SAREPTA THERAPEUTICS INC SRPT
COM · Common Stock · CUSIP 803607100 · ISIN US8036071004
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, MA
- Founded1980
- Websitesarepta.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($10.8m this quarter). Holder counts are more reliable. Shares outstanding: 93.5m as of 2023-10-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $121.20. Options: 43 managers hold calls ($655.9m notional), 31 hold puts ($524.1m).
Trends to Q3 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 376 |
| Q4 2022 | 414 |
| Q1 2023 | 427 |
| Q2 2023 | 406 |
| Q3 2023 | 396 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 199 | 169 |
| Q1 2023 | 219 | 183 |
| Q2 2023 | 204 | 205 |
| Q3 2023 | 201 | 180 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2022 | $368.4m | $246.3m | 0.67 |
| Q1 2023 | $489.0m | $467.1m | 0.96 |
| Q2 2023 | $276.3m | $402.2m | 1.46 |
| Q3 2023 | $655.9m | $524.1m | 0.80 |
Biggest buyers
| T. Rowe Price Investment Management, Inc. | New | +1.9m |
| Capital International Investors | New | +1.8m |
| Thrivent Financial for Lutherans | Added | +572.5k |
| BlackRock Inc. | Added | +530.3k |
| Camber Capital Management LP | Added | +400.0k |
| CITADEL ADVISORS LLC | Added | +337.3k |
| JANUS HENDERSON GROUP PLC | Added | +334.8k |
| MIZUHO MARKETS AMERICAS LLC | New | +245.9k |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Added | +230.6k |
| Balyasny Asset Management L.P. | New | +220.4k |
Biggest sellers
| EcoR1 Capital, LLC | Sold out | -3.7m |
| Avoro Capital Advisors LLC | Reduced | -602.9k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -478.7k |
| LORD, ABBETT & CO. LLC | Reduced | -322.0k |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | Reduced | -304.3k |
| Assenagon Asset Management S.A. | Reduced | -297.5k |
| TWO SIGMA ADVISERS, LP | Reduced | -238.5k |
| GOLDMAN SACHS GROUP INC | Reduced | -226.4k |
| Allspring Global Investments Holdings, LLC | Reduced | -188.4k |
| D. E. Shaw & Co., Inc. | Reduced | -182.8k |
Biggest calls
| JPMORGAN CHASE & CO | Added | $80.2m661.8k shares |
| Caption Management, LLC | Added | $79.5m656.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $63.6m524.3k shares |
| CITADEL ADVISORS LLC | Added | $50.0m412.1k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $41.6m343.5k shares |
| Holocene Advisors, LP | New | $39.4m324.9k shares |
| SIMPLEX TRADING, LLC | Added | $28.6m236.2k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $27.2m224.6k shares |
| Ikarian Capital, LLC | Reduced | $25.7m2.1k shares |
| JANE STREET GROUP, LLC | Added | $24.1m198.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $93.5m771.1k shares |
| Caption Management, LLC | Added | $48.1m396.5k shares |
| GROUP ONE TRADING LLC | Added | $45.7m376.6k shares |
| Ikarian Capital, LLC | Reduced | $44.5m3.7k shares |
| LMR Partners LLP | Added | $44.5m367.2k shares |
| SIMPLEX TRADING, LLC | Added | $40.1m330.6k shares |
| CITADEL ADVISORS LLC | Added | $37.6m310.0k shares |
| GTS SECURITIES LLC | New | $19.3m159.1k shares |
| Balyasny Asset Management L.P. | Unchanged | $16.4m135.4k shares |
| WOLVERINE ASSET MANAGEMENT LLC | Added | $16.0m132.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +3.2 pts · filed 2026-07-30 | 15.8% |
| STATE STREET CORP 13G · institution +3.0 pts · filed 2026-08-07 | 8.4% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.6 pts · filed 2026-07-31 | 8.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.1% |
| AQR CAPITAL MANAGEMENT LLC 13G · institution -2.7 pts · filed 2026-08-13 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), D. E. SHAW & CO, L.P. (1.9%, 2025-11-14)
Insider purchases and sales in Q3 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2021 | 2 | $2.3m | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 1 | $11.0m | 0 | — | — |
| Q4 2022 | 0 | — | 1 | $94.3k | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 1 | $7.4m | 1 | $1.6m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-08-14 | Chambers Michael Andrew Director · By Revocable Trust | Bought | $1.1m10.0k shares |
| 2023-08-11 | Chambers Michael Andrew Director · By Revocable Trust | Bought | $2.6m23.7k shares |
| 2023-08-10 | Chambers Michael Andrew Director · By Revocable Trust | Bought | $3.7m34.9k shares |
| 2023-08-04 | Wigzell Hans Lennart Rudolf Director | Sold | $1.6m15.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2023
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.03% of their portfolio | 8.6m $1.0bn | Added +41.5k |
| BlackRock Inc. 0.02% of their portfolio | 6.0m $731.4m | Added +530.3k |
| JANUS HENDERSON GROUP PLC 0.46% of their portfolio | 5.8m $700.9m | Added +334.8k |
| JPMORGAN CHASE & CO 0.07% of their portfolio | 4.6m $558.6m | Added +204.2k |
| Avoro Capital Advisors LLC 7.61% of their portfolio | 4.0m $487.9m | Reduced -602.9k |
| WELLINGTON MANAGEMENT GROUP LLP 0.09% of their portfolio | 3.9m $473.9m | Added +54.7k |
| Bank of New York Mellon Corp 0.07% of their portfolio | 2.5m $304.4m | Added +78.6k |
| STATE STREET CORP 0.01% of their portfolio | 2.0m $240.7m | Added +71.8k |
| FMR LLC 0.02% of their portfolio | 1.9m $231.7m | Added +107.4k |
| T. Rowe Price Investment Management, Inc. 0.16% of their portfolio | 1.9m $229.8m | New |
| Capital International Investors 0.06% of their portfolio | 1.8m $221.1m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.4m $170.8m | Added +20.7k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.94% of their portfolio | 1.4m $166.7m | Added +170.0k |
| CITADEL ADVISORS LLC 0.16% of their portfolio | 1.2m $148.9m | Added +337.3k |
| DEUTSCHE BANK AG\ 0.08% of their portfolio | 1.1m $129.8m | Reduced -35.6k |
| TWO SIGMA ADVISERS, LP 0.32% of their portfolio | 1.0m $123.8m | Reduced -238.5k |
| Casdin Capital, LLC 13.66% of their portfolio | 1.0m $122.5m | Reduced -4.7k |
| Pictet Asset Management Holding SA 0.14% of their portfolio | 964.9k $117.0m | First filing |
| FEDERATED HERMES, INC. 0.31% of their portfolio | 963.0k $116.7m | Reduced -1.9k |
| MORGAN STANLEY 0.01% of their portfolio | 855.4k $103.7m | Reduced -120.9k |
| NORGES BANK 0.02% of their portfolio | 813.0k $98.5m | Reduced -17.7k |
| TWO SIGMA INVESTMENTS, LP 0.27% of their portfolio | 810.5k $98.2m | Reduced -478.7k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.67% of their portfolio | 806.4k $97.8m | Added +230.6k |
| Camber Capital Management LP 3.48% of their portfolio | 800.0k $97.0m | Added +400.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 788.0k $95.5m | Added +7.0k |
| AMERIPRISE FINANCIAL INC 0.03% of their portfolio | 753.2k $91.3m | Reduced -13.0k |
| GOLDMAN SACHS GROUP INC 0.02% of their portfolio | 742.9k $90.1m | Reduced -226.4k |
| Erste Asset Management GmbH 1.43% of their portfolio | 685.4k $83.2m | Reduced -35.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.14% of their portfolio | 682.9k $82.8m | Added +40.8k |
| Thrivent Financial for Lutherans 0.18% of their portfolio | 631.0k $76.5m | Added +572.5k |
| Boxer Capital, LLC 3.87% of their portfolio | 600.0k $72.7m | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.06% of their portfolio | 592.3k $71.8m | Reduced -1.0k |
| Nuveen Asset Management, LLC 0.02% of their portfolio | 561.6k $68.1m | Reduced -26.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 560.4k $67.9m | Added +6.3k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.15% of their portfolio | 560.0k $67.9m | Reduced -95.0k |
| Capital Research Global Investors 0.02% of their portfolio | 557.5k $67.6m | Added +78 |
| ORBIMED ADVISORS LLC 1.38% of their portfolio | 529.2k $64.1m | Reduced -124.8k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 527.8k $64.0m | Added +78.7k |
| BARCLAYS PLC 0.04% of their portfolio | 517.3k $62.7m | Added +118.8k |
| LORD, ABBETT & CO. LLC 0.11% of their portfolio | 483.2k $58.6m | Reduced -322.0k |
| ALLIANCEBERNSTEIN L.P. 0.02% of their portfolio | 473.7k $57.4m | Reduced -27.6k |
| ALKEON CAPITAL MANAGEMENT LLC 0.35% of their portfolio | 458.8k $55.6m | Reduced -50.0k |
| Avidity Partners Management LP 2.20% of their portfolio | 450.0k $54.5m | Added +152.5k |
| ROYAL BANK OF CANADA 0.02% of their portfolio | 448.8k $54.4m | Added +16.1k |
| Artisan Partners Limited Partnership 0.09% of their portfolio | 439.8k $53.3m | Reduced -1.1k |
| FIRST TRUST ADVISORS LP 0.06% of their portfolio | 431.0k $52.2m | Reduced -173.4k |
| Assenagon Asset Management S.A. 0.18% of their portfolio | 428.3k $51.9m | Reduced -297.5k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 425.4k $51.6m | Added +14.9k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.29% of their portfolio | 397.5k $48.2m | Reduced -48.1k |
| Rock Springs Capital Management LP 1.27% of their portfolio | 392.0k $47.5m | Reduced -33.0k |
| Fiera Capital Corp 0.14% of their portfolio | 356.3k $43.2m | Added +73.9k |
| Allspring Global Investments Holdings, LLC 0.08% of their portfolio | 354.5k $43.0m | Reduced -188.4k |
| MILLENNIUM MANAGEMENT LLC 0.04% of their portfolio | 349.4k $42.4m | Added +180.5k |
| Amundi 0.02% of their portfolio | 307.5k $36.3m | Added +2.0k |
| Point72 Asset Management, L.P. 0.13% of their portfolio | 307.3k $37.3m | Reduced -22.0k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 272.2k $32.5m | Added +174.3k |
| PFM Health Sciences, LP 1.45% of their portfolio | 251.0k $30.4m | Added +85.2k |
| SAMLYN CAPITAL, LLC 0.53% of their portfolio | 247.7k $30.0m | Added +53.3k |
| MIZUHO MARKETS AMERICAS LLC 1.11% of their portfolio | 245.9k $29.8m | New |
| MARSHALL WACE, LLP 0.06% of their portfolio | 245.9k $29.8m | Added +186.9k |
| Bellevue Group AG 0.47% of their portfolio | 241.8k $29.3m | Added +41.5k |
| UBS Group AG 0.01% of their portfolio | 227.9k $27.6m | Added +11.5k |
| Balyasny Asset Management L.P. 0.07% of their portfolio | 220.4k $26.7m | New |
| EAGLE ASSET MANAGEMENT INC 0.16% of their portfolio | 218.2k $26.5m | Added +341 |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 215.8k $26.2m | Reduced -441 |
| TD Asset Management Inc 0.03% of their portfolio | 204.6k $24.8m | Added +161.8k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 203.3k $24.6m | Added +20.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.03% of their portfolio | 201.3k $24.4m | Added +134.6k |
| Logos Global Management LP 3.46% of their portfolio | 200.0k $24.2m | Reduced -100.0k |
| Ensign Peak Advisors, Inc 0.05% of their portfolio | 197.6k $24.0m | Reduced -480 |
| WELLS FARGO & COMPANY/MN 0.01% of their portfolio | 189.7k $23.0m | Reduced -1.5k |
| Nicholas Investment Partners, LP 1.70% of their portfolio | 188.1k $22.8m | New |
| PERCEPTIVE ADVISORS LLC 0.74% of their portfolio | 182.7k $22.1m | Added +101.6k |
| Invesco Ltd. 0.01% of their portfolio | 174.7k $21.2m | Reduced -166.8k |
| Eagle Health Investments LP 4.65% of their portfolio | 174.2k $21.1m | Added +76.9k |
| Swiss National Bank 0.02% of their portfolio | 174.1k $21.1m | Added +11.3k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio | 173.8k $21.1m | Added +8.9k |
| GREAT POINT PARTNERS LLC 3.77% of their portfolio | 165.2k $20.0m | Added +41.6k |
| California Public Employees Retirement System 0.02% of their portfolio | 164.5k $19.9m | Reduced -3.6k |
| GROUP ONE TRADING LLC 0.78% of their portfolio | 162.8k $19.7m | Reduced -5.0k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 161.2k $19.5m | Added +4.5k |
| TOBAM 1.45% of their portfolio | 148.9k $18.1m | Added +42.2k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.03% of their portfolio | 145.7k $17.7m | Added +125.3k |
| Finepoint Capital LP 8.78% of their portfolio | 145.4k $17.6m | Added +19.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.03% of their portfolio | 140.3k $17.0m | Reduced -95.0k |
| C WorldWide Group Holding A/S 0.23% of their portfolio | 140.3k $17.0m | Unchanged |
| CREDIT SUISSE AG/ 0.02% of their portfolio | 139.9k $17.0m | Reduced -84.9k |
| JENNISON ASSOCIATES LLC 0.01% of their portfolio | 138.4k $16.8m | Added +1.1k |
| Candriam S.C.A. 0.12% of their portfolio | 135.7k $16.5m | Added +35.7k |
| Russell Investments Group, Ltd. 0.03% of their portfolio | 130.6k $15.8m | Reduced -5.0k |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 122.9k $14.9m | Reduced -1.0k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.27% of their portfolio | 122.6k $14.9m | Unchanged |
| Saturn V Capital Management LP 6.01% of their portfolio | 118.4k $14.4m | Added +64.4k |
| COMERICA BANK 0.07% of their portfolio | 103.3k $12.5m | New |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.06% of their portfolio | 98.0k $11.9m | Added +2 |
| VAN ECK ASSOCIATES CORP 0.03% of their portfolio | 96.5k $11.7m | Reduced -326 |
| SEI INVESTMENTS CO 0.02% of their portfolio | 96.4k $11.7m | Added +1.4k |
| Mirae Asset Global Investments Co., Ltd. 0.03% of their portfolio | 95.9k $11.6m | Added +4.8k |
| Palo Alto Investors LP 1.08% of their portfolio | 94.0k $11.4m | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 92.5k $11.2m | Added +1.4k |