VAXCYTE INC PCVX
COM · Common Stock · CUSIP 92243G108 · ISIN US92243G1085
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Carlos, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($3.0m this quarter). Holder counts are more reliable. Shares outstanding: 95.2m as of 2023-11-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $62.79. Options: 9 managers hold calls ($9.9m notional), 6 hold puts ($2.9m).
Trends to Q4 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 126 |
| Q4 2022 | 199 |
| Q1 2023 | 190 |
| Q2 2023 | 199 |
| Q3 2023 | 204 |
| Q4 2023 | 225 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 167 | 33 |
| Q1 2023 | 94 | 92 |
| Q2 2023 | 140 | 66 |
| Q3 2023 | 108 | 74 |
| Q4 2023 | 112 | 84 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2023 | $6.9m | $3.5m | 0.50 |
| Q2 2023 | $6.1m | $24.7m | 4.05 |
| Q3 2023 | $2.8m | $2.2m | 0.78 |
| Q4 2023 | $9.9m | $2.9m | 0.30 |
Biggest buyers
| BlackRock Inc. | Added | +1.2m |
| LORD, ABBETT & CO. LLC | New | +771.1k |
| MORGAN STANLEY | Added | +665.2k |
| Darwin Global Management, Ltd. | New | +580.0k |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Added | +451.7k |
| Driehaus Capital Management LLC | Added | +350.5k |
| SAMLYN CAPITAL, LLC | New | +329.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +260.2k |
| STATE STREET CORP | Added | +244.3k |
| EVENTIDE ASSET MANAGEMENT, LLC | Added | +214.2k |
Biggest sellers
| Medicxi Ventures Management (Jersey) Ltd | Sold out | -1.0m |
| Point72 Asset Management, L.P. | Reduced | -621.0k |
| FRED ALGER MANAGEMENT, LLC | Reduced | -423.1k |
| Nicholas Investment Partners, LP | Reduced | -349.3k |
| BRAIDWELL LP | Reduced | -329.6k |
| Pictet Asset Management Holding SA | Reduced | -325.6k |
| Kynam Capital Management, LP | Reduced | -300.0k |
| JENNISON ASSOCIATES LLC | Reduced | -278.5k |
| PERCEPTIVE ADVISORS LLC | Reduced | -254.3k |
| Avidity Partners Management LP | Reduced | -186.0k |
Biggest calls
| NOMURA HOLDINGS INC | New | $4.1m65.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.4m53.8k shares |
| GROUP ONE TRADING LLC | Added | $923.2k14.7k shares |
| JANE STREET GROUP, LLC | New | $665.7k10.6k shares |
| CITADEL ADVISORS LLC | Added | $427.0k6.8k shares |
| SIMPLEX TRADING, LLC | Added | $295.0k4.7k shares |
| Cutler Group LLC / CA | New | $78.0k5.0k shares |
| Walleye Capital LLC | New | $50.2k800 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.8m44.5k shares |
| CITADEL ADVISORS LLC | Unchanged | $138.2k2.2k shares |
| GROUP ONE TRADING LLC | Reduced | $6.3k100 shares |
| SIMPLEX TRADING, LLC | Reduced | $6.0k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| Cutler Group LLC / CA | New | $05.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +3.0 pts · filed 2026-08-06 | 14.4% |
| Janus Henderson Group Ltd. 13G · institution +12.0 pts · filed 2026-08-11 | 12.1% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor -1.0 pts · filed 2026-05-15 | 8.9% |
| T. Rowe Price Investment Management, Inc. 13G · institution +2.2 pts · filed 2026-02-17 | 8.6% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 7.6% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q4 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2022 | 0 | — | 5 | $1.5m | — |
| Q2 2022 | 0 | — | 5 | $1.6m | — |
| Q3 2022 | 0 | — | 5 | $3.9m | — |
| Q4 2022 | 0 | — | 3 | $1.1m | — |
| Q1 2023 | 0 | — | 1 | $14.5k | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 2 | $1.1m | $1.1m |
| Q4 2023 | 0 | — | 4 | $6.9m | $6.9m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-12-26 | PICKERING GRANT Chief Executive Officer, director | Sold plan | $925.5k15.0k shares |
| 2023-12-18 | GUGGENHIME ANDREW President and CFO | Sold plan | $481.4k8.0k shares |
| 2023-12-14 | GUGGENHIME ANDREW President and CFO | Sold plan | $843.1k14.0k shares |
| 2023-12-07 | Eydelman Mikhail SVP, Gen Counsel & Corp Sec | Sold plan | $565.0k10.0k shares |
| 2023-12-01 | Wassil Jim Chief Operating Officer | Sold plan | $156.4k3.0k shares |
| 2023-12-01 | PICKERING GRANT Chief Executive Officer, director · By Children's Trust | Sold plan | $136.4k2.6k shares |
| 2023-11-24 | PICKERING GRANT Chief Executive Officer, director | Sold plan | $736.3k15.0k shares |
| 2023-11-20 | GUGGENHIME ANDREW President and CFO | Sold plan | $409.1k8.0k shares |
| 2023-11-01 | Wassil Jim Chief Operating Officer | Sold plan | $141.8k3.0k shares |
| 2023-11-01 | PICKERING GRANT Chief Executive Officer, director · By Children's Trust | Sold plan | $123.8k2.6k shares |
| 2023-10-23 | PICKERING GRANT Chief Executive Officer, director | Sold plan | $706.1k15.0k shares |
| 2023-10-18 | GUGGENHIME ANDREW President and CFO | Sold plan | $367.3k8.0k shares |
| 2023-10-02 | Eydelman Mikhail SVP, Gen Counsel & Corp Sec | Sold plan | $1.0m20.0k shares |
| 2023-10-02 | Wassil Jim Chief Operating Officer | Sold plan | $151.3k3.0k shares |
| 2023-10-02 | PICKERING GRANT Chief Executive Officer, director · By Children's Trust | Sold plan | $132.0k2.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2023
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.07% of their portfolio | 14.2m $892.6m | Added +136.3k |
| BlackRock Inc. 0.01% of their portfolio | 8.6m $538.6m | Added +1.2m |
| VANGUARD GROUP INC 0.01% of their portfolio | 8.5m $530.8m | Added +168.1k |
| RA CAPITAL MANAGEMENT, L.P. 7.74% of their portfolio | 7.9m $495.6m | Unchanged |
| JANUS HENDERSON GROUP PLC 0.26% of their portfolio | 7.0m $438.4m | Reduced -79.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.05% of their portfolio | 4.4m $278.3m | Reduced -166.8k |
| Capital Research Global Investors 0.05% of their portfolio | 3.4m $216.0m | Added +76.0k |
| STATE STREET CORP 0.01% of their portfolio | 3.4m $212.9m | Added +244.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 2.7m $168.2m | Added +260.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 2.0m $123.9m | Added +98.4k |
| ALLIANCEBERNSTEIN L.P. 0.05% of their portfolio | 1.9m $120.3m | Reduced -28.8k |
| Driehaus Capital Management LLC 1.27% of their portfolio | 1.7m $105.2m | Added +350.5k |
| FRED ALGER MANAGEMENT, LLC 0.57% of their portfolio | 1.7m $104.9m | Reduced -423.1k |
| JENNISON ASSOCIATES LLC 0.07% of their portfolio | 1.5m $92.7m | Reduced -278.5k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.53% of their portfolio | 1.5m $91.4m | Added +451.7k |
| BRAIDWELL LP 2.98% of their portfolio | 1.3m $81.0m | Reduced -329.6k |
| T. Rowe Price Investment Management, Inc. 0.05% of their portfolio | 1.2m $78.3m | Added +41.4k |
| Frazier Life Sciences Management, L.P. 3.91% of their portfolio | 1.2m $73.1m | Unchanged |
| ORBIMED ADVISORS LLC 1.45% of their portfolio | 1.2m $72.4m | Added +145.9k |
| Pictet Asset Management Holding SA 0.08% of their portfolio | 1.1m $72.2m | Reduced -325.6k |
| Commodore Capital LP 6.04% of their portfolio | 1.1m $69.1m | Unchanged |
| PERCEPTIVE ADVISORS LLC 1.53% of their portfolio | 1.1m $68.4m | Reduced -254.3k |
| FRANKLIN RESOURCES INC 0.03% of their portfolio | 1.1m $67.6m | Added +121.0k |
| MORGAN STANLEY 0.00% of their portfolio | 1.1m $67.5m | Added +665.2k |
| Kynam Capital Management, LP 7.12% of their portfolio | 1.0m $63.0m | Reduced -300.0k |
| NORGES BANK 0.01% of their portfolio | 915.5k $57.5m | Added +130.0k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 884.3k $55.5m | Reduced -12.4k |
| NOVO HOLDINGS A/S 3.28% of their portfolio | 845.0k $53.1m | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 810.7k $50.9m | Added +172.9k |
| Pivotal bioVenture Partners Investment Advisor LLC 12.63% of their portfolio | 793.0k $49.8m | Unchanged |
| LORD, ABBETT & CO. LLC 0.09% of their portfolio | 771.1k $48.4m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 730.4k $45.9m | Added +17.6k |
| MILLENNIUM MANAGEMENT LLC 0.04% of their portfolio | 691.4k $43.4m | Added +108.6k |
| Cormorant Asset Management, LP 2.00% of their portfolio | 665.0k $41.8m | Unchanged |
| EVENTIDE ASSET MANAGEMENT, LLC 0.62% of their portfolio | 607.2k $38.1m | Added +214.2k |
| Darwin Global Management, Ltd. 7.15% of their portfolio | 580.0k $36.4m | New |
| Avidity Partners Management LP 1.37% of their portfolio | 570.1k $35.8m | Reduced -186.0k |
| Vestal Point Capital, LP 3.49% of their portfolio | 525.0k $33.0m | First filing |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 481.1k $30.2m | Added +52.0k |
| D. E. Shaw & Co., Inc. 0.04% of their portfolio | 438.3k $27.5m | Reduced -100.1k |
| Soleus Capital Management, L.P. 2.89% of their portfolio | 415.4k $26.1m | Reduced -84.2k |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 407.2k $25.6m | Added +35.5k |
| Bank of New York Mellon Corp 0.01% of their portfolio | 399.1k $25.1m | Added +3.1k |
| FEDERATED HERMES, INC. 0.06% of their portfolio | 394.2k $24.8m | Reduced -1.6k |
| Woodline Partners LP 0.27% of their portfolio | 393.4k $24.7m | Added +12.7k |
| VICTORY CAPITAL MANAGEMENT INC 0.03% of their portfolio | 379.4k $23.8m | Reduced -51.5k |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 361.1k $22.7m | Added +85.3k |
| GREAT POINT PARTNERS LLC 3.85% of their portfolio | 360.0k $22.6m | Reduced -171.2k |
| First Turn Management, LLC 3.22% of their portfolio | 357.5k $22.5m | First filing |
| EAGLE ASSET MANAGEMENT INC 0.12% of their portfolio | 354.1k $22.2m | Reduced -885 |
| Amundi 0.01% of their portfolio | 329.8k $20.0m | Reduced -13.1k |
| SAMLYN CAPITAL, LLC 0.45% of their portfolio | 329.2k $20.7m | New |
| TANG CAPITAL MANAGEMENT LLC 1.74% of their portfolio | 300.0k $18.8m | Unchanged |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 280.9k $17.6m | Reduced -15.6k |
| Parkman Healthcare Partners LLC 2.38% of their portfolio | 267.6k $16.8m | Added +29.5k |
| Eversept Partners, LP 1.44% of their portfolio | 233.8k $14.7m | Added +43.4k |
| PUTNAM INVESTMENTS LLC 0.02% of their portfolio | 227.1k $14.3m | Added +120.7k |
| Invesco Ltd. 0.00% of their portfolio | 227.0k $14.3m | Added +75.4k |
| Polar Asset Management Partners Inc. 0.36% of their portfolio | 214.3k $13.5m | Reduced -111.3k |
| BARCLAYS PLC 0.01% of their portfolio | 201.7k $12.7m | Added +31.3k |
| Pier Capital, LLC 1.81% of their portfolio | 201.6k $12.7m | Reduced -2.2k |
| Aberdeen Group plc 0.03% of their portfolio | 194.2k $12.2m | New |
| COMERICA BANK 0.05% of their portfolio | 187.8k $11.8m | Added +101.4k |
| VOYA INVESTMENT MANAGEMENT LLC 0.01% of their portfolio | 183.9k $11.5m | Added +1.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 174.2k $10.9m | Reduced -36.0k |
| TD Asset Management Inc 0.01% of their portfolio | 167.0k $10.5m | Added +15.9k |
| UBS Group AG 0.00% of their portfolio | 166.0k $10.4m | Added +91.7k |
| SEGALL BRYANT & HAMILL, LLC 0.19% of their portfolio | 160.3k $10.1m | New |
| Rafferty Asset Management, LLC 0.04% of their portfolio | 158.4k $9.9m | Reduced -5.5k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 152.3k $9.6m | Added +77.2k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 150.1k $9.4m | Added +18.0k |
| Moody Aldrich Partners LLC 1.67% of their portfolio | 147.9k $9.3m | Added +7.8k |
| Swiss National Bank 0.01% of their portfolio | 147.9k $9.3m | Reduced -6.6k |
| Schonfeld Strategic Advisors LLC 0.07% of their portfolio | 133.3k $8.4m | Reduced -132.7k |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 130.6k $8.2m | Added +241 |
| ACUTA CAPITAL PARTNERS, LLC 4.15% of their portfolio | 117.4k $7.4m | Reduced -3.6k |
| Walleye Capital LLC 0.10% of their portfolio | 113.9k $7.2m | New |
| Nicholas Investment Partners, LP 0.81% of their portfolio | 110.7k $7.0m | Reduced -349.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 105.1k $6.6m | Added +12.2k |
| SEI INVESTMENTS CO 0.01% of their portfolio | 103.3k $6.5m | Reduced -18.1k |
| California Public Employees Retirement System 0.00% of their portfolio | 98.1k $6.2m | Reduced -5.0k |
| CREDIT SUISSE AG/ 0.01% of their portfolio | 97.8k $6.1m | Added +11.6k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 91.2k $5.7m | Reduced -36.5k |
| Opaleye Management Inc. 1.50% of their portfolio | 90.0k $5.7m | Unchanged |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 86.2k $5.4m | Added +20.0k |
| CASTLEARK MANAGEMENT LLC 0.24% of their portfolio | 85.3k $5.4m | Added +28.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 82.3k $5.2m | Reduced -537 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 81.5k $5.1m | Added +7.0k |
| Legal & General Group Plc 0.00% of their portfolio | 80.0k $5.0m | Added +4.6k |
| CITIGROUP INC 0.01% of their portfolio | 78.9k $5.0m | Reduced -16.5k |
| FIRST TRUST ADVISORS LP 0.01% of their portfolio | 77.6k $4.9m | Added +44.9k |
| Ghost Tree Capital, LLC 2.53% of their portfolio | 70.0k $4.4m | Reduced -70.0k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 69.9k $4.4m | New |
| ALPS ADVISORS INC 0.03% of their portfolio | 65.3k $4.1m | Reduced -4.0k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 57.2k $3.6m | Reduced -12.8k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 54.6k $3.4m | Added +1.2k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 51.6k $3.2m | Reduced -2.4k |
| Mirae Asset Global Investments Co., Ltd. 0.01% of their portfolio | 51.1k $3.2m | Added +296 |
| Laurion Capital Management LP 0.11% of their portfolio | 50.0k $3.1m | Unchanged |
| MetLife Investment Management, LLC 0.02% of their portfolio | 49.3k $3.1m | Unchanged |