VOR BIOPHARMA INC VOR
COM NEW · Common Stock · CUSIP 929033207
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($38.6k this quarter). Holder counts are more reliable. Shares outstanding: 48.8m as of 2026-03-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $17.72. Options: 1 managers hold calls ($918.8k notional), 2 hold puts ($3.4m).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2025 | 1 |
| Q2 2025 | 1 |
| Q3 2025 | 36 |
| Q4 2025 | 55 |
| Q1 2026 | 80 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2025 | 0 | 0 |
| Q3 2025 | 36 | 1 |
| Q4 2025 | 47 | 12 |
| Q1 2026 | 58 | 18 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $0 | $0 | — |
| Q3 2025 | $360.9m | $57.8m | 0.16 |
| Q4 2025 | $16.2m | $5.9m | 0.37 |
| Q1 2026 | $918.8k | $3.4m | 3.71 |
Biggest buyers
| TCG Crossover Management, LLC | New | +5.7m |
| MARSHALL WACE, LLP | New | +1.2m |
| Venrock Adviser, LLC | Added | +1.1m |
| STATE STREET CORP | Added | +1.0m |
| Caligan Partners LP | Added | +1,000.0k |
| Rosalind Advisors, Inc. | New | +700.0k |
| Logos Global Management LP | Added | +650.0k |
| BOOTHBAY FUND MANAGEMENT, LLC | New | +555.7k |
| FCPM III SERVICES B.V. | Added | +500.0k |
| BRAIDWELL LP | New | +466.8k |
Biggest sellers
| FMR LLC | Reduced | -986.5k |
| CITADEL ADVISORS LLC | Reduced | -285.1k |
| FINDELL CAPITAL MANAGEMENT LLC | Sold out | -231.0k |
| AMERIPRISE FINANCIAL INC | Sold out | -163.1k |
| SPHERA FUNDS MANAGEMENT LTD. | Reduced | -88.5k |
| OMERS ADMINISTRATION Corp | Sold out | -20.7k |
| XTX Topco Ltd | Sold out | -17.5k |
| JANE STREET GROUP, LLC | Reduced | -15.9k |
| TUDOR INVESTMENT CORP ET AL | Reduced | -15.1k |
| Persistent Asset Partners Ltd | Sold out | -10.8k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $918.8k51.5k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $3.1m176.2k shares |
| GROUP ONE TRADING LLC | Reduced | $265.8k14.9k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
no change · filed 2026-07-21
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: Effective July 6, 2026, Andrew Levin resigned from the Board of Directors of the Issuer. Full filing |
19.9% |
Reprogrammed Interchange LLC
13D · may seek influence
filed 2025-10-17
Stated purposeItem 4 of Schedule 13D is hereby amended and supplemented as follows: From October 15, 2025 through October 16, 2025, Reprogrammed Interchange LLC sold the following shares of Vor Biopharma Inc. in open market transactions, resulting in a decrease in the number of shares of Common Stock beneficially owned by the Reporting Persons by more than one percent of the outstanding shares of Common Stock of the Issuer. 1. 71,655 shares on October 15, 2025, at a weighted average per share sale price of $31.9196. 2. 2,021 shares on October 16, 2025, at a weighted average per share sale price of $30.4548. Full filing |
17.6% |
| FMR LLC 13G · institution +2.9 pts · filed 2026-08-07 | 12.0% |
| TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-04-01 | 10.5% |
ForGrowth III PA B.V.
13D · may seek influence
no change · filed 2025-12-23
Stated purposeThe Reporting Persons acquired their shares of Common Stock as an investment in the ordinary course of business. On December 18, 2025, Wouter Joustra, a General Partner at Forbion Capital, was appointed to the Issuer's board of directors. The Reporting Persons, either directly or indirectly through Mr. Joustra, may engage in discussions from time to time with the Issuer's board of directors, the Issuer's management or the Issuer's other stockholders. These discussions may be with respect to (i) acquiring or disposing of the shares or other securities of the Issuer; (ii) maintaining or changing the Issuer's business, operations, governance, management, strategy or capitalization; or (iii) implementing transactions that may relate to or may result in any matter set forth in paragraphs (a) t… Full filing |
10.0% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor no change · filed 2026-08-14 | 9.9% |
| Verve Capital Ltd 13G · passive investor -3.0 pts · filed 2026-08-13 | 6.3% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-30 | 5.7% |
Fell to 5% or below in the last year: Frazier Life Sciences Public Fund, L.P. (4.2%, 2026-08-14), Qiming Venture Partners VIII-HC, L.P. (2.0%, 2026-05-06), GREAT POINT PARTNERS LLC (3.3%, 2026-02-17), Paradigm Biocapital Advisors LP (4.5%, 2026-02-17)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 1 | $20.4k | $20.4k |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 1 | $12.9k | $12.9k |
| Q1 2025 | 0 | — | 1 | $6.7k | $6.7k |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $33.7m | — |
| Q1 2026 | 0 | — | 0 | — | — |
None reported in Q1 2026.
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| TCG Crossover Management, LLC 2.76% of their portfolio | 5.7m $96.5m | New |
| RA CAPITAL MANAGEMENT, L.P. 1.02% of their portfolio | 5.4m $96.4m | Unchanged |
| FCPM III SERVICES B.V. 10.17% of their portfolio | 4.1m $73.5m | Added +500.0k |
| Venrock Adviser, LLC 2.03% of their portfolio | 3.0m $54.3m | Added +1.1m |
| Frazier Life Sciences Management, L.P. 1.17% of their portfolio | 2.5m $45.4m | Unchanged |
| Caligan Partners LP 2.43% of their portfolio | 1.9m $34.3m | Added +1,000.0k |
| GREAT POINT PARTNERS LLC 7.65% of their portfolio | 1.8m $31.2m | Added +379.9k |
| Paradigm Biocapital Advisors LP 0.64% of their portfolio | 1.8m $31.2m | Unchanged |
| FMR LLC 0.00% of their portfolio | 1.5m $27.5m | Reduced -986.5k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.4m $25.6m | First filing |
| MARSHALL WACE, LLP 0.02% of their portfolio | 1.2m $20.6m | New |
| STATE STREET CORP 0.00% of their portfolio | 1.1m $20.0m | Added +1.0m |
| NEXTBio Capital Management LP 8.28% of their portfolio | 1,000.0k $17.8m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 794.8k $14.2m | Added +329.1k |
| Logos Global Management LP 0.69% of their portfolio | 750.0k $13.4m | Added +650.0k |
| Rosalind Advisors, Inc. 5.12% of their portfolio | 700.0k $12.5m | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.23% of their portfolio | 555.7k $9.9m | New |
| UBS Group AG 0.00% of their portfolio | 488.4k $8.7m | Added +196.2k |
| BRAIDWELL LP 0.28% of their portfolio | 466.8k $8.3m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 342.6k $6.1m | Added +156.8k |
| Clearline Capital LP 0.45% of their portfolio | 326.2k $5.8m | New |
| SPHERA FUNDS MANAGEMENT LTD. 0.99% of their portfolio | 321.9k $5.7m | Reduced -88.5k |
| Laurion Capital Management LP 0.53% of their portfolio | 318.7k $5.7m | Added +1.4k |
| Propel Bio Management, LLC 3.52% of their portfolio | 314.5k $5.6m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 261.9k $4.7m | Added +116.3k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 258.6k $4.6m | Added +34.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 232.6k $4.1m | Added +217.8k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 185.5k $3.3m | First filing |
| Jump Financial, LLC 0.05% of their portfolio | 173.0k $3.1m | New |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 152.6k $2.7m | Reduced -15.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 148.8k $2.7m | Reduced -285.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 128.8k $2.3m | New |
| MORGAN STANLEY 0.00% of their portfolio | 116.7k $2.1m | Added +88.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 112.9k $2.0m | Added +112.5k |
| AXIOM INVESTORS LLC /DE 0.02% of their portfolio | 95.7k $1.7m | New |
| Quadrature Capital Ltd 0.02% of their portfolio | 76.6k $1.4m | Added +49.8k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 75.9k $1.4m | Reduced -15.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 64.5k $1.2m | Added +25.6k |
| JOHNSON & JOHNSON 0.15% of their portfolio | 53.7k $958.6k | Unchanged |
| Simplify Asset Management Inc. 0.01% of their portfolio | 53.5k $954.6k | New |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 50.5k $901.0k | New |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 42.2k $753.2k | New |
| Irenic Capital Management LP 0.05% of their portfolio | 32.7k $582.7k | New |
| Engineers Gate Manager LP 0.01% of their portfolio | 26.9k $479.5k | Reduced -1.3k |
| Squarepoint Ops LLC 0.00% of their portfolio | 25.5k $454.6k | Added +7.0k |
| Sarissa Capital Management LP 0.29% of their portfolio | 25.4k $453.1k | Unchanged |
| Bollard Group LLC 0.01% of their portfolio | 24.0k $428.0k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 22.2k $396.3k | New |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 22.0k $392.7k | New |
| Scientech Research LLC 0.22% of their portfolio | 15.0k $268.4k | New |
| AXQ CAPITAL, LP 0.03% of their portfolio | 15.0k $267.9k | New |
| INDEPENDENT FINANCIAL GROUP, LLC 0.01% of their portfolio | 14.0k $249.3k | Reduced -3.0k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 13.7k $244.5k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 12.9k $229.7k | First filing |
| WINTON GROUP Ltd 0.01% of their portfolio | 11.9k $211.8k | New |
| Cannon Global Investment Management, LLC 0.51% of their portfolio | 11.7k $208.7k | New |
| Invesco Ltd. 0.00% of their portfolio | 11.6k $206.9k | New |
| Diametric Capital, LP 0.05% of their portfolio | 10.1k $179.6k | New |
| GROUP ONE TRADING LLC 0.01% of their portfolio | 9.1k $161.7k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 7.4k $131.4k | Added +4.6k |
| CITIGROUP INC 0.00% of their portfolio | 5.4k $95.9k | Reduced -967 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 4.4k $64.2k | Added +2.1k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 3.5k $51.6k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 3.5k $61.8k | Added +1.7k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 2.8k $50.7k | Added +2.6k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 2.2k $38.6k | Added +1.3k |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 372 $6.6k | Added +42 |
| Quantbot Technologies LP 0.00% of their portfolio | 307 $5.5k | New |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 246 $4.4k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 199 $4.0k | Added +192 |
| BARCLAYS PLC 0.00% of their portfolio | 136 $2.4k | Reduced -1.3k |
| Allworth Financial LP 0.00% of their portfolio | 73 $1.3k | Added +70 |
| Parallel Advisors, LLC 0.00% of their portfolio | 48 $856 | New |
| MAI Capital Management 0.00% of their portfolio | 40 $714 | Unchanged |
| SIGNATUREFD, LLC 0.00% of their portfolio | 39 $696 | New |
| Ameritas Advisory Services, LLC 0.00% of their portfolio | 37 $660 | New |
| Fortitude Family Office, LLC 0.00% of their portfolio | 31 $553 | New |
| WPG Advisers, LLC 0.00% of their portfolio | 21 $375 | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 3 $54 | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1 $18 | Unchanged |