaceutical Preparations
- FilingsSEC EDGAR
43
institutional holders
+0 vs Q1 2025
24.5m
shares reported held*
$49.7mreported value*
4 new
17 added
11 reduced
4 sold out
net sold ≈ $2.9m (-1.4m shares)
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $2.03. Options: 2 managers hold calls ($812 notional), 3 hold puts ($93.2k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 35 |
| Q4 2022 | 38 |
| Q1 2023 | 35 |
| Q2 2023 | 32 |
| Q3 2023 | 29 |
| Q4 2023 | 33 |
| Q1 2024 | 38 |
| Q2 2024 | 46 |
| Q3 2024 | 44 |
| Q4 2024 | 46 |
| Q1 2025 | 43 |
| Q2 2025 | 43 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Bought or addedCut or sold out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 11 | 11 |
| Q4 2023 | 18 | 9 |
| Q1 2024 | 23 | 11 |
| Q2 2024 | 21 | 22 |
| Q3 2024 | 13 | 25 |
| Q4 2024 | 21 | 21 |
| Q1 2025 | 19 | 22 |
| Q2 2025 | 21 | 15 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
CallsPuts
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $783.0k | $236.6k | 0.30 |
| Q4 2024 | $143.5k | $6.8k | 0.05 |
| Q1 2025 | $88.9k | $42.5k | 0.48 |
| Q2 2025 | $812 | $93.2k | 114.75 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | Added | +78.8k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +40.5k |
| TWO SIGMA INVESTMENTS, LP | New | +30.7k |
| WELLS FARGO & COMPANY/MN | Added | +27.0k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +24.9k |
| GOLDMAN SACHS GROUP INC | New | +10.4k |
| TWO SIGMA SECURITIES, LLC | New | +10.1k |
| CANTOR FITZGERALD, L. P. | Added | +10.0k |
| TWO SIGMA ADVISERS, LP | Added | +5.2k |
| NORTHERN TRUST CORP | Added | +4.3k |
Biggest sellers
| BlackRock, Inc. | Reduced | -745.3k |
| PLATINUM INVESTMENT MANAGEMENT LTD | Sold out | -739.3k |
| MARSHALL WACE, LLP | Reduced | -76.3k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -38.9k |
| Handelsbanken Fonder AB | Reduced | -25.0k |
| Squarepoint Ops LLC | Reduced | -9.8k |
| UBS Group AG | Reduced | -9.2k |
| Banque Cantonale Vaudoise | Reduced | -8.3k |
| CITADEL ADVISORS LLC | Reduced | -5.5k |
| Tower Research Capital LLC (TRC) | Reduced | -3.8k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $812400 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $57.9k28.5k shares |
| GROUP ONE TRADING LLC | New | $35.3k17.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| BVF INC/IL 1.44% of their portfolio | 19.8m $40.2m | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1.0m $2.1m | Added +27.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 828.3k $1.7m | Added +24.9k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 411.7k $820.0k | Added +40.5k |
| BlackRock, Inc. 0.00% of their portfolio | 411.3k $835.0k | Reduced -745.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 381.4k $774.1k | Added +4.3k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 291.5k $591.8k | Added +78.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 253.4k $514.4k | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 198.7k $403.1k | Reduced -38.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 146.0k $296.4k | Reduced -5.5k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 135.8k $275.8k | Reduced -76.3k |
| Handelsbanken Fonder AB 0.00% of their portfolio | 105.0k $213.0k | Reduced -25.0k |
| Eversept Partners, LP 0.02% of their portfolio | 100.8k $204.5k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 72.9k $148.0k | Added +891 |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 63.6k $129.1k | Reduced -489 |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 30.7k $62.3k | New |
| CANTOR FITZGERALD, L. P. 0.00% of their portfolio | 30.0k $60.9k | Added +10.0k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 28.8k $58.5k | Added +5.2k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 24.9k $50.5k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 20.2k $40.9k | Added +330 |
| Banque Cantonale Vaudoise 0.00% of their portfolio | 18.4k $37.0k | Reduced -8.3k |
| Squarepoint Ops LLC 0.00% of their portfolio | 12.6k $25.7k | Reduced -9.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 10.4k $21.0k | New |
| Quinn Opportunity Partners LLC 0.00% of their portfolio | 10.1k $20.5k | Unchanged |
| TWO SIGMA SECURITIES, LLC 0.00% of their portfolio | 10.1k $20.5k | New |
| Silverberg Bernstein Capital Management LLC 0.01% of their portfolio | 10.0k $20.3k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 7.9k $16.1k | Added +498 |
| UBS Group AG 0.00% of their portfolio | 7.5k $15.2k | Reduced -9.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 6.1k $12.4k | Reduced -997 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 5.6k $11.3k | Added +3.1k |
| State of Tennessee, Department of Treasury 0.00% of their portfolio | 5.1k $10.4k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.9k $7.9k | Added +570 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 3.2k $6.0k | Added +1.5k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 3.1k $6.2k | Reduced -3.8k |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 2.5k $5.0k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 1.9k $3.9k | Added +476 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1.3k $2.7k | Added +116 |
| Activest Wealth Management 0.00% of their portfolio | 1.0k $2.0k | Unchanged |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 565 $1.1k | Added +4 |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 318 $0 | Added +34 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 251 $509 | New |
| Strengthening Families & Communities, LLC 0.00% of their portfolio | 200 $406 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |