REZOLUTE INC RZLT
COM NEW · Common Stock · CUSIP 76200L309
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersRedwood City, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.2m this quarter). Holder counts are more reliable. Shares outstanding: 90.8m as of 2025-09-15, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.40. Options: 9 managers hold calls ($10.4m notional), 4 hold puts ($705.8k).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 34 |
| Q4 2022 | 35 |
| Q1 2023 | 33 |
| Q2 2023 | 30 |
| Q3 2023 | 31 |
| Q4 2023 | 33 |
| Q1 2024 | 34 |
| Q2 2024 | 53 |
| Q3 2024 | 60 |
| Q4 2024 | 72 |
| Q1 2025 | 78 |
| Q2 2025 | 93 |
| Q3 2025 | 116 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 15 | 7 |
| Q1 2024 | 17 | 13 |
| Q2 2024 | 42 | 11 |
| Q3 2024 | 37 | 21 |
| Q4 2024 | 42 | 28 |
| Q1 2025 | 49 | 29 |
| Q2 2025 | 76 | 41 |
| Q3 2025 | 74 | 39 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $1.0m | $17.7k | 0.02 |
| Q1 2025 | $1.2m | $58.8k | 0.05 |
| Q2 2025 | $3.3m | $89.6k | 0.03 |
| Q3 2025 | $10.4m | $705.8k | 0.07 |
Biggest buyers
| Siren, L.L.C. | New | +4.9m |
| Balyasny Asset Management L.P. | New | +1.8m |
| STATE STREET CORP | Added | +1.3m |
| BANK OF AMERICA CORP /DE/ | Added | +1.2m |
| Point72 Asset Management, L.P. | Added | +945.9k |
| BlackRock, Inc. | Added | +922.9k |
| 22NW, LP | New | +820.7k |
| MANGROVE PARTNERS IM, LLC | Added | +584.7k |
| FRED ALGER MANAGEMENT, LLC | New | +557.4k |
| GOLDMAN SACHS GROUP INC | Added | +508.4k |
Biggest sellers
| Nantahala Capital Management, LLC | Sold out | -2.3m |
| Caligan Partners LP | Sold out | -1.5m |
| Woodline Partners LP | Reduced | -965.3k |
| GREAT POINT PARTNERS LLC | Reduced | -581.7k |
| Blackstone Inc. | Reduced | -536.4k |
| SPHERA FUNDS MANAGEMENT LTD. | Reduced | -387.5k |
| UBS Group AG | Reduced | -341.2k |
| BOOTHBAY FUND MANAGEMENT, LLC | Sold out | -266.7k |
| J. Goldman & Co LP | Reduced | -191.7k |
| Stonepine Capital Management, LLC | Reduced | -179.0k |
Biggest calls
| Caption Management, LLC | Added | $4.1m435.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.6m276.1k shares |
| Hudson Bay Capital Management LP | Unchanged | $1.2m125.0k shares |
| Centiva Capital, LP | New | $753.9k80.2k shares |
| Rosalind Advisors, Inc. | New | $546.4k263.1k shares |
| DLD Asset Management, LP | New | $469.8k50.0k shares |
| SIMPLEX TRADING, LLC | Added | $382.0k40.7k shares |
| CITADEL ADVISORS LLC | Added | $374.1k39.8k shares |
| GROUP ONE TRADING LLC | New | $14.1k1.5k shares |
Biggest puts
| JANE STREET GROUP, LLC | New | $296.1k31.5k shares |
| CITADEL ADVISORS LLC | Added | $241.6k25.7k shares |
| SIMPLEX TRADING, LLC | Added | $154.0k16.4k shares |
| GROUP ONE TRADING LLC | Added | $14.1k1.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2025-12-18 | 9.9% |
| Opaleye Management Inc. 13G · passive investor +1.3 pts · filed 2026-05-11 | 6.6% |
| Dellora Investments LP 13G · passive investor new · filed 2026-08-12 | 5.9% |
| JENNISON ASSOCIATES LLC 13G · institution new · filed 2026-10-28 | 5.5% |
| BlackRock, Inc. 13G · institution new · filed 2025-10-17 | 5.4% |
Fell to 5% or below in the last year: BALYASNY ASSET MANAGEMENT L.P. (4.8%, 2026-08-14), BANK OF AMERICA CORP /DE/ (1.2%, 2026-08-12), VANGUARD GROUP INC (0.0%, 2026-03-26), Invus Global Management, LLC (0.0%, 2026-02-13), FMR LLC (2.5%, 2026-01-08)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 4 | $318.9k | 0 | — | — |
| Q2 2024 | 4 | $5.2m | 0 | — | — |
| Q3 2024 | 1 | $20.0k | 0 | — | — |
| Q4 2024 | 1 | $84.3k | 0 | — | — |
| Q1 2025 | 3 | $159.5k | 0 | — | — |
| Q2 2025 | 4 | $4.0m | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
None reported in Q3 2025.
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| FEDERATED HERMES, INC. 0.23% of their portfolio | 14.0m $131.9m | Unchanged |
| FMR LLC 0.01% of their portfolio | 12.8m $120.0m | Reduced -47.6k |
| BlackRock, Inc. 0.00% of their portfolio | 5.0m $47.0m | Added +922.9k |
| Siren, L.L.C. 1.79% of their portfolio | 4.9m $45.8m | New |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.4m $41.5m | Added +387.5k |
| Blackstone Inc. 0.12% of their portfolio | 3.0m $28.4m | Reduced -536.4k |
| MANGROVE PARTNERS IM, LLC 2.00% of their portfolio | 2.9m $27.1m | Added +584.7k |
| MARSHALL WACE, LLP 0.03% of their portfolio | 2.7m $25.6m | Reduced -158.2k |
| UBS Group AG 0.00% of their portfolio | 2.7m $25.3m | Reduced -341.2k |
| GREAT POINT PARTNERS LLC 9.62% of their portfolio | 2.5m $23.0m | Reduced -581.7k |
| Vivo Capital, LLC 1.60% of their portfolio | 2.1m $19.9m | Unchanged |
| Affinity Asset Advisors, LLC 1.84% of their portfolio | 2.1m $19.7m | Reduced -100.0k |
| STATE STREET CORP 0.00% of their portfolio | 2.1m $19.7m | Added +1.3m |
| Integral Health Asset Management, LLC 1.37% of their portfolio | 2.0m $18.8m | Added +200.0k |
| CAXTON CORP 81.70% of their portfolio | 2.0m $18.7m | Added +382.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.8m $17.4m | Added +136.3k |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 1.8m $17.1m | New |
| Rosalind Advisors, Inc. 6.00% of their portfolio | 1.8m $17.0m | Added +66.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.3m $12.1m | Added +1.2m |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 1.2m $10.9m | Added +945.9k |
| Woodline Partners LP 0.04% of their portfolio | 938.8k $8.8m | Reduced -965.3k |
| STEMPOINT CAPITAL LP 1.74% of their portfolio | 917.6k $8.6m | Added +273.0k |
| Opaleye Management Inc. 1.20% of their portfolio | 903.4k $8.5m | Unchanged |
| 22NW, LP 3.63% of their portfolio | 820.7k $7.7m | New |
| ADAR1 Capital Management, LLC 0.76% of their portfolio | 816.0k $7.7m | Reduced -173.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 772.5k $7.3m | Added +180.6k |
| Velan Capital Investment Management LP 6.62% of their portfolio | 750.0k $7.0m | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 652.1k $6.1m | Added +448.6k |
| FRED ALGER MANAGEMENT, LLC 0.02% of their portfolio | 557.4k $5.2m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 541.5k $5.1m | Added +508.4k |
| PFM Health Sciences, LP 0.36% of their portfolio | 452.7k $4.3m | Added +18.6k |
| SPHERA FUNDS MANAGEMENT LTD. 0.81% of their portfolio | 363.9k $3.4m | Reduced -387.5k |
| Invesco Ltd. 0.00% of their portfolio | 359.9k $3.4m | Added +321.5k |
| MORGAN STANLEY 0.00% of their portfolio | 337.9k $3.2m | Added +100.8k |
| BARCLAYS PLC 0.00% of their portfolio | 309.7k $2.9m | Reduced -88.8k |
| Nuveen, LLC 0.00% of their portfolio | 308.3k $2.9m | Added +135.4k |
| J. Goldman & Co LP 0.10% of their portfolio | 294.3k $2.8m | Reduced -191.7k |
| Knott David M Jr 1.08% of their portfolio | 275.0k $2.6m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 251.6k $2.4m | Reduced -9.8k |
| Driehaus Capital Management LLC 0.02% of their portfolio | 233.0k $2.2m | Unchanged |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 227.5k $2.1m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 191.3k $1.8m | Added +50.5k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 179.3k $1.7m | New |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 166.1k $1.6m | New |
| Point72 Europe (London) LLP 0.07% of their portfolio | 127.7k $1.2m | Added +89.2k |
| Campbell & CO Investment Adviser LLC 0.09% of their portfolio | 120.3k $1.1m | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 109.8k $1.0m | Added +23.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 105.2k $988.7k | Added +8.2k |
| CANTOR FITZGERALD, L. P. 0.02% of their portfolio | 100.0k $940.0k | Reduced -20.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 98.5k $925.8k | Reduced -122.4k |
| Caption Management, LLC 0.05% of their portfolio | 86.8k $815.9k | Reduced -13.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 85.8k $806.6k | Added +69.2k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 69.1k $649.8k | Added +63.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 66.4k $624.2k | Added +34.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 63.3k $595.2k | Reduced -18.1k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 62.3k $586.0k | Reduced -9.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 60.8k $571.5k | Added +12.2k |
| Decheng Capital LLC 0.10% of their portfolio | 59.9k $563.1k | Unchanged |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 59.0k $554.6k | New |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 52.9k $497.1k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 49.1k $461.9k | Added +13.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 43.9k $412.4k | Added +19.7k |
| ALPS ADVISORS INC 0.00% of their portfolio | 42.9k $403.2k | Reduced -3.2k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 42.2k $397.0k | Unchanged |
| Pale Fire Capital SE 0.04% of their portfolio | 41.9k $394.1k | Reduced -7.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 41.5k $390.0k | Added +7.9k |
| Stonepine Capital Management, LLC 0.31% of their portfolio | 40.0k $376.0k | Reduced -179.0k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 38.7k $363.1k | Added +2.0k |
| Verition Fund Management LLC 0.00% of their portfolio | 34.8k $327.0k | New |
| ALTFEST L J & CO INC 0.03% of their portfolio | 32.0k $301.1k | New |
| Jain Global LLC 0.00% of their portfolio | 31.7k $297.8k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 30.0k $281.6k | Reduced -12.1k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 29.2k $274.3k | New |
| Massar Capital Management, LP 0.09% of their portfolio | 28.2k $264.7k | Unchanged |
| AlphaQuest LLC 0.02% of their portfolio | 26.8k $251.5k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 26.4k $248.3k | Added +2.7k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 26.2k $246.5k | Reduced -6.6k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 24.6k $231.2k | Added +1.3k |
| XTX Topco Ltd 0.01% of their portfolio | 24.3k $228.8k | Reduced -2.0k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 21.8k $204.9k | Added +6.5k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 21.7k $203.0k | Added +13.1k |
| Trexquant Investment LP 0.00% of their portfolio | 20.6k $193.8k | New |
| Tidal Investments LLC 0.00% of their portfolio | 19.4k $182.4k | New |
| Huntleigh Advisors, Inc. 0.03% of their portfolio | 17.5k $164.5k | Added +2.5k |
| EHP Funds Inc. 0.17% of their portfolio | 14.0k $131.8k | New |
| MML INVESTORS SERVICES, LLC 0.00% of their portfolio | 13.9k $130.8k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 13.2k $124.3k | Reduced -499 |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 13.2k $123.9k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 12.8k $120.1k | Reduced -6.2k |
| PROFUND ADVISORS LLC 0.00% of their portfolio | 12.3k $115.9k | New |
| NIA IMPACT ADVISORS, LLC 0.03% of their portfolio | 11.5k $107.7k | New |
| WEXFORD CAPITAL LP 0.03% of their portfolio | 10.9k $102.3k | Reduced -27.5k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 10.8k $101.4k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 10.0k $94.0k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 8.3k $78.3k | Added +4.1k |
| Legal & General Group Plc 0.00% of their portfolio | 8.2k $77.2k | Added +948 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 6.8k $64.2k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 6.5k $61.3k | New |
| NewEdge Advisors, LLC 0.00% of their portfolio | 3.8k $35.2k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 3.4k $31.6k | Reduced -20.3k |