MEIRAGTX HLDGS PLC MGTX
COM · Common Stock · CUSIP G59665102
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersNew York, NY
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($96.3k this quarter). Holder counts are more reliable. Shares outstanding: 80.4m as of 2025-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.53. Options: 5 managers hold calls ($317.9k notional), 4 hold puts ($188.2k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 100 |
| Q4 2022 | 99 |
| Q1 2023 | 92 |
| Q2 2023 | 80 |
| Q3 2023 | 76 |
| Q4 2023 | 87 |
| Q1 2024 | 97 |
| Q2 2024 | 96 |
| Q3 2024 | 100 |
| Q4 2024 | 103 |
| Q1 2025 | 119 |
| Q2 2025 | 113 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 27 | 34 |
| Q4 2023 | 44 | 29 |
| Q1 2024 | 48 | 38 |
| Q2 2024 | 48 | 43 |
| Q3 2024 | 46 | 36 |
| Q4 2024 | 56 | 36 |
| Q1 2025 | 65 | 37 |
| Q2 2025 | 52 | 61 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $87.2k | $264.2k | 3.03 |
| Q4 2024 | $1.7m | $233.6k | 0.14 |
| Q1 2025 | $1.3m | $373.4k | 0.29 |
| Q2 2025 | $317.9k | $188.2k | 0.59 |
Biggest buyers
| Rubric Capital Management LP | Added | +2.0m |
| Prosight Management, LP | Added | +895.9k |
| J. Goldman & Co LP | Added | +885.8k |
| MILLENNIUM MANAGEMENT LLC | New | +785.2k |
| ROYAL BANK OF CANADA | Added | +599.1k |
| 22NW, LP | New | +586.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +400.0k |
| Long Focus Capital Management, LLC | Added | +275.0k |
| BANK OF AMERICA CORP /DE/ | Added | +221.8k |
| CITADEL ADVISORS LLC | Added | +154.1k |
Biggest sellers
| Woodline Partners LP | Sold out | -803.5k |
| ROYCE & ASSOCIATES LP | Reduced | -390.8k |
| Invesco Ltd. | Reduced | -306.2k |
| BlackRock, Inc. | Reduced | -266.0k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -242.6k |
| Affinity Asset Advisors, LLC | Sold out | -150.0k |
| Knott David M Jr | Sold out | -125.0k |
| Janney Montgomery Scott LLC | Sold out | -122.2k |
| Informed Momentum Co LLC | Sold out | -83.0k |
| Russell Investments Group, Ltd. | Reduced | -75.8k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $168.2k25.8k shares |
| SIMPLEX TRADING, LLC | Added | $76.0k11.7k shares |
| J. Goldman & Co LP | Reduced | $69.8k10.7k shares |
| GROUP ONE TRADING LLC | Reduced | $3.9k600 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $88.7k13.6k shares |
| GROUP ONE TRADING LLC | Added | $79.5k12.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $20.0k3.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| PERCEPTIVE ADVISORS LLC 13D · may seek influence -0.3 pts · filed 2026-04-24 | 12.6% |
| Rubric Capital Management LP 13G · institution +1.9 pts · filed 2026-08-14 | 9.8% |
Fell to 5% or below in the last year: Adage Capital Management, L.P. (4.9%, 2026-05-13), Prosight Management, LP (4.0%, 2026-02-13)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 1 | $5.0m | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 2 | $456.3k | $456.3k |
| Q2 2025 | 0 | — | 2 | $397.6k | $397.6k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-04-22 | Giroux Richard CFO & COO | Sold plan | $144.0k24.0k shares |
| 2025-04-08 | Forbes Alexandria PRESIDENT & CEO, director | Sold plan | $253.7k47.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| PERCEPTIVE ADVISORS LLC 3.09% of their portfolio | 12.6m $82.2m | Added +45.0k |
| Sanofi 45.25% of their portfolio | 12.2m $79.5m | Unchanged |
| JOHNSON & JOHNSON 13.14% of their portfolio | 6.6m $43.9m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.07% of their portfolio | 6.0m $39.3m | Added +400.0k |
| Prosight Management, LP 7.29% of their portfolio | 4.6m $29.9m | Added +895.9k |
| Rubric Capital Management LP 0.39% of their portfolio | 3.7m $24.3m | Added +2.0m |
| BlackRock, Inc. 0.00% of their portfolio | 2.9m $18.7m | Reduced -266.0k |
| 683 Capital Management, LLC 1.78% of their portfolio | 2.7m $17.5m | Added +115.0k |
| J. Goldman & Co LP 0.42% of their portfolio | 2.0m $13.3m | Added +885.8k |
| Knoll Capital Management, LLC 5.79% of their portfolio | 1.2m $8.2m | Unchanged |
| Erste Asset Management GmbH 0.04% of their portfolio | 789.7k $5.2m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 785.2k $5.1m | New |
| STATE STREET CORP 0.00% of their portfolio | 682.2k $4.4m | Added +38.1k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 607.8k $4.0m | Added +599.1k |
| 22NW, LP 2.41% of their portfolio | 586.5k $3.8m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 557.6k $3.6m | Reduced -40.3k |
| Long Focus Capital Management, LLC 0.22% of their portfolio | 524.7k $3.4m | Added +275.0k |
| MORGAN STANLEY 0.00% of their portfolio | 454.4k $3.0m | Added +114.8k |
| VANGUARD GROUP INC 0.00% of their portfolio | 420.7k $2.7m | Reduced -28.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 273.9k $1.8m | Reduced -39.5k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 266.7k $1.7m | Added +221.8k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 222.4k $1.5m | Added +15.4k |
| ROYCE & ASSOCIATES LP 0.01% of their portfolio | 217.1k $1.4m | Reduced -390.8k |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.09% of their portfolio | 208.3k $1.4m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 201.6k $1.3m | Added +154.1k |
| Privium Fund Management B.V. 0.23% of their portfolio | 163.0k $1.1m | Added +46.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 149.8k $976.8k | Reduced -242.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 146.5k $955.3k | Reduced -56.6k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 140.9k $918.7k | New |
| Nuveen, LLC 0.00% of their portfolio | 139.1k $907.2k | Reduced -10.1k |
| READYSTATE ASSET MANAGEMENT LP 0.04% of their portfolio | 133.4k $869.8k | Reduced -56.2k |
| BLAIR WILLIAM & CO/IL 0.00% of their portfolio | 132.5k $864.1k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 108.2k $705.5k | Reduced -2.4k |
| BARCLAYS PLC 0.00% of their portfolio | 108.1k $704.9k | Added +24.3k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 106.6k $695.2k | Added +24.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 104.7k $682.9k | Reduced -11.3k |
| HRT FINANCIAL LP 0.00% of their portfolio | 102.6k $668.0k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 88.6k $577.5k | Reduced -37.1k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 81.2k $529.6k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 79.4k $517.6k | Reduced -75.8k |
| UBS Group AG 0.00% of their portfolio | 72.9k $475.3k | Added +10.1k |
| Fort Sheridan Advisors LLC 0.06% of their portfolio | 68.4k $446.1k | Reduced -1.3k |
| Hennion & Walsh Asset Management, Inc. 0.02% of their portfolio | 64.1k $418.1k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 63.7k $415.4k | Added +5.5k |
| Sender Co & Partners, Inc. 0.18% of their portfolio | 60.6k $395.4k | New |
| DAVENPORT & Co LLC 0.00% of their portfolio | 55.2k $359.9k | Reduced -1.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 54.6k $355.9k | Added +4.2k |
| BROWN ADVISORY INC 0.00% of their portfolio | 50.0k $326.0k | New |
| Quantinno Capital Management LP 0.00% of their portfolio | 48.9k $318.8k | New |
| LETKO, BROSSEAU & ASSOCIATES INC 0.01% of their portfolio | 45.3k $295.4k | Unchanged |
| TOCQUEVILLE ASSET MANAGEMENT L.P. 0.00% of their portfolio | 44.5k $290.1k | Added +2.0k |
| Invesco Ltd. 0.00% of their portfolio | 44.2k $287.9k | Reduced -306.2k |
| CreativeOne Wealth, LLC 0.01% of their portfolio | 36.6k $238.5k | Reduced -17 |
| KENNEDY CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 35.2k $229.4k | Added +1.3k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 32.5k $212.0k | Reduced -32 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 30.8k $201.1k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 29.1k $189.9k | Reduced -22.1k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 26.8k $175.0k | Reduced -12.7k |
| Squarepoint Ops LLC 0.00% of their portfolio | 25.3k $164.8k | New |
| LEVIN CAPITAL STRATEGIES, L.P. 0.02% of their portfolio | 25.0k $163.0k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 24.9k $162.1k | Reduced -3.7k |
| SkyView Investment Advisors, LLC 0.02% of their portfolio | 24.0k $156.0k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 23.0k $149.6k | Reduced -1.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 22.8k $148.7k | Reduced -4.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 22.8k $149.0k | Added +1.8k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 21.4k $139.6k | Added +9.2k |
| PUREfi Wealth, LLC 0.10% of their portfolio | 20.0k $130.4k | Added +10.0k |
| CITIGROUP INC 0.00% of their portfolio | 18.3k $119.2k | Reduced -18.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 16.8k $109.7k | Reduced -45 |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 16.6k $108.1k | Reduced -7.9k |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 16.1k $105.2k | Added +465 |
| CIBC Private Wealth Group LLC 0.00% of their portfolio | 15.0k $97.8k | Unchanged |
| Hobbs Group Advisors, LLC 0.03% of their portfolio | 14.2k $92.7k | New |
| Creative Planning 0.00% of their portfolio | 12.8k $83.3k | Reduced -25.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 12.6k $82.2k | Reduced -12.6k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 12.2k $79.8k | Unchanged |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 11.9k $77.3k | Reduced -6.5k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 11.7k $76.0k | Unchanged |
| ProShare Advisors LLC 0.00% of their portfolio | 11.5k $75.3k | Reduced -2.2k |
| Family Manage LLC 0.01% of their portfolio | 10.0k $65.2k | Unchanged |
| FNY Investment Advisers, LLC 0.03% of their portfolio | 9.4k $61.0k | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 9.3k $60.4k | Added +4.7k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 8.8k $57.4k | Added +7.0k |
| CWM, LLC 0.00% of their portfolio | 8.4k $55.0k | Reduced -240 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 7.3k $47.4k | Unchanged |
| FMR LLC 0.00% of their portfolio | 5.5k $35.6k | Added +2.0k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 4.9k $31.8k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 4.8k $31.4k | Added +1.5k |
| Legal & General Group Plc 0.00% of their portfolio | 4.4k $28.8k | Reduced -348 |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.1k $20.2k | Added +489 |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 3.0k $19.0k | Reduced -1.0k |
| Versant Capital Management, Inc 0.00% of their portfolio | 2.3k $14.7k | Added +1.8k |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 2.0k $13.0k | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 1.8k $12.0k | Reduced -204 |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 1.8k $11.4k | New |
| AMALGAMATED BANK 0.00% of their portfolio | 1.6k $10.0k | Unchanged |
| Atlantic Union Bankshares Corp 0.00% of their portfolio | 800 $5.2k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 490 $3.2k | Added +195 |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 330 $2.0k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 250 $1.6k | Added +150 |