Vault-13

ZYMEWORKS INC ZYME

COM · Common Stock · CUSIP 98985W102

3 institutional holders -87 vs Q3 2022
2,070,9872.1m shares reported held*
$16.3mreported value*
0 new 1 added 0 reduced 85 sold out net sold ≈ $356.2m (-45.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $7.86.

Trends to Q4 2022

Institutional holders

Managers reporting a position, each quarter

050100Q3 22: 90Q4 22: 33Q3 22Q4 22
Numbers
QuarterHolders
Q3 202290
Q4 20223

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500k$1m$1.5m$2mQ3 22 calls: $1.6mQ3 22 puts: $519.0kQ3 22P/C 0.33Q4 22 calls: $0Q4 22 puts: $0Q4 22P/C —
Numbers
QuarterCallsPutsP/C
Q3 2022$1.6m$519.0k0.33
Q4 2022$0$0—

Biggest buyers

SAMSARA BIOCAPITAL, LLC Added +649,700+649.7k

Biggest sellers

ARMISTICE CAPITAL, LLC Sold out -5,785,000-5.8m
Redmile Group, LLC Sold out -5,765,818-5.8m
EVENTIDE ASSET MANAGEMENT, LLC Sold out -5,380,200-5.4m
MORGAN STANLEY Sold out -5,258,975-5.3m
PERCEPTIVE ADVISORS LLC Sold out -4,400,099-4.4m
Camber Capital Management LP Sold out -2,865,000-2.9m
CREDIT SUISSE AG/ Sold out -2,440,372-2.4m
BAKER BROS. ADVISORS LP Sold out -1,708,472-1.7m
Woodline Partners LP Sold out -1,554,082-1.6m
BNP PARIBAS ASSET MANAGEMENT Holding S.A. Sold out -1,509,037-1.5m

Insider purchases and sales in Q4 2022

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
202Q1 21: 0 buyingQ1 21: 0 sellingQ2 21: 0 buyingQ2 21: 0 sellingQ2 21Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 0 buyingQ4 21: 0 sellingQ4 21Q1 22: 0 buyingQ1 22: 0 sellingQ2 22: 0 buyingQ2 22: 0 sellingQ2 22Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 0 buyingQ4 22: 2 sellingQ4 22
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q1 20210—0——
Q2 20210—0——
Q3 20210—0——
Q4 20210—0——
Q1 20220—0——
Q2 20220—0——
Q3 20220—0——
Q4 20220—2$25.4k—
DateInsiderTradeSharesPrice ValueTheir holding
2022-12-12 Astle Christopher SVP & Chief Financial Officer Sold 887 $6.01 $5.3k887 shares -40%
2022-11-10 Josephson Neil Chief Medical Officer Sold 2,475 $8.10 $20.0k2.5k shares -15%
2022-10-13 Redmile Group, LLC +1 10% owner · See Footnote Bought 30,481 $5.03 $153.3k30.5k shares +0%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q4 2022

#ManagerLocationShares Value% of their portfolioChangeShares change
1 SAMSARA BIOCAPITAL, LLC 2.74% of their portfolio PALO ALTO, CA 1,620,6871.6m $12.7m $12.7m 2.74% Added +649.7k +649,700
2 Artal Group S.A. 0.20% of their portfolio LUXEMBOURG, N4 450,000450.0k $3.5m $3.5m 0.20% Unchanged
3 IFP Advisors, Inc 0.00% of their portfolio TAMPA, FL 300300 $7.0k $7.0k 0.00% Unchanged