SAVARA INC SVRA
COM · Common Stock · CUSIP 805111101 · ISIN US8051111016
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersAustin, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($252.5k this quarter). Holder counts are more reliable. Shares outstanding: 204.7m as of 2026-03-13, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $5.46. Options: 5 managers hold calls ($781.9k notional), 3 hold puts ($342.3k).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 56 |
| Q4 2022 | 56 |
| Q1 2023 | 70 |
| Q2 2023 | 78 |
| Q3 2023 | 85 |
| Q4 2023 | 99 |
| Q1 2024 | 121 |
| Q2 2024 | 134 |
| Q3 2024 | 127 |
| Q4 2024 | 137 |
| Q1 2025 | 138 |
| Q2 2025 | 125 |
| Q3 2025 | 126 |
| Q4 2025 | 148 |
| Q1 2026 | 187 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 89 | 45 |
| Q3 2024 | 72 | 50 |
| Q4 2024 | 74 | 50 |
| Q1 2025 | 70 | 54 |
| Q2 2025 | 61 | 62 |
| Q3 2025 | 63 | 64 |
| Q4 2025 | 89 | 53 |
| Q1 2026 | 118 | 58 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $254.9k | $1.1k | 0.00 |
| Q3 2025 | $521.5k | $130.7k | 0.25 |
| Q4 2025 | $959.4k | $294.3k | 0.31 |
| Q1 2026 | $781.9k | $342.3k | 0.44 |
Biggest buyers
| STATE STREET CORP | Added | +2.4m |
| Pictet Asset Management Holding SA | New | +2.3m |
| SILVERARC CAPITAL MANAGEMENT, LLC | New | +1.4m |
| Polar Capital Holdings Plc | Added | +1.2m |
| Vestal Point Capital, LP | Added | +994.1k |
| Spruce Street Capital LP | Added | +972.1k |
| ALGERT GLOBAL LLC | New | +864.6k |
| ORBIMED ADVISORS LLC | New | +635.0k |
| Moody Aldrich Partners LLC | New | +614.3k |
| Integral Health Asset Management, LLC | New | +600.0k |
Biggest sellers
| PERCEPTIVE ADVISORS LLC | Sold out | -2.4m |
| Siren, L.L.C. | Sold out | -1.0m |
| MORGAN STANLEY | Reduced | -551.6k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -535.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -472.2k |
| Invesco Ltd. | Reduced | -465.6k |
| SPHERA FUNDS MANAGEMENT LTD. | Reduced | -439.0k |
| SummitTX Capital, L.P. | Sold out | -373.0k |
| Affinity Asset Advisors, LLC | Reduced | -285.0k |
| BARCLAYS PLC | Reduced | -279.1k |
Biggest calls
| JANE STREET GROUP, LLC | Added | $522.0k95.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $151.2k27.7k shares |
| CITADEL ADVISORS LLC | Reduced | $77.5k14.2k shares |
| SIMPLEX TRADING, LLC | Added | $18.0k3.3k shares |
| GROUP ONE TRADING LLC | Reduced | $13.1k2.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $171.4k31.4k shares |
| JANE STREET GROUP, LLC | Added | $115.8k21.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $55.1k10.1k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Growth Equity Opportunities 17, LLC
13D · may seek influence
filed 2025-11-14
Stated purposeGEO acquired the GEO Shares for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, GEO and the other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; (c) A sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries; (d) Any change in the present board of directors or … Full filing |
12.0% |
| Bain Capital Life Sciences Fund II, L.P. 13D · may seek influence filed 2025-03-27 | 10.0% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor +2.6 pts · filed 2026-02-17 | 9.9% |
| Farallon Capital Partners, L.P. 13G · passive investor -3.1 pts · filed 2026-02-05 | 6.9% |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 13G · institution filed 2026-08-14 | 6.8% |
| Flynn James E 13G · passive investor new · filed 2025-11-05 | 6.7% |
| TCG Crossover GP I, LLC 13G · passive investor filed 2026-02-17 | 6.1% |
| BlackRock, Inc. 13G · institution +0.6 pts · filed 2026-01-21 | 5.4% |
Fell to 5% or below in the last year: Nantahala Capital Management, LLC (3.6%, 2026-02-13), Frazier Life Sciences Public Fund, L.P. (4.1%, 2026-02-13), Vestal Point Capital, LP (2.3%, 2025-11-14)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 2 | $347.0k | 3 | $290.9k | — |
| Q1 2025 | 1 | $417.0k | 0 | — | — |
| Q2 2025 | 2 | $119.2k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $121.2k | — |
| Q1 2026 | 0 | — | 0 | — | — |
None reported in Q1 2026.
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| NEA Management Company, LLC 7.60% of their portfolio | 24.5m $133.6m | Unchanged |
| Bain Capital Life Sciences Investors, LLC 8.67% of their portfolio | 17.6m $96.1m | Unchanged |
| Venrock Adviser, LLC 2.80% of their portfolio | 13.7m $75.0m | Unchanged |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.87% of their portfolio | 13.6m $74.1m | Unchanged |
| TCG Crossover Management, LLC 1.93% of their portfolio | 12.4m $67.5m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 11.3m $61.6m | Added +193.9k |
| Frazier Life Sciences Management, L.P. 1.37% of their portfolio | 9.7m $53.1m | Reduced -141.4k |
| Polar Capital Holdings Plc 0.23% of their portfolio | 9.5m $52.1m | Added +1.2m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 7.8m $42.5m | First filing |
| Nantahala Capital Management, LLC 2.50% of their portfolio | 7.3m $40.1m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 6.7m $36.6m | Added +2.4m |
| RTW INVESTMENTS, LP 0.32% of their portfolio | 6.0m $32.5m | Unchanged |
| MARSHALL WACE, LLP 0.03% of their portfolio | 4.5m $24.6m | Reduced -45.6k |
| Woodline Partners LP 0.09% of their portfolio | 4.2m $23.2m | Added +479 |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.6m $19.6m | Added +176.7k |
| Spruce Street Capital LP 4.44% of their portfolio | 3.4m $18.5m | Added +972.1k |
| EMERALD ADVISERS, LLC 0.58% of their portfolio | 3.4m $18.4m | Reduced -124.2k |
| Rosalind Advisors, Inc. 7.17% of their portfolio | 3.2m $17.5m | Reduced -200.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 2.7m $14.8m | Added +35.8k |
| Vestal Point Capital, LP 0.40% of their portfolio | 2.6m $14.2m | Added +994.1k |
| Affinity Asset Advisors, LLC 0.80% of their portfolio | 2.5m $13.7m | Reduced -285.0k |
| EMERALD MUTUAL FUND ADVISERS TRUST 0.63% of their portfolio | 2.4m $12.9m | Reduced -27.8k |
| Pictet Asset Management Holding SA 0.01% of their portfolio | 2.3m $12.4m | New |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 2.1m $11.5m | Added +442.5k |
| NAN FUNG TRINITY (HK) LTD 1.10% of their portfolio | 1.8m $10.1m | Added +153.8k |
| MORGAN STANLEY 0.00% of their portfolio | 1.8m $9.8m | Reduced -551.6k |
| SUPERSTRING CAPITAL MANAGEMENT LP 6.19% of their portfolio | 1.6m $8.7m | Added +590.6k |
| ADAR1 Capital Management, LLC 0.48% of their portfolio | 1.5m $8.0m | Added +59.1k |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.92% of their portfolio | 1.4m $7.8m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.4m $7.5m | First filing |
| Longaeva Partners L.P. 0.33% of their portfolio | 1.3m $7.0m | Added +29.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.2m $6.5m | Added +112.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 1.1m $6.2m | Reduced -21.4k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.01% of their portfolio | 1.1m $5.7m | Reduced -8.3k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 1.0m $5.5m | First filing |
| ALGERT GLOBAL LLC 0.07% of their portfolio | 864.6k $4.7m | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 848.4k $4.6m | Added +23.7k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 798.7k $4.4m | Added +24.2k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 756.8k $4.1m | Added +5.5k |
| SPHERA FUNDS MANAGEMENT LTD. 0.69% of their portfolio | 739.2k $4.0m | Reduced -439.0k |
| Swedbank AB 0.00% of their portfolio | 700.0k $3.8m | Reduced -150.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 652.7k $3.6m | Added +320.6k |
| F/m Investments LLC 0.24% of their portfolio | 651.0k $3.6m | Reduced -27.8k |
| ORBIMED ADVISORS LLC 0.08% of their portfolio | 635.0k $3.5m | New |
| Moody Aldrich Partners LLC 0.60% of their portfolio | 614.3k $3.4m | New |
| Sio Capital Management, LLC 0.48% of their portfolio | 613.9k $3.4m | Unchanged |
| KVP Capital Advisors, LP 2.47% of their portfolio | 605.3k $3.3m | Unchanged |
| Integral Health Asset Management, LLC 0.17% of their portfolio | 600.0k $3.3m | New |
| UBS Group AG 0.00% of their portfolio | 596.7k $3.3m | Added +393.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 588.2k $3.2m | Added +164.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 580.1k $3.2m | Added +63.5k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 463.0k $2.5m | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 431.0k $2.4m | Reduced -153.3k |
| Eversept Partners, LP 0.14% of their portfolio | 384.3k $2.1m | Added +214.1k |
| XTX Topco Ltd 0.04% of their portfolio | 379.4k $2.1m | Added +354.7k |
| Sofinnova Investments, Inc. 0.10% of their portfolio | 364.8k $2.0m | Added +60.0k |
| Nuveen, LLC 0.00% of their portfolio | 343.6k $1.9m | Added +71.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 309.7k $1.7m | Reduced -3.2k |
| WEDGE CAPITAL MANAGEMENT L L P/NC 0.03% of their portfolio | 308.0k $1.7m | New |
| Seven Fleet Capital Management LP 0.51% of their portfolio | 295.7k $1.6m | Added +232.9k |
| HighVista Strategies LLC 0.38% of their portfolio | 251.0k $1.4m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 240.6k $1.3m | Added +209.4k |
| Invesco Ltd. 0.00% of their portfolio | 223.0k $1.2m | Reduced -465.6k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 205.1k $1.0m | New |
| Walleye Capital LLC 0.01% of their portfolio | 195.1k $1.1m | Added +45.0k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 189.0k $1.0m | Added +99.1k |
| Squarepoint Ops LLC 0.00% of their portfolio | 170.8k $932.7k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 157.1k $858.0k | Added +4.4k |
| Aquatic Capital Management LLC 0.02% of their portfolio | 153.1k $836.2k | Added +70.1k |
| Swiss National Bank 0.00% of their portfolio | 136.8k $746.9k | New |
| Verdad Advisers, LP 0.79% of their portfolio | 128.4k $700.9k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 127.0k $766.1k | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 122.9k $670.8k | Added +48.0k |
| Trexquant Investment LP 0.00% of their portfolio | 114.2k $623.5k | New |
| GLENMEDE TRUST CO NA 0.00% of their portfolio | 105.3k $574.8k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 101.5k $555.0k | Added +31.9k |
| GSA CAPITAL PARTNERS LLP 0.03% of their portfolio | 93.7k $512.0k | Reduced -47.0k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 91.7k $500.7k | First filing |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio | 90.0k $491.4k | Unchanged |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 88.7k $484.4k | New |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 87.6k $478.2k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 86.9k $474.6k | Reduced -80.7k |
| PROFUND ADVISORS LLC 0.02% of their portfolio | 85.0k $464.0k | Added +49.8k |
| OPTIMIZE FINANCIAL INC. 0.23% of their portfolio | 84.1k $459.2k | New |
| Cresset Asset Management, LLC 0.00% of their portfolio | 83.5k $455.8k | Added +150 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 81.3k $438.4k | Added +10.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 80.7k $407.6k | Added +7.7k |
| EntryPoint Capital, LLC 0.12% of their portfolio | 73.9k $403.4k | Added +33.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 71.6k $390.9k | Reduced -472.2k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 69.4k $379.2k | Reduced -9.1k |
| FMR LLC 0.00% of their portfolio | 69.0k $376.9k | Added +41.2k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 68.2k $372.2k | Added +24.6k |
| FIFTH THIRD BANCORP 0.00% of their portfolio | 66.4k $362.7k | New |
| Susquehanna Portfolio Strategies, LLC 0.00% of their portfolio | 60.0k $327.5k | Added +505 |
| Creative Planning 0.00% of their portfolio | 59.8k $326.7k | Added +4.1k |
| SG Americas Securities, LLC 0.00% of their portfolio | 57.4k $313.0k | Added +11.9k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 55.2k $301.3k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 52.7k $287.8k | New |
| Avidity Partners Management LP 0.03% of their portfolio | 50.0k $262.0k | New |
| Sivia Capital Partners, LLC 0.05% of their portfolio | 48.5k $264.8k | Reduced -7 |