SCHRODINGER INC SDGR
COM · Common Stock · CUSIP 80810D103 · ISIN US80810D1037
American life sciences company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Founded1990
- Websiteschrodinger.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($47.7m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $19.29. Options: 12 managers hold calls ($10.3m notional), 11 hold puts ($6.9m).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 198 |
| Q4 2022 | 171 |
| Q1 2023 | 184 |
| Q2 2023 | 241 |
| Q3 2023 | 237 |
| Q4 2023 | 240 |
| Q1 2024 | 224 |
| Q2 2024 | 208 |
| Q3 2024 | 209 |
| Q4 2024 | 213 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 86 | 67 |
| Q2 2023 | 139 | 80 |
| Q3 2023 | 118 | 123 |
| Q4 2023 | 115 | 114 |
| Q1 2024 | 101 | 115 |
| Q2 2024 | 97 | 110 |
| Q3 2024 | 95 | 104 |
| Q4 2024 | 87 | 105 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $16.8m | $19.8m | 1.18 |
| Q2 2024 | $14.4m | $9.1m | 0.63 |
| Q3 2024 | $14.2m | $7.5m | 0.53 |
| Q4 2024 | $10.3m | $6.9m | 0.68 |
Biggest buyers
| Sumitomo Mitsui Trust Group, Inc. | Added | +1.3m |
| Rubric Capital Management LP | Added | +1.3m |
| Amova Asset Management Americas, Inc. | Added | +1.3m |
| UBS Group AG | Added | +350.7k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Added | +334.1k |
| MILLENNIUM MANAGEMENT LLC | Added | +226.5k |
| BlackRock, Inc. | Added | +219.9k |
| GOLDMAN SACHS GROUP INC | Added | +172.0k |
| STATE STREET CORP | Added | +161.0k |
| TWO SIGMA INVESTMENTS, LP | New | +100.5k |
Biggest sellers
| BAILLIE GIFFORD & CO | Reduced | -926.6k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Reduced | -537.9k |
| AMERIPRISE FINANCIAL INC | Reduced | -402.2k |
| CITADEL ADVISORS LLC | Reduced | -400.7k |
| Capital World Investors | Sold out | -340.0k |
| FMR LLC | Reduced | -311.4k |
| MORGAN STANLEY | Reduced | -237.5k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Reduced | -212.9k |
| Russell Investments Group, Ltd. | Reduced | -133.3k |
| ARK Investment Management LLC | Reduced | -127.7k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.8m145.1k shares |
| CITADEL ADVISORS LLC | Added | $1.8m95.5k shares |
| PEAK6 LLC | First filing | $1.5m78.0k shares |
| SIMPLEX TRADING, LLC | Added | $952.0k49.4k shares |
| IMC-Chicago, LLC | Added | $925.9k48.0k shares |
| WOLVERINE TRADING, LLC | Added | $664.3k35.3k shares |
| D. E. Shaw & Co., Inc. | Reduced | $486.1k25.2k shares |
| Walleye Capital LLC | Reduced | $436.0k22.6k shares |
| GROUP ONE TRADING LLC | Reduced | $268.1k13.9k shares |
| Walleye Trading LLC | New | $216.0k11.2k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $2.5m130.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.2m115.3k shares |
| IMC-Chicago, LLC | Added | $613.4k31.8k shares |
| WOLVERINE TRADING, LLC | Reduced | $355.7k18.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $326.0k16.9k shares |
| D. E. Shaw & Co., Inc. | Reduced | $285.5k14.8k shares |
| GROUP ONE TRADING LLC | Added | $229.6k11.9k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $216.0k11.2k shares |
| Walleye Trading LLC | New | $81.0k4.2k shares |
| Walleye Capital LLC | Reduced | $81.0k4.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-07-18 | 12.7% |
| Rubric Capital Management LP 13G · institution +2.8 pts · filed 2026-05-15 | 9.3% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 6.0% |
Fell to 5% or below in the last year: Sumitomo Mitsui Trust Group, Inc. (4.9%, 2026-04-30), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 2 | $1.9m | — |
| Q2 2023 | 0 | — | 3 | $2.4m | — |
| Q3 2023 | 0 | — | 1 | $400.6k | $400.6k |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 5 | $189.7k | $102.4k |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 1 | $27.2k | $27.2k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-10-15 | Dugan Margaret Chief Medical Officer | Sold plan | $27.2k1.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 8.8m $169.7m | Added +219.9k |
| GATES FOUNDATION TRUST 0.32% of their portfolio | 7.0m $134.7m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 6.6m $127.6m | Reduced -95.1k |
| Rubric Capital Management LP 1.75% of their portfolio | 5.0m $96.5m | Added +1.3m |
| Sumitomo Mitsui Trust Group, Inc. 0.05% of their portfolio | 3.5m $67.7m | Added +1.3m |
| Amova Asset Management Americas, Inc. 0.51% of their portfolio | 2.5m $47.5m | Added +1.3m |
| STATE STREET CORP 0.00% of their portfolio | 2.3m $44.7m | Added +161.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 2.3m $44.0m | Added +334.1k |
| ARK Investment Management LLC 0.35% of their portfolio | 2.2m $42.6m | Reduced -127.7k |
| LAZARD ASSET MANAGEMENT LLC 0.05% of their portfolio | 1.7m $32.8m | Added +58.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 1.6m $31.2m | Reduced -537.9k |
| Stephens Investment Management Group LLC 0.42% of their portfolio | 1.6m $31.0m | Added +67.8k |
| MORGAN STANLEY 0.00% of their portfolio | 1.5m $29.7m | Reduced -237.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $25.4m | Reduced -4.0k |
| TOCQUEVILLE ASSET MANAGEMENT L.P. 0.35% of their portfolio | 1.1m $22.1m | Reduced -9.1k |
| BAILLIE GIFFORD & CO 0.02% of their portfolio | 1.1m $20.3m | Reduced -926.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 806.1k $15.5m | Reduced -50.8k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 761.7k $14.7m | Added +226.5k |
| Prosight Management, LP 3.89% of their portfolio | 720.5k $13.9m | Added +20.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 602.6k $11.6m | Added +61.0k |
| Parkman Healthcare Partners LLC 1.45% of their portfolio | 563.1k $10.9m | Added +4.0k |
| FMR LLC 0.00% of their portfolio | 523.8k $10.1m | Reduced -311.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 514.7k $9.9m | Added +172.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 509.7k $9.8m | Added +11.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 411.7k $7.9m | Reduced -27.2k |
| UBS Group AG 0.00% of their portfolio | 397.6k $7.7m | Added +350.7k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 270.4k $5.2m | Added +8.1k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 233.0k $4.5m | Added +17.7k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 185.8k $3.6m | Added +11.3k |
| Legal & General Group Plc 0.00% of their portfolio | 165.9k $3.2m | Added +4.3k |
| Stanley-Laman Group, Ltd. 0.43% of their portfolio | 159.5k $3.1m | Reduced -38.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 158.6k $3.1m | Added +241 |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 150.6k $2.9m | Unchanged |
| Public Sector Pension Investment Board 0.01% of their portfolio | 138.6k $2.7m | Added +21.2k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 138.2k $2.7m | Reduced -402.2k |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 133.8k $2.6m | Reduced -7.9k |
| Invesco Ltd. 0.00% of their portfolio | 131.1k $2.5m | Reduced -5.5k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 126.1k $2.4m | Reduced -133.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 125.5k $2.4m | Reduced -119.9k |
| Swiss National Bank 0.00% of their portfolio | 125.1k $2.4m | Added +1.5k |
| Integrated Advisors Network LLC 0.11% of their portfolio | 117.2k $2.3m | Reduced -17.5k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 108.0k $2.1m | Reduced -400.7k |
| BARCLAYS PLC 0.00% of their portfolio | 104.0k $2.0m | Reduced -3.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 100.5k $1.9m | New |
| ALGERT GLOBAL LLC 0.04% of their portfolio | 91.9k $1.8m | Reduced -34.9k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.01% of their portfolio | 91.2k $1.8m | Reduced -212.9k |
| NATIXIS 0.01% of their portfolio | 90.7k $1.7m | New |
| CITIGROUP INC 0.00% of their portfolio | 90.4k $1.7m | Added +2.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 86.8k $1.7m | Reduced -10.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 84.3k $1.6m | Reduced -120.7k |
| Tejara Capital Ltd 1.02% of their portfolio | 80.9k $1.6m | Reduced -22.3k |
| NORGES BANK 0.00% of their portfolio | 80.1k $1.5m | Reduced -69.3k |
| Monaco Asset Management SAM 0.69% of their portfolio | 80.0k $1.5m | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 78.6k $1.5m | Unchanged |
| PIER 88 INVESTMENT PARTNERS LLC 0.28% of their portfolio | 74.7k $1.4m | Reduced -2.4k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 73.8k $1.4m | Reduced -6.7k |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 72.8k $1.4m | Added +2.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 65.5k $1.3m | Added +2.2k |
| Geneos Wealth Management Inc. 0.04% of their portfolio | 60.0k $1.2m | Added +8.0k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 59.3k $1.1m | Reduced -1.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 59.0k $1.1m | Reduced -527 |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 56.6k $1.1m | Reduced -600 |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio | 50.0k $965.3k | First filing |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio | 46.9k $905.0k | Added +18.6k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 46.1k $889.0k | Reduced -200 |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 43.5k $839.6k | Reduced -984 |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 42.8k $826.0k | Reduced -640 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 42.0k $811.0k | Added +3.4k |
| LPL Financial LLC 0.00% of their portfolio | 41.3k $797.0k | Reduced -16.3k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 37.4k $721.1k | Reduced -22.0k |
| TrueMark Investments, LLC 0.23% of their portfolio | 36.9k $712.7k | Reduced -3.1k |
| Corient Private Wealth LP 0.00% of their portfolio | 35.2k $678.2k | Added +380 |
| NEOS Investment Management LLC 0.02% of their portfolio | 34.8k $671.1k | Added +6.5k |
| Tema ETFs LLC 0.28% of their portfolio | 34.8k $671.1k | First filing |
| MetLife Investment Management, LLC 0.00% of their portfolio | 34.6k $666.5k | Added +1.8k |
| AlphaQuest LLC 0.09% of their portfolio | 34.2k $660.1k | Reduced -9.6k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 32.5k $627.6k | Reduced -44.6k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 31.6k $610.4k | Added +1.2k |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 31.4k $605.0k | Reduced -188 |
| Avanza Fonder AB 0.02% of their portfolio | 29.9k $577.2k | First filing |
| Corebridge Financial, Inc. 0.00% of their portfolio | 29.6k $571.0k | Reduced -2.3k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 28.3k $545.9k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 27.8k $536.9k | Reduced -752 |
| INTECH INVESTMENT MANAGEMENT LLC 0.01% of their portfolio | 27.8k $536.2k | Added +10.6k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 27.6k $531.8k | New |
| Verition Fund Management LLC 0.00% of their portfolio | 27.2k $525.6k | New |
| Louisiana State Employees Retirement System 0.01% of their portfolio | 26.8k $517.0k | Unchanged |
| Amundi 0.00% of their portfolio | 26.8k $543.9k | Added +17.8k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 25.6k $494.7k | Added +1.8k |
| ADAR1 Capital Management, LLC 0.10% of their portfolio | 25.1k $485.1k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 24.5k $472.6k | New |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 23.9k $460.5k | Reduced -22.8k |
| Creative Planning 0.00% of their portfolio | 22.8k $439.9k | Added +607 |
| GREENWOOD CAPITAL ASSOCIATES LLC 0.06% of their portfolio | 22.5k $434.5k | Reduced -31 |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 21.8k $420.9k | Added +3.3k |
| YOUSIF CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 21.3k $411.6k | Reduced -532 |
| BRANDYWINE MANAGERS, LLC 0.42% of their portfolio | 20.9k $402.9k | Unchanged |
| SEI INVESTMENTS CO 0.00% of their portfolio | 20.3k $391.7k | Added +1.8k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 20.1k $386.0k | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 20.1k $386.8k | Added +2.4k |