Vault-13

UNITED THERAPEUTICS CORP DEL UTHR

COM · Common Stock · CUSIP 91307C102 · ISIN US91307C1027

Biotech company based in Silver Spring, Maryland, United States

838 institutional holders +130 vs Q3 2025
42,081,18042.1m shares reported held*
97.7% of all shares outstanding*
$20.5bnreported value*
154 new 281 added 259 reduced 53 sold out net bought ≈ $213.1m (+451.6k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($46.1m this quarter). Holder counts are more reliable. Shares outstanding: 43.1m as of 2025-10-22, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $486.33. Options: 14 managers hold calls ($390.2m notional), 15 hold puts ($351.8m).

Trends to Q4 2025

Institutional holders

Managers reporting a position, each quarter

05001kQ3 22: 460Q4 22: 512Q1 23: 508Q2 23: 476Q3 23: 510Q4 23: 536Q1 24: 524Q2 24: 568Q3 24: 627Q4 24: 674Q1 25: 673Q2 25: 672Q3 25: 708Q4 25: 838838Q3 22Q2 23Q1 24Q4 24Q4 25
Numbers
QuarterHolders
Q3 2022460
Q4 2022512
Q1 2023508
Q2 2023476
Q3 2023510
Q4 2023536
Q1 2024524
Q2 2024568
Q3 2024627
Q4 2024674
Q1 2025673
Q2 2025672
Q3 2025708
Q4 2025838

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
5000500Q1 24: 265 bought or addedQ1 24: 243 cut or sold outQ2 24: 295 bought or addedQ2 24: 249 cut or sold outQ2 24Q3 24: 302 bought or addedQ3 24: 274 cut or sold outQ4 24: 340 bought or addedQ4 24: 255 cut or sold outQ4 24Q1 25: 333 bought or addedQ1 25: 310 cut or sold outQ2 25: 350 bought or addedQ2 25: 291 cut or sold outQ2 25Q3 25: 319 bought or addedQ3 25: 350 cut or sold outQ4 25: 435 bought or addedQ4 25: 312 cut or sold outQ4 25
Numbers
QuarterBought or addedCut or sold out
Q1 2024265243
Q2 2024295249
Q3 2024302274
Q4 2024340255
Q1 2025333310
Q2 2025350291
Q3 2025319350
Q4 2025435312

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500m$1bn$1.5bnQ1 25 calls: $43.4mQ1 25 puts: $44.7mQ1 25P/C 1.03Q2 25 calls: $133.5mQ2 25 puts: $104.6mQ2 25P/C 0.78Q3 25 calls: $623.8mQ3 25 puts: $1.3bnQ3 25P/C 2.03Q4 25 calls: $390.2mQ4 25 puts: $351.8mQ4 25P/C 0.90
Numbers
QuarterCallsPutsP/C
Q1 2025$43.4m$44.7m1.03
Q2 2025$133.5m$104.6m0.78
Q3 2025$623.8m$1.3bn2.03
Q4 2025$390.2m$351.8m0.90

Biggest buyers

WELLINGTON MANAGEMENT GROUP LLP Added +1,042,711+1.0m
Avoro Capital Advisors LLC Added +583,838+583.8k
JANUS HENDERSON GROUP PLC Added +341,383+341.4k
BAILLIE GIFFORD & CO New +323,016+323.0k
AQR CAPITAL MANAGEMENT LLC Added +295,221+295.2k
FULLER & THALER ASSET MANAGEMENT, INC. Added +265,921+265.9k
D. E. Shaw & Co., Inc. Added +242,260+242.3k
Caisse de depot et placement du Quebec Added +198,183+198.2k
JANE STREET GROUP, LLC Added +169,644+169.6k
FMR LLC Added +153,499+153.5k

Biggest sellers

Darwin Global Management, Ltd. Sold out -748,550-748.5k
CITIGROUP INC Reduced -367,062-367.1k
LSV ASSET MANAGEMENT Reduced -278,645-278.6k
RENAISSANCE TECHNOLOGIES LLC Reduced -264,133-264.1k
VANGUARD GROUP INC Reduced -242,594-242.6k
JPMORGAN CHASE & CO Reduced -233,659-233.7k
MILLENNIUM MANAGEMENT LLC Reduced -194,504-194.5k
BlackRock, Inc. Reduced -182,230-182.2k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -162,839-162.8k
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP Reduced -139,168-139.2k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $148.7m305.1k shares
Caption Management, LLC Reduced $108.6m222.8k shares
JANE STREET GROUP, LLC Unchanged $49.7m102.1k shares
CITADEL ADVISORS LLC Reduced $33.4m68.5k shares
IMC-Chicago, LLC Added $29.6m60.8k shares
NOMURA HOLDINGS INC Added $12.9m26.5k shares
Walleye Trading LLC Reduced $4.2m8.6k shares
GROUP ONE TRADING LLC Reduced $633.4k1.3k shares
TUDOR INVESTMENT CORP ET AL Added $584.7k1.2k shares
D. E. Shaw & Co., Inc. Reduced $584.7k1.2k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $88.9m182.5k shares
Caption Management, LLC Reduced $77.9m159.8k shares
JANE STREET GROUP, LLC Reduced $51.7m106.2k shares
NOMURA HOLDINGS INC Reduced $31.3m64.3k shares
CITADEL ADVISORS LLC Reduced $24.4m50.0k shares
IMC-Chicago, LLC Added $22.3m45.8k shares
LMR Partners LLP Reduced $21.8m44.7k shares
CITIGROUP INC Reduced $9.7m20.0k shares
Walleye Trading LLC Reduced $8.9m18.2k shares
DLD Asset Management, LP Added $6.1m12.5k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
ROTHBLATT MARTINE A 13G · exempt (held before listing) filed 2026-08-14 5.3% 2.3m≈ $1.3bn 2026-08-14
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.2% new 2.3m≈ $1.2bn 2026-04-30

Fell to 5% or below in the last year: WELLINGTON MANAGEMENT GROUP LLP (3.2%, 2026-08-13), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)

Insider purchases and sales in Q4 2025

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q1 24: 0 buyingQ1 24: 5 sellingQ2 24: 0 buyingQ2 24: 9 sellingQ2 24Q3 24: 0 buyingQ3 24: 6 sellingQ4 24: 0 buyingQ4 24: 8 sellingQ4 24Q1 25: 0 buyingQ1 25: 4 sellingQ2 25: 0 buyingQ2 25: 6 sellingQ2 25Q3 25: 0 buyingQ3 25: 7 sellingQ4 25: 0 buyingQ4 25: 9 sellingQ4 25
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q1 20240—5$76.0m$74.3m
Q2 20240—9$101.4m$79.0m
Q3 20240—6$77.2m$65.3m
Q4 20240—8$81.6m$61.4m
Q1 20250—4$42.3m$35.9m
Q2 20250—6$35.2m$33.4m
Q3 20250—7$98.3m$91.6m
Q4 20250—9$340.7m$336.6m
DateInsiderTradeSharesPrice ValueTheir holding
2025-12-29 BENKOWITZ MICHAEL PRESIDENT AND COO · by Trust Sold plan 22,500 $502.79 $11.3m22.5k shares -100%
2025-12-24 MAHON PAUL A EVP & GENERAL COUNSEL Sold plan 11,000 $513.18 $5.6m11.0k shares -23%
2025-12-23 MALCOLM JAN Director Sold plan 50 $512.12 $25.6k50 shares -11%
2025-12-22 BENKOWITZ MICHAEL PRESIDENT AND COO · by Trust Sold plan 22,500 $514.36 $11.6m22.5k shares -100%
2025-12-22 SULLIVAN LOUIS W Director · by Trust Sold 5,950 $512.14 $3.0m6.0k shares -100%
2025-12-19 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 2,000 $507.07 $1.0m2.0k shares -94%
2025-12-18 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $508.87 $2.0m4.0k shares -97%
2025-12-18 Thompson Tommy G Director Sold 910 $500.59 $455.5k910 shares -10%
2025-12-17 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $501.04 $2.0m4.0k shares -97%
2025-12-16 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $493.45 $2.0m4.0k shares -97%
2025-12-15 BENKOWITZ MICHAEL PRESIDENT AND COO · by Trust Sold plan 22,500 $496.30 $11.2m22.5k shares -100%
2025-12-15 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $494.72 $2.0m4.0k shares -97%
2025-12-15 EDGEMOND JAMES CFO AND TREASURER Sold plan 3,517 $495.36 $1.7m3.5k shares -30%
2025-12-15 PATUSKY CHRISTOPHER Director Sold 1,000 $495.95 $495.9k1.0k shares -40%
2025-12-12 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $490.70 $2.0m4.0k shares -97%
2025-12-11 MAHON PAUL A EVP & GENERAL COUNSEL Sold plan 11,000 $484.67 $5.3m11.0k shares -23%
2025-12-11 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $483.97 $1.9m4.0k shares -97%
2025-12-11 MALCOLM JAN Director Sold plan 50 $482.98 $24.1k50 shares -10%
2025-12-10 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $480.05 $1.9m4.0k shares -97%
2025-12-09 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $478.29 $1.9m4.0k shares -97%
2025-12-09 Mesa Nilda Director Sold 187 $481.63 $90.1k187 shares -3%
2025-12-08 BENKOWITZ MICHAEL PRESIDENT AND COO · by Trust Sold plan 22,500 $478.58 $10.8m22.5k shares -100%
2025-12-08 EDGEMOND JAMES CFO AND TREASURER Sold plan 21,000 $478.60 $10.1m21.0k shares -72%
2025-12-08 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $484.23 $1.9m4.0k shares -97%
2025-12-05 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $483.28 $1.9m4.0k shares -97%
2025-12-04 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $480.01 $1.9m4.0k shares -97%
2025-12-03 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $475.27 $1.9m4.0k shares -97%
2025-12-02 ROTHBLATT MARTINE A Chairperson & CEO, director Sold plan 4,000 $481.28 $1.9m4.0k shares -97%
2025-12-01 BENKOWITZ MICHAEL PRESIDENT AND COO · by Trust Sold plan 22,500 $479.92 $10.8m22.5k shares -100%
2025-12-01 EDGEMOND JAMES CFO AND TREASURER Sold plan 21,000 $479.99 $10.1m21.0k shares -72%

The latest 30 of 90 trades.

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q4 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 BlackRock, Inc. 0.04% of their portfolio New York, NY 5,170,7665.2m $2.5bn $2.5bn 0.04% Reduced -182.2k -182,230
2 VANGUARD GROUP INC 0.03% of their portfolio Valley Forge, PA 4,176,0164.2m $2.0bn $2.0bn 0.03% Reduced -242.6k -242,594
3 Avoro Capital Advisors LLC 12.48% of their portfolio NEW YORK, NY 2,606,0602.6m $1.3bn $1.3bn 12.48% Added +583.8k +583,838
4 WELLINGTON MANAGEMENT GROUP LLP 0.21% of their portfolio Boston, MA 2,441,4922.4m $1.2bn $1.2bn 0.21% Added +1.0m +1,042,711
5 RENAISSANCE TECHNOLOGIES LLC 1.44% of their portfolio NEW YORK, NY 1,909,2591.9m $930.3m $930.3m 1.44% Reduced -264.1k -264,133
6 STATE STREET CORP 0.03% of their portfolio BOSTON, MA 1,842,4111.8m $897.7m $897.7m 0.03% Reduced -80.2k -80,198
7 AQR CAPITAL MANAGEMENT LLC 0.33% of their portfolio Greenwich, CT 1,281,6991.3m $624.5m $624.5m 0.33% Added +295.2k +295,221
8 GEODE CAPITAL MANAGEMENT, LLC 0.04% of their portfolio BOSTON, MA 1,193,0641.2m $580.2m $580.2m 0.04% Reduced -56.6k -56,596
9 JANUS HENDERSON GROUP PLC 0.17% of their portfolio LONDON, X0 796,101796.1k $387.8m $387.8m 0.17% Added +341.4k +341,383
10 ASSETMARK, INC 0.63% of their portfolio CONCORD, CA 634,956635.0k $309.4m $309.4m 0.63% Reduced -11.0k -10,952
11 Invesco Ltd. 0.03% of their portfolio ATLANTA, GA 608,759608.8k $296.6m $296.6m 0.03% Reduced -28.5k -28,464
12 NORGES BANK 0.03% of their portfolio OSLO, Q8 602,191602.2k $293.4m $293.4m 0.03% Not comparable
13 FULLER & THALER ASSET MANAGEMENT, INC. 0.48% of their portfolio SAN MATEO, CA 581,226581.2k $283.2m $283.2m 0.48% Added +265.9k +265,921
14 DIMENSIONAL FUND ADVISORS LP 0.05% of their portfolio AUSTIN, TX 528,210528.2k $257.4m $257.4m 0.05% Added +15.4k +15,394
15 DEERFIELD MANAGEMENT COMPANY, L.P. 2.66% of their portfolio New York, NY 425,993426.0k $207.6m $207.6m 2.66% Unchanged
16 NORTHERN TRUST CORP 0.03% of their portfolio CHICAGO, IL 418,427418.4k $203.9m $203.9m 0.03% Reduced -28.6k -28,591
17 LSV ASSET MANAGEMENT 0.43% of their portfolio CHICAGO, IL 408,065408.1k $198.8m $198.8m 0.43% Reduced -278.6k -278,645
18 FMR LLC 0.01% of their portfolio BOSTON, MA 403,830403.8k $196.8m $196.8m 0.01% Added +153.5k +153,499
19 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 389,275389.3k $189.7m $189.7m 0.01% Reduced -49.5k -49,529
20 PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio BALTIMORE, MD 352,086352.1k $171.6m $171.6m 0.02% Added +51.2k +51,155
21 Bank of New York Mellon Corp 0.03% of their portfolio NEW YORK, NY 333,629333.6k $162.6m $162.6m 0.03% Reduced -17.8k -17,826
22 Swedbank AB 0.15% of their portfolio STOCKHOLM, V7 324,772324.8k $158.2m $158.2m 0.15% Reduced -4.3k -4,346
23 BAILLIE GIFFORD & CO 0.13% of their portfolio EDINBURGH, X0 323,016323.0k $157.4m $157.4m 0.13% New
24 D. E. Shaw & Co., Inc. 0.11% of their portfolio New York, NY 306,971307.0k $149.6m $149.6m 0.11% Added +242.3k +242,260
25 Pictet Asset Management Holding SA 0.15% of their portfolio CAROUGE, V8 306,837306.8k $149.7m $149.7m 0.15% Reduced -14.7k -14,658
26 Caisse de depot et placement du Quebec 0.24% of their portfolio Montreal, A8 296,320296.3k $144.4m $144.4m 0.24% Added +198.2k +198,183
27 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio SAN FRANCISCO, CA 289,926289.9k $141.3m $141.3m 0.02% Reduced -23.0k -23,022
28 HSBC HOLDINGS PLC 0.04% of their portfolio LONDON, X0 287,248287.2k $140.1m $140.1m 0.04% Added +130.9k +130,881
29 JPMORGAN CHASE & CO 0.01% of their portfolio NEW YORK, NY 262,215262.2k $127.8m $127.8m 0.01% Reduced -233.7k -233,659
30 LORD, ABBETT & CO. LLC 0.39% of their portfolio JERSEY CITY, NJ 258,049258.0k $125.7m $125.7m 0.39% Reduced -11.0k -11,023
31 Eversept Partners, LP 6.90% of their portfolio NEW YORK, NY 252,592252.6k $123.1m $123.1m 6.90% Reduced -628 -628
32 Nuveen, LLC 0.03% of their portfolio CHARLOTTE, NC 251,809251.8k $122.7m $122.7m 0.03% Reduced -35.3k -35,258
33 Pacer Advisors, Inc. 0.31% of their portfolio Malvern, PA 241,872241.9k $117.9m $117.9m 0.31% Reduced -97.2k -97,199
34 VICTORY CAPITAL MANAGEMENT INC 0.06% of their portfolio San Antonio, TX 228,383228.4k $111.3m $111.3m 0.06% Added +118.6k +118,628
35 UBS Group AG 0.02% of their portfolio ZURICH, V8 225,849225.8k $110.0m $110.0m 0.02% Added +70.4k +70,445
36 FIRST TRUST ADVISORS LP 0.08% of their portfolio Wheaton, IL 219,023219.0k $106.7m $106.7m 0.08% Reduced -81.5k -81,472
37 JANE STREET GROUP, LLC 0.13% of their portfolio NEW YORK, NY 216,820216.8k $105.6m $105.6m 0.13% Added +169.6k +169,644
38 ALLIANCEBERNSTEIN L.P. 0.03% of their portfolio NASHVILLE, TN 206,543206.5k $100.6m $100.6m 0.03% Added +26.1k +26,141
39 BANK OF AMERICA CORP /DE/ 0.01% of their portfolio CHARLOTTE, NC 205,131205.1k $100.0m $100.0m 0.01% Added +12.3k +12,287
40 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio NEW YORK, NY 203,351203.4k $99.1m $99.1m 0.02% Added +158 +158
41 ACADIAN ASSET MANAGEMENT LLC 0.16% of their portfolio Boston, MA 200,531200.5k $97.7m $97.7m 0.16% Added +60.7k +60,674
42 CITADEL ADVISORS LLC 0.06% of their portfolio MIAMI, FL 187,164187.2k $91.2m $91.2m 0.06% Reduced -86.8k -86,818
43 Point72 Asset Management, L.P. 0.14% of their portfolio STAMFORD, CT 186,164186.2k $90.7m $90.7m 0.14% Added +86.4k +86,380
44 CITIGROUP INC 0.06% of their portfolio NEW YORK, NY 184,408184.4k $89.9m $89.9m 0.06% Reduced -367.1k -367,062
45 FRONTIER CAPITAL MANAGEMENT CO LLC 0.94% of their portfolio Boston, MA 181,177181.2k $88.3m $88.3m 0.94% Added +7.2k +7,229
46 FRANKLIN RESOURCES INC 0.02% of their portfolio San Mateo, CA 181,120181.1k $88.3m $88.3m 0.02% Added +118.5k +118,454
47 Legal & General Group Plc 0.02% of their portfolio London, X0 173,592173.6k $84.6m $84.6m 0.02% Reduced -26.1k -26,064
48 Amundi 0.02% of their portfolio Paris, I0 163,194163.2k $79.5m $79.5m 0.02% Added +33.2k +33,209
49 COMERICA BANK 0.31% of their portfolio DALLAS, TX 161,683161.7k $78.8m $78.8m 0.31% Added +3.7k +3,731
50 Sofinnova Investments, Inc. 3.31% of their portfolio Menlo Park, CA 157,641157.6k $76.8m $76.8m 3.31% Reduced -33.0k -32,985
51 SEIZERT CAPITAL PARTNERS, LLC 3.00% of their portfolio BIRMINGHAM, MI 145,522145.5k $70.9m $70.9m 3.00% Reduced -1.5k -1,469
52 Epoch Investment Partners, Inc. 0.39% of their portfolio New York, NY 142,292142.3k $69.3m $69.3m 0.39% Reduced -63.5k -63,490
53 Candriam S.C.A. 0.31% of their portfolio STRASSEN, N4 127,215127.2k $62.0m $62.0m 0.31% Added +3.8k +3,828
54 DEUTSCHE BANK AG\ 0.02% of their portfolio FRANKFURT AM MAIN, 2M 124,475124.5k $60.7m $60.7m 0.02% Added +5.4k +5,429
55 RHUMBLINE ADVISERS 0.05% of their portfolio BOSTON, MA 121,751121.8k $59.3m $59.3m 0.05% Reduced -7.1k -7,078
56 Tri Locum Partners LP 7.65% of their portfolio NEW YORK, NY 120,921120.9k $58.9m $58.9m 7.65% Reduced -1.3k -1,266
57 Thrivent Financial for Lutherans 0.10% of their portfolio Minneapolis, MN 120,802120.8k $58.9m $58.9m 0.10% Reduced -56.0k -55,985
58 Swiss National Bank 0.03% of their portfolio ZURICH, V8 117,735117.7k $57.4m $57.4m 0.03% Reduced -5.7k -5,720
59 Robeco Institutional Asset Management B.V. 0.08% of their portfolio ROTTERDAM, P7 113,850113.8k $55.5m $55.5m 0.08% Added +22.8k +22,751
60 TD Asset Management Inc 0.04% of their portfolio Toronto, A6 113,135113.1k $55.1m $55.1m 0.04% Reduced -25.7k -25,724
61 GOLDMAN SACHS GROUP INC 0.01% of their portfolio NEW YORK, NY 110,774110.8k $54.0m $54.0m 0.01% Added +29.2k +29,238
62 ORBIMED ADVISORS LLC 1.05% of their portfolio New York, NY 105,200105.2k $51.3m $51.3m 1.05% Reduced -9.7k -9,700
63 Allspring Global Investments Holdings, LLC 0.08% of their portfolio CHARLOTTE, NC 104,785104.8k $52.0m $52.0m 0.08% Added +15.0k +14,976
64 Polaris Capital Management, LLC 4.19% of their portfolio BOSTON, MA 103,650103.7k $50.5m $50.5m 4.19% Reduced -18.4k -18,400
65 AMERIPRISE FINANCIAL INC 0.01% of their portfolio MINNEAPOLIS, MN 101,042101.0k $49.2m $49.2m 0.01% Added +37.7k +37,661
66 Qube Research & Technologies Ltd 0.07% of their portfolio LONDON, X0 98,30498.3k $47.9m $47.9m 0.07% Added +68.7k +68,705
67 PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio DES MOINES, IA 98,15898.2k $47.8m $47.8m 0.02% Reduced -7.6k -7,609
68 Retirement Systems of Alabama 0.15% of their portfolio MONTGOMERY, AL 97,26897.3k $47.4m $47.4m 0.15% Reduced -3.0k -3,005
69 STOREBRAND ASSET MANAGEMENT AS 0.12% of their portfolio LYSAKER, Q8 93,80493.8k $45.7m $45.7m 0.12% Added +11.1k +11,062
70 DekaBank Deutsche Girozentrale 0.04% of their portfolio FRANKFURT, 2M 93,53293.5k $24.2m $24.2m 0.04% Unchanged
71 Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio CHIYODA-KU, TOKYO, M0 92,15692.2k $44.9m $44.9m 0.03% Reduced -2.5k -2,546
72 Krensavage Asset Management, LLC 15.71% of their portfolio NEW YORK, NY 91,28291.3k $44.5m $44.5m 15.71% Reduced -6.4k -6,364
73 WELLS FARGO & COMPANY/MN 0.01% of their portfolio SAN FRANCISCO, CA 90,94090.9k $44.3m $44.3m 0.01% Added +12.8k +12,819
74 BARCLAYS PLC 0.02% of their portfolio LONDON, X0 90,92590.9k $44.3m $44.3m 0.02% Reduced -21.9k -21,921
75 California Public Employees Retirement System 0.02% of their portfolio Sacramento, CA 83,35683.4k $40.6m $40.6m 0.02% Reduced -63.3k -63,307
76 Gotham Asset Management, LLC 0.14% of their portfolio NEW YORK, NY 80,01880.0k $39.0m $39.0m 0.14% Reduced -939 -939
77 Man Group plc 0.07% of their portfolio LONDON, X0 79,00279.0k $38.5m $38.5m 0.07% Added +16.0k +15,953
78 Corient Private Wealth LP 0.01% of their portfolio MIAMI, FL 73,01973.0k $17.8m $17.8m 0.01% Added +56.1k +56,060
79 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.02% of their portfolio BOSTON, MA 69,36769.4k $33.8m $33.8m 0.02% Reduced -139.2k -139,168
80 AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio KANSAS CITY, MO 67,95768.0k $33.1m $33.1m 0.02% Added +31.8k +31,828
81 PFM Health Sciences, LP 3.34% of their portfolio SAN FRANCISCO, CA 67,74367.7k $33.0m $33.0m 3.34% Reduced -27.9k -27,907
82 Bridgewater Associates, LP 0.11% of their portfolio Westport, CT 64,59564.6k $31.5m $31.5m 0.11% Added +48.5k +48,530
83 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.04% of their portfolio Paris, I0 64,53764.5k $31.5m $31.5m 0.04% New
84 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 64,07364.1k $31.2m $31.2m 0.02% Reduced -194.5k -194,504
85 First Turn Management, LLC 3.54% of their portfolio DEL MAR, CA 63,58063.6k $31.0m $31.0m 3.54% Reduced -21.7k -21,738
86 ATWOOD & PALMER INC 1.76% of their portfolio KANSAS CITY, MO 63,53263.5k $31.0m $31.0m 1.76% Reduced -348 -348
87 HRT FINANCIAL LP 0.12% of their portfolio NEW YORK, NY 63,39763.4k $30.9m $30.9m 0.12% Reduced -12.2k -12,241
88 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio WEST SACRAMENTO, CA 63,30463.3k $30.8m $30.8m 0.03% Reduced -881 -881
89 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.02% of their portfolio Toronto, A6 61,70061.7k $30.3m $30.3m 0.02% Reduced -591 -591
90 TOCQUEVILLE ASSET MANAGEMENT L.P. 0.43% of their portfolio New York, NY 61,14361.1k $29.8m $29.8m 0.43% Reduced -599 -599
91 WEDGE CAPITAL MANAGEMENT L L P/NC 0.53% of their portfolio CHARLOTTE, NC 60,68760.7k $29.6m $29.6m 0.53% Reduced -5.9k -5,865
92 Soleus Capital Management, L.P. 1.24% of their portfolio GREENWICH, CT 60,00060.0k $29.2m $29.2m 1.24% Reduced -90.0k -90,000
93 IEQ CAPITAL, LLC 0.09% of their portfolio Foster City, CA 58,95959.0k $28.7m $28.7m 0.09% Added +46.7k +46,714
94 Palo Alto Investors LP 3.95% of their portfolio PALO ALTO, CA 58,18658.2k $28.4m $28.4m 3.95% Unchanged
95 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 57,28857.3k $27.9m $27.9m 0.00% Added +20.9k +20,856
96 Summit Street Capital Management, LLC 4.36% of their portfolio NEW YORK, NY 56,87256.9k $27.7m $27.7m 4.36% Reduced -10.3k -10,281
97 Balyasny Asset Management L.P. 0.05% of their portfolio Chicago, IL 55,93455.9k $27.3m $27.3m 0.05% Reduced -91.0k -90,964
98 Caption Management, LLC 1.18% of their portfolio OKLAHOMA CITY, OK 55,08155.1k $26.8m $26.8m 1.18% Added +15.6k +15,562
99 Russell Investments Group, Ltd. 0.03% of their portfolio Seattle, WA 54,81154.8k $26.8m $26.8m 0.03% Added +11.9k +11,935
100 Zurcher Kantonalbank (Zurich Cantonalbank) 0.05% of their portfolio ZURICH, V8 52,01252.0k $25.3m $25.3m 0.05% Added +32.7k +32,689