TG THERAPEUTICS INC TGTX
COM · Common Stock · CUSIP 88322Q108 · ISIN US88322Q1085
A commercial stage biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Websitetgtherapeutics.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($16.6m this quarter). Holder counts are more reliable. Shares outstanding: 158.7m as of 2025-08-05, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $35.89. Options: 21 managers hold calls ($105.6m notional), 20 hold puts ($77.0m).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 183 |
| Q4 2022 | 198 |
| Q1 2023 | 214 |
| Q2 2023 | 245 |
| Q3 2023 | 238 |
| Q4 2023 | 237 |
| Q1 2024 | 243 |
| Q2 2024 | 261 |
| Q3 2024 | 310 |
| Q4 2024 | 333 |
| Q1 2025 | 378 |
| Q2 2025 | 358 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 147 | 105 |
| Q4 2023 | 110 | 109 |
| Q1 2024 | 120 | 108 |
| Q2 2024 | 138 | 100 |
| Q3 2024 | 182 | 117 |
| Q4 2024 | 165 | 150 |
| Q1 2025 | 194 | 155 |
| Q2 2025 | 184 | 169 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $70.9m | $47.2m | 0.67 |
| Q4 2024 | $136.9m | $112.5m | 0.82 |
| Q1 2025 | $118.3m | $96.4m | 0.81 |
| Q2 2025 | $105.6m | $77.0m | 0.73 |
Biggest buyers
| ROYAL BANK OF CANADA | Added | +1.3m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.2m |
| Point72 Asset Management, L.P. | New | +717.5k |
| Balyasny Asset Management L.P. | New | +696.1k |
| LORD, ABBETT & CO. LLC | New | +558.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +548.5k |
| MILLENNIUM MANAGEMENT LLC | Added | +526.0k |
| Clearbridge Investments, LLC | Added | +408.1k |
| CITADEL ADVISORS LLC | Added | +398.6k |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | Added | +390.1k |
Biggest sellers
| 1832 Asset Management L.P. | Reduced | -1.3m |
| MORGAN STANLEY | Reduced | -647.9k |
| Soleus Capital Management, L.P. | Reduced | -602.8k |
| Pictet Asset Management Holding SA | Reduced | -489.7k |
| BNP PARIBAS FINANCIAL MARKETS | Reduced | -472.0k |
| JPMORGAN CHASE & CO | Reduced | -442.0k |
| GOLDMAN SACHS GROUP INC | Reduced | -349.5k |
| Squarepoint Ops LLC | Sold out | -319.2k |
| 683 Capital Management, LLC | Sold out | -295.0k |
| Invesco Ltd. | Reduced | -240.9k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $24.3m675.6k shares |
| CITADEL ADVISORS LLC | Reduced | $17.9m496.1k shares |
| WOLVERINE TRADING, LLC | Added | $9.8m266.2k shares |
| JANE STREET GROUP, LLC | Reduced | $9.0m249.2k shares |
| GROUP ONE TRADING LLC | Reduced | $8.6m238.5k shares |
| SIMPLEX TRADING, LLC | Added | $7.6m212.3k shares |
| IMC-Chicago, LLC | Added | $5.6m155.6k shares |
| UBS Group AG | New | $5.2m144.4k shares |
| D. E. Shaw & Co., Inc. | Added | $3.9m107.3k shares |
| Walleye Capital LLC | Added | $3.3m93.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $22.5m625.2k shares |
| CITADEL ADVISORS LLC | Reduced | $14.3m398.4k shares |
| JANE STREET GROUP, LLC | Reduced | $8.8m245.7k shares |
| GROUP ONE TRADING LLC | Reduced | $5.5m151.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $4.4m122.6k shares |
| WOLVERINE TRADING, LLC | Added | $3.7m100.2k shares |
| MIRAE ASSET SECURITIES (USA) INC. | Reduced | $3.6m100.0k shares |
| Walleye Capital LLC | Added | $3.0m83.9k shares |
| Twin Tree Management, LP | New | $2.8m78.6k shares |
| Walleye Trading LLC | Added | $2.3m64.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +1.0 pts · filed 2026-10-27 | 13.8% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 5.3% |
| STATE STREET CORP 13G · institution +0.4 pts · filed 2025-11-10 | 5.1% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 1 | $1.0m | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 3 | $1.6m | — |
| Q2 2024 | 0 | — | 1 | $432.9k | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 3 | $1.4m | — |
| Q1 2025 | 0 | — | 1 | $629.3k | — |
| Q2 2025 | 0 | — | 1 | $369.4k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-13 | Echelard Yann Director | Sold | $369.4k10.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.02% of their portfolio | 21.8m $785.1m | Added +318.3k |
| VANGUARD GROUP INC 0.01% of their portfolio | 15.8m $569.0m | Added +204.8k |
| STATE STREET CORP 0.01% of their portfolio | 7.6m $274.2m | Added +184.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 3.5m $126.0m | Added +207.9k |
| Clearbridge Investments, LLC 0.09% of their portfolio | 3.1m $109.9m | Added +408.1k |
| Soleus Capital Management, L.P. 5.58% of their portfolio | 2.2m $80.8m | Reduced -602.8k |
| Pictet Asset Management Holding SA 0.07% of their portfolio | 1.9m $68.7m | Reduced -489.7k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 1.6m $56.5m | Reduced -349.5k |
| Hood River Capital Management LLC 0.79% of their portfolio | 1.6m $56.4m | Added +11.0k |
| FMR LLC 0.00% of their portfolio | 1.6m $55.9m | Reduced -191.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 1.5m $55.7m | Added +1.2m |
| NORTHERN TRUST CORP 0.01% of their portfolio | 1.5m $55.3m | Added +6.3k |
| MORGAN STANLEY 0.00% of their portfolio | 1.4m $50.5m | Reduced -647.9k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.3m $48.5m | Added +1.3m |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 1.3m $47.4m | Added +53.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio | 1.2m $44.3m | Added +16.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.07% of their portfolio | 1.2m $43.5m | Added +548.5k |
| CITADEL ADVISORS LLC 0.03% of their portfolio | 1.0m $37.6m | Added +398.6k |
| Invesco Ltd. 0.01% of their portfolio | 969.9k $34.9m | Reduced -240.9k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.60% of their portfolio | 954.5k $34.4m | Added +235.7k |
| Bank of New York Mellon Corp 0.01% of their portfolio | 906.5k $32.6m | Added +13.7k |
| Driehaus Capital Management LLC 0.23% of their portfolio | 807.8k $29.1m | Added +33.2k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 796.7k $28.7m | Reduced -44.3k |
| Point72 Asset Management, L.P. 0.06% of their portfolio | 717.5k $25.8m | New |
| JANE STREET GROUP, LLC 0.04% of their portfolio | 705.0k $25.4m | Added +345.8k |
| Balyasny Asset Management L.P. 0.06% of their portfolio | 696.1k $25.1m | New |
| CITIGROUP INC 0.02% of their portfolio | 686.0k $24.7m | Added +336.9k |
| RAYMOND JAMES FINANCIAL INC 0.01% of their portfolio | 678.8k $24.4m | Reduced -8.3k |
| Nuveen, LLC 0.01% of their portfolio | 657.2k $23.7m | Reduced -89.5k |
| BARCLAYS PLC 0.01% of their portfolio | 620.5k $22.3m | Added +367.5k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 615.7k $22.2m | Added +526.0k |
| TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio | 613.7k $22.1m | Reduced -179.9k |
| Woodline Partners LP 0.11% of their portfolio | 594.6k $21.4m | Added +61.5k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 567.4k $20.4m | Reduced -117.1k |
| LORD, ABBETT & CO. LLC 0.06% of their portfolio | 558.0k $20.1m | New |
| Opaleye Management Inc. 3.90% of their portfolio | 535.0k $19.3m | Unchanged |
| UBS Group AG 0.00% of their portfolio | 531.4k $19.1m | Reduced -100.2k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 525.2k $18.9m | Added +769 |
| BRAUN STACEY ASSOCIATES INC 0.67% of their portfolio | 518.0k $18.6m | Added +15.4k |
| GROUP ONE TRADING LLC 0.55% of their portfolio | 464.5k $16.7m | Added +162.9k |
| Public Sector Pension Investment Board 0.07% of their portfolio | 462.4k $16.6m | Added +39.0k |
| First Turn Management, LLC 3.01% of their portfolio | 447.9k $16.1m | Added +47.2k |
| Penn Capital Management Company, LLC 1.38% of their portfolio | 443.4k $16.0m | Added +51.2k |
| VOYA INVESTMENT MANAGEMENT LLC 0.02% of their portfolio | 422.8k $15.2m | Reduced -178.1k |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.03% of their portfolio | 422.1k $5.2m | Added +390.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 409.4k $14.7m | Added +122.3k |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 404.7k $14.6m | Added +22.8k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 396.1k $14.3m | Reduced -29.9k |
| DIADEMA PARTNERS LP 8.31% of their portfolio | 371.4k $13.4m | Added +163.6k |
| Legal & General Group Plc 0.00% of their portfolio | 366.1k $13.2m | Reduced -15.0k |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 348.5k $12.5m | Added +196.3k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.02% of their portfolio | 332.8k $12.0m | Added +39.6k |
| Jump Financial, LLC 0.14% of their portfolio | 320.0k $11.5m | Added +270.9k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 316.6k $11.4m | Added +23.0k |
| Ensign Peak Advisors, Inc 0.02% of their portfolio | 308.1k $11.1m | Reduced -20.9k |
| Swiss National Bank 0.01% of their portfolio | 285.2k $10.3m | Reduced -1.3k |
| Marex Group Ltd 0.19% of their portfolio | 278.3k $10.0m | Added +3.3k |
| CASTLEARK MANAGEMENT LLC 0.27% of their portfolio | 250.4k $9.0m | Added +13.3k |
| Cubist Systematic Strategies, LLC 0.10% of their portfolio | 244.0k $8.8m | New |
| Ikarian Capital, LLC 2.50% of their portfolio | 209.9k $7.6m | Reduced -127 |
| FIRST TRUST ADVISORS LP 0.01% of their portfolio | 197.4k $7.1m | Reduced -25.4k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% of their portfolio | 192.3k $6.9m | Reduced -6.7k |
| IFP Advisors, Inc 0.20% of their portfolio | 190.7k $6.9m | Added +2.6k |
| PRUDENTIAL FINANCIAL INC 0.01% of their portfolio | 189.3k $6.8m | Added +9.9k |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 188.2k $6.8m | Added +6.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 177.1k $6.4m | Added +7.7k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.01% of their portfolio | 172.3k $6.2m | Reduced -3.5k |
| LPL Financial LLC 0.00% of their portfolio | 165.1k $5.9m | Reduced -20.0k |
| M28 Capital Management LP 9.92% of their portfolio | 161.6k $5.8m | Unchanged |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 156.3k $5.6m | Reduced -23.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 149.5k $5.4m | Added +14.0k |
| Nicholas Investment Partners, LP 0.47% of their portfolio | 146.9k $5.3m | Added +37.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 146.0k $5.3m | Reduced -442.0k |
| 1832 Asset Management L.P. 0.01% of their portfolio | 144.0k $5.2m | Reduced -1.3m |
| Man Group plc 0.01% of their portfolio | 139.8k $5.0m | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 136.9k $4.9m | Reduced -11.8k |
| HUSSMAN STRATEGIC ADVISORS, INC. 1.04% of their portfolio | 126.0k $4.5m | Added +73.5k |
| FEDERATED HERMES, INC. 0.01% of their portfolio | 125.0k $4.5m | Added +58.7k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 123.5k $4.4m | Reduced -8.9k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 120.9k $4.3m | Added +500 |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 118.1k $4.3m | Added +56.2k |
| CANADA LIFE ASSURANCE Co 0.01% of their portfolio | 116.9k $4.2m | Reduced -423 |
| Rhenman & Partners Asset Management AB 0.52% of their portfolio | 115.0k $4.1m | Reduced -62.5k |
| OSAIC HOLDINGS, INC. 0.01% of their portfolio | 113.3k $4.1m | Reduced -39.4k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 106.0k $3.8m | Added +13.9k |
| MIRAE ASSET SECURITIES (USA) INC. 0.16% of their portfolio | 100.3k $3.6m | Reduced -80.5k |
| Quantum Private Wealth, LLC 1.17% of their portfolio | 100.0k $3.6m | Unchanged |
| TANG CAPITAL MANAGEMENT LLC 0.18% of their portfolio | 100.0k $3.6m | Unchanged |
| Thrivent Financial for Lutherans 0.01% of their portfolio | 99.7k $3.6m | Added +1.7k |
| Hennion & Walsh Asset Management, Inc. 0.14% of their portfolio | 93.8k $3.4m | Reduced -1.4k |
| NJ State Employees Deferred Compensation Plan 0.39% of their portfolio | 91.6k $3.3m | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 91.4k $3.3m | Added +18.5k |
| NORGES BANK 0.00% of their portfolio | 89.8k $3.2m | Reduced -128.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% of their portfolio | 88.8k $3.2m | Reduced -2.8k |
| FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio | 88.2k $2.8m | New |
| MetLife Investment Management, LLC 0.02% of their portfolio | 86.5k $3.1m | Added +5.3k |
| Point72 Europe (London) LLP 0.16% of their portfolio | 85.9k $3.1m | New |
| Persistent Asset Partners Ltd 2.70% of their portfolio | 85.6k $3.1m | Added +49.5k |
| SECTOR GAMMA AS 0.96% of their portfolio | 82.0k $3.0m | Added +27.0k |
| State of Alaska, Department of Revenue 0.03% of their portfolio | 80.8k $2.9m | Added +6.8k |