SAVARA INC SVRA
COM · Common Stock · CUSIP 805111101 · ISIN US8051111016
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersAustin, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($292.6k this quarter). Holder counts are more reliable. Shares outstanding: 203.5m as of 2025-11-12, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.03. Options: 5 managers hold calls ($959.4k notional), 3 hold puts ($294.3k).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 56 |
| Q4 2022 | 56 |
| Q1 2023 | 70 |
| Q2 2023 | 78 |
| Q3 2023 | 85 |
| Q4 2023 | 99 |
| Q1 2024 | 121 |
| Q2 2024 | 134 |
| Q3 2024 | 127 |
| Q4 2024 | 137 |
| Q1 2025 | 138 |
| Q2 2025 | 125 |
| Q3 2025 | 126 |
| Q4 2025 | 148 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 78 | 33 |
| Q2 2024 | 89 | 45 |
| Q3 2024 | 72 | 50 |
| Q4 2024 | 74 | 50 |
| Q1 2025 | 70 | 54 |
| Q2 2025 | 61 | 62 |
| Q3 2025 | 63 | 64 |
| Q4 2025 | 89 | 53 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $219.5k | $11.4k | 0.05 |
| Q2 2025 | $254.9k | $1.1k | 0.00 |
| Q3 2025 | $521.5k | $130.7k | 0.25 |
| Q4 2025 | $959.4k | $294.3k | 0.31 |
Biggest buyers
| Polar Capital Holdings Plc | New | +8.3m |
| RTW INVESTMENTS, LP | New | +6.0m |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Added | +5.6m |
| MARSHALL WACE, LLP | New | +4.6m |
| Woodline Partners LP | Added | +4.0m |
| BlackRock, Inc. | Added | +2.6m |
| PERCEPTIVE ADVISORS LLC | New | +2.4m |
| STATE STREET CORP | Added | +2.0m |
| VANGUARD GROUP INC | Added | +1.7m |
| NAN FUNG TRINITY (HK) LTD | New | +1.7m |
Biggest sellers
| Vestal Point Capital, LP | Reduced | -2.4m |
| Sofinnova Investments, Inc. | Reduced | -2.1m |
| Frazier Life Sciences Management, L.P. | Reduced | -1.6m |
| Nantahala Capital Management, LLC | Reduced | -1.4m |
| ROYAL BANK OF CANADA | Reduced | -650.2k |
| Rosalind Advisors, Inc. | Reduced | -596.3k |
| ADAR1 Capital Management, LLC | Reduced | -582.8k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -530.5k |
| UBS Group AG | Reduced | -492.9k |
| Point72 Asset Management, L.P. | Sold out | -419.8k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $602.4k99.9k shares |
| CITADEL ADVISORS LLC | New | $177.9k29.5k shares |
| JANE STREET GROUP, LLC | New | $97.1k16.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $69.9k11.6k shares |
| SIMPLEX TRADING, LLC | Added | $12.1k2.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $133.9k22.2k shares |
| JANE STREET GROUP, LLC | New | $83.2k13.8k shares |
| SIMPLEX TRADING, LLC | Added | $77.2k12.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Growth Equity Opportunities 17, LLC
13D · may seek influence
filed 2025-11-14
Stated purposeGEO acquired the GEO Shares for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, GEO and the other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; (c) A sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries; (d) Any change in the present board of directors or … Full filing |
12.0% |
| Bain Capital Life Sciences Fund II, L.P. 13D · may seek influence filed 2025-03-27 | 10.0% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor +2.6 pts · filed 2026-02-17 | 9.9% |
| Farallon Capital Partners, L.P. 13G · passive investor -3.1 pts · filed 2026-02-05 | 6.9% |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 13G · institution filed 2026-08-14 | 6.8% |
| Flynn James E 13G · passive investor new · filed 2025-11-05 | 6.7% |
| TCG Crossover GP I, LLC 13G · passive investor filed 2026-02-17 | 6.1% |
| BlackRock, Inc. 13G · institution +0.6 pts · filed 2026-01-21 | 5.4% |
Fell to 5% or below in the last year: Nantahala Capital Management, LLC (3.6%, 2026-02-13), Frazier Life Sciences Public Fund, L.P. (4.1%, 2026-02-13), Vestal Point Capital, LP (2.3%, 2025-11-14)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 2 | $347.0k | 3 | $290.9k | — |
| Q1 2025 | 1 | $417.0k | 0 | — | — |
| Q2 2025 | 2 | $119.2k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $121.2k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-12-19 | RAMSAY DAVID A Director | Sold | $121.2k20.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| NEA Management Company, LLC 7.52% of their portfolio | 24.5m $147.6m | Unchanged |
| Bain Capital Life Sciences Investors, LLC 8.13% of their portfolio | 17.6m $106.1m | Unchanged |
| Venrock Adviser, LLC 4.09% of their portfolio | 13.7m $82.9m | Added +1.1m |
| DEERFIELD MANAGEMENT COMPANY, L.P. 1.05% of their portfolio | 13.6m $81.8m | Added +5.6m |
| TCG Crossover Management, LLC 2.47% of their portfolio | 12.4m $74.5m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 11.1m $66.9m | Added +2.6m |
| VANGUARD GROUP INC 0.00% of their portfolio | 10.0m $60.6m | Added +1.7m |
| Frazier Life Sciences Management, L.P. 1.60% of their portfolio | 9.9m $59.5m | Reduced -1.6m |
| Polar Capital Holdings Plc 0.23% of their portfolio | 8.3m $50.1m | New |
| Nantahala Capital Management, LLC 2.64% of their portfolio | 7.3m $44.3m | Reduced -1.4m |
| RTW INVESTMENTS, LP 0.36% of their portfolio | 6.0m $35.9m | New |
| MARSHALL WACE, LLP 0.03% of their portfolio | 4.6m $27.5m | New |
| STATE STREET CORP 0.00% of their portfolio | 4.3m $26.1m | Added +2.0m |
| Woodline Partners LP 0.10% of their portfolio | 4.2m $25.6m | Added +4.0m |
| EMERALD ADVISERS, LLC 0.65% of their portfolio | 3.5m $21.1m | Reduced -33.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.4m $20.6m | Added +622.1k |
| Rosalind Advisors, Inc. 7.48% of their portfolio | 3.4m $20.5m | Reduced -596.3k |
| Affinity Asset Advisors, LLC 1.21% of their portfolio | 2.8m $16.9m | Added +1.3m |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 2.7m $16.1m | Added +30.9k |
| Spruce Street Capital LP 4.80% of their portfolio | 2.4m $14.5m | First filing |
| PERCEPTIVE ADVISORS LLC 0.27% of their portfolio | 2.4m $14.5m | New |
| EMERALD MUTUAL FUND ADVISERS TRUST 0.70% of their portfolio | 2.4m $14.5m | Added +245.1k |
| MORGAN STANLEY 0.00% of their portfolio | 2.3m $14.1m | Added +420.1k |
| NAN FUNG TRINITY (HK) LTD 0.81% of their portfolio | 1.7m $10.2m | New |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.7m $10.1m | Added +1.3m |
| Vestal Point Capital, LP 0.36% of their portfolio | 1.6m $9.7m | Reduced -2.4m |
| ADAR1 Capital Management, LLC 0.63% of their portfolio | 1.4m $8.5m | Reduced -582.8k |
| Longaeva Partners L.P. 0.89% of their portfolio | 1.2m $7.5m | New |
| SPHERA FUNDS MANAGEMENT LTD. 1.48% of their portfolio | 1.2m $7.1m | Reduced -172.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 1.2m $7.0m | Added +197.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.1m $6.5m | Added +130.9k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.01% of their portfolio | 1.1m $6.4m | New |
| Siren, L.L.C. 0.18% of their portfolio | 1.0m $6.0m | New |
| SUPERSTRING CAPITAL MANAGEMENT LP 3.21% of their portfolio | 995.4k $6.0m | Reduced -313.9k |
| Swedbank AB 0.00% of their portfolio | 850.0k $5.1m | Added +300.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 824.7k $5.0m | Reduced -26.3k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 774.5k $4.7m | Added +106.4k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 751.3k $4.5m | Reduced -105.3k |
| Invesco Ltd. 0.00% of their portfolio | 688.6k $4.2m | Added +517.3k |
| F/m Investments LLC 0.16% of their portfolio | 678.8k $4.1m | Added +245.1k |
| Sio Capital Management, LLC 0.61% of their portfolio | 613.9k $3.7m | Reduced -113.0k |
| KVP Capital Advisors, LP 3.77% of their portfolio | 605.3k $3.6m | First filing |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 584.3k $3.5m | Reduced -21.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 543.8k $3.3m | Added +522.4k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 535.0k $3.2m | Reduced -309.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 516.6k $3.1m | Reduced -145.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 423.6k $2.6m | Added +303.6k |
| SummitTX Capital, L.P. 0.07% of their portfolio | 373.0k $2.2m | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 332.1k $2.0m | Added +72.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 312.9k $1.9m | Added +39.5k |
| BARCLAYS PLC 0.00% of their portfolio | 306.9k $1.9m | Added +130.4k |
| Sofinnova Investments, Inc. 0.08% of their portfolio | 304.8k $1.8m | Reduced -2.1m |
| Nuveen, LLC 0.00% of their portfolio | 272.6k $1.6m | Added +35.8k |
| UBS Group AG 0.00% of their portfolio | 202.9k $1.2m | Reduced -492.9k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 188.2k $1.1m | New |
| Eversept Partners, LP 0.06% of their portfolio | 170.2k $1.0m | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 170.1k $1.0m | Reduced -530.5k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 167.6k $1.0m | Added +83.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 152.8k $921.2k | Reduced -4.8k |
| Walleye Capital LLC 0.01% of their portfolio | 150.1k $905.0k | Added +59.1k |
| GSA CAPITAL PARTNERS LLP 0.07% of their portfolio | 140.8k $849.0k | Reduced -231.7k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 127.0k $766.1k | Added +8.2k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio | 90.0k $549.9k | Reduced -20.0k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 89.9k $541.8k | New |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.00% of their portfolio | 86.2k $519.5k | New |
| Cresset Asset Management, LLC 0.00% of their portfolio | 83.3k $502.5k | New |
| Aquatic Capital Management LLC 0.01% of their portfolio | 83.1k $501.0k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 78.6k $473.7k | Added +18.2k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 74.9k $451.5k | Reduced -19.0k |
| OXFORD ASSET MANAGEMENT LLP 0.16% of their portfolio | 74.1k $446.9k | Not comparable |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 73.1k $440.5k | Reduced -54.6k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 71.0k $428.6k | Added +17.8k |
| Jump Financial, LLC 0.01% of their portfolio | 70.7k $426.3k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 69.5k $420.0k | Added +2.1k |
| Virtu Financial LLC 0.02% of their portfolio | 65.6k $396.0k | New |
| Seven Fleet Capital Management LP 0.26% of their portfolio | 62.8k $378.5k | First filing |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 60.6k $365.6k | Unchanged |
| Susquehanna Portfolio Strategies, LLC 0.01% of their portfolio | 59.5k $358.6k | Added +19.6k |
| Graham Capital Management, L.P. 0.01% of their portfolio | 56.0k $337.8k | Added +2.6k |
| Creative Planning 0.00% of their portfolio | 55.7k $336.0k | Added +11.5k |
| BANK OF NOVA SCOTIA 0.00% of their portfolio | 51.7k $311.8k | New |
| Sivia Capital Partners, LLC 0.06% of their portfolio | 48.5k $292.5k | Added +7 |
| DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD. 0.06% of their portfolio | 46.0k $277.4k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 45.5k $275.0k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 43.5k $262.6k | Added +5.1k |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 41.7k $251.2k | Added +8.5k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 41.0k $247.0k | Reduced -5.3k |
| EntryPoint Capital, LLC 0.10% of their portfolio | 40.7k $245.5k | Reduced -40.9k |
| Caitong International Asset Management Co., Ltd 0.06% of their portfolio | 39.6k $239.1k | Added +37.7k |
| Virtus Investment Advisers, LLC 0.06% of their portfolio | 38.4k $231.8k | Reduced -11.9k |
| Jain Global LLC 0.00% of their portfolio | 37.7k $227.4k | Reduced -1.8k |
| Brooklyn Investment Group 0.01% of their portfolio | 36.8k $233.0k | Reduced -61.8k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 36.6k $220.4k | Added +22.7k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 35.1k $211.9k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 34.9k $210.3k | Added +9.1k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 33.9k $204.6k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 33.2k $199.9k | Added +2.9k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 32.7k $197.0k | Added +2.1k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 31.2k $188.2k | Added +6.0k |
| FMR LLC 0.00% of their portfolio | 27.8k $167.9k | Added +20.6k |