VIR BIOTECHNOLOGY INC VIR
COM · Common Stock · CUSIP 92764N102 · ISIN US92764N1028
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($46.5k this quarter). Holder counts are more reliable. Shares outstanding: 139.1m as of 2025-10-29, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.03. Options: 9 managers hold calls ($1.7m notional), 4 hold puts ($340.1k).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 221 |
| Q4 2022 | 225 |
| Q1 2023 | 234 |
| Q2 2023 | 228 |
| Q3 2023 | 215 |
| Q4 2023 | 206 |
| Q1 2024 | 212 |
| Q2 2024 | 216 |
| Q3 2024 | 198 |
| Q4 2024 | 209 |
| Q1 2025 | 235 |
| Q2 2025 | 214 |
| Q3 2025 | 213 |
| Q4 2025 | 218 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 101 | 94 |
| Q2 2024 | 106 | 99 |
| Q3 2024 | 95 | 103 |
| Q4 2024 | 100 | 99 |
| Q1 2025 | 120 | 96 |
| Q2 2025 | 104 | 102 |
| Q3 2025 | 88 | 108 |
| Q4 2025 | 92 | 105 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $1.9m | $1.8m | 0.97 |
| Q2 2025 | $2.3m | $960.6k | 0.43 |
| Q3 2025 | $1.4m | $742.3k | 0.51 |
| Q4 2025 | $1.7m | $340.1k | 0.20 |
Biggest buyers
| Balyasny Asset Management L.P. | New | +1.4m |
| Candriam S.C.A. | New | +1.0m |
| STATE STREET CORP | Added | +988.3k |
| Boxer Capital Management, LLC | New | +625.0k |
| AMERIPRISE FINANCIAL INC | Added | +537.0k |
| BANK OF AMERICA CORP /DE/ | Added | +529.9k |
| HRT FINANCIAL LP | Added | +414.9k |
| Hudson Bay Capital Management LP | Added | +413.1k |
| BlackRock, Inc. | Added | +362.4k |
| Nuveen, LLC | Added | +360.1k |
Biggest sellers
| SB INVESTMENT ADVISERS (UK) LTD | Reduced | -3.6m |
| ROYAL BANK OF CANADA | Reduced | -711.6k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -552.6k |
| JPMORGAN CHASE & CO | Reduced | -480.4k |
| FMR LLC | Reduced | -478.7k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -442.6k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -393.9k |
| CITADEL ADVISORS LLC | Reduced | -309.8k |
| Squarepoint Ops LLC | Reduced | -256.4k |
| VANGUARD GROUP INC | Reduced | -250.4k |
Biggest calls
| DIADEMA PARTNERS LP | New | $537.9k89.2k shares |
| SIMPLEX TRADING, LLC | Added | $397.4k65.9k shares |
| CITADEL ADVISORS LLC | Added | $246.0k40.8k shares |
| DLD Asset Management, LP | New | $180.6k30.0k shares |
| Walleye Capital LLC | Reduced | $148.9k24.7k shares |
| NOMURA HOLDINGS INC | Reduced | $84.4k14.0k shares |
| JANE STREET GROUP, LLC | New | $77.2k12.8k shares |
| Persistent Asset Partners Ltd | New | $20.9k238 shares |
| GROUP ONE TRADING LLC | Added | $19.9k3.3k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $244.2k40.5k shares |
| CITADEL ADVISORS LLC | Reduced | $83.8k13.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $7.8k1.3k shares |
| GROUP ONE TRADING LLC | Unchanged | $4.2k700 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +1.6 pts · filed 2026-10-27 | 12.4% |
| ARCH Venture Fund IX, L.P. 13D · may seek influence filed 2026-03-03 | 8.5% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.1 pts · filed 2026-07-31 | 6.8% |
| SB INVESTMENT ADVISERS (UK) LTD 13G · exempt (held before listing) -2.9 pts · filed 2026-05-15 | 6.5% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.9% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 4 | $954.5k | $895.1k |
| Q2 2024 | 0 | — | 3 | $761.6k | $717.8k |
| Q3 2024 | 0 | — | 1 | $95.1k | $95.1k |
| Q4 2024 | 0 | — | 1 | $77.4k | $76.8k |
| Q1 2025 | 0 | — | 6 | $771.1k | $771.1k |
| Q2 2025 | 0 | — | 2 | $490.4k | $490.4k |
| Q3 2025 | 0 | — | 2 | $388.5k | $388.5k |
| Q4 2025 | 0 | — | 3 | $442.7k | $442.7k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-12-01 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $1.1m191.9k shares |
| 2025-12-01 | SATO VICKI L Director | Sold plan | $132.0k22.0k shares |
| 2025-11-28 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $396.0k61.5k shares |
| 2025-11-26 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $817.5k127.9k shares |
| 2025-11-25 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $1.5m236.0k shares |
| 2025-11-24 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $1.4m227.8k shares |
| 2025-11-17 | O'Byrne Jason EVP & Chief Financial Officer | Sold plan | $37.8k6.8k shares |
| 2025-11-05 | de Verneuil Vanina EVP, General Counsel, Corp Sec | Sold plan | $12.3k2.4k shares |
| 2025-11-03 | SATO VICKI L Director | Sold plan | $124.1k22.0k shares |
| 2025-11-03 | de Verneuil Vanina EVP and General Counsel | Sold plan | $8.0k1.4k shares |
| 2025-10-29 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $649100 shares |
| 2025-10-28 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $158.9k24.5k shares |
| 2025-10-27 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $401.7k66.4k shares |
| 2025-10-24 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $278.3k46.7k shares |
| 2025-10-23 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $924.8k154.4k shares |
| 2025-10-22 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $887.2k144.3k shares |
| 2025-10-21 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $691.0k109.7k shares |
| 2025-10-20 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $1.4m220.5k shares |
| 2025-10-16 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $78.3k12.8k shares |
| 2025-10-15 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $101.2k16.7k shares |
| 2025-10-10 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $14.0k2.3k shares |
| 2025-10-09 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $1.5m249.1k shares |
| 2025-10-08 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $2.8m466.2k shares |
| 2025-10-07 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $403.9k72.1k shares |
| 2025-10-06 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $420.8k74.0k shares |
| 2025-10-03 | SB INVESTMENT ADVISERS (UK) LTD +2 10% owner · See footnote | Sold plan | $2.5m450.3k shares |
| 2025-10-01 | SATO VICKI L Director | Sold plan | $128.5k22.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 16.3m $98.5m | Added +362.4k |
| SB INVESTMENT ADVISERS (UK) LTD 0.79% of their portfolio | 13.1m $79.1m | Reduced -3.6m |
| ARCH Venture Management, LLC 11.95% of their portfolio | 12.9m $77.9m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 12.5m $75.7m | Reduced -250.4k |
| GSK plc 6.45% of their portfolio | 8.6m $51.6m | First filing |
| STATE STREET CORP 0.00% of their portfolio | 6.2m $37.6m | Added +988.3k |
| FMR LLC 0.00% of their portfolio | 3.2m $19.0m | Reduced -478.7k |
| MORGAN STANLEY 0.00% of their portfolio | 2.7m $16.2m | Reduced -10.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 2.5m $15.3m | Reduced -442.6k |
| ORBIMED ADVISORS LLC 0.29% of their portfolio | 2.4m $14.4m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.3m $14.0m | Added +82.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.6m $9.5m | Added +47.1k |
| Aberdeen Group plc 0.01% of their portfolio | 1.4m $8.4m | Reduced -135.7k |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 1.4m $8.3m | New |
| Hudson Bay Capital Management LP 0.05% of their portfolio | 1.3m $8.0m | Added +413.1k |
| Candriam S.C.A. 0.03% of their portfolio | 1.0m $6.2m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 1.0m $6.0m | Reduced -393.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 930.9k $5.6m | Added +529.9k |
| GordonMD Global Investments LP 4.02% of their portfolio | 930.3k $5.6m | First filing |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 904.5k $5.5m | Reduced -238.4k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 848.5k $5.1m | Reduced -58.7k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 731.3k $4.4m | Added +537.0k |
| Boxer Capital Management, LLC 0.82% of their portfolio | 625.0k $3.8m | New |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 614.5k $3.7m | Reduced -552.6k |
| NORDEA INVESTMENT MANAGEMENT AB 0.00% of their portfolio | 609.7k $3.5m | Reduced -104.8k |
| Clarius Group, LLC 0.21% of their portfolio | 608.2k $3.7m | Reduced -11.1k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 598.7k $3.5m | Added +142.4k |
| HRT FINANCIAL LP 0.01% of their portfolio | 591.6k $3.6m | Added +414.9k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 589.6k $3.6m | Reduced -59.7k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 577.7k $3.5m | Added +73.7k |
| Ikarian Capital, LLC 0.45% of their portfolio | 575.7k $3.5m | Reduced -17.7k |
| Nuveen, LLC 0.00% of their portfolio | 565.5k $3.4m | Added +360.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 545.6k $3.3m | Reduced -11.5k |
| BAKER BROS. ADVISORS LP 0.02% of their portfolio | 542.5k $3.3m | Unchanged |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 531.4k $3.2m | Reduced -23.6k |
| Corient Private Wealth LP 0.00% of their portfolio | 522.9k $3.1m | Added +263.2k |
| Alta Partners Management Company, L.P. 2.97% of their portfolio | 509.9k $3.1m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 489.2k $3.0m | Reduced -309.8k |
| Sio Capital Management, LLC 0.48% of their portfolio | 478.3k $2.9m | Unchanged |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 450.6k $2.7m | Reduced -5.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 418.6k $2.5m | Reduced -480.4k |
| UBS Group AG 0.00% of their portfolio | 418.0k $2.5m | Added +203.2k |
| Invesco Ltd. 0.00% of their portfolio | 405.7k $2.4m | Reduced -12.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 390.1k $2.4m | Added +112.4k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 371.3k $2.2m | Added +10.9k |
| BARCLAYS PLC 0.00% of their portfolio | 365.8k $2.2m | Reduced -44.6k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.01% of their portfolio | 327.4k $2.0m | Reduced -189.2k |
| Public Sector Pension Investment Board 0.01% of their portfolio | 326.2k $2.0m | Reduced -41.1k |
| CITIGROUP INC 0.00% of their portfolio | 311.3k $1.9m | Reduced -12.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 295.4k $1.8m | Reduced -626 |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 281.5k $1.7m | Added +29.2k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 279.7k $1.7m | Added +260.5k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 264.0k $1.6m | Added +191.8k |
| Walleye Capital LLC 0.01% of their portfolio | 256.1k $1.5m | Added +117.3k |
| Legal & General Group Plc 0.00% of their portfolio | 240.6k $1.5m | Reduced -4.3k |
| Eagle Health Investments LP 0.32% of their portfolio | 240.5k $1.5m | Unchanged |
| Tejara Capital Ltd 0.58% of their portfolio | 231.2k $1.4m | Reduced -25.7k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 208.4k $1.3m | Reduced -18.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 206.2k $1.2m | Added +3.1k |
| Allianz Asset Management GmbH 0.00% of their portfolio | 205.1k $1.2m | Reduced -79.1k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 195.7k $1.2m | New |
| WINTON GROUP Ltd 0.04% of their portfolio | 189.3k $1.1m | Added +131.6k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 186.3k $1.1m | Added +34.2k |
| Swiss National Bank 0.00% of their portfolio | 178.0k $1.1m | Added +7.8k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 177.1k $1.1m | Added +17.2k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.02% of their portfolio | 135.7k $818.3k | Reduced -22.4k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 133.8k $806.6k | Added +19.0k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 126.1k $760.0k | Added +43.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 121.1k $730.1k | Reduced -22.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 109.6k $661.0k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 107.0k $643.6k | Added +1.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 105.4k $635.6k | Added +30.0k |
| DIADEMA PARTNERS LP 0.36% of their portfolio | 100.0k $603.0k | New |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 97.9k $588.0k | Added +3.1k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 87.8k $529.3k | Reduced -20.5k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 83.1k $500.8k | Reduced -189.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 81.6k $493.0k | Added +34.5k |
| Creative Planning 0.00% of their portfolio | 79.7k $480.6k | Added +27.0k |
| Jain Global LLC 0.00% of their portfolio | 73.0k $440.1k | Added +54.6k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 68.6k $413.5k | New |
| LMR Partners LLP 0.00% of their portfolio | 67.8k $408.8k | Reduced -100.0k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 65.7k $396.4k | Unchanged |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 65.0k $392.0k | Reduced -3.1k |
| Persistent Asset Partners Ltd 0.18% of their portfolio | 63.5k $383.2k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 61.8k $363.5k | Added +4.2k |
| XTX Topco Ltd 0.01% of their portfolio | 60.1k $362.3k | Reduced -79.8k |
| Campbell & CO Investment Adviser LLC 0.02% of their portfolio | 59.8k $360.5k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 59.4k $358.0k | Reduced -9.6k |
| Rathbones Group PLC 0.00% of their portfolio | 57.2k $345.0k | Added +28.6k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 56.7k $341.9k | Added +29.0k |
| Quinn Opportunity Partners LLC 0.01% of their portfolio | 51.0k $307.4k | Unchanged |
| Quadrature Capital Ltd 0.00% of their portfolio | 49.8k $300.3k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 49.8k $300.2k | Added +16.3k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 49.6k $299.2k | New |
| Susquehanna Portfolio Strategies, LLC 0.00% of their portfolio | 47.4k $286.0k | Unchanged |
| State of Alaska, Department of Revenue 0.00% of their portfolio | 47.3k $285.0k | Reduced -208 |
| MARTINGALE ASSET MANAGEMENT L P 0.01% of their portfolio | 44.8k $270.2k | Reduced -2.2k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 43.7k $259.8k | Reduced -6.3k |
| Louisiana State Employees Retirement System 0.00% of their portfolio | 43.3k $261.1k | Reduced -100 |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 40.1k $241.9k | Reduced -406 |