ARS PHARMACEUTICALS INC SPRY
COM · Common Stock · CUSIP 82835W108
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- Founded2016
- Websitesilverbacktx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($167.7k this quarter). Holder counts are more reliable. Shares outstanding: 97.2m as of 2024-11-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $10.55. Options: 11 managers hold calls ($2.7m notional), 6 hold puts ($3.6m).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 61 |
| Q4 2022 | 74 |
| Q1 2023 | 91 |
| Q2 2023 | 94 |
| Q3 2023 | 98 |
| Q4 2023 | 101 |
| Q1 2024 | 114 |
| Q2 2024 | 116 |
| Q3 2024 | 152 |
| Q4 2024 | 167 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 61 | 26 |
| Q2 2023 | 64 | 46 |
| Q3 2023 | 61 | 39 |
| Q4 2023 | 47 | 45 |
| Q1 2024 | 64 | 40 |
| Q2 2024 | 66 | 46 |
| Q3 2024 | 105 | 35 |
| Q4 2024 | 86 | 61 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $6.4m | $1.0m | 0.16 |
| Q2 2024 | $19.2m | $820.7k | 0.04 |
| Q3 2024 | $14.2m | $9.5m | 0.67 |
| Q4 2024 | $2.7m | $3.6m | 1.36 |
Biggest buyers
| ALLIANCEBERNSTEIN L.P. | Added | +3.8m |
| Alyeska Investment Group, L.P. | Added | +1.1m |
| UBS Group AG | Added | +902.8k |
| STATE STREET CORP | Added | +700.4k |
| GOLDMAN SACHS GROUP INC | Added | +610.3k |
| CITADEL ADVISORS LLC | Added | +553.0k |
| Cormorant Asset Management, LP | New | +500.0k |
| MILLENNIUM MANAGEMENT LLC | Added | +452.5k |
| PEREGRINE CAPITAL MANAGEMENT LLC | New | +423.6k |
| BANK OF MONTREAL /CAN/ | New | +340.6k |
Biggest sellers
| FRANKLIN RESOURCES INC | Reduced | -860.8k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Reduced | -563.3k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -551.7k |
| Duquesne Family Office LLC | Sold out | -536.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -442.6k |
| Informed Momentum Co LLC | Sold out | -261.6k |
| MORGAN STANLEY | Reduced | -206.0k |
| Nextech Invest Ltd. | Reduced | -176.3k |
| K2 PRINCIPAL FUND, L.P. | Sold out | -120.0k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -116.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $576.0k54.6k shares |
| WOLVERINE TRADING, LLC | Reduced | $400.4k37.7k shares |
| BANK OF MONTREAL /CAN/ | New | $333.4k31.6k shares |
| J. Goldman & Co LP | Added | $285.9k27.1k shares |
| K2 PRINCIPAL FUND, L.P. | Reduced | $284.9k27.0k shares |
| JANE STREET GROUP, LLC | New | $262.7k24.9k shares |
| GROUP ONE TRADING LLC | Reduced | $232.1k22.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $148.0k14.1k shares |
| CITADEL ADVISORS LLC | Added | $123.4k11.7k shares |
| DIADEMA PARTNERS LP | First filing | $33.8k3.2k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $2.4m230.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $899.9k85.3k shares |
| SIMPLEX TRADING, LLC | Reduced | $147.0k14.0k shares |
| WOLVERINE TRADING, LLC | Reduced | $134.9k12.7k shares |
| GROUP ONE TRADING LLC | Reduced | $33.8k3.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
filed 2025-10-01
Stated purposeItem 4 is hereby amended and supplemented as follows: On September 29, 2025, the Issuer and certain direct and indirect subsidiaries of the Issuer who may become a party thereto from time to time, as guarantors (the "Guarantors"), and ARS Pharmaceuticals Operations, Inc., a wholly owned subsidiary of the Issuer, as the borrower (the "Borrower" and, collectively with the Guarantors, the "Credit Parties"), entered into a credit agreement (the "Credit Agreement") with RA Capital Agency Services, LLC (as the "Administrative Agent" and as the "Collateral Agent"), and affiliates of OMERS Administration Corporation and RA Capital, as lenders, and such other lenders from time to time party thereto (the "Lenders"), providing for up to $250.0 million of term loans from the Lenders to the Borrower (… Full filing |
11.1% |
| Rubric Capital Management LP 13G · institution +1.8 pts · filed 2026-05-15 | 8.1% |
| Flynn James E 13D · may seek influence -1.0 pts · filed 2025-08-01 | 7.8% |
| BlackRock, Inc. 13G · institution +0.3 pts · filed 2026-07-27 | 5.3% |
Fell to 5% or below in the last year: MILLENNIUM MANAGEMENT LLC (2.5%, 2026-07-14)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 1 | $1.3m | $1.3m |
| Q3 2023 | 4 | $34.9m | 1 | $2.1m | $1.5m |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 1 | $13.3m | 2 | $2.8m | $2.8m |
| Q2 2024 | 0 | — | 2 | $4.6m | $4.6m |
| Q3 2024 | 0 | — | 7 | $21.5m | $8.9m |
| Q4 2024 | 0 | — | 7 | $19.0m | $12.0m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-12-17 | Tanimoto Sarina CHIEF MEDICAL OFFICER · By Sarina Tanimoto Charitable Remainder UniTrust Dated January 7, 2020 | Sold plan | $583.5k50.0k shares |
| 2024-12-17 | Lowenthal Richard E PRESIDENT AND CEO, director · By Sarina Tanimoto Charitable Remainder UniTrust Dated January 7, 2020 | Sold plan | $583.5k50.0k shares |
| 2024-12-17 | Tanimoto Sarina CHIEF MEDICAL OFFICER · By Lowenthal-Tanimoto Family Trust U/A DTD 4/3/2006 | Sold plan | $583.5k50.0k shares |
| 2024-12-17 | Lowenthal Richard E PRESIDENT AND CEO, director · By Lowenthal-Tanimoto Family Trust U/A DTD 4/3/2006 | Sold plan | $583.5k50.0k shares |
| 2024-12-13 | Chakma Justin Chief Business Officer | Sold | $328.9k27.3k shares |
| 2024-12-12 | Chakma Justin Chief Business Officer | Sold | $1.4m117.3k shares |
| 2024-12-12 | Dorsey Brian Chief Operating Officer | Sold plan | $307.5k25.0k shares |
| 2024-12-11 | Dorsey Brian Chief Operating Officer | Sold plan | $186.4k15.0k shares |
| 2024-12-10 | Tanimoto Sarina CHIEF MEDICAL OFFICER · By Richard Lowenthal Charitable Remainder UniTrust Dated January 7, 2020 | Sold plan | $658.5k50.0k shares |
| 2024-12-10 | Lowenthal Richard E PRESIDENT AND CEO, director · By Richard E. Lowenthal Charitable Remainder UniTrust Dated January 7, 2020 | Sold plan | $658.5k50.0k shares |
| 2024-12-10 | Tanimoto Sarina CHIEF MEDICAL OFFICER · By Lowenthal-Tanimoto Family Trust U/A DTD 4/3/2006 | Sold plan | $658.0k50.0k shares |
| 2024-12-10 | Lowenthal Richard E PRESIDENT AND CEO, director · By Lowenthal-Tanimoto Family Trust U/A DTD 4/3/2006 | Sold plan | $658.0k50.0k shares |
| 2024-12-10 | Chakma Justin Chief Business Officer | Sold | $657.5k50.0k shares |
| 2024-12-06 | Chakma Justin Chief Business Officer | Sold | $711.5k50.0k shares |
| 2024-12-05 | Chakma Justin Chief Business Officer | Sold | $701.4k49.6k shares |
| 2024-12-04 | Chakma Justin Chief Business Officer | Sold | $627.8k45.0k shares |
| 2024-12-04 | Shawver Laura Director | Sold plan | $203.1k14.8k shares |
| 2024-12-04 | Karas Eric Chief Commercial Officer | Sold plan | $88.0k6.3k shares |
| 2024-12-03 | Shawver Laura Director | Sold plan | $1.2m88.0k shares |
| 2024-12-03 | Chakma Justin Chief Business Officer | Sold | $593.5k45.0k shares |
| 2024-12-02 | Shawver Laura Director | Sold plan | $1.3m97.2k shares |
| 2024-12-02 | Chakma Justin Chief Business Officer | Sold | $615.1k45.0k shares |
| 2024-12-02 | Karas Eric Chief Commercial Officer | Sold plan | $52.4k3.7k shares |
| 2024-11-27 | Chakma Justin Chief Business Officer | Sold | $359.8k25.0k shares |
| 2024-11-26 | Chakma Justin Chief Business Officer | Sold | $592.7k42.2k shares |
| 2024-11-25 | Chakma Justin Chief Business Officer | Sold | $459.4k32.8k shares |
| 2024-11-19 | Tanimoto Sarina CHIEF MEDICAL OFFICER · By Lowenthal-Tanimoto Family Trust U/A DTD 4/3/2006 | Sold plan | $697.5k50.0k shares |
| 2024-11-19 | Tanimoto Sarina CHIEF MEDICAL OFFICER · By Sarina Tanimoto Charitable Remainder UniTrust Dated January 7, 2020 | Sold plan | $697.5k50.0k shares |
| 2024-11-19 | Lowenthal Richard E PRESIDENT AND CEO, director · By Lowenthal-Tanimoto Family Trust U/A DTD 4/3/2006 | Sold plan | $697.5k50.0k shares |
| 2024-11-19 | Lowenthal Richard E PRESIDENT AND CEO, director · By Sarina Tanimoto Charitable Remainder UniTrust Dated January 7, 2020 | Sold plan | $697.5k50.0k shares |
The latest 30 of 48 trades.
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 1.52% of their portfolio | 10.9m $114.6m | Unchanged |
| DEERFIELD MANAGEMENT COMPANY, L.P. 2.11% of their portfolio | 10.5m $110.9m | Reduced -563.3k |
| ORBIMED ADVISORS LLC 1.82% of their portfolio | 8.3m $87.4m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 4.6m $48.3m | Added +328.5k |
| SR One Capital Management, LP 10.32% of their portfolio | 4.0m $42.3m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 3.9m $40.9m | Added +3.8m |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.5m $36.6m | Added +115.7k |
| STATE STREET CORP 0.00% of their portfolio | 2.7m $29.0m | Added +700.4k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 2.0m $20.9m | Reduced -860.8k |
| Alyeska Investment Group, L.P. 0.05% of their portfolio | 1.3m $13.2m | Added +1.1m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.2m $13.1m | Added +3.4k |
| Woodline Partners LP 0.08% of their portfolio | 1.1m $11.8m | Added +133.3k |
| FMR LLC 0.00% of their portfolio | 1.1m $11.6m | Added +15.9k |
| UBS Group AG 0.00% of their portfolio | 1.0m $10.7m | Added +902.8k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 939.3k $9.9m | Added +452.5k |
| Nextech Invest Ltd. 1.60% of their portfolio | 936.7k $9.9m | Reduced -176.3k |
| ROYCE & ASSOCIATES LP 0.09% of their portfolio | 929.6k $9.8m | Added +238.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 886.1k $9.3m | Added +610.3k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 805.5k $8.5m | Added +553.0k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 623.3k $6.6m | First filing |
| First Turn Management, LLC 1.12% of their portfolio | 593.3k $6.3m | Unchanged |
| Cormorant Asset Management, LP 0.29% of their portfolio | 500.0k $5.3m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 478.2k $5.0m | Added +25.8k |
| LEVIN CAPITAL STRATEGIES, L.P. 0.47% of their portfolio | 467.6k $4.9m | Added +198.2k |
| MORGAN STANLEY 0.00% of their portfolio | 432.6k $4.6m | Reduced -206.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 427.5k $4.5m | Added +3.5k |
| PEREGRINE CAPITAL MANAGEMENT LLC 0.13% of their portfolio | 423.6k $4.5m | New |
| WEXFORD CAPITAL LP 1.00% of their portfolio | 369.5k $3.9m | Added +121.2k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 344.9k $3.6m | Added +322.4k |
| Allspring Global Investments Holdings, LLC 0.01% of their portfolio | 344.2k $3.6m | Added +165.9k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 340.6k $3.6m | New |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 286.8k $3.0m | Added +40.9k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 247.3k $2.6m | Added +12.8k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 196.5k $2.1m | Added +4.0k |
| Nicholas Investment Partners, LP 0.16% of their portfolio | 172.0k $1.8m | Reduced -29.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 171.4k $1.8m | Added +24.1k |
| Miura Global Management, LLC 1.96% of their portfolio | 170.0k $1.8m | Reduced -100.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 163.3k $1.7m | Added +917 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 161.0k $1.7m | Added +48.1k |
| BARCLAYS PLC 0.00% of their portfolio | 158.2k $1.7m | Added +46.5k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 158.0k $1.7m | Unchanged |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 140.4k $1.5m | Added +59.1k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 130.3k $1.4m | Added +90.6k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 130.2k $1.4m | Reduced -1.4k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 108.3k $1.1m | New |
| SECTORAL ASSET MANAGEMENT INC 0.75% of their portfolio | 106.0k $1.1m | Added +7.4k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 101.4k $1.1m | Reduced -551.7k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 100.9k $1.1m | Added +74.0k |
| CITIGROUP INC 0.00% of their portfolio | 100.7k $1.1m | Added +63.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 98.1k $1.0m | Reduced -116.0k |
| FAS Wealth Partners, Inc. 0.08% of their portfolio | 94.7k $999.1k | Added +9.8k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 93.0k $981.5k | Reduced -5.4k |
| DAFNA Capital Management LLC 0.24% of their portfolio | 88.8k $936.7k | Reduced -59.5k |
| Cambridge Investment Research Advisors, Inc. 0.00% of their portfolio | 87.2k $920.0k | Unchanged |
| VALLEY FORGE INVESTMENT CONSULTANTS INC ADV 0.30% of their portfolio | 83.2k $878.0k | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 80.6k $850.8k | Added +3.4k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 76.7k $809.5k | Reduced -3.8k |
| Swiss National Bank 0.00% of their portfolio | 75.7k $798.6k | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 69.4k $731.9k | Added +36.9k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 67.3k $709.8k | Added +19.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 65.2k $687.5k | Added +1.8k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 60.3k $636.1k | Added +2.7k |
| Trexquant Investment LP 0.01% of their portfolio | 56.6k $596.7k | Reduced -28.7k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 52.9k $558.2k | Reduced -25.0k |
| SG Americas Securities, LLC 0.00% of their portfolio | 51.2k $540.0k | Reduced -7.1k |
| Panoramic Capital, LLC 0.38% of their portfolio | 45.8k $483.3k | First filing |
| Tower Research Capital LLC (TRC) 0.01% of their portfolio | 45.6k $480.8k | Added +41.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 43.4k $457.6k | Added +14.6k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 41.7k $439.9k | Added +13.4k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 41.0k $432.6k | Reduced -400 |
| Steward Partners Investment Advisory, LLC 0.00% of their portfolio | 38.0k $401.4k | Added +12.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 37.0k $390.2k | Reduced -414 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 36.3k $383.4k | Reduced -5.4k |
| Mariner, LLC 0.00% of their portfolio | 35.9k $378.8k | Added +2.0k |
| Legal & General Group Plc 0.00% of their portfolio | 35.4k $373.6k | Added +1.5k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 33.6k $354.4k | Added +3.3k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 33.1k $349.1k | Added +3.8k |
| XTX Topco Ltd 0.03% of their portfolio | 32.2k $339.9k | Added +15.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 31.1k $328.2k | Reduced -34.5k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 30.5k $322.2k | Added +14.1k |
| Creative Planning 0.00% of their portfolio | 30.2k $318.7k | Reduced -5.1k |
| AssuredPartners Investment Advisors, LLC 0.06% of their portfolio | 29.6k $312.4k | First filing |
| Cresset Asset Management, LLC 0.00% of their portfolio | 27.8k $292.8k | Added +3.3k |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 27.2k $287.0k | Reduced -2.0k |
| HighTower Advisors, LLC 0.00% of their portfolio | 27.1k $286.0k | Reduced -1.2k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 26.9k $283.5k | Added +10.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 24.8k $261.4k | Reduced -9.2k |
| LETKO, BROSSEAU & ASSOCIATES INC 0.01% of their portfolio | 24.7k $260.6k | Unchanged |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 24.6k $260.0k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 24.5k $258.1k | Reduced -1.8k |
| STRS OHIO 0.00% of their portfolio | 24.0k $253.2k | Unchanged |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 21.6k $228.0k | Unchanged |
| Legato Capital Management LLC 0.03% of their portfolio | 21.5k $226.4k | Reduced -2.9k |
| LPL Financial LLC 0.00% of their portfolio | 21.4k $225.9k | Added +2.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 21.2k $223.2k | Reduced -67.6k |
| WOLVERINE TRADING, LLC 0.00% of their portfolio | 20.8k $220.5k | Added +1.0k |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 20.6k $217.4k | Added +2.0k |
| Aigen Investment Management, LP 0.04% of their portfolio | 20.5k $216.4k | New |
| CIBC Private Wealth Group LLC 0.00% of their portfolio | 20.0k $228.6k | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 20.0k $210.9k | Reduced -105.6k |