ZENTALIS PHARMACEUTICALS INC ZNTL
COM · Common Stock · CUSIP 98943L107
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.3m this quarter). Holder counts are more reliable. Shares outstanding: 70.8m as of 2023-11-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $20.06. Options: 8 managers hold calls ($4.8m notional), 6 hold puts ($906.4k).
Trends to Q3 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 120 |
| Q4 2022 | 105 |
| Q1 2023 | 110 |
| Q2 2023 | 134 |
| Q3 2023 | 137 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 51 | 51 |
| Q1 2023 | 53 | 43 |
| Q2 2023 | 92 | 38 |
| Q3 2023 | 69 | 52 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2022 | $1.6m | $24.2k | 0.02 |
| Q1 2023 | $608.0k | $471.3k | 0.78 |
| Q2 2023 | $4.4m | $1.1m | 0.24 |
| Q3 2023 | $4.8m | $906.4k | 0.19 |
Biggest buyers
| EVENTIDE ASSET MANAGEMENT, LLC | Added | +936.2k |
| BlackRock Inc. | Added | +445.1k |
| Sofinnova Investments, Inc. | Added | +383.6k |
| VANGUARD GROUP INC | Added | +307.5k |
| MILLENNIUM MANAGEMENT LLC | Added | +258.6k |
| SECTORAL ASSET MANAGEMENT INC | Added | +152.5k |
| Qube Research & Technologies Ltd | New | +141.4k |
| TWINBEECH CAPITAL LP | New | +128.9k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +119.2k |
| DIMENSIONAL FUND ADVISORS LP | Added | +110.4k |
Biggest sellers
| ALLIANCEBERNSTEIN L.P. | Reduced | -1.3m |
| FMR LLC | Reduced | -1.1m |
| GOLDMAN SACHS GROUP INC | Reduced | -510.3k |
| STATE STREET CORP | Reduced | -449.6k |
| Cormorant Asset Management, LP | Reduced | -395.0k |
| DEUTSCHE BANK AG\ | Reduced | -387.1k |
| Deep Track Capital, LP | Sold out | -300.3k |
| EcoR1 Capital, LLC | Sold out | -300.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -253.3k |
| MARSHALL WACE, LLP | Reduced | -245.2k |
Biggest calls
| MILLENNIUM MANAGEMENT LLC | Added | $1.9m95.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.4m71.8k shares |
| JANE STREET GROUP, LLC | Reduced | $475.4k23.7k shares |
| GTS SECURITIES LLC | New | $411.2k20.5k shares |
| CITADEL ADVISORS LLC | Reduced | $246.7k12.3k shares |
| SIMPLEX TRADING, LLC | Added | $240.0k12.0k shares |
| GROUP ONE TRADING LLC | Reduced | $90.3k4.5k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $349.0k17.4k shares |
| CITADEL ADVISORS LLC | Added | $226.7k11.3k shares |
| GTS SECURITIES LLC | New | $220.7k11.0k shares |
| SIMPLEX TRADING, LLC | Added | $108.0k5.4k shares |
| GROUP ONE TRADING LLC | Unchanged | $2.0k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| WALTERS GROUP 13G · passive investor -0.9 pts · filed 2026-08-19 | 18.8% |
| Walters William T 13G · passive investor +0.8 pts · filed 2025-01-31 | 9.9% |
| 5AM Opportunities II (GP), LLC 13G · passive investor new · filed 2025-12-30 | 6.4% |
| Squadron Capital Management LLC 13G · passive investor new · filed 2026-03-03 | 5.1% |
Fell to 5% or below in the last year: BlackRock, Inc. (4.1%, 2026-10-27), BARCLAYS PLC (3.2%, 2026-08-13), Matrix Capital Management Company, LP (0.0%, 2026-01-02)
Insider purchases and sales in Q3 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2021 | 0 | — | 6 | $14.2m | — |
| Q1 2022 | 0 | — | 7 | $10.1m | — |
| Q2 2022 | 0 | — | 4 | $2.6m | — |
| Q3 2022 | 0 | — | 2 | $1.8m | — |
| Q4 2022 | 0 | — | 1 | $1.7m | — |
| Q1 2023 | 0 | — | 3 | $1.3m | — |
| Q2 2023 | 0 | — | 2 | $3.1m | $3.1m |
| Q3 2023 | 0 | — | 1 | $125.2k | $125.2k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-09-11 | Skvarka Jan Director | Sold plan | $125.2k5.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2023
| Manager | Shares | Change |
|---|---|---|
| Matrix Capital Management Company, LP 3.36% of their portfolio | 14.0m $280.0m | Unchanged |
| FMR LLC 0.02% of their portfolio | 9.5m $190.4m | Reduced -1.1m |
| EVENTIDE ASSET MANAGEMENT, LLC 2.82% of their portfolio | 7.8m $156.7m | Added +936.2k |
| VANGUARD GROUP INC 0.00% of their portfolio | 5.2m $105.0m | Added +307.5k |
| BlackRock Inc. 0.00% of their portfolio | 4.4m $88.2m | Added +445.1k |
| Capital International Investors 0.02% of their portfolio | 3.1m $62.7m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 2.7m $54.5m | Added +31.2k |
| STATE STREET CORP 0.00% of their portfolio | 2.7m $54.2m | Reduced -449.6k |
| CITADEL ADVISORS LLC 0.05% of their portfolio | 2.2m $43.2m | Added +26.1k |
| Avidity Partners Management LP 1.70% of their portfolio | 2.1m $42.1m | Reduced -234.0k |
| Decheng Capital Management III (Cayman), LLC 14.06% of their portfolio | 2.1m $42.1m | Unchanged |
| T. Rowe Price Investment Management, Inc. 0.03% of their portfolio | 2.0m $39.6m | Reduced -26.9k |
| FEDERATED HERMES, INC. 0.10% of their portfolio | 1.9m $39.1m | Reduced -70.5k |
| WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio | 1.9m $38.5m | Added +8.7k |
| Sofinnova Investments, Inc. 1.71% of their portfolio | 1.2m $24.3m | Added +383.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.2m $23.8m | Added +119.2k |
| PRIMECAP MANAGEMENT CO/CA/ 0.02% of their portfolio | 1.0m $20.7m | Reduced -77.4k |
| Woodline Partners LP 0.24% of their portfolio | 1.0m $20.1m | Reduced -95.0k |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD 2.69% of their portfolio | 961.5k $19.3m | Unchanged |
| First Light Asset Management, LLC 1.62% of their portfolio | 848.5k $17.0m | Added +90.6k |
| Cormorant Asset Management, LP 0.82% of their portfolio | 700.0k $14.0m | Reduced -395.0k |
| Capital World Investors 0.00% of their portfolio | 683.0k $13.7m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 545.6k $10.9m | Added +42.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 540.7k $10.8m | Added +61.9k |
| Verition Fund Management LLC 0.14% of their portfolio | 537.4k $10.8m | Added +30.3k |
| 5AM Venture Management, LLC 2.83% of their portfolio | 490.0k $9.8m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 484.3k $9.7m | Added +110.4k |
| Boxer Capital, LLC 0.48% of their portfolio | 450.0k $9.0m | Unchanged |
| Integral Health Asset Management, LLC 1.28% of their portfolio | 450.0k $9.0m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 446.9k $9.0m | Added +258.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 442.1k $8.9m | Added +36.2k |
| SECTORAL ASSET MANAGEMENT INC 1.51% of their portfolio | 386.5k $7.8m | Added +152.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 301.7k $6.1m | Reduced -253.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 285.4k $5.7m | Added +75.0k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 270.8k $5.4m | Reduced -245.2k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 249.1k $5.0m | Added +20.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 242.1k $4.9m | Added +77.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 233.0k $4.7m | Reduced -32.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 223.3k $4.5m | Reduced -510.3k |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 200.7k $4.0m | Reduced -50.3k |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 194.9k $3.9m | Unchanged |
| Mayo Clinic 7.23% of their portfolio | 187.1k $3.8m | Unchanged |
| TD Asset Management Inc 0.00% of their portfolio | 180.8k $3.6m | Added +78.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 166.0k $3.3m | Reduced -36.7k |
| NORGES BANK 0.00% of their portfolio | 164.3k $3.3m | Reduced -3.4k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.08% of their portfolio | 156.5k $3.1m | Added +4.2k |
| SG Americas Securities, LLC 0.04% of their portfolio | 146.5k $2.9m | Added +72.9k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 141.4k $2.8m | New |
| Invesco Ltd. 0.00% of their portfolio | 136.6k $2.7m | Added +6.3k |
| TWINBEECH CAPITAL LP 0.05% of their portfolio | 128.9k $2.6m | New |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 128.2k $2.6m | Added +10.8k |
| BARCLAYS PLC 0.00% of their portfolio | 110.8k $2.2m | Reduced -101.6k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 110.1k $2.2m | Added +3.8k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 109.4k $2.2m | Added +92.7k |
| Swiss National Bank 0.00% of their portfolio | 108.4k $2.2m | Reduced -14.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 101.9k $2.0m | Reduced -8.8k |
| Ghost Tree Capital, LLC 0.97% of their portfolio | 100.0k $2.0m | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 99.4k $2.0m | Reduced -6.5k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 90.4k $1.8m | Added +8.8k |
| ArrowMark Colorado Holdings LLC 0.02% of their portfolio | 87.6k $1.8m | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 85.2k $1.7m | Reduced -202 |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 80.9k $1.6m | Added +14.1k |
| UBS Group AG 0.00% of their portfolio | 66.8k $1.3m | Reduced -22.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 57.7k $1.2m | Reduced -1.3m |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 56.4k $1.1m | Reduced -9.5k |
| Legal & General Group Plc 0.00% of their portfolio | 55.8k $1.1m | Added +854 |
| ALPS ADVISORS INC 0.01% of their portfolio | 52.1k $1.0m | Added +8.4k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 50.3k $1.0m | Reduced -9.5k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 50.3k $1.0m | Reduced -15.0k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.00% of their portfolio | 47.0k $942.8k | Added +30.0k |
| Squarepoint Ops LLC 0.00% of their portfolio | 45.5k $912.2k | Reduced -34.6k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 43.5k $871.8k | Reduced -22.7k |
| Values First Advisors, Inc. 0.53% of their portfolio | 40.9k $820.9k | Added +10.4k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 39.3k $787.9k | Added +14.9k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 37.4k $751.0k | New |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 35.2k $706.6k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 34.7k $695.2k | Added +4.3k |
| PROFUND ADVISORS LLC 0.04% of their portfolio | 34.2k $685.6k | Reduced -11.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 32.1k $643.5k | Reduced -387.1k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 30.7k $615.9k | Added +5.2k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 30.2k $605.0k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 29.9k $600.0k | Unchanged |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 29.1k $583.0k | Added +5.4k |
| Trexquant Investment LP 0.01% of their portfolio | 24.5k $491.8k | Reduced -15.9k |
| GSA CAPITAL PARTNERS LLP 0.04% of their portfolio | 24.3k $488.0k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 24.3k $488.2k | Added +9.6k |
| Engineers Gate Manager LP 0.02% of their portfolio | 22.6k $453.6k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 22.0k $441.6k | Added +250 |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 21.5k $431.1k | Added +11 |
| XTX Topco Ltd 0.07% of their portfolio | 19.0k $381.3k | New |
| Allianz Asset Management GmbH 0.00% of their portfolio | 18.8k $377.1k | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 17.0k $341.0k | Added +6.7k |
| EVERGREEN CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 16.9k $339.3k | Unchanged |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 16.6k $333.4k | Added +2.7k |
| Virtu Financial LLC 0.03% of their portfolio | 16.2k $325.0k | New |
| Regency Capital Management Inc.\DE 0.26% of their portfolio | 15.0k $300.9k | New |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 14.9k $298.9k | New |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 14.6k $293.7k | Added +559 |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 14.0k $281.8k | Added +2.4k |
| TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio | 14.0k $281.0k | Reduced -1.2k |