Vault-13

VOR BIOPHARMA INC VOR

COM NEW · Common Stock · CUSIP 929033207

80 institutional holders +25 vs Q4 2025
40,446,53340.4m shares reported held*
82.8% of all shares outstanding*
$716.8mreported value*
32 new 26 added 9 reduced 9 sold out net bought ≈ $250.5m (+14.0m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($38.6k this quarter). Holder counts are more reliable. Shares outstanding: 48.8m as of 2026-03-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $17.72. Options: 1 managers hold calls ($918.8k notional), 2 hold puts ($3.4m).

Trends to Q1 2026

Institutional holders

Managers reporting a position, each quarter

050100Q1 25: 1Q2 25: 1Q3 25: 36Q4 25: 55Q1 26: 8080Q1 25Q2 25Q3 25Q4 25Q1 26
Numbers
QuarterHolders
Q1 20251
Q2 20251
Q3 202536
Q4 202555
Q1 202680

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q2 25: 0 bought or addedQ2 25: 0 cut or sold outQ2 25Q3 25: 36 bought or addedQ3 25: 1 cut or sold outQ3 25Q4 25: 47 bought or addedQ4 25: 12 cut or sold outQ4 25Q1 26: 58 bought or addedQ1 26: 18 cut or sold outQ1 26
Numbers
QuarterBought or addedCut or sold out
Q2 202500
Q3 2025361
Q4 20254712
Q1 20265818

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$100m$200m$300m$400mQ2 25 calls: $0Q2 25 puts: $0Q2 25P/C —Q3 25 calls: $360.9mQ3 25 puts: $57.8mQ3 25P/C 0.16Q4 25 calls: $16.2mQ4 25 puts: $5.9mQ4 25P/C 0.37Q1 26 calls: $918.8kQ1 26 puts: $3.4mQ1 26P/C 3.71
Numbers
QuarterCallsPutsP/C
Q2 2025$0$0—
Q3 2025$360.9m$57.8m0.16
Q4 2025$16.2m$5.9m0.37
Q1 2026$918.8k$3.4m3.71

Biggest buyers

TCG Crossover Management, LLC New +5,673,078+5.7m
MARSHALL WACE, LLP New +1,153,276+1.2m
Venrock Adviser, LLC Added +1,097,953+1.1m
STATE STREET CORP Added +1,027,405+1.0m
Caligan Partners LP Added +999,999+1,000.0k
Rosalind Advisors, Inc. New +700,000+700.0k
Logos Global Management LP Added +650,000+650.0k
BOOTHBAY FUND MANAGEMENT, LLC New +555,702+555.7k
FCPM III SERVICES B.V. Added +500,000+500.0k
BRAIDWELL LP New +466,774+466.8k

Biggest sellers

FMR LLC Reduced -986,500-986.5k
CITADEL ADVISORS LLC Reduced -285,126-285.1k
FINDELL CAPITAL MANAGEMENT LLC Sold out -231,000-231.0k
AMERIPRISE FINANCIAL INC Sold out -163,061-163.1k
SPHERA FUNDS MANAGEMENT LTD. Reduced -88,500-88.5k
OMERS ADMINISTRATION Corp Sold out -20,700-20.7k
XTX Topco Ltd Sold out -17,542-17.5k
JANE STREET GROUP, LLC Reduced -15,920-15.9k
TUDOR INVESTMENT CORP ET AL Reduced -15,102-15.1k
Persistent Asset Partners Ltd Sold out -10,798-10.8k

Biggest calls

GROUP ONE TRADING LLC Reduced $918.8k51.5k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $3.1m176.2k shares
GROUP ONE TRADING LLC Reduced $265.8k14.9k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence no change · filed 2026-07-21
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: Effective July 6, 2026, Andrew Levin resigned from the Board of Directors of the Issuer. Full filing
19.9% no change 12.9m≈ $238.2m 2026-07-21
Reprogrammed Interchange LLC 13D · may seek influence filed 2025-10-17
Stated purposeItem 4 of Schedule 13D is hereby amended and supplemented as follows: From October 15, 2025 through October 16, 2025, Reprogrammed Interchange LLC sold the following shares of Vor Biopharma Inc. in open market transactions, resulting in a decrease in the number of shares of Common Stock beneficially owned by the Reporting Persons by more than one percent of the outstanding shares of Common Stock of the Issuer. 1. 71,655 shares on October 15, 2025, at a weighted average per share sale price of $31.9196. 2. 2,021 shares on October 16, 2025, at a weighted average per share sale price of $30.4548. Full filing
17.6% 1.2m≈ $22.2m 2025-10-17
FMR LLC 13G · institution +2.9 pts · filed 2026-08-07 12.0% +2.9 pts 6.5m≈ $119.8m 2026-08-07
TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-04-01 10.5% new 5.7m≈ $104.4m 2026-04-01
ForGrowth III PA B.V. 13D · may seek influence no change · filed 2025-12-23
Stated purposeThe Reporting Persons acquired their shares of Common Stock as an investment in the ordinary course of business. On December 18, 2025, Wouter Joustra, a General Partner at Forbion Capital, was appointed to the Issuer's board of directors. The Reporting Persons, either directly or indirectly through Mr. Joustra, may engage in discussions from time to time with the Issuer's board of directors, the Issuer's management or the Issuer's other stockholders. These discussions may be with respect to (i) acquiring or disposing of the shares or other securities of the Issuer; (ii) maintaining or changing the Issuer's business, operations, governance, management, strategy or capitalization; or (iii) implementing transactions that may relate to or may result in any matter set forth in paragraphs (a) t… Full filing
10.0% no change 10.2m≈ $119.7m 2025-12-23
Venrock Healthcare Capital Partners III, L.P. 13G · passive investor no change · filed 2026-08-14 9.9% no change 5.7m≈ $104.5m 2026-08-14
Verve Capital Ltd 13G · passive investor -3.0 pts · filed 2026-08-13 6.3% -3.0 pts 3.4m≈ $62.8m 2026-08-13
BlackRock, Inc. 13G · institution new · filed 2026-07-30 5.7% new 3.1m≈ $57.1m 2026-07-30

Fell to 5% or below in the last year: Frazier Life Sciences Public Fund, L.P. (4.2%, 2026-08-14), Qiming Venture Partners VIII-HC, L.P. (2.0%, 2026-05-06), GREAT POINT PARTNERS LLC (3.3%, 2026-02-17), Paradigm Biocapital Advisors LP (4.5%, 2026-02-17)

Insider purchases and sales in Q1 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
101Q2 24: 0 buyingQ2 24: 1 sellingQ3 24: 0 buyingQ3 24: 0 sellingQ3 24Q4 24: 0 buyingQ4 24: 1 sellingQ1 25: 0 buyingQ1 25: 1 sellingQ1 25Q2 25: 0 buyingQ2 25: 0 sellingQ3 25: 0 buyingQ3 25: 0 sellingQ3 25Q4 25: 0 buyingQ4 25: 1 sellingQ1 26: 0 buyingQ1 26: 0 sellingQ1 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q2 20240—1$20.4k$20.4k
Q3 20240—0——
Q4 20240—1$12.9k$12.9k
Q1 20250—1$6.7k$6.7k
Q2 20250—0——
Q3 20250—0——
Q4 20250—1$33.7m—
Q1 20260—0——

None reported in Q1 2026.

Holders, Q1 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 TCG Crossover Management, LLC 2.76% of their portfolio PALO ALTO, CA 5,673,0785.7m $96.5m $96.5m 2.76% New
2 RA CAPITAL MANAGEMENT, L.P. 1.02% of their portfolio BOSTON, MA 5,404,9985.4m $96.4m $96.4m 1.02% Unchanged
3 FCPM III SERVICES B.V. 10.17% of their portfolio NAARDEN, P7 4,117,3544.1m $73.5m $73.5m 10.17% Added +500.0k +500,000
4 Venrock Adviser, LLC 2.03% of their portfolio NEW YORK, NY 3,041,7193.0m $54.3m $54.3m 2.03% Added +1.1m +1,097,953
5 Frazier Life Sciences Management, L.P. 1.17% of their portfolio PALO ALTO, CA 2,543,9392.5m $45.4m $45.4m 1.17% Unchanged
6 Caligan Partners LP 2.43% of their portfolio NEW YORK, NY 1,925,0661.9m $34.3m $34.3m 2.43% Added +1,000.0k +999,999
7 GREAT POINT PARTNERS LLC 7.65% of their portfolio Greenwich, CT 1,750,0001.8m $31.2m $31.2m 7.65% Added +379.9k +379,893
8 Paradigm Biocapital Advisors LP 0.64% of their portfolio NEW YORK, NY 1,750,0001.8m $31.2m $31.2m 0.64% Unchanged
9 FMR LLC 0.00% of their portfolio BOSTON, MA 1,539,6701.5m $27.5m $27.5m 0.00% Reduced -986.5k -986,500
10 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 1,433,2801.4m $25.6m $25.6m 0.00% First filing
11 MARSHALL WACE, LLP 0.02% of their portfolio LONDON, X0 1,153,2761.2m $20.6m $20.6m 0.02% New
12 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,118,4581.1m $20.0m $20.0m 0.00% Added +1.0m +1,027,405
13 NEXTBio Capital Management LP 8.28% of their portfolio AUSTIN, TX 999,9671,000.0k $17.8m $17.8m 8.28% Unchanged
14 BlackRock, Inc. 0.00% of their portfolio New York, NY 794,759794.8k $14.2m $14.2m 0.00% Added +329.1k +329,123
15 Logos Global Management LP 0.69% of their portfolio San Francisco, CA 750,000750.0k $13.4m $13.4m 0.69% Added +650.0k +650,000
16 Rosalind Advisors, Inc. 5.12% of their portfolio TORONTO, A6 700,000700.0k $12.5m $12.5m 5.12% New
17 BOOTHBAY FUND MANAGEMENT, LLC 0.23% of their portfolio NEW YORK, NY 555,702555.7k $9.9m $9.9m 0.23% New
18 UBS Group AG 0.00% of their portfolio ZURICH, V8 488,368488.4k $8.7m $8.7m 0.00% Added +196.2k +196,250
19 BRAIDWELL LP 0.28% of their portfolio STAMFORD, CT 466,774466.8k $8.3m $8.3m 0.28% New
20 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 342,573342.6k $6.1m $6.1m 0.00% Added +156.8k +156,765
21 Clearline Capital LP 0.45% of their portfolio NEW YORK, NY 326,168326.2k $5.8m $5.8m 0.45% New
22 SPHERA FUNDS MANAGEMENT LTD. 0.99% of their portfolio TEL AVIV, L3 321,917321.9k $5.7m $5.7m 0.99% Reduced -88.5k -88,500
23 Laurion Capital Management LP 0.53% of their portfolio NEW YORK, NY 318,670318.7k $5.7m $5.7m 0.53% Added +1.4k +1,427
24 Propel Bio Management, LLC 3.52% of their portfolio Los Angeles, CA 314,543314.5k $5.6m $5.6m 3.52% New
25 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 261,891261.9k $4.7m $4.7m 0.00% Added +116.3k +116,251
26 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 258,587258.6k $4.6m $4.6m 0.00% Added +34.1k +34,053
27 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio BALA CYNWYD, PA 232,608232.6k $4.1m $4.1m 0.01% Added +217.8k +217,789
28 VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio MALVERN, PA 185,511185.5k $3.3m $3.3m 0.00% First filing
29 Jump Financial, LLC 0.05% of their portfolio Chicago, IL 173,028173.0k $3.1m $3.1m 0.05% New
30 TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio STAMFORD, CT 152,571152.6k $2.7m $2.7m 0.01% Reduced -15.1k -15,102
31 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 148,768148.8k $2.7m $2.7m 0.00% Reduced -285.1k -285,126
32 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 128,839128.8k $2.3m $2.3m 0.00% New
33 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 116,721116.7k $2.1m $2.1m 0.00% Added +88.3k +88,258
34 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 112,892112.9k $2.0m $2.0m 0.00% Added +112.5k +112,496
35 AXIOM INVESTORS LLC /DE 0.02% of their portfolio GREENWICH, CT 95,74595.7k $1.7m $1.7m 0.02% New
36 Quadrature Capital Ltd 0.02% of their portfolio LONDON, X0 76,63076.6k $1.4m $1.4m 0.02% Added +49.8k +49,839
37 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 75,89075.9k $1.4m $1.4m 0.00% Reduced -15.9k -15,920
38 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 64,54964.5k $1.2m $1.2m 0.00% Added +25.6k +25,603
39 JOHNSON & JOHNSON 0.15% of their portfolio NEW BRUNSWICK, NJ 53,73253.7k $958.6k $958.6k 0.15% Unchanged
40 Simplify Asset Management Inc. 0.01% of their portfolio Las Vegas, NV 53,51053.5k $954.6k $954.6k 0.01% New
41 Rafferty Asset Management, LLC 0.00% of their portfolio New York, NY 50,50550.5k $901.0k $901.0k 0.00% New
42 Brevan Howard Capital Management LP 0.01% of their portfolio ST. HELIER, Y9 42,21742.2k $753.2k $753.2k 0.01% New
43 Irenic Capital Management LP 0.05% of their portfolio NEW YORK, NY 32,66332.7k $582.7k $582.7k 0.05% New
44 Engineers Gate Manager LP 0.01% of their portfolio NEW YORK, NY 26,88026.9k $479.5k $479.5k 0.01% Reduced -1.3k -1,324
45 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 25,48225.5k $454.6k $454.6k 0.00% Added +7.0k +7,023
46 Sarissa Capital Management LP 0.29% of their portfolio GREENWICH, CT 25,39925.4k $453.1k $453.1k 0.29% Unchanged
47 Bollard Group LLC 0.01% of their portfolio BOSTON, MA 23,98724.0k $428.0k $428.0k 0.01% Unchanged
48 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 22,21622.2k $396.3k $396.3k 0.00% New
49 PROFUND ADVISORS LLC 0.01% of their portfolio BETHESDA, MD 22,01522.0k $392.7k $392.7k 0.01% New
50 Scientech Research LLC 0.22% of their portfolio JERSEY CITY, NJ 15,04715.0k $268.4k $268.4k 0.22% New
51 AXQ CAPITAL, LP 0.03% of their portfolio JERSEY CITY, NJ 15,01915.0k $267.9k $267.9k 0.03% New
52 INDEPENDENT FINANCIAL GROUP, LLC 0.01% of their portfolio SAN DIEGO, CA 13,97514.0k $249.3k $249.3k 0.01% Reduced -3.0k -3,025
53 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 13,71613.7k $244.5k $244.5k 0.00% New
54 Vanguard Global Advisers, LLC 0.00% of their portfolio MALVERN, PA 12,87512.9k $229.7k $229.7k 0.00% First filing
55 WINTON GROUP Ltd 0.01% of their portfolio LONDON, X0 11,87011.9k $211.8k $211.8k 0.01% New
56 Cannon Global Investment Management, LLC 0.51% of their portfolio DAVIE, FL 11,70011.7k $208.7k $208.7k 0.51% New
57 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 11,60011.6k $206.9k $206.9k 0.00% New
58 Diametric Capital, LP 0.05% of their portfolio BOSTON, MA 10,07010.1k $179.6k $179.6k 0.05% New
59 GROUP ONE TRADING LLC 0.01% of their portfolio CHICAGO, IL 9,0659.1k $161.7k $161.7k 0.01% New
60 China Universal Asset Management Co., Ltd. 0.01% of their portfolio SHANGHAI, F4 7,3687.4k $131.4k $131.4k 0.01% Added +4.6k +4,622
61 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 5,3735.4k $95.9k $95.9k 0.00% Reduced -967 -967
62 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 4,3644.4k $64.2k $64.2k 0.00% Added +2.1k +2,052
63 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 3,5133.5k $51.6k $51.6k 0.00% New
64 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 3,4663.5k $61.8k $61.8k 0.00% Added +1.7k +1,737
65 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 2,8442.8k $50.7k $50.7k 0.00% Added +2.6k +2,553
66 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 2,1662.2k $38.6k $38.6k 0.00% Added +1.3k +1,347
67 GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio GUANGZHOU, F4 372372 $6.6k $6.6k 0.00% Added +42 +42
68 Quantbot Technologies LP 0.00% of their portfolio NEW YORK, NY 307307 $5.5k $5.5k 0.00% New
69 PNC Financial Services Group, Inc. 0.00% of their portfolio Pittsburgh, PA 246246 $4.4k $4.4k 0.00% New
70 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 199199 $4.0k $4.0k 0.00% Added +192 +192
71 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 136136 $2.4k $2.4k 0.00% Reduced -1.3k -1,263
72 Allworth Financial LP 0.00% of their portfolio FOLSOM, CA 7373 $1.3k $1.3k 0.00% Added +70 +70
73 Parallel Advisors, LLC 0.00% of their portfolio SAN FRANCISCO, CA 4848 $856 $856 0.00% New
74 MAI Capital Management 0.00% of their portfolio INDEPENDENCE, OH 4040 $714 $714 0.00% Unchanged
75 SIGNATUREFD, LLC 0.00% of their portfolio ATLANTA, GA 3939 $696 $696 0.00% New
76 Ameritas Advisory Services, LLC 0.00% of their portfolio Lincoln, NE 3737 $660 $660 0.00% New
77 Fortitude Family Office, LLC 0.00% of their portfolio SCOTTSDALE, AZ 3131 $553 $553 0.00% New
78 WPG Advisers, LLC 0.00% of their portfolio BALTIMORE, MD 2121 $375 $375 0.00% New
79 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 33 $54 $54 0.00% Unchanged
80 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 11 $18 $18 0.00% Unchanged