XILIO THERAPEUTICS INC
COM · CUSIP 98422T100
36
institutional holders
+0 vs Q2 2025
22.1m
shares reported held*
$18.6mreported value*
4 new
6 added
4 reduced
3 sold out
net sold ≈ $1.5m (-1.7m shares)
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.84.
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 30 |
| Q4 2022 | 29 |
| Q1 2023 | 33 |
| Q2 2023 | 33 |
| Q3 2023 | 32 |
| Q4 2023 | 35 |
| Q1 2024 | 32 |
| Q2 2024 | 33 |
| Q3 2024 | 34 |
| Q4 2024 | 36 |
| Q1 2025 | 36 |
| Q2 2025 | 36 |
| Q3 2025 | 36 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Bought or addedCut or sold out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 13 | 7 |
| Q1 2024 | 11 | 13 |
| Q2 2024 | 16 | 12 |
| Q3 2024 | 13 | 8 |
| Q4 2024 | 10 | 11 |
| Q1 2025 | 14 | 13 |
| Q2 2025 | 9 | 16 |
| Q3 2025 | 10 | 7 |
Biggest buyers
| STATE STREET CORP | Added | +120.5k |
| VANGUARD GROUP INC | Added | +104.7k |
| Squarepoint Ops LLC | Added | +93.3k |
| XTX Topco Ltd | Added | +41.3k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +40.5k |
| TWO SIGMA SECURITIES, LLC | New | +32.1k |
| TWO SIGMA ADVISERS, LP | New | +29.7k |
| HRT FINANCIAL LP | New | +24.7k |
| TWO SIGMA INVESTMENTS, LP | Added | +9.8k |
| CITIGROUP INC | New | +258 |
Biggest sellers
| Ghisallo Capital Management LLC | Sold out | -1.3m |
| MORGAN STANLEY | Reduced | -482.4k |
| UBS Group AG | Reduced | -226.3k |
| Avantax Planning Partners, Inc. | Sold out | -142.3k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -40.7k |
| Tower Research Capital LLC (TRC) | Sold out | -15.4k |
| BANK OF AMERICA CORP /DE/ | Reduced | -85 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| GILEAD SCIENCES, INC. 13G · passive investor no change · filed 2026-02-12 | 19.9% |
| Coastlands Capital LP 13G · institution new · filed 2025-12-11 | 10.0% |
| Sirenia Capital Management LP 13G · institution new · filed 2026-05-15 | 9.9% |
| AbbVie Inc. 13G · passive investor new · filed 2025-02-18 | 9.0% |
| Bain Capital Life Sciences Fund II, L.P. 13G · passive investor filed 2026-02-17 | 8.5% |
| STEMPOINT CAPITAL LP 13G · institution +1.2 pts · filed 2026-02-17 | 8.4% |
| Frazier Life Sciences Public Fund, L.P. 13G · passive investor -3.2 pts · filed 2026-02-13 | 6.7% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15)
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| GILEAD SCIENCES, INC. 0.43% of their portfolio | 9.1m $7.7m | Unchanged |
| Bain Capital Life Sciences Investors, LLC 0.26% of their portfolio | 4.6m $3.8m | Unchanged |
| Merck & Co., Inc. 0.57% of their portfolio | 1.5m $1.3m | Unchanged |
| TAKEDA PHARMACEUTICAL CO LTD 7.59% of their portfolio | 1.5m $1.2m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.3m $1.1m | Added +104.7k |
| MORGAN STANLEY 0.00% of their portfolio | 961.9k $810.6k | Reduced -482.4k |
| AJU IB Investment Co., Ltd. 0.52% of their portfolio | 667.7k $595.6k | Unchanged |
| FMR LLC 0.00% of their portfolio | 511.8k $431.3k | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 329.0k $277.3k | Reduced -40.7k |
| Squarepoint Ops LLC 0.00% of their portfolio | 328.8k $277.1k | Added +93.3k |
| Trustees of Columbia University in the City of New York 0.03% of their portfolio | 249.6k $210.4k | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 204.7k $172.5k | Added +40.5k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 198.9k $167.6k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 163.9k $138.1k | Added +120.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 87.8k $74.0k | Added +9.8k |
| XTX Topco Ltd 0.00% of their portfolio | 76.0k $64.1k | Added +41.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 66.6k $56.1k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 56.1k $47.3k | Unchanged |
| TWO SIGMA SECURITIES, LLC 0.00% of their portfolio | 32.1k $27.1k | New |
| LPL Financial LLC 0.00% of their portfolio | 31.0k $26.1k | Unchanged |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 29.7k $25.0k | New |
| Mariner, LLC 0.00% of their portfolio | 25.0k $21.1k | Unchanged |
| Aptus Capital Advisors, LLC 0.00% of their portfolio | 25.0k $21.1k | Unchanged |
| SevenBridge Financial Group, LLC 0.00% of their portfolio | 25.0k $19.3k | Unchanged |
| HRT FINANCIAL LP 0.00% of their portfolio | 24.7k $20.0k | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 18.8k $15.8k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 13.7k $11.5k | Reduced -226.3k |
| Dunhill Financial, LLC 0.00% of their portfolio | 10.3k $8.7k | Unchanged |
| INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV 0.00% of their portfolio | 10.0k $8.4k | Unchanged |
| Pinnacle Financial Group, LLC / IL 0.00% of their portfolio | 10.0k $8.4k | Unchanged |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 3.3k $2.8k | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 2.0k $1.7k | Unchanged |
| Key Financial Inc 0.00% of their portfolio | 830 $691 | Unchanged |
| Private Wealth Management Group, LLC 0.00% of their portfolio | 310 $262 | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 258 $217 | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 246 $207 | Reduced -85 |