SANGAMO THERAPEUTICS INC SGMOQ
COM · Common Stock · CUSIP 800677106 · ISIN US8006771062
American biotechnology company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersRichmond, CA
- Founded1995
- Websitesangamo.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 414.3m as of 2026-03-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $0.05. Options: 2 managers hold calls ($25.4k notional), 2 hold puts ($33.3k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 197 |
| Q4 2022 | 182 |
| Q1 2023 | 181 |
| Q2 2023 | 153 |
| Q3 2023 | 136 |
| Q4 2023 | 131 |
| Q1 2024 | 132 |
| Q2 2024 | 130 |
| Q3 2024 | 104 |
| Q4 2024 | 130 |
| Q1 2025 | 123 |
| Q2 2025 | 115 |
| Q3 2025 | 112 |
| Q4 2025 | 105 |
| Q1 2026 | 112 |
| Q2 2026 | 6 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 39 | 74 |
| Q4 2024 | 69 | 45 |
| Q1 2025 | 54 | 62 |
| Q2 2025 | 43 | 55 |
| Q3 2025 | 56 | 37 |
| Q4 2025 | 41 | 52 |
| Q1 2026 | 53 | 32 |
| Q2 2026 | 3 | 105 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $989.0k | $1.2m | 1.19 |
| Q4 2025 | $535.0k | $553.7k | 1.03 |
| Q1 2026 | $344.0k | $314.9k | 0.92 |
| Q2 2026 | $25.4k | $33.3k | 1.31 |
Biggest buyers
| SIMPLEX TRADING, LLC | New | +76.5k |
| Heritage Investment Group, Inc. | New | +10.0k |
| FLOW TRADERS U.S. LLC | Added | +34 |
Biggest sellers
| ARMISTICE CAPITAL, LLC | Sold out | -40.4m |
| VANGUARD CAPITAL MANAGEMENT LLC | Sold out | -12.7m |
| TWO SIGMA INVESTMENTS, LP | Sold out | -6.3m |
| Balyasny Asset Management L.P. | Sold out | -5.3m |
| GEODE CAPITAL MANAGEMENT, LLC | Sold out | -4.6m |
| BlackRock, Inc. | Sold out | -4.5m |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -3.8m |
| UBS Group AG | Sold out | -2.6m |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Sold out | -2.4m |
| VANGUARD FIDUCIARY TRUST CO | Sold out | -2.3m |
Biggest calls
| JANE STREET GROUP, LLC | Added | $19.7k365.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $5.7k105.3k shares |
Biggest puts
| SIMPLEX TRADING, LLC | Added | $20.2k373.2k shares |
| JANE STREET GROUP, LLC | Added | $13.2k244.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARMISTICE CAPITAL, LLC 13G · institution -0.4 pts · filed 2026-08-14 | 9.4% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 2 | $107.4k | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-04-22 | Davis Gregory D Head of Research & Technology | Sold | $17.5k69.8k shares |
| 2026-04-21 | Dubois-Stringfellow Nathalie SVP-CHIEF DEVELOPMENT OFFICER | Sold | $89.9k345.9k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.00% of their portfolio | 400.0k $22.0k | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 76.5k $4.1k | New |
| Axiom Investment Management LLC 0.00% of their portfolio | 25.4k $1.4k | Unchanged |
| FLOW TRADERS U.S. LLC 0.00% of their portfolio | 21.5k $1.0k | Added +34 |
| Heritage Investment Group, Inc. 0.00% of their portfolio | 10.0k $539 | New |
| BARCLAYS PLC 0.00% of their portfolio | 1 $0 | Unchanged |