SCHRODINGER INC SDGR
COM · Common Stock · CUSIP 80810D103 · ISIN US80810D1037
American life sciences company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Founded1990
- Websiteschrodinger.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($52.4m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $20.12. Options: 12 managers hold calls ($55.5m notional), 11 hold puts ($6.0m).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 198 |
| Q4 2022 | 171 |
| Q1 2023 | 184 |
| Q2 2023 | 241 |
| Q3 2023 | 237 |
| Q4 2023 | 240 |
| Q1 2024 | 224 |
| Q2 2024 | 208 |
| Q3 2024 | 209 |
| Q4 2024 | 213 |
| Q1 2025 | 220 |
| Q2 2025 | 234 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 118 | 123 |
| Q4 2023 | 115 | 114 |
| Q1 2024 | 101 | 115 |
| Q2 2024 | 97 | 110 |
| Q3 2024 | 95 | 104 |
| Q4 2024 | 87 | 105 |
| Q1 2025 | 104 | 89 |
| Q2 2025 | 120 | 106 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $14.2m | $7.5m | 0.53 |
| Q4 2024 | $10.3m | $6.9m | 0.68 |
| Q1 2025 | $15.3m | $5.0m | 0.33 |
| Q2 2025 | $55.5m | $6.0m | 0.11 |
Biggest buyers
| CADIAN CAPITAL MANAGEMENT, LP | Added | +1.9m |
| BlackRock, Inc. | Added | +1.3m |
| UBS Group AG | Added | +929.0k |
| ROYAL BANK OF CANADA | Added | +757.7k |
| TWO SIGMA ADVISERS, LP | Added | +596.8k |
| TWO SIGMA INVESTMENTS, LP | Added | +578.7k |
| BANK OF AMERICA CORP /DE/ | Added | +492.0k |
| Stephens Investment Management Group LLC | Added | +291.4k |
| Rubric Capital Management LP | Added | +200.0k |
| Sumitomo Mitsui Trust Group, Inc. | Added | +187.5k |
Biggest sellers
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Reduced | -942.3k |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | Reduced | -732.6k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Reduced | -598.6k |
| Prosight Management, LP | Sold out | -385.0k |
| CITADEL ADVISORS LLC | Reduced | -371.7k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -367.4k |
| ARK Investment Management LLC | Reduced | -335.3k |
| CITIGROUP INC | Reduced | -217.6k |
| LAZARD ASSET MANAGEMENT LLC | Reduced | -199.0k |
| Stanley-Laman Group, Ltd. | Sold out | -187.0k |
Biggest calls
| PEAK6 LLC | Added | $41.5m2.1m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $7.7m383.3k shares |
| Walleye Capital LLC | Added | $1.0m50.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $973.0k48.4k shares |
| IMC-Chicago, LLC | Reduced | $937.6k46.6k shares |
| WOLVERINE TRADING, LLC | Reduced | $929.5k45.1k shares |
| CITADEL ADVISORS LLC | Reduced | $909.4k45.2k shares |
| GROUP ONE TRADING LLC | Added | $497.0k24.7k shares |
| JANE STREET GROUP, LLC | Added | $472.8k23.5k shares |
| Walleye Trading LLC | New | $404.4k20.1k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.4m118.4k shares |
| CITADEL ADVISORS LLC | Reduced | $1.3m62.7k shares |
| PEAK6 LLC | New | $623.7k31.0k shares |
| IMC-Chicago, LLC | Reduced | $460.7k22.9k shares |
| Walleye Capital LLC | New | $416.5k20.7k shares |
| JANE STREET GROUP, LLC | New | $344.1k17.1k shares |
| WOLVERINE TRADING, LLC | New | $335.9k16.3k shares |
| SIMPLEX TRADING, LLC | Reduced | $72.0k3.6k shares |
| Walleye Trading LLC | New | $68.4k3.4k shares |
| GROUP ONE TRADING LLC | Added | $66.4k3.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-07-18 | 12.7% |
| Rubric Capital Management LP 13G · institution +2.8 pts · filed 2026-05-15 | 9.3% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 6.0% |
Fell to 5% or below in the last year: Sumitomo Mitsui Trust Group, Inc. (4.9%, 2026-04-30), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 1 | $400.6k | $400.6k |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 5 | $189.7k | $102.4k |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 1 | $27.2k | $27.2k |
| Q1 2025 | 0 | — | 5 | $339.9k | $220.4k |
| Q2 2025 | 0 | — | 1 | $419.5k | $419.5k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-04-14 | Akinsanya Karen President of R&D, Therapeutics | Sold plan | $419.5k16.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 9.8m $196.7m | Added +1.3m |
| GATES FOUNDATION TRUST 0.29% of their portfolio | 7.0m $140.5m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 6.6m $133.1m | Added +72.8k |
| Rubric Capital Management LP 1.62% of their portfolio | 5.0m $100.6m | Added +200.0k |
| Sumitomo Mitsui Trust Group, Inc. 0.05% of their portfolio | 3.6m $73.4m | Added +187.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 3.4m $68.7m | Reduced -942.3k |
| CADIAN CAPITAL MANAGEMENT, LP 3.43% of their portfolio | 3.0m $61.3m | Added +1.9m |
| Amova Asset Management Americas, Inc. 0.52% of their portfolio | 2.6m $52.1m | Added +174.7k |
| Stephens Investment Management Group LLC 0.60% of their portfolio | 2.3m $45.5m | Added +291.4k |
| STATE STREET CORP 0.00% of their portfolio | 2.2m $44.0m | Reduced -26.2k |
| ARK Investment Management LLC 0.29% of their portfolio | 2.0m $39.4m | Reduced -335.3k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 1.5m $30.1m | Reduced -598.6k |
| LAZARD ASSET MANAGEMENT LLC 0.04% of their portfolio | 1.4m $28.6m | Reduced -199.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.4m $27.4m | Added +18.2k |
| UBS Group AG 0.01% of their portfolio | 1.3m $27.0m | Added +929.0k |
| MORGAN STANLEY 0.00% of their portfolio | 1.2m $23.2m | Reduced -20.6k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.10% of their portfolio | 1.1m $22.3m | Not comparable |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 1.1m $21.9m | Added +84.2k |
| BAILLIE GIFFORD & CO 0.01% of their portfolio | 985.7k $19.8m | Reduced -9.2k |
| TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio | 821.2k $16.5m | Added +578.7k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 792.9k $16.0m | Added +757.7k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 742.5k $14.9m | Reduced -35.6k |
| TWO SIGMA ADVISERS, LP 0.03% of their portfolio | 723.1k $14.5m | Added +596.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 616.0k $12.4m | Added +31.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 606.9k $12.2m | Added +492.0k |
| Parkman Healthcare Partners LLC 1.37% of their portfolio | 587.6k $11.8m | Added +106.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 521.6k $10.5m | Added +10.2k |
| FMR LLC 0.00% of their portfolio | 437.1k $8.8m | Reduced -88.5k |
| TOCQUEVILLE ASSET MANAGEMENT L.P. 0.12% of their portfolio | 391.9k $7.9m | Reduced -732.6k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 355.9k $7.2m | Reduced -45.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 320.4k $6.4m | Reduced -91.0k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 277.2k $5.6m | Added +462 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 266.1k $5.4m | Reduced -371.7k |
| Allspring Global Investments Holdings, LLC 0.01% of their portfolio | 205.3k $4.1m | Added +30.9k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% of their portfolio | 204.0k $4.1m | Unchanged |
| Public Sector Pension Investment Board 0.02% of their portfolio | 190.4k $3.8m | Added +14.7k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 171.3k $3.4m | Added +13.2k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 170.1k $3.4m | Reduced -40.5k |
| Tejara Capital Ltd 1.52% of their portfolio | 162.5k $3.3m | Added +28.3k |
| Legal & General Group Plc 0.00% of their portfolio | 161.7k $3.3m | Added +2.4k |
| Invesco Ltd. 0.00% of their portfolio | 155.9k $3.1m | Added +21.0k |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 150.8k $3.0m | Added +73.3k |
| BARCLAYS PLC 0.00% of their portfolio | 141.8k $2.9m | Added +65.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 140.2k $2.8m | Added +7.3k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 132.0k $2.7m | Reduced -367.4k |
| Nuveen, LLC 0.00% of their portfolio | 130.2k $2.6m | Reduced -15.3k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 126.8k $2.6m | New |
| Integrated Advisors Network LLC 0.11% of their portfolio | 122.6k $2.5m | Added +5.2k |
| Swiss National Bank 0.00% of their portfolio | 122.0k $2.5m | Reduced -1.3k |
| ALGERT GLOBAL LLC 0.05% of their portfolio | 119.4k $2.4m | Added +27.5k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 118.7k $2.4m | Reduced -13.2k |
| Slow Capital, Inc. 0.26% of their portfolio | 103.6k $2.1m | New |
| Geneos Wealth Management Inc. 0.05% of their portfolio | 100.3k $2.0m | Reduced -79.6k |
| Engineers Gate Manager LP 0.02% of their portfolio | 90.9k $1.8m | Added +73.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 83.5k $1.7m | Reduced -22.8k |
| CAPITAL FUND MANAGEMENT S.A. 0.02% of their portfolio | 73.8k $1.5m | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 73.1k $1.5m | Reduced -3.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 72.0k $1.4m | Reduced -6.6k |
| CITIGROUP INC 0.00% of their portfolio | 69.8k $1.4m | Reduced -217.6k |
| Brevan Howard Capital Management LP 0.02% of their portfolio | 67.8k $1.4m | Added +55.8k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 63.8k $1.3m | New |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 63.5k $1.3m | Reduced -5.4k |
| Jump Financial, LLC 0.02% of their portfolio | 61.9k $1.2m | New |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 61.0k $1.2m | New |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 60.8k $1.2m | New |
| Graham Capital Management, L.P. 0.04% of their portfolio | 58.5k $1.2m | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 58.4k $1.2m | Reduced -569 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 58.0k $1.2m | Added +24.9k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 57.7k $1.2m | Added +3.5k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 57.3k $1.2m | New |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 55.7k $1.1m | Reduced -3.8k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 54.1k $1.1m | Added +25.8k |
| LPL Financial LLC 0.00% of their portfolio | 50.8k $1.0m | Added +10.1k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 50.3k $1.0m | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 50.0k $1.0m | Reduced -2.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 49.9k $1.0m | Added +3.2k |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 48.5k $976.7k | New |
| Man Group plc 0.00% of their portfolio | 46.7k $939.5k | New |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 45.9k $924.0k | Unchanged |
| Verity Asset Management, Inc. 0.43% of their portfolio | 45.3k $910.5k | New |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 45.0k $904.4k | New |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.00% of their portfolio | 43.3k $871.5k | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 41.6k $837.2k | Reduced -2.5k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 41.1k $827.0k | Added +376 |
| Monaco Asset Management SAM 0.30% of their portfolio | 40.0k $804.8k | Reduced -42.5k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 38.2k $768.8k | Added +18.4k |
| Catalyst Funds Management Pty Ltd 0.21% of their portfolio | 37.6k $756.5k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.01% of their portfolio | 37.6k $755.9k | Reduced -11.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 37.0k $745.1k | Reduced -7.3k |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 33.2k $668.0k | Added +2.5k |
| SG Americas Securities, LLC 0.00% of their portfolio | 33.2k $667.0k | Added +24.6k |
| TrueMark Investments, LLC 0.14% of their portfolio | 33.1k $665.9k | Reduced -1.3k |
| Virtu Financial LLC 0.03% of their portfolio | 33.1k $665.0k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 32.9k $662.6k | Unchanged |
| WINTON GROUP Ltd 0.03% of their portfolio | 30.8k $619.2k | Reduced -21.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 30.1k $606.3k | Added +6.7k |
| Cetera Investment Advisers 0.00% of their portfolio | 30.0k $603.1k | Added +12.9k |
| XTX Topco Ltd 0.02% of their portfolio | 29.4k $592.0k | Added +15.8k |
| TWINBEECH CAPITAL LP 0.01% of their portfolio | 29.4k $591.9k | Reduced -6.6k |
| State of Tennessee, Department of Treasury 0.00% of their portfolio | 29.0k $584.2k | Added +15.9k |