Vault-13

TAKEDA PHARMACEUTICAL CO LTD TAK

SPONSORED ADS · ADR · CUSIP 874060205 · ISIN US8740602052

Japanese pharmaceutical company

349 institutional holders +18 vs Q3 2025
83,626,36883.6m shares reported held*
$1.3bnreported value*
50 new 97 added 127 reduced 43 sold out net sold ≈ $28.2m (-1.8m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($3.3m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $15.60. Options: 6 managers hold calls ($32.6m notional), 2 hold puts ($2.5m).

Trends to Q4 2025

Institutional holders

Managers reporting a position, each quarter

0200400Q3 22: 276Q4 22: 281Q1 23: 301Q2 23: 312Q3 23: 314Q4 23: 307Q1 24: 312Q2 24: 285Q3 24: 300Q4 24: 303Q1 25: 311Q2 25: 318Q3 25: 331Q4 25: 349349Q3 22Q2 23Q1 24Q4 24Q4 25
Numbers
QuarterHolders
Q3 2022276
Q4 2022281
Q1 2023301
Q2 2023312
Q3 2023314
Q4 2023307
Q1 2024312
Q2 2024285
Q3 2024300
Q4 2024303
Q1 2025311
Q2 2025318
Q3 2025331
Q4 2025349

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q1 24: 155 bought or addedQ1 24: 116 cut or sold outQ2 24: 116 bought or addedQ2 24: 157 cut or sold outQ2 24Q3 24: 160 bought or addedQ3 24: 112 cut or sold outQ4 24: 136 bought or addedQ4 24: 137 cut or sold outQ4 24Q1 25: 163 bought or addedQ1 25: 129 cut or sold outQ2 25: 173 bought or addedQ2 25: 101 cut or sold outQ2 25Q3 25: 186 bought or addedQ3 25: 119 cut or sold outQ4 25: 147 bought or addedQ4 25: 170 cut or sold outQ4 25
Numbers
QuarterBought or addedCut or sold out
Q1 2024155116
Q2 2024116157
Q3 2024160112
Q4 2024136137
Q1 2025163129
Q2 2025173101
Q3 2025186119
Q4 2025147170

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$10m$20m$30m$40mQ1 25 calls: $25.9mQ1 25 puts: $646.5kQ1 25P/C 0.02Q2 25 calls: $26.6mQ2 25 puts: $215.9kQ2 25P/C 0.01Q3 25 calls: $25.3mQ3 25 puts: $1.9mQ3 25P/C 0.08Q4 25 calls: $32.6mQ4 25 puts: $2.5mQ4 25P/C 0.08
Numbers
QuarterCallsPutsP/C
Q1 2025$25.9m$646.5k0.02
Q2 2025$26.6m$215.9k0.01
Q3 2025$25.3m$1.9m0.08
Q4 2025$32.6m$2.5m0.08

Biggest buyers

D. E. Shaw & Co., Inc. Added +4,012,456+4.0m
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP Added +2,854,069+2.9m
VAN ECK ASSOCIATES CORP Added +1,143,117+1.1m
VOLORIDGE INVESTMENT MANAGEMENT, LLC Added +880,289+880.3k
Focus Partners Wealth Added +461,458+461.5k
CITADEL ADVISORS LLC Added +314,110+314.1k
Vestmark Advisory Solutions, Inc. New +189,574+189.6k
BNP PARIBAS FINANCIAL MARKETS Added +174,355+174.4k
ENVESTNET ASSET MANAGEMENT INC Added +154,030+154.0k
Balyasny Asset Management L.P. New +141,024+141.0k

Biggest sellers

TORONTO DOMINION BANK Reduced -2,181,100-2.2m
UBS Group AG Reduced -1,770,446-1.8m
MILLENNIUM MANAGEMENT LLC Reduced -1,666,117-1.7m
Qube Research & Technologies Ltd Reduced -1,578,338-1.6m
MORGAN STANLEY Reduced -1,317,213-1.3m
RENAISSANCE TECHNOLOGIES LLC Reduced -1,246,300-1.2m
BlackRock, Inc. Reduced -575,991-576.0k
ABC ARBITRAGE SA Sold out -571,863-571.9k
JPMORGAN CHASE & CO Reduced -252,879-252.9k
NATIXIS ADVISORS, LLC Reduced -252,618-252.6k

Biggest calls

CITADEL ADVISORS LLC Reduced $24.6m1.6m shares
MILLENNIUM MANAGEMENT LLC Added $5.9m376.2k shares
Walleye Trading LLC New $1.6m99.6k shares
IMC-Chicago, LLC New $374.2k24.0k shares
GROUP ONE TRADING LLC Reduced $177.7k11.4k shares
BARCLAYS PLC New $81.1k5.2k shares

Biggest puts

MILLENNIUM MANAGEMENT LLC Unchanged $1.5m97.8k shares
Walleye Trading LLC Added $1.0m65.1k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Insider purchases and sales in Q4 2025

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

None reported in Q4 2025.

Holders, Q4 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Capital Research Global Investors 0.04% of their portfolio Los Angeles, CA 13,486,77213.5m $210.3m $210.3m 0.04% Added +82.6k +82,643
2 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 6,373,2026.4m $99.4m $99.4m 0.01% Reduced -1.3m -1,317,213
3 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.05% of their portfolio BOSTON, MA 5,682,8475.7m $88.6m $88.6m 0.05% Added +2.9m +2,854,069
4 GOLDMAN SACHS GROUP INC 0.01% of their portfolio NEW YORK, NY 4,805,2354.8m $74.9m $74.9m 0.01% Reduced -148.1k -148,096
5 D. E. Shaw & Co., Inc. 0.05% of their portfolio New York, NY 4,293,7504.3m $66.9m $66.9m 0.05% Added +4.0m +4,012,456
6 UBS Group AG 0.01% of their portfolio ZURICH, V8 4,123,5234.1m $64.3m $64.3m 0.01% Reduced -1.8m -1,770,446
7 FMR LLC 0.00% of their portfolio BOSTON, MA 4,056,8684.1m $63.2m $63.2m 0.00% Reduced -130.1k -130,078
8 BRANDES INVESTMENT PARTNERS, LP 0.46% of their portfolio LA JOLLA, CA 3,881,8823.9m $60.5m $60.5m 0.46% Reduced -49.9k -49,921
9 BlackRock, Inc. 0.00% of their portfolio New York, NY 2,731,5982.7m $42.6m $42.6m 0.00% Reduced -576.0k -575,991
10 RENAISSANCE TECHNOLOGIES LLC 0.06% of their portfolio NEW YORK, NY 2,618,3002.6m $40.8m $40.8m 0.06% Reduced -1.2m -1,246,300
11 FIRST TRUST ADVISORS LP 0.03% of their portfolio Wheaton, IL 2,382,6292.4m $37.1m $37.1m 0.03% Reduced -134.8k -134,810
12 VAN ECK ASSOCIATES CORP 0.03% of their portfolio NEW YORK, NY 2,305,3972.3m $35.9m $35.9m 0.03% Added +1.1m +1,143,117
13 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 1,698,9151.7m $26.5m $26.5m 0.00% Reduced -124.8k -124,795
14 MANAGED ASSET PORTFOLIOS, LLC 2.82% of their portfolio ROCHESTER, MI 1,495,7461.5m $23.3m $23.3m 2.82% Added +9.3k +9,338
15 Quantinno Capital Management LP 0.03% of their portfolio NEW YORK, NY 1,069,3271.1m $16.7m $16.7m 0.03% Added +95.5k +95,472
16 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 1,060,4611.1m $16.5m $16.5m 0.00% Added +26.2k +26,199
17 ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio Berwyn, PA 1,020,6441.0m $15.9m $15.9m 0.00% Added +154.0k +154,030
18 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio JUPITER, FL 962,502962.5k $15.0m $15.0m 0.05% Added +880.3k +880,289
19 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 890,089890.1k $13.9m $13.9m 0.01% Reduced -1.7m -1,666,117
20 TORONTO DOMINION BANK 0.02% of their portfolio TORONTO, ONTARIO, A6 823,200823.2k $12.8m $12.8m 0.02% Reduced -2.2m -2,181,100
21 Crossmark Global Holdings, Inc. 0.17% of their portfolio HOUSTON, TX 745,176745.2k $11.6m $11.6m 0.17% Added +17.9k +17,942
22 AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio Greenwich, CT 679,277679.3k $10.6m $10.6m 0.01% Reduced -87.0k -87,007
23 Focus Partners Wealth 0.01% of their portfolio ST LOUIS, MO 562,049562.0k $8.8m $8.8m 0.01% Added +461.5k +461,458
24 STIFEL FINANCIAL CORP 0.01% of their portfolio ST. LOUIS, MO 554,290554.3k $8.6m $8.6m 0.01% Added +45.4k +45,366
25 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 554,126554.1k $8.6m $8.6m 0.00% Added +64.7k +64,732
26 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 413,692413.7k $6.4m $6.4m 0.00% Added +27.9k +27,932
27 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 408,600408.6k $6.4m $6.4m 0.00% Added +9.6k +9,627
28 Creative Planning 0.00% of their portfolio OVERLAND PARK, KS 395,390395.4k $6.2m $6.2m 0.00% Reduced -68.0k -68,004
29 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 389,734389.7k $6.1m $6.1m 0.00% Added +314.1k +314,110
30 FEDERATED HERMES, INC. 0.01% of their portfolio PITTSBURGH, PA 376,863376.9k $5.9m $5.9m 0.01% Reduced -21.5k -21,523
31 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 362,868362.9k $5.7m $5.7m 0.00% Reduced -5.5k -5,482
32 Bleakley Financial Group, LLC 0.10% of their portfolio PARSIPPANY, NJ 362,758362.8k $5.7m $5.7m 0.10% Added +449 +449
33 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 356,434356.4k $5.6m $5.6m 0.00% Added +104.3k +104,259
34 Ethic Inc. 0.07% of their portfolio NEW YORK, NY 304,655304.7k $4.7m $4.7m 0.07% Reduced -6.1k -6,096
35 TWO SIGMA ADVISERS, LP 0.01% of their portfolio NEW YORK, NY 298,400298.4k $4.7m $4.7m 0.01% Added +91.2k +91,200
36 QRG CAPITAL MANAGEMENT, INC. 0.05% of their portfolio BERWYN, PA 288,730288.7k $4.5m $4.5m 0.05% Added +7.6k +7,587
37 Clean Yield Group 1.13% of their portfolio NORWICH, VT 260,804260.8k $4.1m $4.1m 1.13% Reduced -5.2k -5,234
38 HANTZ FINANCIAL SERVICES, INC. 0.06% of their portfolio SOUTHFIELD, MI 253,478253.5k $4.0m $4.0m 0.06% Reduced -6.7k -6,696
39 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 242,179242.2k $3.8m $3.8m 0.00% Reduced -252.9k -252,879
40 NATIXIS ADVISORS, LLC 0.01% of their portfolio Boston, MA 227,754227.8k $3.6m $3.6m 0.01% Reduced -252.6k -252,618
41 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 217,528217.5k $3.4m $3.4m 0.00% Added +98.8k +98,804
42 Pathstone Holdings, LLC 0.01% of their portfolio ENGLEWOOD, NJ 216,377216.4k $3.4m $3.4m 0.01% Reduced -22.0k -21,961
43 MANNING & NAPIER ADVISORS LLC 0.04% of their portfolio Fairport, NY 215,727215.7k $3.4m $3.4m 0.04% Reduced -10.7k -10,711
44 Cetera Investment Advisers 0.00% of their portfolio SCHAUMBURG, IL 208,922208.9k $3.3m $3.3m 0.00% Reduced -4.3k -4,293
45 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 197,507197.5k $3.1m $3.1m 0.00% Reduced -1.6m -1,578,338
46 Catalyst Capital Advisors LLC 0.06% of their portfolio San Juan, PR 192,000192.0k $3.0m $3.0m 0.06% Added +7.0k +7,000
47 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 191,203191.2k $3.0m $3.0m 0.00% Reduced -2.1k -2,096
48 Vestmark Advisory Solutions, Inc. 0.04% of their portfolio Wakefield, MA 189,574189.6k $3.0m $3.0m 0.04% New
49 Mariner, LLC 0.00% of their portfolio Overland Park, KS 187,640187.6k $2.9m $2.9m 0.00% Reduced -61.3k -61,331
50 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 185,549185.5k $2.9m $2.9m 0.00% Added +174.4k +174,355
51 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 180,135180.1k $2.8m $2.8m 0.00% Reduced -1.2k -1,196
52 MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio DENVER, CO 175,738175.7k $2.7m $2.7m 0.00% Reduced -36.9k -36,858
53 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 173,609173.6k $2.7m $2.7m 0.00% Added +19.5k +19,451
54 Corient Private Wealth LP 0.00% of their portfolio MIAMI, FL 167,846167.8k $2.6m $2.6m 0.00% Added +55.7k +55,749
55 Legacy Wealth Asset Management, LLC 0.64% of their portfolio WOODBURY, MN 166,783166.8k $2.6m $2.6m 0.64% Added +301 +301
56 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 163,286163.3k $2.5m $2.5m 0.00% Reduced -5.3k -5,270
57 Carrera Capital Advisors 0.42% of their portfolio TROY, MI 160,359160.4k $2.5m $2.5m 0.42% Added +9.8k +9,761
58 Aquatic Capital Management LLC 0.07% of their portfolio CHICAGO, IL 160,141160.1k $2.5m $2.5m 0.07% Added +114.2k +114,182
59 ASSETMARK, INC 0.00% of their portfolio CONCORD, CA 156,120156.1k $2.4m $2.4m 0.00% Added +33.9k +33,902
60 Callan Family Office, LLC 0.05% of their portfolio RADNOR, PA 154,254154.3k $2.4m $2.4m 0.05% Added +112.9k +112,936
61 Balyasny Asset Management L.P. 0.00% of their portfolio Chicago, IL 141,024141.0k $2.2m $2.2m 0.00% New
62 O'SHAUGHNESSY ASSET MANAGEMENT, LLC 0.01% of their portfolio Stamford, CT 137,256137.3k $2.1m $2.1m 0.01% Reduced -34.0k -33,980
63 Vanguard Personalized Indexing Management, LLC 0.02% of their portfolio OAKLAND, CA 135,397135.4k $2.1m $2.1m 0.02% Reduced -39.7k -39,700
64 BANK OF MONTREAL /CAN/ 0.00% of their portfolio TORONTO, A6 125,642125.6k $2.0m $2.0m 0.00% Added +16.0k +15,962
65 Cerity Partners LLC 0.00% of their portfolio NEW YORK, NY 121,660121.7k $1.9m $1.9m 0.00% Reduced -33.8k -33,829
66 CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio RALEIGH, NC 118,774118.8k $1.9m $1.9m 0.00% Added +77.7k +77,670
67 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 117,636117.6k $1.8m $1.8m 0.00% Added +57.5k +57,456
68 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 115,250115.2k $1.8m $1.8m 0.01% New
69 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 111,154111.2k $1.7m $1.7m 0.00% Reduced -18.5k -18,515
70 Gold Investment Management Ltd. 0.54% of their portfolio EDMONTON, A0 108,282108.3k $1.7m $1.7m 0.54% Added +4.4k +4,407
71 Legal & General Group Plc 0.00% of their portfolio London, X0 107,846107.8k $1.7m $1.7m 0.00% Reduced -15.0k -15,000
72 Summit Global Investments 0.10% of their portfolio BOUNTIFUL, UT 104,373104.4k $1.6m $1.6m 0.10% Added +19.2k +19,171
73 Forum Financial Management, LP 0.02% of their portfolio LOMBARD, IL 102,334102.3k $1.6m $1.6m 0.02% Unchanged
74 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 101,870101.9k $1.6m $1.6m 0.00% Unchanged
75 MML INVESTORS SERVICES, LLC 0.00% of their portfolio SPRINGFIELD, MA 101,844101.8k $1.6m $1.6m 0.00% Added +12.2k +12,216
76 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 99,982100.0k $1.6m $1.6m 0.00% Added +4.7k +4,716
77 HERITAGE INVESTORS MANAGEMENT CORP 0.04% of their portfolio BETHESDA, MD 98,87298.9k $1.5m $1.5m 0.04% Reduced -1.0k -1,000
78 Vise Technologies, Inc. 0.03% of their portfolio NEW YORK, NY 96,31796.3k $1.5m $1.5m 0.03% Added +16.8k +16,817
79 HighTower Advisors, LLC 0.00% of their portfolio CHICAGO, IL 94,82894.8k $1.5m $1.5m 0.00% Reduced -4.0k -4,014
80 Boston Partners 0.00% of their portfolio BOSTON, MA 93,71093.7k $1.5m $1.5m 0.00% Reduced -24.2k -24,244
81 IEQ CAPITAL, LLC 0.00% of their portfolio Foster City, CA 91,11091.1k $1.4m $1.4m 0.00% Added +2.7k +2,740
82 Brooklyn Investment Group 0.06% of their portfolio NEW YORK, NY 86,20586.2k $1.4m $1.4m 0.06% Added +59.1k +59,054
83 Sequoia Financial Advisors, LLC 0.01% of their portfolio Akron, OH 83,23283.2k $1.3m $1.3m 0.01% Reduced -20.6k -20,632
84 Walleye Capital LLC 0.01% of their portfolio NEW YORK, NY 83,08383.1k $1.3m $1.3m 0.01% Reduced -138.4k -138,439
85 QUADRANT CAPITAL GROUP LLC 0.04% of their portfolio CINCINNATI, OH 81,01881.0k $1.3m $1.3m 0.04% Added +33.2k +33,235
86 Orion Porfolio Solutions, LLC 0.01% of their portfolio OMAHA, NE 78,79578.8k $1.2m $1.2m 0.01% Added +7.0k +6,960
87 PCM Encore, LLC 0.25% of their portfolio Aspen, CO 75,79075.8k $1.2m $1.2m 0.25% First filing
88 XTX Topco Ltd 0.03% of their portfolio LONDON, X0 71,47671.5k $1.1m $1.1m 0.03% Added +58.2k +58,183
89 SIGNATUREFD, LLC 0.02% of their portfolio ATLANTA, GA 65,69465.7k $1.0m $1.0m 0.02% Reduced -15.1k -15,089
90 TRUIST FINANCIAL CORP 0.00% of their portfolio CHARLOTTE, NC 65,14465.1k $1.0m $1.0m 0.00% Added +3.7k +3,719
91 China Universal Asset Management Co., Ltd. 0.08% of their portfolio SHANGHAI, F4 64,00064.0k $997.8k $997.8k 0.08% New
92 WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio PLYMOUTH, MN 63,97764.0k $1.0m $1.0m 0.00% Reduced -3.2k -3,167
93 NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio NEW YORK, NY 62,72862.7k $977.9k $977.9k 0.00% Added +14.3k +14,274
94 M&T Bank Corp 0.00% of their portfolio BUFFALO, NY 61,56261.6k $959.8k $959.8k 0.00% Reduced -7.0k -6,953
95 Arjuna Capital 0.23% of their portfolio MANCHESTER, MA 60,99761.0k $950.9k $950.9k 0.23% Added +1.2k +1,191
96 Tidal Investments LLC 0.00% of their portfolio Milwaukee, WI 60,61460.6k $945.0k $945.0k 0.00% Reduced -31.0k -31,032
97 Vident Advisory, LLC 0.01% of their portfolio Alpharetta, GA 59,13559.1k $921.9k $921.9k 0.01% Reduced -25.6k -25,611
98 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 59,08159.1k $921.0k $921.0k 0.00% Added +13.3k +13,349
99 PNC Financial Services Group, Inc. 0.00% of their portfolio Pittsburgh, PA 58,88258.9k $918.0k $918.0k 0.00% Reduced -14.7k -14,668
100 OPPENHEIMER ASSET MANAGEMENT INC. 0.01% of their portfolio NEW YORK, NY 58,27458.3k $908.5k $908.5k 0.01% Added +294 +294