JAZZ PHARMACEUTICALS PLC JAZZ
SHS USD · Common Stock · CUSIP G50871105
Irish tax-registered pharmaceutical corporation
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersIreland, Ireland
- Founded2003
- Websitejazzpharma.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($59.7m this quarter). Holder counts are more reliable. Shares outstanding: 60.8m as of 2025-10-29, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $169.84. Options: 19 managers hold calls ($174.6m notional), 12 hold puts ($50.2m).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 469 |
| Q4 2022 | 486 |
| Q1 2023 | 473 |
| Q2 2023 | 471 |
| Q3 2023 | 486 |
| Q4 2023 | 500 |
| Q1 2024 | 481 |
| Q2 2024 | 456 |
| Q3 2024 | 479 |
| Q4 2024 | 509 |
| Q1 2025 | 551 |
| Q2 2025 | 503 |
| Q3 2025 | 503 |
| Q4 2025 | 574 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 233 | 227 |
| Q2 2024 | 217 | 247 |
| Q3 2024 | 234 | 209 |
| Q4 2024 | 236 | 228 |
| Q1 2025 | 311 | 208 |
| Q2 2025 | 243 | 282 |
| Q3 2025 | 223 | 253 |
| Q4 2025 | 287 | 246 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $66.4m | $24.7m | 0.37 |
| Q2 2025 | $69.8m | $8.3m | 0.12 |
| Q3 2025 | $129.7m | $23.7m | 0.18 |
| Q4 2025 | $174.6m | $50.2m | 0.29 |
Biggest buyers
| FULLER & THALER ASSET MANAGEMENT, INC. | Added | +1.7m |
| FRANKLIN RESOURCES INC | Added | +1.1m |
| MILLENNIUM MANAGEMENT LLC | Added | +933.6k |
| Bank of New York Mellon Corp | Added | +715.4k |
| Qube Research & Technologies Ltd | Added | +444.2k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +395.0k |
| Sofinnova Investments, Inc. | Added | +371.0k |
| Allianz Asset Management GmbH | Added | +242.9k |
| Zurcher Kantonalbank (Zurich Cantonalbank) | Added | +197.1k |
| AQR CAPITAL MANAGEMENT LLC | Added | +178.3k |
Biggest sellers
| JPMORGAN CHASE & CO | Reduced | -2.7m |
| GOLDENTREE ASSET MANAGEMENT LP | Reduced | -716.8k |
| CITADEL ADVISORS LLC | Reduced | -572.8k |
| Perpetual Ltd | Reduced | -448.0k |
| Balyasny Asset Management L.P. | Reduced | -385.0k |
| AMERIPRISE FINANCIAL INC | Reduced | -326.4k |
| Schonfeld Strategic Advisors LLC | Reduced | -297.2k |
| Estuary Capital Management LP | Reduced | -256.8k |
| Woodline Partners LP | Reduced | -223.7k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -213.3k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $41.7m245.3k shares |
| Ikarian Capital, LLC | Added | $28.9m170.0k shares |
| BARCLAYS PLC | Added | $27.0m158.7k shares |
| DIADEMA PARTNERS LP | Added | $17.9m105.3k shares |
| JANE STREET GROUP, LLC | Added | $13.2m77.6k shares |
| IMC-Chicago, LLC | Added | $10.8m63.5k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $7.6m44.7k shares |
| KVP Capital Advisors, LP | First filing | $5.3m31.0k shares |
| GROUP ONE TRADING LLC | Added | $4.4m25.8k shares |
| PEAK6 LLC | New | $4.4m25.6k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $20.2m118.9k shares |
| CITADEL ADVISORS LLC | Added | $11.7m68.7k shares |
| LMR Partners LLP | New | $8.5m50.0k shares |
| JANE STREET GROUP, LLC | Added | $3.8m22.5k shares |
| DLD Asset Management, LP | New | $1.5m8.6k shares |
| SIMPLEX TRADING, LLC | Added | $935.0k5.5k shares |
| Walleye Trading LLC | New | $918.0k5.4k shares |
| Squarepoint Ops LLC | New | $629.0k3.7k shares |
| GROUP ONE TRADING LLC | Added | $595.0k3.5k shares |
| Walleye Capital LLC | New | $561.0k3.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution new · filed 2026-08-06 | 7.4% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 1 | $1.4m | 1 | $438.4k | — |
| Q2 2024 | 0 | — | 2 | $566.0k | — |
| Q3 2024 | 0 | — | 1 | $152.7k | — |
| Q4 2024 | 0 | — | 3 | $816.3k | $242.3k |
| Q1 2025 | 0 | — | 4 | $4.1m | $2.1m |
| Q2 2025 | 1 | $10.0m | 1 | $470.9k | $470.9k |
| Q3 2025 | 0 | — | 1 | $992.5k | $992.5k |
| Q4 2025 | 0 | — | 6 | $22.7m | $2.0m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-12-09 | Henderson Mary Elizabeth SVP, Technical Operations | Sold | $379.4k2.2k shares |
| 2025-12-05 | Carr Patricia SVP, Chief Accounting Officer | Sold | $797.8k4.7k shares |
| 2025-11-26 | COZADD BRUCE C Director | Sold | $13.8m77.5k shares |
| 2025-11-20 | McSharry Heather Ann Director | Sold | $607.1k3.4k shares |
| 2025-11-18 | COZADD BRUCE C Director | Sold | $3.3m18.0k shares |
| 2025-11-18 | Winningham Rick E Director | Sold | $994.7k5.5k shares |
| 2025-11-18 | Carr Patricia SVP, Chief Accounting Officer | Sold | $968.4k5.3k shares |
| 2025-11-17 | Iannone Robert EVP, Global Head of R&D & CMO | Sold plan | $1.2m7.2k shares |
| 2025-10-03 | COZADD BRUCE C Director | Sold plan | $490.0k3.5k shares |
| 2025-10-01 | COZADD BRUCE C Director | Sold plan | $263.6k2.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.01% of their portfolio | 5.9m $1.0bn | Added +10.2k |
| BlackRock, Inc. 0.02% of their portfolio | 5.5m $926.7m | Reduced -108.1k |
| FULLER & THALER ASSET MANAGEMENT, INC. 0.97% of their portfolio | 3.4m $570.2m | Added +1.7m |
| Capital World Investors 0.06% of their portfolio | 2.7m $453.3m | Added +111.7k |
| DIMENSIONAL FUND ADVISORS LP 0.09% of their portfolio | 2.6m $446.0m | Reduced -213.3k |
| LSV ASSET MANAGEMENT 0.91% of their portfolio | 2.5m $417.5m | Reduced -55.9k |
| STATE STREET CORP 0.01% of their portfolio | 1.8m $312.4m | Reduced -30.1k |
| FRANKLIN RESOURCES INC 0.08% of their portfolio | 1.8m $309.2m | Added +1.1m |
| EcoR1 Capital, LLC 13.24% of their portfolio | 1.7m $290.1m | Unchanged |
| AMERIPRISE FINANCIAL INC 0.06% of their portfolio | 1.5m $258.6m | Reduced -326.4k |
| MILLENNIUM MANAGEMENT LLC 0.15% of their portfolio | 1.2m $204.5m | Added +933.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 1.2m $203.6m | Added +1.1k |
| Bank of New York Mellon Corp 0.03% of their portfolio | 1.2m $197.5m | Added +715.4k |
| Swedbank AB 0.18% of their portfolio | 1.1m $187.5m | Added +28.9k |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 1.0m $177.6m | Reduced -2.7m |
| Sofinnova Investments, Inc. 7.04% of their portfolio | 959.9k $163.2m | Added +371.0k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 915.1k $155.6m | Reduced -52.8k |
| AQR CAPITAL MANAGEMENT LLC 0.08% of their portfolio | 877.3k $149.1m | Added +178.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.22% of their portfolio | 836.8k $142.3m | Reduced -88.1k |
| FMR LLC 0.01% of their portfolio | 800.9k $136.2m | Added +118.8k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.14% of their portfolio | 706.0k $120.0m | Added +148.6k |
| Pacer Advisors, Inc. 0.29% of their portfolio | 647.1k $110.0m | Added +107.1k |
| MORGAN STANLEY 0.01% of their portfolio | 639.2k $108.7m | Reduced -78.4k |
| GMT Capital Corp 5.66% of their portfolio | 638.5k $108.5m | Reduced -154.3k |
| Allianz Asset Management GmbH 0.12% of their portfolio | 598.8k $101.8m | Added +242.9k |
| Holocene Advisors, LP 0.21% of their portfolio | 589.7k $100.3m | Reduced -15.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.14% of their portfolio | 548.0k $93.2m | Added +395.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.08% of their portfolio | 547.7k $93.1m | Added +31.4k |
| Qube Research & Technologies Ltd 0.12% of their portfolio | 500.5k $85.1m | Added +444.2k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 476.9k $81.1m | Reduced -26.7k |
| UBS Group AG 0.02% of their portfolio | 473.0k $80.4m | Added +18.5k |
| Polaris Capital Management, LLC 6.10% of their portfolio | 432.5k $73.5m | Reduced -81.0k |
| GW&K Investment Management, LLC 0.63% of their portfolio | 427.6k $72.7m | Reduced -27.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 424.3k $72.1m | Reduced -43.2k |
| GOLDENTREE ASSET MANAGEMENT LP 3.87% of their portfolio | 420.3k $71.3m | Reduced -716.8k |
| SYSTEMATIC FINANCIAL MANAGEMENT LP 1.59% of their portfolio | 396.9k $67.5m | Added +2.5k |
| Boston Trust Walden Corp 0.51% of their portfolio | 393.9k $67.0m | Reduced -14.9k |
| Nuveen, LLC 0.02% of their portfolio | 381.9k $64.9m | Reduced -6.8k |
| Alyeska Investment Group, L.P. 0.16% of their portfolio | 323.4k $55.0m | Added +117.4k |
| CITADEL ADVISORS LLC 0.04% of their portfolio | 311.1k $52.9m | Reduced -572.8k |
| Iron Triangle Partners LP 5.68% of their portfolio | 292.2k $49.7m | Added +142.2k |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 291.4k $49.5m | Added +74.9k |
| THOMPSON SIEGEL & WALMSLEY LLC 0.83% of their portfolio | 290.2k $49.3m | Reduced -83.7k |
| Vestal Point Capital, LP 1.81% of their portfolio | 290.0k $49.3m | Reduced -210.0k |
| Rockefeller Capital Management L.P. 0.08% of their portfolio | 265.1k $45.1m | Reduced -11.8k |
| VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio | 249.7k $42.4m | Reduced -55.7k |
| Saturn V Capital Management LP 7.74% of their portfolio | 248.1k $42.2m | Reduced -52.5k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.08% of their portfolio | 228.6k $38.9m | Added +197.1k |
| BANK OF MONTREAL /CAN/ 0.02% of their portfolio | 223.3k $38.0m | Reduced -113.8k |
| Logos Global Management LP 2.27% of their portfolio | 200.0k $34.0m | Unchanged |
| D. E. Shaw & Co., Inc. 0.03% of their portfolio | 199.3k $33.9m | Added +74.9k |
| Invesco Ltd. 0.00% of their portfolio | 191.3k $32.5m | Added +20.1k |
| WEDGE CAPITAL MANAGEMENT L L P/NC 0.58% of their portfolio | 188.9k $32.1m | Reduced -22.3k |
| Pictet Asset Management Holding SA 0.03% of their portfolio | 184.7k $31.5m | Reduced -33.5k |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.33% of their portfolio | 182.2k $31.0m | Added +143.7k |
| RAYMOND JAMES FINANCIAL INC 0.01% of their portfolio | 177.3k $30.2m | Added +18.5k |
| Point72 Asset Management, L.P. 0.05% of their portfolio | 175.0k $29.8m | Added +163.1k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 174.5k $29.7m | Added +9.4k |
| Quantinno Capital Management LP 0.06% of their portfolio | 174.4k $29.6m | Added +137.5k |
| PERCEPTIVE ADVISORS LLC 0.53% of their portfolio | 170.0k $28.9m | New |
| Krensavage Asset Management, LLC 10.08% of their portfolio | 167.8k $28.5m | Unchanged |
| Retirement Systems of Alabama 0.09% of their portfolio | 167.7k $28.5m | Reduced -20.7k |
| Ikarian Capital, LLC 3.53% of their portfolio | 160.4k $27.3m | Added +82.6k |
| Aristotle Capital Management, LLC 0.05% of their portfolio | 158.8k $27.0m | Added +781 |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 158.2k $26.9m | Reduced -6.4k |
| Perpetual Ltd 0.38% of their portfolio | 154.7k $26.3m | Reduced -448.0k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 148.3k $25.2m | Reduced -21.4k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 140.3k $23.8m | Added +124.9k |
| Schonfeld Strategic Advisors LLC 0.12% of their portfolio | 139.2k $23.7m | Reduced -297.2k |
| ExodusPoint Capital Management, LP 0.26% of their portfolio | 137.6k $23.4m | Added +116.5k |
| SG Americas Securities, LLC 0.03% of their portfolio | 136.0k $23.1m | Added +131.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 130.6k $22.2m | Reduced -4.0k |
| SummitTX Capital, L.P. 0.65% of their portfolio | 126.8k $21.6m | Added +103.8k |
| STIFEL FINANCIAL CORP 0.02% of their portfolio | 122.7k $20.9m | Reduced -3.2k |
| HOTCHKIS & WILEY CAPITAL MANAGEMENT LLC 0.06% of their portfolio | 119.0k $20.2m | Reduced -19.1k |
| LOOMIS SAYLES & CO L P 0.02% of their portfolio | 116.4k $19.8m | Reduced -11.5k |
| Walleye Capital LLC 0.11% of their portfolio | 115.8k $19.7m | Added +33.0k |
| DekaBank Deutsche Girozentrale 0.02% of their portfolio | 115.1k $14.0m | Unchanged |
| California Public Employees Retirement System 0.01% of their portfolio | 112.7k $19.2m | Reduced -82.1k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 112.6k $19.1m | Reduced -16.6k |
| SEI INVESTMENTS CO 0.02% of their portfolio | 110.4k $18.8m | Added +10.1k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.05% of their portfolio | 109.9k $15.0m | Reduced -14.8k |
| Distillate Capital Partners LLC 0.96% of their portfolio | 109.8k $18.7m | Reduced -1.6k |
| STOREBRAND ASSET MANAGEMENT AS 0.05% of their portfolio | 109.1k $18.6m | Reduced -1.3k |
| Swiss National Bank 0.01% of their portfolio | 107.7k $18.3m | Reduced -3.7k |
| Estuary Capital Management LP 3.22% of their portfolio | 106.4k $18.1m | Reduced -256.8k |
| KBC Group NV 0.04% of their portfolio | 103.3k $17.6m | Added +7.1k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.01% of their portfolio | 102.8k $17.5m | Added +16.1k |
| Engineers Gate Manager LP 0.20% of their portfolio | 100.8k $17.1m | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 100.5k $17.1m | Added +13.7k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 96.4k $16.4m | Reduced -30.9k |
| Legal & General Group Plc 0.00% of their portfolio | 95.9k $16.3m | Reduced -24.0k |
| BARCLAYS PLC 0.01% of their portfolio | 95.3k $16.2m | Added +29.7k |
| PANAGORA ASSET MANAGEMENT INC 0.06% of their portfolio | 93.8k $15.9m | Added +92.3k |
| Robeco Institutional Asset Management B.V. 0.02% of their portfolio | 93.6k $15.9m | Reduced -2.8k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.02% of their portfolio | 90.1k $15.3m | Added +25.0k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 88.1k $15.0m | Reduced -14.1k |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 87.1k $14.8m | Reduced -186.2k |
| BANK OF NOVA SCOTIA 0.02% of their portfolio | 86.2k $14.7m | New |
| MACKENZIE FINANCIAL CORP 0.02% of their portfolio | 83.5k $14.2m | Reduced -124.2k |