Vault-13

SKYE BIOSCIENCE INC

COM NEW · CUSIP 83086J200

43 institutional holders +4 vs Q1 2026
16,023,20316.0m shares reported held*
$11.1mreported value*
7 new 2 added 12 reduced 3 sold out net sold ≈ $74.1k (-106.8k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.69. Options: 3 managers hold calls ($78.8k notional), 2 hold puts ($27.3k).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

050100Q4 23: 1Q1 24: 3Q2 24: 63Q3 24: 75Q4 24: 74Q1 25: 76Q2 25: 59Q3 25: 58Q4 25: 50Q1 26: 39Q2 26: 4343Q4 23Q2 24Q4 24Q2 25Q4 25Q2 26
Numbers
QuarterHolders
Q4 20231
Q1 20243
Q2 202463
Q3 202475
Q4 202474
Q1 202576
Q2 202559
Q3 202558
Q4 202550
Q1 202639
Q2 202643

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
50050Q3 24: 39 bought or addedQ3 24: 17 cut or sold outQ4 24: 39 bought or addedQ4 24: 24 cut or sold outQ4 24Q1 25: 29 bought or addedQ1 25: 27 cut or sold outQ2 25: 25 bought or addedQ2 25: 45 cut or sold outQ2 25Q3 25: 21 bought or addedQ3 25: 34 cut or sold outQ4 25: 20 bought or addedQ4 25: 33 cut or sold outQ4 25Q1 26: 10 bought or addedQ1 26: 23 cut or sold outQ2 26: 9 bought or addedQ2 26: 15 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 20243917
Q4 20243924
Q1 20252927
Q2 20252545
Q3 20252134
Q4 20252033
Q1 20261023
Q2 2026915

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$1m$2m$3mQ3 25 calls: $2.3mQ3 25 puts: $118.6kQ3 25P/C 0.05Q4 25 calls: $55.3kQ4 25 puts: $15.8kQ4 25P/C 0.29Q1 26 calls: $25.4kQ1 26 puts: $39.3kQ1 26P/C 1.54Q2 26 calls: $78.8kQ2 26 puts: $27.3kQ2 26P/C 0.35
Numbers
QuarterCallsPutsP/C
Q3 2025$2.3m$118.6k0.05
Q4 2025$55.3k$15.8k0.29
Q1 2026$25.4k$39.3k1.54
Q2 2026$78.8k$27.3k0.35

Biggest buyers

Qube Research & Technologies Ltd New +43,082+43.1k
NORTHERN TRUST CORP Added +36,185+36.2k
UBS Group AG Added +28,038+28.0k
SIMPLEX TRADING, LLC New +26,976+27.0k
JONES FINANCIAL COMPANIES LLLP New +8+8
GILPIN WEALTH MANAGEMENT, LLC New +4+4
Integrated Wealth Concepts LLC New +2+2
FMR LLC New +1+1
WELLS FARGO & COMPANY/MN New +1+1

Biggest sellers

MILLENNIUM MANAGEMENT LLC Reduced -59,676-59.7k
GEODE CAPITAL MANAGEMENT, LLC Reduced -59,201-59.2k
BlackRock, Inc. Reduced -53,257-53.3k
TWO SIGMA INVESTMENTS, LP Sold out -25,684-25.7k
XTX Topco Ltd Reduced -19,926-19.9k
BARCLAYS PLC Reduced -17,434-17.4k
GROUP ONE TRADING LLC Reduced -2,616-2.6k
STATE STREET CORP Reduced -1,496-1.5k
FEDERATED HERMES, INC. Sold out -1,158-1.2k
VANGUARD CAPITAL MANAGEMENT LLC Reduced -575-575

Biggest calls

CITADEL ADVISORS LLC Added $61.4k88.6k shares
GROUP ONE TRADING LLC New $15.9k23.0k shares
SIMPLEX TRADING, LLC Reduced $1.5k2.1k shares

Biggest puts

CITADEL ADVISORS LLC Reduced $24.5k35.4k shares
GROUP ONE TRADING LLC Unchanged $2.8k4.0k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
5AM Partners VII, LLC 13D · may seek influence -3.8 pts · filed 2026-08-18
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: Transaction with Redx Pharma Limited On August 14, 2026, the Issuer entered into a transaction agreement ("Transaction Agreement") with Redx Pharma Limited, a private limited company incorporated in England and Wales with registered number 07368089 ("Redx"). The Transaction Agreement provides that, subject to the terms and conditions set forth therein, including the requisite approval of each of the Issuer's and Redx's shareholders, the Issuer will acquire the entire issued and to be issued share capital of Redx pursuant to a scheme of arrangement under Part 26 of the United Kingdom Companies Act 2006 (the "Scheme of Arrangement" and such transaction, the "Transaction"). Under the Transaction Agreement, following th… Full filing
 30.2% -3.8 pts 11.3m≈ $7.8m 2026-08-18

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 5AM Venture Management, LLC 2.33% of their portfolio SAN FRANCISCO, CA 9,681,7639.7m $6.7m $6.7m 2.33% Unchanged
2 Versant Venture Management, LLC 0.86% of their portfolio San Francisco, CA 2,007,7042.0m $1.4m $1.4m 0.86% Unchanged
3 BAKER BROS. ADVISORS LP 0.01% of their portfolio NEW YORK, NY 1,575,2431.6m $1.1m $1.1m 0.01% Unchanged
4 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 763,882763.9k $529.4k $529.4k 0.00% Reduced -575 -575
5 SPHERA FUNDS MANAGEMENT LTD. 0.07% of their portfolio TEL AVIV, L3 678,928678.9k $470.7k $470.7k 0.07% Unchanged
6 PLATINUM INVESTMENT MANAGEMENT LTD 0.04% of their portfolio SYDNEY AUSTRALIA 2000, C3 233,095233.1k $161.6k $161.6k 0.04% Unchanged
7 BlackRock, Inc. 0.00% of their portfolio New York, NY 232,874232.9k $161.5k $161.5k 0.00% Reduced -53.3k -53,257
8 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 218,055218.1k $151.2k $151.2k 0.00% Reduced -59.2k -59,201
9 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 198,524198.5k $137.6k $137.6k 0.00% Reduced -59.7k -59,676
10 VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio MALVERN, PA 104,229104.2k $72.2k $72.2k 0.00% Unchanged
11 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 73,83073.8k $51.2k $51.2k 0.00% Reduced -1.5k -1,496
12 UBS Group AG 0.00% of their portfolio ZURICH, V8 73,80073.8k $51.1k $51.1k 0.00% Added +28.0k +28,038
13 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 56,32756.3k $39.1k $39.1k 0.00% Added +36.2k +36,185
14 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 43,08243.1k $29.9k $29.9k 0.00% New
15 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 26,97627.0k $18.7k $18.7k 0.00% New
16 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 20,99321.0k $14.6k $14.6k 0.00% Reduced -19.9k -19,926
17 Engineers Gate Manager LP 0.00% of their portfolio NEW YORK, NY 20,19420.2k $14.0k $14.0k 0.00% Unchanged
18 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 4,5894.6k $3.2k $3.2k 0.00% Reduced -2.6k -2,616
19 Vanguard Global Advisers, LLC 0.00% of their portfolio MALVERN, PA 4,5574.6k $3.2k $3.2k 0.00% Unchanged
20 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 2,4692.5k $1.7k $1.7k 0.00% Reduced -80 -80
21 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 655655 $455 $455 0.00% Reduced -17.4k -17,434
22 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 600600 $413 $413 0.00% Unchanged
23 NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio MONTREAL, A8 400400 $275 $275 0.00% Unchanged
24 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 120120 $0 $0 0.00% Reduced -7 -7
25 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 6666 $44 $44 0.00% Unchanged
26 Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio ZURICH, V8 5252 $36 $36 0.00% Unchanged
27 TD Waterhouse Canada Inc. 0.00% of their portfolio TORONTO, A6 5252 $35 $35 0.00% Reduced -27 -27
28 Federation des caisses Desjardins du Quebec 0.00% of their portfolio LEVIS, A8 5151 $35 $35 0.00% Unchanged
29 Rockefeller Capital Management L.P. 0.00% of their portfolio NEW YORK, NY 3939 $27 $27 0.00% Unchanged
30 Optiver Holding B.V. 0.00% of their portfolio AMSTERDAM, P7 2020 $14 $14 0.00% Unchanged
31 JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio DES PERES, MO 88 $5 $5 0.00% New
32 CoreCap Advisors, LLC 0.00% of their portfolio SOUTHFIELD, MI 88 $6 $6 0.00% Unchanged
33 GILPIN WEALTH MANAGEMENT, LLC 0.00% of their portfolio DENVER, CO 44 $3 $3 0.00% New
34 Plante Moran Financial Advisors, LLC 0.00% of their portfolio SOUTHFIELD, MI 33 $2 $2 0.00% Unchanged
35 Integrated Wealth Concepts LLC 0.00% of their portfolio WALTHAM, MA 22 $2 $2 0.00% New
36 MCGUIRE CAPITAL ADVISORS INC 0.00% of their portfolio BETHANY, OK 22 $1 $1 0.00% Unchanged
37 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 11 $1 $1 0.00% New
38 FMR LLC 0.00% of their portfolio BOSTON, MA 11 $1 $1 0.00% New
39 HARBOUR INVESTMENTS, INC. 0.00% of their portfolio MADISON, WI 11 $1 $1 0.00% Unchanged
40 IFP Advisors, Inc 0.00% of their portfolio TAMPA, FL 11 $1 $1 0.00% Reduced -1 -1
41 NFSG Corp 0.00% of their portfolio BOCA RATON, FL 11 $1 $1 0.00% Unchanged
42 Leo H. Evart, Inc. 0.00% of their portfolio REDWOOD CITY, CA 11 $1 $1 0.00% Unchanged
43 PFS Partners, LLC 0.00% of their portfolio MINE HILL, NJ 11 $1 $1 0.00% Unchanged