ASTRAZENECA PLC AZN
ORD · Common Stock · CUSIP G0593M107
British-Swedish pharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, Sweden
- Founded1913
- Websiteastrazeneca.com
- FilingsSEC EDGAR
Q4 2025 share counts are adjusted for a 1-for-2 stock split, so holders aren't shown as buying or selling because of it.
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($196.8m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $196.03. Options: 23 managers hold calls ($847.0m notional), 32 hold puts ($1.4bn).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 3 |
| Q4 2022 | 4 |
| Q1 2023 | 5 |
| Q2 2023 | 4 |
| Q3 2023 | 2 |
| Q4 2023 | 3 |
| Q1 2024 | 4 |
| Q2 2024 | 4 |
| Q3 2024 | 4 |
| Q4 2024 | 3 |
| Q1 2025 | 4 |
| Q2 2025 | 5 |
| Q3 2025 | 7 |
| Q4 2025 | 54 |
| Q1 2026 | 1,329 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 2 | 1 |
| Q3 2024 | 1 | 2 |
| Q4 2024 | 1 | 2 |
| Q1 2025 | 0 | 2 |
| Q2 2025 | 2 | 2 |
| Q3 2025 | 6 | 0 |
| Q4 2025 | 50 | 3 |
| Q1 2026 | 1,271 | 28 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $0 | $0 | — |
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $36.8k | $0 | 0.00 |
| Q1 2026 | $847.0m | $1.4bn | 1.71 |
Biggest buyers
| INVESTOR AB | New | +51.6m |
| Capital International Investors | New | +34.4m |
| FMR LLC | New | +29.6m |
| Capital World Investors | New | +28.3m |
| Legal & General Group Plc | New | +25.8m |
| WELLINGTON MANAGEMENT GROUP LLP | New | +23.8m |
| PRICE T ROWE ASSOCIATES INC /MD/ | New | +19.5m |
| BANK OF AMERICA CORP /DE/ | New | +19.1m |
| JPMORGAN CHASE & CO | New | +18.6m |
| PRIMECAP MANAGEMENT CO/CA/ | New | +18.2m |
Biggest sellers
| L & S Advisors Inc | Reduced | -18.7k |
| May Hill Capital, LLC | Reduced | -3.3k |
| Icon Wealth Advisors, LLC | Reduced | -1.8k |
| Valeo Financial Advisors, LLC | Reduced | -1.2k |
| Boston Common Asset Management, LLC | Reduced | -752 |
| MONETARY MANAGEMENT GROUP INC | Reduced | -375 |
| BURLING WEALTH PARTNERS, LLC | Reduced | -357 |
| Guardian Wealth Management, Inc. | Reduced | -344 |
| EverSource Wealth Advisors, LLC | Reduced | -299 |
| Elyxium Wealth, LLC | Sold out | -292 |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $229.4m1.2m shares |
| CITADEL ADVISORS LLC | New | $125.6m637.0k shares |
| SIH Partners, LLLP | New | $67.1m340.1k shares |
| JANE STREET GROUP, LLC | New | $65.9m334.1k shares |
| GOLDMAN SACHS GROUP INC | New | $58.8m298.0k shares |
| MILLENNIUM MANAGEMENT LLC | New | $57.2m69.7k shares |
| DRW Securities, LLC | New | $44.4m225.0k shares |
| IMC-Chicago, LLC | New | $38.2m193.7k shares |
| Optiver Holding B.V. | New | $33.6m170.4k shares |
| UBS Group AG | New | $31.4m159.2k shares |
Biggest puts
| MILLENNIUM MANAGEMENT LLC | New | $587.7m40.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $246.0m1.2m shares |
| DRW Securities, LLC | New | $106.9m542.0k shares |
| Optiver Holding B.V. | New | $103.9m527.0k shares |
| SIH Partners, LLLP | New | $82.0m415.7k shares |
| BNP PARIBAS FINANCIAL MARKETS | New | $60.1m3.0k shares |
| CITIGROUP INC | New | $38.7m200.0k shares |
| GOLDMAN SACHS GROUP INC | New | $34.9m176.9k shares |
| UBS Group AG | New | $31.0m157.2k shares |
| JANE STREET GROUP, LLC | New | $26.6m134.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-04-23 | 7.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-28 | 5.0% |
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q1 2026.
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| INVESTOR AB 67.27% of their portfolio | 51.6m $10.2bn | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.22% of their portfolio | 45.0m $8.8bn | First filing |
| Capital International Investors 1.58% of their portfolio | 34.4m $6.7bn | New |
| FMR LLC 0.31% of their portfolio | 29.6m $5.8bn | New |
| Capital World Investors 0.75% of their portfolio | 28.3m $5.5bn | New |
| Legal & General Group Plc 1.16% of their portfolio | 25.8m $5.0bn | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.86% of their portfolio | 23.8m $4.6bn | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.44% of their portfolio | 19.5m $3.8bn | New |
| BANK OF AMERICA CORP /DE/ 0.27% of their portfolio | 19.1m $3.8bn | New |
| JPMORGAN CHASE & CO 0.24% of their portfolio | 18.6m $3.6bn | New |
| VANGUARD ASSET MANAGEMENT, Ltd 3.10% of their portfolio | 18.5m $3.6bn | First filing |
| PRIMECAP MANAGEMENT CO/CA/ 2.83% of their portfolio | 18.2m $3.6bn | New |
| FRANKLIN RESOURCES INC 0.86% of their portfolio | 17.8m $3.5bn | New |
| Amundi 0.83% of their portfolio | 15.4m $3.0bn | New |
| VANGUARD FIDUCIARY TRUST CO 0.65% of their portfolio | 13.2m $2.6bn | First filing |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 2.29% of their portfolio | 12.9m $2.5bn | New |
| DEUTSCHE BANK AG\ 0.79% of their portfolio | 12.1m $2.4bn | New |
| JANUS HENDERSON GROUP PLC 1.11% of their portfolio | 11.9m $2.3bn | New |
| AVIVA PLC 3.60% of their portfolio | 11.1m $2.1bn | New |
| Fisher Asset Management, LLC 0.73% of their portfolio | 10.8m $2.1bn | New |
| GOLDMAN SACHS GROUP INC 0.27% of their portfolio | 10.6m $2.1bn | New |
| ROYAL BANK OF CANADA 0.39% of their portfolio | 10.4m $2.0bn | New |
| ROYAL LONDON ASSET MANAGEMENT LTD 4.26% of their portfolio | 10.3m $2.0bn | New |
| Invesco Ltd. 0.19% of their portfolio | 10.1m $2.0bn | New |
| Rathbones Group PLC 3.22% of their portfolio | 8.1m $1.6bn | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 1.72% of their portfolio | 7.6m $1.5bn | New |
| CAUSEWAY CAPITAL MANAGEMENT LLC 17.66% of their portfolio | 7.4m $1.4bn | New |
| Sanders Capital, LLC 1.66% of their portfolio | 7.1m $1.4bn | New |
| MORGAN STANLEY 0.08% of their portfolio | 7.0m $1.4bn | New |
| Nuveen, LLC 0.36% of their portfolio | 6.8m $1.3bn | New |
| Bank of New York Mellon Corp 0.24% of their portfolio | 6.7m $1.3bn | New |
| Allianz Asset Management GmbH 1.46% of their portfolio | 6.5m $1.3bn | New |
| Swiss National Bank 0.69% of their portfolio | 6.2m $1.2bn | New |
| UBS Group AG 0.21% of their portfolio | 6.0m $1.2bn | New |
| SEB Asset Management AB 4.95% of their portfolio | 6.0m $1.2bn | First filing |
| AMERIPRISE FINANCIAL INC 0.26% of their portfolio | 5.7m $1.1bn | New |
| BARCLAYS PLC 0.39% of their portfolio | 5.5m $1.1bn | New |
| ALLIANCEBERNSTEIN L.P. 0.33% of their portfolio | 5.3m $1.0bn | New |
| Clearbridge Investments, LLC 0.89% of their portfolio | 5.2m $1.0bn | New |
| CAISSE DES DEPOTS ET CONSIGNATIONS 15.60% of their portfolio | 4.9m $945.9m | New |
| FIL Ltd 0.71% of their portfolio | 4.7m $910.2m | New |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.49% of their portfolio | 4.7m $914.5m | New |
| Capital Research Global Investors 0.14% of their portfolio | 4.6m $901.8m | New |
| CIBC Bancorp USA Inc. 1.17% of their portfolio | 4.6m $869.5m | First filing |
| M&G PLC 4.22% of their portfolio | 4.2m $816.8m | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.64% of their portfolio | 3.8m $745.2m | New |
| DekaBank Deutsche Girozentrale 1.23% of their portfolio | 3.8m $747.1m | New |
| CITIGROUP INC 0.46% of their portfolio | 3.7m $717.8m | New |
| Pictet Asset Management Holding SA 0.71% of their portfolio | 3.5m $675.3m | New |
| CREDIT AGRICOLE S A 1.92% of their portfolio | 3.0m $587.2m | New |
| THORNBURG INVESTMENT MANAGEMENT INC 5.77% of their portfolio | 2.9m $555.7m | New |
| Holocene Advisors, LP 1.27% of their portfolio | 2.7m $525.2m | New |
| NEUBERGER BERMAN GROUP LLC 0.39% of their portfolio | 2.6m $518.7m | New |
| Swedbank AB 0.51% of their portfolio | 2.5m $486.8m | New |
| ABN AMRO Bank N.V. 5.20% of their portfolio | 2.4m $482.2m | New |
| Lansforsakringar Fondforvaltning AB (publ) 2.48% of their portfolio | 2.4m $473.8m | New |
| ACADIAN ASSET MANAGEMENT LLC 0.65% of their portfolio | 2.3m $456.6m | New |
| NORTHERN TRUST CORP 0.06% of their portfolio | 2.3m $459.0m | New |
| ENVESTNET ASSET MANAGEMENT INC 0.12% of their portfolio | 2.3m $446.6m | New |
| BlackRock, Inc. 0.01% of their portfolio | 2.2m $440.2m | New |
| LAZARD ASSET MANAGEMENT LLC 0.71% of their portfolio | 2.2m $432.8m | New |
| NATIONAL BANK OF CANADA /FI/ 0.43% of their portfolio | 2.1m $417.6m | New |
| Boston Partners 0.43% of their portfolio | 2.1m $413.4m | New |
| Public Sector Pension Investment Board 1.29% of their portfolio | 2.1m $415.1m | New |
| Border to Coast Pensions Partnership Ltd 6.73% of their portfolio | 2.0m $398.3m | New |
| Ninety One UK Ltd 0.92% of their portfolio | 2.0m $396.5m | New |
| Capital International, Inc./CA/ 3.03% of their portfolio | 2.0m $392.7m | New |
| Russell Investments Group, Ltd. 0.42% of their portfolio | 2.0m $389.3m | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.84% of their portfolio | 2.0m $386.0m | New |
| TD Asset Management Inc 0.31% of their portfolio | 2.0m $383.4m | New |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 1.25% of their portfolio | 1.9m $377.3m | New |
| BANK OF MONTREAL /CAN/ 0.16% of their portfolio | 1.9m $379.9m | New |
| LGT Group Foundation 4.48% of their portfolio | 1.9m $367.2m | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.38% of their portfolio | 1.9m $367.7m | New |
| CITADEL ADVISORS LLC 0.26% of their portfolio | 1.9m $368.8m | New |
| Bank Julius Baer & Co. Ltd, Zurich 1.11% of their portfolio | 1.9m $367.2m | New |
| AMERICAN CENTURY COMPANIES INC 0.18% of their portfolio | 1.8m $356.4m | New |
| RAYMOND JAMES FINANCIAL INC 0.11% of their portfolio | 1.7m $342.6m | New |
| Evelyn Partners Investment Management LLP 8.84% of their portfolio | 1.7m $325.5m | New |
| WELLS FARGO & COMPANY/MN 0.06% of their portfolio | 1.5m $304.6m | New |
| CANADA LIFE ASSURANCE Co 0.53% of their portfolio | 1.5m $295.8m | New |
| MACKENZIE FINANCIAL CORP 0.34% of their portfolio | 1.4m $282.4m | New |
| Artemis Investment Management LLP 2.98% of their portfolio | 1.4m $280.6m | New |
| Korea Investment CORP 0.54% of their portfolio | 1.3m $260.6m | New |
| NATIXIS ADVISORS, LLC 0.36% of their portfolio | 1.3m $258.9m | New |
| MILLENNIUM MANAGEMENT LLC 0.19% of their portfolio | 1.3m $256.9m | New |
| Point72 Asset Management, L.P. 0.42% of their portfolio | 1.2m $243.4m | New |
| Intesa Sanpaolo S.p.A. 14.18% of their portfolio | 1.2m $226.3m | New |
| Alyeska Investment Group, L.P. 0.59% of their portfolio | 1.1m $209.5m | New |
| JONES FINANCIAL COMPANIES LLLP 0.09% of their portfolio | 1.0m $189.3m | New |
| Groupe la Francaise 2.66% of their portfolio | 984.6k $190.8m | New |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.60% of their portfolio | 957.0k $186.1m | New |
| Generali Asset Management SPA SGR 2.93% of their portfolio | 954.8k $140.3m | New |
| Assenagon Asset Management S.A. 0.29% of their portfolio | 929.3k $182.8m | New |
| CAPITAL INTERNATIONAL SARL 2.92% of their portfolio | 914.8k $178.3m | New |
| MUFG Securities EMEA plc 2.50% of their portfolio | 864.0k $167.9m | New |
| GROUPAMA ASSET MANAGMENT 1.85% of their portfolio | 863.6k $126.9m | New |
| JANE STREET GROUP, LLC 0.18% of their portfolio | 844.7k $166.6m | New |
| ASR Vermogensbeheer N.V. 1.92% of their portfolio | 841.9k $163.1m | New |
| Allspring Global Investments Holdings, LLC 0.28% of their portfolio | 828.4k $166.0m | New |