SAREPTA THERAPEUTICS INC SRPT
COM · Common Stock · CUSIP 803607100 · ISIN US8036071004
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, MA
- Founded1980
- Websitesarepta.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($13.2m this quarter). Holder counts are more reliable. Shares outstanding: 95.5m as of 2024-11-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $124.73. Options: 29 managers hold calls ($285.3m notional), 27 hold puts ($239.6m).
Trends to Q3 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 376 |
| Q4 2022 | 414 |
| Q1 2023 | 427 |
| Q2 2023 | 406 |
| Q3 2023 | 396 |
| Q4 2023 | 397 |
| Q1 2024 | 416 |
| Q2 2024 | 486 |
| Q3 2024 | 460 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 199 | 169 |
| Q1 2023 | 219 | 183 |
| Q2 2023 | 204 | 205 |
| Q3 2023 | 201 | 180 |
| Q4 2023 | 181 | 206 |
| Q1 2024 | 215 | 178 |
| Q2 2024 | 291 | 175 |
| Q3 2024 | 225 | 237 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2023 | $715.7m | $383.4m | 0.54 |
| Q1 2024 | $656.0m | $204.9m | 0.31 |
| Q2 2024 | $728.7m | $324.9m | 0.45 |
| Q3 2024 | $285.3m | $239.6m | 0.84 |
Biggest buyers
| Capital International Investors | Added | +1.9m |
| GROUPAMA ASSET MANAGMENT | New | +1.3m |
| JPMORGAN CHASE & CO | Added | +710.2k |
| WELLINGTON MANAGEMENT GROUP LLP | Added | +665.1k |
| Camber Capital Management LP | Added | +625.0k |
| JANUS HENDERSON GROUP PLC | Added | +543.1k |
| FIRST TRUST ADVISORS LP | Added | +363.0k |
| ORBIMED ADVISORS LLC | Added | +308.5k |
| BRAIDWELL LP | Added | +288.5k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | Added | +285.0k |
Biggest sellers
| MORGAN STANLEY | Reduced | -1.7m |
| EcoR1 Capital, LLC | Sold out | -1.4m |
| Paradigm Biocapital Advisors LP | Sold out | -947.6k |
| JANE STREET GROUP, LLC | Reduced | -825.1k |
| FMR LLC | Reduced | -624.8k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -550.2k |
| TWO SIGMA ADVISERS, LP | Reduced | -478.8k |
| Avoro Capital Advisors LLC | Reduced | -444.4k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -339.5k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Reduced | -249.6k |
Biggest calls
| Twin Tree Management, LP | Added | $72.9m583.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $54.5m436.6k shares |
| CITADEL ADVISORS LLC | Reduced | $38.5m308.0k shares |
| GROUP ONE TRADING LLC | Reduced | $15.5m124.3k shares |
| JPMORGAN CHASE & CO | Added | $14.4m115.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $9.6m76.8k shares |
| JANE STREET GROUP, LLC | Reduced | $9.2m73.8k shares |
| Balyasny Asset Management L.P. | Reduced | $7.5m60.0k shares |
| GOLDMAN SACHS GROUP INC | New | $7.1m57.1k shares |
| Parallax Volatility Advisers, L.P. | Reduced | $6.7m53.6k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $41.1m329.0k shares |
| JPMORGAN CHASE & CO | New | $37.5m300.0k shares |
| Twin Tree Management, LP | Added | $26.9m215.7k shares |
| GROUP ONE TRADING LLC | Added | $22.2m177.8k shares |
| CITADEL ADVISORS LLC | Reduced | $20.9m167.6k shares |
| JANE STREET GROUP, LLC | Added | $19.2m154.0k shares |
| LMR Partners LLP | Reduced | $11.0m87.7k shares |
| GOLDMAN SACHS GROUP INC | New | $10.6m85.1k shares |
| CITIGROUP INC | Added | $7.4m58.9k shares |
| GTS SECURITIES LLC | Added | $5.7m46.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +3.2 pts · filed 2026-07-30 | 15.8% |
| STATE STREET CORP 13G · institution +3.0 pts · filed 2026-08-07 | 8.4% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.6 pts · filed 2026-07-31 | 8.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.1% |
| AQR CAPITAL MANAGEMENT LLC 13G · institution -2.7 pts · filed 2026-08-13 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), D. E. SHAW & CO, L.P. (1.9%, 2025-11-14)
Insider purchases and sales in Q3 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2022 | 0 | — | 1 | $94.3k | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 1 | $7.4m | 1 | $1.6m | — |
| Q4 2023 | 2 | $5.9m | 0 | — | — |
| Q1 2024 | 0 | — | 6 | $3.0m | — |
| Q2 2024 | 0 | — | 3 | $8.7m | $8.7m |
| Q3 2024 | 1 | $5.0m | 1 | $822.1k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-08-30 | Estepan Ian Michael Chief Financial Officer | Sold | $822.1k6.0k shares |
| 2024-08-16 | Chambers Michael Andrew Director · By Revocable Trust | Bought | $5.0m37.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.03% of their portfolio | 11.0m $1.4bn | First filing |
| VANGUARD GROUP INC 0.02% of their portfolio | 9.0m $1.1bn | Reduced -68.1k |
| Capital International Investors 0.15% of their portfolio | 6.3m $781.7m | Added +1.9m |
| JPMORGAN CHASE & CO 0.02% of their portfolio | 4.4m $549.2m | Added +710.2k |
| JANUS HENDERSON GROUP PLC 0.28% of their portfolio | 4.4m $544.4m | Added +543.1k |
| STATE STREET CORP 0.02% of their portfolio | 4.3m $533.4m | Added +129.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.06% of their portfolio | 2.7m $340.5m | Added +665.1k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 1.77% of their portfolio | 2.6m $322.2m | Added +285.0k |
| Avoro Capital Advisors LLC 4.65% of their portfolio | 2.6m $319.2m | Reduced -444.4k |
| Bank of New York Mellon Corp 0.05% of their portfolio | 2.1m $264.6m | Reduced -11.7k |
| T. Rowe Price Investment Management, Inc. 0.15% of their portfolio | 1.9m $243.1m | Reduced -12.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.7m $211.9m | Added +44.3k |
| DEUTSCHE BANK AG\ 0.07% of their portfolio | 1.5m $182.7m | Reduced -110.4k |
| GROUPAMA ASSET MANAGMENT 0.03% of their portfolio | 1.3m $1.2m | New |
| FMR LLC 0.01% of their portfolio | 1.2m $154.3m | Reduced -624.8k |
| Casdin Capital, LLC 8.94% of their portfolio | 1.1m $134.1m | Unchanged |
| Pictet Asset Management Holding SA 0.14% of their portfolio | 1.1m $131.2m | Added +93.8k |
| NORGES BANK 0.02% of their portfolio | 1.0m $125.7m | Added +82.0k |
| ORBIMED ADVISORS LLC 2.18% of their portfolio | 954.5k $119.2m | Added +308.5k |
| MORGAN STANLEY 0.01% of their portfolio | 953.1k $119.0m | Reduced -1.7m |
| CITADEL ADVISORS LLC 0.12% of their portfolio | 926.2k $115.7m | Added +150.4k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 783.0k $97.8m | Added +61.6k |
| Camber Capital Management LP 3.76% of their portfolio | 775.0k $96.8m | Added +625.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.36% of their portfolio | 753.8k $94.1m | Added +63.4k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 655.6k $81.9m | Reduced -12.4k |
| Boxer Capital, LLC 3.98% of their portfolio | 650.0k $81.2m | Unchanged |
| Erste Asset Management GmbH 0.95% of their portfolio | 636.1k $79.4m | Added +114.7k |
| ALKEON CAPITAL MANAGEMENT LLC 0.43% of their portfolio | 633.8k $79.2m | Added +75.0k |
| Thrivent Financial for Lutherans 0.15% of their portfolio | 624.9k $78.0m | Reduced -19.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 611.7k $76.4m | Added +7.0k |
| ROYAL BANK OF CANADA 0.02% of their portfolio | 586.0k $73.2m | Added +90.4k |
| FEDERATED HERMES, INC. 0.14% of their portfolio | 508.8k $63.5m | Added +507 |
| Invesco Ltd. 0.01% of their portfolio | 482.2k $60.2m | Added +101.8k |
| Nuveen Asset Management, LLC 0.02% of their portfolio | 474.2k $59.2m | Reduced -9.0k |
| FIRST TRUST ADVISORS LP 0.06% of their portfolio | 464.9k $58.1m | Added +363.0k |
| BARCLAYS PLC 0.03% of their portfolio | 459.9k $57.4m | Added +59.0k |
| Aberdeen Group plc 0.10% of their portfolio | 431.1k $53.9m | Added +101.3k |
| MIZUHO MARKETS AMERICAS LLC 1.22% of their portfolio | 399.1k $49.8m | Added +72.8k |
| EAGLE ASSET MANAGEMENT INC 0.23% of their portfolio | 371.4k $45.2m | Reduced -34.6k |
| BRAIDWELL LP 1.31% of their portfolio | 370.4k $46.3m | Added +288.5k |
| UBS Group AG 0.01% of their portfolio | 364.2k $45.5m | Added +13.4k |
| Fiera Capital Corp 0.14% of their portfolio | 360.0k $45.0m | Reduced -22.6k |
| Amundi 0.02% of their portfolio | 357.9k $42.9m | Added +25.0k |
| Assenagon Asset Management S.A. 0.09% of their portfolio | 350.1k $43.7m | Reduced -9.6k |
| Bellevue Group AG 0.70% of their portfolio | 344.3k $43.0m | Added +92.0k |
| Balyasny Asset Management L.P. 0.10% of their portfolio | 324.3k $40.5m | Reduced -208.6k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 317.3k $39.6m | Added +8.9k |
| Man Group plc 0.11% of their portfolio | 311.3k $38.9m | Reduced -75.1k |
| Rock Springs Capital Management LP 1.25% of their portfolio | 307.5k $38.4m | Added +23.5k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 301.0k $37.6m | Reduced -138.6k |
| FRED ALGER MANAGEMENT, LLC 0.17% of their portfolio | 286.9k $35.8m | Reduced -31.4k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 280.2k $35.0m | Added +24.8k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.06% of their portfolio | 275.0k $34.3m | Reduced -125.0k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.59% of their portfolio | 273.0k $34.1m | Added +44.4k |
| RHUMBLINE ADVISERS 0.03% of their portfolio | 270.9k $33.8m | Reduced -69 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 268.2k $33.5m | Reduced -33.3k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 267.0k $33.4m | Reduced -96.0k |
| BANK OF NOVA SCOTIA 0.06% of their portfolio | 252.8k $31.6m | Reduced -57 |
| Clearbridge Investments, LLC 0.02% of their portfolio | 237.1k $29.6m | Reduced -277 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 236.5k $29.5m | Reduced -103.5k |
| Alyeska Investment Group, L.P. 0.15% of their portfolio | 235.2k $29.4m | Added +175.2k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 235.2k $29.3m | Reduced -8.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.04% of their portfolio | 230.5k $28.8m | Reduced -121.5k |
| Ensign Peak Advisors, Inc 0.05% of their portfolio | 225.3k $28.1m | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.03% of their portfolio | 225.0k $28.1m | Reduced -97.8k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 219.0k $27.4m | Added +4.6k |
| Palo Alto Investors LP 3.41% of their portfolio | 210.3k $26.3m | Added +8.6k |
| SOROS FUND MANAGEMENT LLC 0.51% of their portfolio | 206.6k $25.8m | New |
| CAPITAL FUND MANAGEMENT S.A. 0.28% of their portfolio | 204.1k $25.5m | New |
| TWO SIGMA INVESTMENTS, LP 0.06% of their portfolio | 202.3k $25.3m | Reduced -339.5k |
| Simplify Asset Management Inc. 1.66% of their portfolio | 193.0k $24.1m | Added +88.5k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 185.6k $23.1m | Added +7.7k |
| Altium Capital Management LLC 6.33% of their portfolio | 170.0k $21.2m | Added +88.1k |
| Swiss National Bank 0.01% of their portfolio | 166.1k $20.7m | Unchanged |
| HSBC HOLDINGS PLC 0.01% of their portfolio | 158.6k $19.9m | Added +156.3k |
| California Public Employees Retirement System 0.01% of their portfolio | 150.5k $18.8m | Reduced -1.3k |
| Logos Global Management LP 2.10% of their portfolio | 150.0k $18.7m | Reduced -150.0k |
| Legal & General Group Plc 0.00% of their portfolio | 142.9k $17.8m | Added +3.7k |
| TD Asset Management Inc 0.02% of their portfolio | 142.4k $17.7m | Reduced -16.7k |
| C WorldWide Group Holding A/S 0.18% of their portfolio | 140.3k $17.5m | Unchanged |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 0.78% of their portfolio | 138.1k $17.2m | Added +116.8k |
| Rafferty Asset Management, LLC 0.06% of their portfolio | 138.0k $17.2m | Reduced -8.5k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.02% of their portfolio | 136.4k $17.0m | Reduced -22.1k |
| Finepoint Capital LP 2.03% of their portfolio | 133.5k $16.7m | Added +700 |
| TWO SIGMA ADVISERS, LP 0.04% of their portfolio | 128.0k $16.0m | Reduced -478.8k |
| SPHERA FUNDS MANAGEMENT LTD. 2.57% of their portfolio | 125.8k $15.7m | Added +42.2k |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 125.1k $15.6m | Added +3.3k |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 120.7k $15.1m | Added +32.3k |
| Ghost Tree Capital, LLC 5.43% of their portfolio | 120.0k $15.0m | Added +65.0k |
| Retirement Systems of Alabama 0.05% of their portfolio | 115.8k $14.5m | Reduced -821 |
| Corebridge Financial, Inc. 0.08% of their portfolio | 113.8k $14.2m | Reduced -6.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 111.4k $13.9m | Added +3.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.02% of their portfolio | 110.2k $13.8m | Reduced -84.6k |
| Twin Tree Management, LP 0.31% of their portfolio | 107.5k $13.4m | New |
| BRAUN STACEY ASSOCIATES INC 0.49% of their portfolio | 103.0k $12.9m | Added +4.8k |
| J. Goldman & Co LP 0.54% of their portfolio | 99.2k $12.4m | Added +55.6k |
| PINNACLE ASSOCIATES LTD 0.15% of their portfolio | 92.0k $8.9m | Added +41.8k |
| PFM Health Sciences, LP 0.63% of their portfolio | 88.2k $11.0m | Unchanged |
| 683 Capital Management, LLC 1.11% of their portfolio | 87.2k $10.9m | Added +23.7k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.02% of their portfolio | 84.2k $10.5m | Reduced -1.6k |