Vault-13

VOR BIOPHARMA INC

COM · CUSIP 929033108

35 institutional holders -11 vs Q1 2025
57,027,35957.0m shares reported held*
$91.8mreported value*
8 new 8 added 10 reduced 19 sold out net sold ≈ $5.0m (-3.1m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $1.61. Options: 6 managers hold calls ($9.8m notional), 7 hold puts ($610.9k).

Trends to Q2 2025

Institutional holders

Managers reporting a position, each quarter

0255075Q3 22: 49Q4 22: 59Q1 23: 61Q2 23: 72Q3 23: 60Q4 23: 61Q1 24: 70Q2 24: 72Q3 24: 55Q4 24: 53Q1 25: 46Q2 25: 3535Q3 22Q2 23Q1 24Q4 24Q2 25
Numbers
QuarterHolders
Q3 202249
Q4 202259
Q1 202361
Q2 202372
Q3 202360
Q4 202361
Q1 202470
Q2 202472
Q3 202455
Q4 202453
Q1 202546
Q2 202535

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
50050Q3 23: 19 bought or addedQ3 23: 31 cut or sold outQ4 23: 28 bought or addedQ4 23: 18 cut or sold outQ4 23Q1 24: 32 bought or addedQ1 24: 21 cut or sold outQ2 24: 39 bought or addedQ2 24: 41 cut or sold outQ2 24Q3 24: 17 bought or addedQ3 24: 45 cut or sold outQ4 24: 19 bought or addedQ4 24: 31 cut or sold outQ4 24Q1 25: 18 bought or addedQ1 25: 33 cut or sold outQ2 25: 16 bought or addedQ2 25: 29 cut or sold outQ2 25
Numbers
QuarterBought or addedCut or sold out
Q3 20231931
Q4 20232818
Q1 20243221
Q2 20243941
Q3 20241745
Q4 20241931
Q1 20251833
Q2 20251629

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$2.5m$5m$7.5m$10mQ3 24 calls: $13.4kQ3 24 puts: $70Q3 24P/C 0.01Q4 24 calls: $78.0kQ4 24 puts: $12.7kQ4 24P/C 0.16Q1 25 calls: $28.0kQ1 25 puts: $7.0kQ1 25P/C 0.25Q2 25 calls: $9.8mQ2 25 puts: $610.9kQ2 25P/C 0.06
Numbers
QuarterCallsPutsP/C
Q3 2024$13.4k$700.01
Q4 2024$78.0k$12.7k0.16
Q1 2025$28.0k$7.0k0.25
Q2 2025$9.8m$610.9k0.06

Biggest buyers

UBS Group AG Added +1,523,181+1.5m
HRT FINANCIAL LP New +474,575+474.6k
Scientech Research LLC New +403,859+403.9k
JANE STREET GROUP, LLC Added +330,857+330.9k
Virtu Financial LLC New +275,912+275.9k
GOLDMAN SACHS GROUP INC Added +95,843+95.8k
TWO SIGMA SECURITIES, LLC New +94,394+94.4k
CITIGROUP INC New +87,485+87.5k
TWO SIGMA INVESTMENTS, LP Added +46,645+46.6k
XTX Topco Ltd New +40,943+40.9k

Biggest sellers

FMR LLC Reduced -4,329,810-4.3m
SUSQUEHANNA INTERNATIONAL GROUP, LLP Sold out -384,293-384.3k
MAI Capital Management Reduced -284,711-284.7k
RENAISSANCE TECHNOLOGIES LLC Reduced -233,319-233.3k
MILLENNIUM MANAGEMENT LLC Sold out -186,849-186.8k
EXCHANGE TRADED CONCEPTS, LLC Sold out -148,073-148.1k
OMERS ADMINISTRATION Corp Sold out -139,600-139.6k
BRIDGEWAY CAPITAL MANAGEMENT, LLC Sold out -120,900-120.9k
BlackRock, Inc. Reduced -109,743-109.7k
BARCLAYS PLC Sold out -99,739-99.7k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP New $4.5m2.8m shares
GROUP ONE TRADING LLC Added $2.3m1.4m shares
CITADEL ADVISORS LLC New $1.2m756.9k shares
JANE STREET GROUP, LLC New $956.1k590.2k shares
SIMPLEX TRADING, LLC New $806.0k498.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

MILLENNIUM MANAGEMENT LLC New $178.2k110.0k shares
Eisler Capital Management Ltd. New $162.3k100.5k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP New $96.4k59.5k shares
LMR Partners LLP New $81.0k50.0k shares
JANE STREET GROUP, LLC New $71.0k43.8k shares
SIMPLEX TRADING, LLC Added $22.0k13.6k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence -0.1 pts · filed 2025-06-27 31.8% -0.1 pts 39.7m 2025-06-27
Reprogrammed Interchange LLC 13D · may seek influence -1.5 pts · filed 2025-10-16
Stated purposeItem 4 of Schedule 13D is hereby amended and supplemented as follows: From October 10, 2025 through October 14, 2025, Reprogrammed Interchange LLC sold the following shares of Vor Biopharma Inc. in open market transactions, resulting in a decrease in the number of shares of Common Stock beneficially owned by the Reporting Persons by more than one percent of the outstanding shares of Common Stock of the Issuer. 1. 40,983 shares on October 10, 2025, at a weighted average per share sale price of $30.9673. 2. 22,006 shares on October 13, 2025, at a weighted average per share sale price of $32.436. 3. 33,668 shares on October 14, 2025, at a weighted average per share sale price of $30.3192. Full filing
 18.6% -1.5 pts 1.3m 2025-10-16

Holders, Q2 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 RA CAPITAL MANAGEMENT, L.P. 1.08% of their portfolio BOSTON, MA 39,646,03939.6m $64.2m $64.2m 1.08% Unchanged
2 5AM Venture Management, LLC 3.96% of their portfolio SAN FRANCISCO, CA 6,361,7236.4m $10.3m $10.3m 3.96% Unchanged
3 FMR LLC 0.00% of their portfolio BOSTON, MA 2,092,6862.1m $3.4m $3.4m 0.00% Reduced -4.3m -4,329,810
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,915,6061.9m $3.1m $3.1m 0.00% Reduced -24.6k -24,617
5 UBS Group AG 0.00% of their portfolio ZURICH, V8 1,531,6361.5m $2.5m $2.5m 0.00% Added +1.5m +1,523,181
6 JOHNSON & JOHNSON 0.34% of their portfolio NEW BRUNSWICK, NJ 1,074,6581.1m $1.1m $1.1m 0.34% Unchanged
7 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 525,613525.6k $851.5k $851.5k 0.00% Added +330.9k +330,857
8 Sarissa Capital Management LP 0.53% of their portfolio GREENWICH, CT 508,016508.0k $823.0k $823.0k 0.53% Unchanged
9 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 474,575474.6k $768.0k $768.0k 0.00% New
10 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 468,112468.1k $758.3k $758.3k 0.00% Reduced -233.3k -233,319
11 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 435,560435.6k $705.8k $705.8k 0.00% Reduced -2.5k -2,450
12 Scientech Research LLC 0.16% of their portfolio JERSEY CITY, NJ 403,859403.9k $654.3k $654.3k 0.16% New
13 BlackRock, Inc. 0.00% of their portfolio New York, NY 374,763374.8k $607.1k $607.1k 0.00% Reduced -109.7k -109,743
14 Virtu Financial LLC 0.02% of their portfolio New York, NY 275,912275.9k $447.0k $447.0k 0.02% New
15 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 180,788180.8k $292.9k $292.9k 0.00% Added +95.8k +95,843
16 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 169,636169.6k $274.8k $274.8k 0.00% Added +46.6k +46,645
17 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 115,934115.9k $187.8k $187.8k 0.00% Unchanged
18 TWO SIGMA SECURITIES, LLC 0.02% of their portfolio NEW YORK, NY 94,39494.4k $152.9k $152.9k 0.02% New
19 Trustees of Columbia University in the City of New York 0.02% of their portfolio NEW YORK, NY 91,91091.9k $148.9k $148.9k 0.02% Unchanged
20 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 87,48587.5k $141.7k $141.7k 0.00% New
21 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 72,41772.4k $117.3k $117.3k 0.00% Reduced -74.6k -74,605
22 Bollard Group LLC 0.00% of their portfolio BOSTON, MA 55,55555.6k $90.0k $90.0k 0.00% Unchanged
23 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 40,94340.9k $66.3k $66.3k 0.00% New
24 Chicago Partners Investment Group LLC 0.00% of their portfolio CHICAGO, IL 10,88710.9k $22.8k $22.8k 0.00% Reduced -1.8k -1,844
25 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 8,9979.0k $14.6k $14.6k 0.00% Added +7.1k +7,138
26 MAI Capital Management 0.00% of their portfolio INDEPENDENCE, OH 3,6523.7k $5.9k $5.9k 0.00% Reduced -284.7k -284,711
27 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 2,2952.3k $3.7k $3.7k 0.00% Reduced -1.2k -1,153
28 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 1,0171.0k $1.6k $1.6k 0.00% Unchanged
29 LANARK FINANCIAL, INC. 0.00% of their portfolio BIRMINGHAM, AL 1,0001.0k $1.0k $1.0k 0.00% New
30 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 610610 $989 $989 0.00% Added +50 +50
31 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 503503 $815 $815 0.00% Reduced -34.9k -34,938
32 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 400400 $648 $648 0.00% Added +267 +267
33 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 118118 $0 $0 0.00% Added +63 +63
34 Allworth Financial LP 0.00% of their portfolio FOLSOM, CA 6060 $98 $98 0.00% New
35 CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio BIRMINGHAM, AL 00 $0 $0 — Unchanged