SAREPTA THERAPEUTICS INC SRPT
COM · Common Stock · CUSIP 803607100 · ISIN US8036071004
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, MA
- Founded1980
- Websitesarepta.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($7.1m this quarter). Holder counts are more reliable. Shares outstanding: 93.5m as of 2023-10-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $96.55. Options: 34 managers hold calls ($715.7m notional), 32 hold puts ($383.4m).
Trends to Q4 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 376 |
| Q4 2022 | 414 |
| Q1 2023 | 427 |
| Q2 2023 | 406 |
| Q3 2023 | 396 |
| Q4 2023 | 397 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 199 | 169 |
| Q1 2023 | 219 | 183 |
| Q2 2023 | 204 | 205 |
| Q3 2023 | 201 | 180 |
| Q4 2023 | 181 | 206 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2023 | $489.0m | $467.1m | 0.96 |
| Q2 2023 | $276.3m | $402.2m | 1.46 |
| Q3 2023 | $655.9m | $524.1m | 0.80 |
| Q4 2023 | $715.7m | $383.4m | 0.54 |
Biggest buyers
| Capital International Investors | Added | +2.9m |
| MORGAN STANLEY | Added | +1.9m |
| EcoR1 Capital, LLC | New | +832.9k |
| BANK OF AMERICA CORP /DE/ | Added | +684.5k |
| BANK OF NOVA SCOTIA | New | +528.8k |
| Deep Track Capital, LP | New | +500.0k |
| STATE STREET CORP | Added | +413.5k |
| DEUTSCHE BANK AG\ | Added | +403.8k |
| ROYAL BANK OF CANADA | Added | +365.2k |
| Avoro Capital Advisors LLC | Added | +319.4k |
Biggest sellers
| JPMORGAN CHASE & CO | Reduced | -2.0m |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Sold out | -806.4k |
| AMERICAN CENTURY COMPANIES INC | Reduced | -584.2k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -560.0k |
| GOLDMAN SACHS GROUP INC | Reduced | -558.0k |
| Capital Research Global Investors | Sold out | -557.5k |
| AMERIPRISE FINANCIAL INC | Reduced | -522.2k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -508.1k |
| LORD, ABBETT & CO. LLC | Sold out | -483.2k |
| Avidity Partners Management LP | Sold out | -450.0k |
Biggest calls
| JPMORGAN CHASE & CO | Added | $122.1m1.3m shares |
| Caption Management, LLC | Added | $93.0m964.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $86.9m900.8k shares |
| Logos Global Management LP | New | $67.5m700.0k shares |
| Portman Square Capital LLP | New | $52.9m548.3k shares |
| SIMPLEX TRADING, LLC | Added | $51.3m531.7k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $45.8m474.9k shares |
| CITADEL ADVISORS LLC | Reduced | $38.3m396.8k shares |
| GROUP ONE TRADING LLC | Added | $32.0m332.1k shares |
| JANE STREET GROUP, LLC | Added | $24.7m256.6k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $72.3m749.8k shares |
| CITADEL ADVISORS LLC | Added | $50.6m524.4k shares |
| JPMORGAN CHASE & CO | Added | $41.9m434.8k shares |
| SIMPLEX TRADING, LLC | Reduced | $29.0m301.2k shares |
| GROUP ONE TRADING LLC | Reduced | $28.8m298.4k shares |
| LMR Partners LLP | Reduced | $22.7m235.0k shares |
| JANE STREET GROUP, LLC | Added | $19.6m203.0k shares |
| GTS SECURITIES LLC | Added | $17.5m181.7k shares |
| Caption Management, LLC | Reduced | $16.3m169.1k shares |
| Sio Capital Management, LLC | New | $13.6m141.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +3.2 pts · filed 2026-07-30 | 15.8% |
| STATE STREET CORP 13G · institution +3.0 pts · filed 2026-08-07 | 8.4% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.6 pts · filed 2026-07-31 | 8.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.1% |
| AQR CAPITAL MANAGEMENT LLC 13G · institution -2.7 pts · filed 2026-08-13 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), D. E. SHAW & CO, L.P. (1.9%, 2025-11-14)
Insider purchases and sales in Q4 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 1 | $11.0m | 0 | — | — |
| Q4 2022 | 0 | — | 1 | $94.3k | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 1 | $7.4m | 1 | $1.6m | — |
| Q4 2023 | 2 | $5.9m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-11-03 | Barry Richard Director · By Trust | Bought | $3.2m40.0k shares |
| 2023-11-03 | INGRAM DOUGLAS S President & CEO, director | Bought | $2.0m25.2k shares |
| 2023-11-03 | Barry Richard Director · By LLC | Bought | $788.1k10.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2023
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.02% of their portfolio | 8.8m $850.1m | Added +243.2k |
| BlackRock Inc. 0.02% of their portfolio | 6.2m $599.0m | Added +178.1k |
| JANUS HENDERSON GROUP PLC 0.31% of their portfolio | 5.3m $515.5m | Reduced -436.7k |
| Capital International Investors 0.10% of their portfolio | 4.7m $457.2m | Added +2.9m |
| Avoro Capital Advisors LLC 5.79% of their portfolio | 4.3m $418.9m | Added +319.4k |
| WELLINGTON MANAGEMENT GROUP LLP 0.07% of their portfolio | 4.1m $398.0m | Added +217.8k |
| MORGAN STANLEY 0.01% of their portfolio | 2.8m $266.2m | Added +1.9m |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 2.6m $251.2m | Reduced -2.0m |
| STATE STREET CORP 0.01% of their portfolio | 2.4m $231.3m | Added +413.5k |
| Bank of New York Mellon Corp 0.05% of their portfolio | 2.3m $224.6m | Reduced -181.8k |
| T. Rowe Price Investment Management, Inc. 0.12% of their portfolio | 1.9m $185.1m | Added +24.4k |
| FMR LLC 0.01% of their portfolio | 1.5m $145.3m | Reduced -404.2k |
| DEUTSCHE BANK AG\ 0.07% of their portfolio | 1.5m $142.2m | Added +403.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 1.5m $141.7m | Added +60.8k |
| CITADEL ADVISORS LLC 0.13% of their portfolio | 1.3m $129.5m | Added +114.8k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 1.2m $116.9m | Added +684.5k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.73% of their portfolio | 1.2m $116.7m | Reduced -165.1k |
| Pictet Asset Management Holding SA 0.12% of their portfolio | 1.1m $105.3m | Added +126.7k |
| Casdin Capital, LLC 9.57% of their portfolio | 1.0m $97.1m | Reduced -3.8k |
| NORGES BANK 0.01% of their portfolio | 836.8k $80.7m | Added +23.9k |
| EcoR1 Capital, LLC 2.09% of their portfolio | 832.9k $80.3m | New |
| Thrivent Financial for Lutherans 0.17% of their portfolio | 828.7k $79.9m | Added +197.7k |
| ROYAL BANK OF CANADA 0.02% of their portfolio | 814.0k $78.5m | Added +365.2k |
| Camber Capital Management LP 2.70% of their portfolio | 800.0k $77.1m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 739.7k $71.3m | Reduced -48.2k |
| FEDERATED HERMES, INC. 0.17% of their portfolio | 708.4k $68.3m | Reduced -254.7k |
| TWO SIGMA ADVISERS, LP 0.16% of their portfolio | 706.1k $68.1m | Reduced -314.8k |
| Erste Asset Management GmbH 0.99% of their portfolio | 701.4k $67.7m | Added +16.0k |
| ORBIMED ADVISORS LLC 1.35% of their portfolio | 697.5k $67.3m | Added +168.3k |
| Boxer Capital, LLC 3.12% of their portfolio | 650.0k $62.7m | Added +50.0k |
| MILLENNIUM MANAGEMENT LLC 0.06% of their portfolio | 644.1k $62.1m | Added +294.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 576.4k $55.6m | Added +16.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.08% of their portfolio | 563.0k $54.3m | Reduced -119.9k |
| Nuveen Asset Management, LLC 0.02% of their portfolio | 533.3k $51.4m | Reduced -28.3k |
| BANK OF NOVA SCOTIA 0.10% of their portfolio | 528.8k $51.0m | New |
| Deep Track Capital, LP 1.69% of their portfolio | 500.0k $48.2m | New |
| Balyasny Asset Management L.P. 0.13% of their portfolio | 498.8k $48.1m | Added +278.4k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.22% of their portfolio | 459.1k $44.3m | Added +61.6k |
| PERCEPTIVE ADVISORS LLC 0.97% of their portfolio | 451.9k $43.6m | Added +269.2k |
| BARCLAYS PLC 0.02% of their portfolio | 442.9k $42.7m | Reduced -74.4k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 437.6k $42.2m | Added +12.1k |
| FIRST TRUST ADVISORS LP 0.05% of their portfolio | 432.4k $41.7m | Added +1.4k |
| Amundi 0.02% of their portfolio | 399.4k $47.8m | Added +91.9k |
| Assenagon Asset Management S.A. 0.11% of their portfolio | 383.8k $37.0m | Reduced -44.6k |
| ALKEON CAPITAL MANAGEMENT LLC 0.23% of their portfolio | 358.8k $34.6m | Reduced -100.0k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.14% of their portfolio | 358.5k $34.6m | Added +260.6k |
| D. E. Shaw & Co., Inc. 0.05% of their portfolio | 355.5k $34.3m | Added +263.4k |
| Fiera Capital Corp 0.10% of their portfolio | 348.2k $33.6m | Reduced -8.1k |
| Rock Springs Capital Management LP 0.78% of their portfolio | 327.6k $31.6m | Reduced -64.4k |
| MIZUHO MARKETS AMERICAS LLC 0.89% of their portfolio | 305.6k $29.5m | Added +59.7k |
| TWO SIGMA INVESTMENTS, LP 0.07% of their portfolio | 302.3k $29.2m | Reduced -508.1k |
| VOYA INVESTMENT MANAGEMENT LLC 0.03% of their portfolio | 301.8k $29.1m | Added +100.5k |
| UBS Group AG 0.01% of their portfolio | 276.3k $26.6m | Added +48.4k |
| Allspring Global Investments Holdings, LLC 0.04% of their portfolio | 273.7k $26.4m | Reduced -80.8k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 255.9k $24.7m | Reduced -217.7k |
| Bellevue Group AG 0.35% of their portfolio | 237.3k $22.9m | Reduced -4.5k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 231.0k $22.3m | Reduced -522.2k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 224.2k $21.6m | Added +20.9k |
| EAGLE ASSET MANAGEMENT INC 0.11% of their portfolio | 216.2k $20.8m | Reduced -2.1k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 214.3k $20.7m | Reduced -1.5k |
| TD Asset Management Inc 0.02% of their portfolio | 207.1k $20.0m | Added +2.5k |
| First Turn Management, LLC 2.82% of their portfolio | 203.9k $19.7m | First filing |
| Palo Alto Investors LP 1.75% of their portfolio | 200.9k $19.4m | Added +106.9k |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 194.4k $18.7m | Reduced -3.2k |
| Eagle Health Investments LP 3.71% of their portfolio | 189.4k $18.3m | Added +15.1k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 184.9k $17.8m | Reduced -558.0k |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 182.6k $17.6m | Added +98.3k |
| Candriam S.C.A. 0.12% of their portfolio | 182.4k $17.6m | Added +46.7k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.02% of their portfolio | 171.6k $16.5m | Reduced -2.2k |
| CREDIT SUISSE AG/ 0.02% of their portfolio | 167.7k $16.2m | Added +27.8k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 161.0k $15.5m | Reduced -170 |
| Swiss National Bank 0.01% of their portfolio | 156.3k $15.1m | Reduced -17.8k |
| TOBAM 1.32% of their portfolio | 156.0k $15.0m | Added +7.1k |
| TWINBEECH CAPITAL LP 0.24% of their portfolio | 154.8k $14.9m | New |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 152.6k $14.9m | Reduced -119.7k |
| Clearbridge Investments, LLC 0.01% of their portfolio | 151.1k $14.6m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.03% of their portfolio | 148.4k $14.3m | Added +118.2k |
| Aberdeen Group plc 0.03% of their portfolio | 146.8k $14.2m | New |
| Finepoint Capital LP 4.85% of their portfolio | 145.4k $14.0m | Unchanged |
| C WorldWide Group Holding A/S 0.18% of their portfolio | 140.3k $13.5m | Unchanged |
| GROUP ONE TRADING LLC 0.41% of their portfolio | 135.2k $13.0m | Reduced -27.6k |
| Ikarian Capital, LLC 3.50% of their portfolio | 132.6k $12.8m | New |
| California Public Employees Retirement System 0.01% of their portfolio | 126.4k $12.2m | Reduced -38.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.02% of their portfolio | 125.6k $12.1m | Reduced -14.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 124.2k $12.0m | Reduced -65.5k |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 123.2k $11.9m | Reduced -7.3k |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 118.5k $11.4m | Reduced -4.4k |
| AXA S.A. 0.02% of their portfolio | 117.8k $11.4m | Added +57.5k |
| Walleye Capital LLC 0.15% of their portfolio | 108.8k $10.5m | Added +67.1k |
| Rafferty Asset Management, LLC 0.04% of their portfolio | 103.2k $9.9m | Added +29.0k |
| Ghost Tree Capital, LLC 5.55% of their portfolio | 100.0k $9.6m | Added +60.0k |
| Portman Square Capital LLP 1.64% of their portfolio | 97.9k $9.4m | Added +26.4k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.02% of their portfolio | 92.4k $8.9m | Added +321 |
| PINNACLE ASSOCIATES LTD 0.15% of their portfolio | 92.0k $8.9m | Reduced -212 |
| FRED ALGER MANAGEMENT, LLC 0.05% of their portfolio | 90.3k $8.7m | Added +24.7k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.14% of their portfolio | 89.2k $8.6m | Reduced -33.4k |
| Hudson Bay Capital Management LP 0.07% of their portfolio | 88.2k $8.5m | Reduced -1.8k |
| Legal & General Group Plc 0.00% of their portfolio | 88.1k $8.5m | Reduced -4.4k |
| 683 Capital Management, LLC 0.84% of their portfolio | 86.6k $8.4m | Added +66.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 85.5k $8.2m | Reduced -4.4k |