Vault-13

2SEVENTY BIO INC TSVT

COMMON STOCK · Common Stock · CUSIP 901384107 · ISIN US9013841070

116 institutional holders -2 vs Q1 2024
48,167,26848.2m shares reported held*
$185.5mreported value*
16 new 37 added 30 reduced 20 sold out net sold ≈ $32.5m (-8.5m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $3.85. Options: 5 managers hold calls ($1.1m notional), 3 hold puts ($42.3k).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 134Q4 22: 143Q1 23: 148Q2 23: 151Q3 23: 147Q4 23: 117Q1 24: 118Q2 24: 116116Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 2022134
Q4 2022143
Q1 2023148
Q2 2023151
Q3 2023147
Q4 2023117
Q1 2024118
Q2 2024116

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 67 bought or addedQ4 22: 50 cut or sold outQ4 22Q1 23: 86 bought or addedQ1 23: 45 cut or sold outQ2 23: 84 bought or addedQ2 23: 51 cut or sold outQ2 23Q3 23: 78 bought or addedQ3 23: 57 cut or sold outQ4 23: 45 bought or addedQ4 23: 78 cut or sold outQ4 23Q1 24: 45 bought or addedQ1 24: 60 cut or sold outQ2 24: 53 bought or addedQ2 24: 50 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20226750
Q1 20238645
Q2 20238451
Q3 20237857
Q4 20234578
Q1 20244560
Q2 20245350

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500k$1m$1.5mQ3 23 calls: $49.6kQ3 23 puts: $95.9kQ3 23P/C 1.93Q4 23 calls: $452.5kQ4 23 puts: $1.2mQ4 23P/C 2.62Q1 24 calls: $707.1kQ1 24 puts: $1.3mQ1 24P/C 1.78Q2 24 calls: $1.1mQ2 24 puts: $42.3kQ2 24P/C 0.04
Numbers
QuarterCallsPutsP/C
Q3 2023$49.6k$95.9k1.93
Q4 2023$452.5k$1.2m2.62
Q1 2024$707.1k$1.3m1.78
Q2 2024$1.1m$42.3k0.04

Biggest buyers

Newtyn Management, LLC New +2,485,000+2.5m
DEUTSCHE BANK AG\ Added +1,762,444+1.8m
Fund 1 Investments, LLC New +388,416+388.4k
MARSHALL WACE, LLP Added +223,408+223.4k
Venator Management LLC Added +160,000+160.0k
Madison Avenue Partners, LP Added +130,000+130.0k
Stonepine Capital Management, LLC New +100,000+100.0k
BANK OF AMERICA CORP /DE/ Added +76,713+76.7k
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC Added +54,076+54.1k
BARCLAYS PLC Added +45,891+45.9k

Biggest sellers

MORGAN STANLEY Reduced -9,801,624-9.8m
Point72 Asset Management, L.P. Sold out -1,612,542-1.6m
JPMORGAN CHASE & CO Reduced -862,560-862.6k
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND Reduced -268,100-268.1k
BlackRock Inc. Reduced -244,382-244.4k
JACOBS LEVY EQUITY MANAGEMENT, INC Reduced -233,271-233.3k
MILLENNIUM MANAGEMENT LLC Reduced -200,348-200.3k
CHARLES SCHWAB INVESTMENT MANAGEMENT INC Reduced -165,247-165.2k
DAFNA Capital Management LLC Reduced -153,342-153.3k
Mirae Asset Global Investments Co., Ltd. Sold out -146,901-146.9k

Biggest calls

ExodusPoint Capital Management, LP New $770.0k200.0k shares
GROUP ONE TRADING LLC Added $184.4k47.9k shares
SIMPLEX TRADING, LLC Added $68.0k17.8k shares
CITADEL ADVISORS LLC Reduced $42.7k11.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITADEL ADVISORS LLC Reduced $37.3k9.7k shares
SIMPLEX TRADING, LLC Reduced $5.0k1.5k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
VANGUARD GROUP INC 13G · institution filed 2025-04-30 5.4% 2.8m 2025-04-30

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Kynam Capital Management, LP 2.40% of their portfolio PRINCETON, NJ 5,953,8256.0m $22.9m $22.9m 2.40% Unchanged
2 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 4,137,8454.1m $15.9m $15.9m 0.00% Reduced -83.9k -83,938
3 BlackRock Inc. 0.00% of their portfolio New York, NY 3,661,0233.7m $14.1m $14.1m 0.00% Reduced -244.4k -244,382
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 3,629,1213.6m $14.0m $14.0m 0.00% Reduced -102.6k -102,558
5 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 3,270,8943.3m $12.6m $12.6m 0.00% Reduced -9.8m -9,801,624
6 Madison Avenue Partners, LP 1.25% of their portfolio NEW YORK, NY 2,563,2222.6m $9.9m $9.9m 1.25% Added +130.0k +130,000
7 BAKER BROS. ADVISORS LP 0.12% of their portfolio NEW YORK, NY 2,497,5262.5m $9.6m $9.6m 0.12% Unchanged
8 Newtyn Management, LLC 1.80% of their portfolio NEW YORK, NY 2,485,0002.5m $9.6m $9.6m 1.80% New
9 Casdin Capital, LLC 0.59% of their portfolio New York, NY 2,000,0002.0m $7.7m $7.7m 0.59% Unchanged
10 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 1,784,6191.8m $6.9m $6.9m 0.00% Added +1.8m +1,762,444
11 Engine Capital Management, LP 1.08% of their portfolio NEW YORK, NY 1,494,3041.5m $5.8m $5.8m 1.08% Unchanged
12 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.02% of their portfolio TORONTO, A6 1,468,5001.5m $5.7m $5.7m 0.02% Reduced -268.1k -268,100
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,163,1001.2m $4.5m $4.5m 0.00% Added +20.1k +20,067
14 Eversept Partners, LP 0.33% of their portfolio NEW YORK, NY 1,107,7431.1m $4.3m $4.3m 0.33% Reduced -69.9k -69,935
15 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1,064,8641.1m $4.1m $4.1m 0.00% Reduced -862.6k -862,560
16 DAFNA Capital Management LLC 0.97% of their portfolio LOS ANGELES, CA 1,050,7091.1m $4.0m $4.0m 0.97% Reduced -153.3k -153,342
17 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,043,1351.0m $4.0m $4.0m 0.00% Added +42.6k +42,623
18 COWEN AND COMPANY, LLC 0.09% of their portfolio NEW YORK, NY 800,000800.0k $3.1m $3.1m 0.09% Unchanged
19 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 667,023667.0k $2.6m $2.6m 0.00% Added +223.4k +223,408
20 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 606,776606.8k $2.3m $2.3m 0.00% Added +76.7k +76,713
21 Venator Management LLC 0.56% of their portfolio PITTSBURGH, PA 485,000485.0k $1.9m $1.9m 0.56% Added +160.0k +160,000
22 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 475,085475.1k $1.8m $1.8m 0.00% Reduced -200.3k -200,348
23 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 449,278449.3k $1.7m $1.7m 0.00% Reduced -165.2k -165,247
24 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 413,969414.0k $1.6m $1.6m 0.00% Reduced -10.7k -10,687
25 Fund 1 Investments, LLC 0.21% of their portfolio RINCON, PR 388,416388.4k $1.5m $1.5m 0.21% New
26 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 240,367240.4k $925.4k $925.4k 0.00% Added +38.3k +38,294
27 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 212,613212.6k $818.6k $818.6k 0.00% Added +45.9k +45,891
28 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 204,845204.8k $788.5k $788.5k 0.00% Reduced -24.4k -24,371
29 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 196,959197.0k $758.3k $758.3k 0.00% Added +10.1k +10,077
30 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio BALA CYNWYD, PA 192,319192.3k $740.4k $740.4k 0.02% Added +54.1k +54,076
31 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 162,182162.2k $611.4k $611.4k 0.00% Reduced -7.7k -7,725
32 JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio FLORHAM PARK, NJ 146,315146.3k $563.3k $563.3k 0.00% Reduced -233.3k -233,271
33 FMR LLC 0.00% of their portfolio BOSTON, MA 121,807121.8k $469.0k $469.0k 0.00% Added +34.1k +34,116
34 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 116,847116.8k $449.9k $449.9k 0.00% First filing
35 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 111,700111.7k $430.0k $430.0k 0.01% Added +15.0k +15,000
36 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 110,329110.3k $424.8k $424.8k 0.00% Added +13.2k +13,150
37 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 108,016108.0k $415.9k $415.9k 0.00% Added +300 +300
38 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 104,374104.4k $401.8k $401.8k 0.00% Added +42.0k +41,974
39 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 100,882100.9k $388.4k $388.4k 0.00% Reduced -893 -893
40 Stonepine Capital Management, LLC 0.35% of their portfolio Bend, OR 100,000100.0k $385.0k $385.0k 0.35% New
41 HighVista Strategies LLC 0.13% of their portfolio BOSTON, MA 93,50093.5k $360.0k $360.0k 0.13% Unchanged
42 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 81,21881.2k $312.7k $312.7k 0.00% Reduced -444 -444
43 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 79,95380.0k $307.8k $307.8k 0.00% Added +11.4k +11,363
44 Wedmont Private Capital 0.02% of their portfolio WEST CHESTER, PA 77,93477.9k $346.0k $346.0k 0.02% Reduced -8.0k -8,000
45 HSBC HOLDINGS PLC 0.00% of their portfolio LONDON, X0 68,58968.6k $258.6k $258.6k 0.00% Added +393 +393
46 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 65,97666.0k $254.0k $254.0k 0.00% Added +16.7k +16,680
47 MARTINGALE ASSET MANAGEMENT L P 0.00% of their portfolio BOSTON, MA 58,15858.2k $223.9k $223.9k 0.00% Added +13.0k +13,000
48 SHERBROOKE PARK ADVISERS LLC 0.04% of their portfolio WHITE PLAINS, NY 55,02255.0k $211.8k $211.8k 0.04% Added +43.0k +43,046
49 EXCHANGE TRADED CONCEPTS, LLC 0.01% of their portfolio Oklahoma City, OK 54,88054.9k $211.3k $211.3k 0.01% Reduced -17.1k -17,073
50 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 52,59052.6k $202.5k $202.5k 0.00% Added +32.8k +32,815
51 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 41,97942.0k $161.6k $161.6k 0.00% Added +8.9k +8,944
52 Birchview Capital, LP 0.06% of their portfolio BURLINGTON, VT 35,66635.7k $137.3k $137.3k 0.06% Reduced -4.0k -4,000
53 Graham Capital Management, L.P. 0.00% of their portfolio ROWAYTON, CT 31,51731.5k $121.3k $121.3k 0.00% Added +19.2k +19,208
54 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 29,65929.7k $114.2k $114.2k 0.00% Added +12.9k +12,938
55 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 28,92928.9k $112.0k $112.0k 0.00% Unchanged
56 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 26,29426.3k $101.2k $101.2k 0.00% First filing
57 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio COLUMBUS, OH 25,80825.8k $99.4k $99.4k 0.00% Reduced -1.6k -1,562
58 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 25,43525.4k $97.9k $97.9k 0.00% Added +3.6k +3,582
59 ExodusPoint Capital Management, LP 0.00% of their portfolio NEW YORK, NY 25,16125.2k $97.0k $97.0k 0.00% New
60 BBR PARTNERS, LLC 0.01% of their portfolio NEW YORK, NY 25,00025.0k $96.2k $96.2k 0.01% Added +10.0k +10,000
61 BROWN WEALTH MANAGEMENT, LLC 0.04% of their portfolio NAPERVILLE, IL 25,00025.0k $96.2k $96.2k 0.04% Reduced -25.0k -25,000
62 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 19,65619.7k $75.7k $75.7k 0.00% Reduced -863 -863
63 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 19,00419.0k $73.2k $73.2k 0.00% Reduced -29.5k -29,514
64 BRIGHTON JONES LLC 0.00% of their portfolio SEATTLE, WA 18,43618.4k $71.0k $71.0k 0.00% Unchanged
65 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 17,35717.4k $66.8k $66.8k 0.00% Added +28 +28
66 HORIZON KINETICS ASSET MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 17,27517.3k $66.5k $66.5k 0.00% Unchanged
67 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 16,63416.6k $64.0k $64.0k 0.00% Added +582 +582
68 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 16,00016.0k $61.6k $61.6k 0.00% Added +1.4k +1,400
69 UBS Group AG 0.00% of their portfolio ZURICH, V8 15,34415.3k $59.1k $59.1k 0.00% Reduced -38.0k -38,020
70 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 15,15915.2k $58.4k $58.4k 0.00% Reduced -3.7k -3,672
71 Fiduciary Trust Co 0.00% of their portfolio Boston, MA 15,10315.1k $58.1k $58.1k 0.00% Unchanged
72 Mariner, LLC 0.00% of their portfolio Overland Park, KS 14,39614.4k $55.4k $55.4k 0.00% Reduced -100 -100
73 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 13,56113.6k $52.2k $52.2k 0.00% New
74 SkyView Investment Advisors, LLC 0.01% of their portfolio SHREWSBURY, NJ 12,50012.5k $48.0k $48.0k 0.01% Added +2.5k +2,500
75 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 11,42811.4k $44.0k $44.0k 0.00% Added +2.8k +2,757
76 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 8,2778.3k $31.9k $31.9k 0.00% Added +5.5k +5,540
77 Erste Asset Management GmbH 0.00% of their portfolio VIENNA, C4 4,9995.0k $18.8k $18.8k 0.00% Unchanged
78 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 4,5984.6k $18.0k $18.0k 0.00% Added +3.5k +3,452
79 Legal & General Group Plc 0.00% of their portfolio London, X0 4,3454.3k $16.7k $16.7k 0.00% Reduced -1.2k -1,240
80 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 4,1484.1k $16.0k $16.0k 0.00% Unchanged
81 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 3,5413.5k $13.6k $13.6k 0.00% Reduced -1.5k -1,509
82 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 3,3303.3k $12.8k $12.8k 0.00% Reduced -14.6k -14,606
83 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 2,8002.8k $10.8k $10.8k 0.00% Added +2.7k +2,724
84 nVerses Capital, LLC 0.01% of their portfolio WELLINGTON, FL 2,3002.3k $8.9k $8.9k 0.01% New
85 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 1,7631.8k $7.0k $7.0k 0.00% Added +465 +465
86 ADAR1 Capital Management, LLC 0.00% of their portfolio AUSTIN, TX 1,0001.0k $3.9k $3.9k 0.00% Unchanged
87 COMERICA BANK 0.00% of their portfolio DALLAS, TX 835835 $3.2k $3.2k 0.00% New
88 Larson Financial Group LLC 0.00% of their portfolio ST LOUIS, MO 698698 $2.7k $2.7k 0.00% Unchanged
89 Steward Partners Investment Advisory, LLC 0.00% of their portfolio STAMFORD, CT 539539 $2.1k $2.1k 0.00% Unchanged
90 FLPUTNAM INVESTMENT MANAGEMENT CO 0.00% of their portfolio PORTLAND, ME 437437 $1.7k $1.7k 0.00% New
91 PICTON MAHONEY ASSET MANAGEMENT 0.00% of their portfolio Toronto, A6 421421 $2.0k $2.0k 0.00% New
92 Redwood Wealth Management Group, LLC 0.00% of their portfolio MEDFORD, NJ 407407 $1.6k $1.6k 0.00% New
93 PNC Financial Services Group, Inc. 0.00% of their portfolio Pittsburgh, PA 406406 $1.6k $1.6k 0.00% Unchanged
94 LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 397397 $1.0k $1.0k 0.00% Reduced -7.1k -7,102
95 Activest Wealth Management 0.00% of their portfolio AVENTURA, FL 333333 $1.3k $1.3k 0.00% New
96 NewEdge Advisors, LLC 0.00% of their portfolio NEW ORLEANS, LA 195195 $751 $751 0.00% Unchanged
97 PFS Partners, LLC 0.00% of their portfolio MINE HILL, NJ 113113 $436 $436 0.00% Unchanged
98 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 100100 $385 $385 0.00% New
99 Halpern Financial, Inc. 0.00% of their portfolio ASHBURN, VA 100100 $385 $385 0.00% Unchanged
100 TRUST CO OF VERMONT 0.00% of their portfolio BRATTLEBORO, VT 8383 $320 $320 0.00% Unchanged