REPLIMUNE GROUP INC REPL
COM · Common Stock · CUSIP 76029N106
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersWoburn, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($281.1k this quarter). Holder counts are more reliable. Shares outstanding: 78.1m as of 2025-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.29. Options: 13 managers hold calls ($20.5m notional), 11 hold puts ($27.4m).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 106 |
| Q4 2022 | 136 |
| Q1 2023 | 141 |
| Q2 2023 | 142 |
| Q3 2023 | 128 |
| Q4 2023 | 141 |
| Q1 2024 | 151 |
| Q2 2024 | 150 |
| Q3 2024 | 145 |
| Q4 2024 | 158 |
| Q1 2025 | 168 |
| Q2 2025 | 176 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 60 | 65 |
| Q4 2023 | 90 | 61 |
| Q1 2024 | 87 | 55 |
| Q2 2024 | 86 | 72 |
| Q3 2024 | 75 | 68 |
| Q4 2024 | 89 | 53 |
| Q1 2025 | 86 | 62 |
| Q2 2025 | 82 | 88 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $287.8k | $1.0m | 3.48 |
| Q4 2024 | $536.1k | $528.0k | 0.98 |
| Q1 2025 | $716.4k | $2.6m | 3.68 |
| Q2 2025 | $20.5m | $27.4m | 1.34 |
Biggest buyers
| Point72 Asset Management, L.P. | Added | +616.6k |
| Ally Bridge Group (NY) LLC | New | +528.5k |
| NAN FUNG TRINITY (HK) LTD | New | +465.5k |
| GOLDMAN SACHS GROUP INC | Added | +427.2k |
| Boxer Capital Management, LLC | Added | +415.0k |
| TANG CAPITAL MANAGEMENT LLC | Added | +300.0k |
| CITADEL ADVISORS LLC | Added | +254.7k |
| SECTORAL ASSET MANAGEMENT INC | New | +231.7k |
| BARCLAYS PLC | Added | +217.3k |
| DIMENSIONAL FUND ADVISORS LP | Added | +215.6k |
Biggest sellers
| BRAIDWELL LP | Reduced | -1.0m |
| Sofinnova Investments, Inc. | Reduced | -673.4k |
| MARSHALL WACE, LLP | Reduced | -621.2k |
| Nuveen, LLC | Reduced | -544.1k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -429.2k |
| VANGUARD GROUP INC | Reduced | -363.3k |
| Nan Fung Group Holdings Ltd | Reduced | -350.5k |
| BlackRock, Inc. | Reduced | -331.5k |
| D. E. Shaw & Co., Inc. | Reduced | -290.0k |
| Redmile Group, LLC | Reduced | -233.7k |
Biggest calls
| Caption Management, LLC | Added | $7.4m792.4k shares |
| JANE STREET GROUP, LLC | New | $3.1m336.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.1m229.3k shares |
| SIMPLEX TRADING, LLC | Added | $2.0m213.8k shares |
| CITADEL ADVISORS LLC | Added | $1.5m161.6k shares |
| Centiva Capital, LP | New | $1.4m150.0k shares |
| BARCLAYS PLC | New | $705.1k75.9k shares |
| MILLENNIUM MANAGEMENT LLC | New | $696.8k75.0k shares |
| J. Goldman & Co LP | New | $628.0k67.6k shares |
| Rosalind Advisors, Inc. | New | $515.6k231.8k shares |
Biggest puts
| Sofinnova Investments, Inc. | New | $13.9m1.5m shares |
| Caption Management, LLC | New | $4.1m445.6k shares |
| MILLENNIUM MANAGEMENT LLC | New | $3.8m412.7k shares |
| CANTOR FITZGERALD, L. P. | New | $1.9m200.0k shares |
| CITADEL ADVISORS LLC | Added | $1.4m152.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.1m116.7k shares |
| SIMPLEX TRADING, LLC | Added | $886.0k95.4k shares |
| JANE STREET GROUP, LLC | New | $224.8k24.2k shares |
| LMR Partners LLP | New | $53.9k5.8k shares |
| GROUP ONE TRADING LLC | New | $22.3k2.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
BAKER BROS. ADVISORS LP
13D · may seek influence
-2.5 pts · filed 2026-08-11
Stated purposeItem 4 of Schedule 13D is supplemented and amended, as the case may be, as follows: The disclosures in Item 5 and Item 6 below are incorporated herein by reference. On August 9, 2026, Replimune Group, Inc. (the "Issuer") entered into an underwriting agreement (the "Underwriting Agreement") with Leerink Partners LLC, J.P. Morgan Securities LLC, and Cantor Fitzgerald & Co. (collectively, the "Underwriters"), related to the public offering (the "Offering") of 9,701,490 shares of common stock of the Issuer ("Common Stock") at a price to the public of $12.06 per share and 2,736,340 pre-funded warrants at a price to the public of $12.0599 per pre-funded warrant to purchase shares of Common Stock that are exercisable at any time on a 1-for-1 basis into Common Stock at an exercise price of $0.00… Full filing |
11.8% |
| RTW INVESTMENTS, LP 13G · institution +0.7 pts · filed 2026-05-15 | 8.9% |
| MONTANOVA CAPITAL, LLC 13G · passive investor +2.8 pts · filed 2026-08-06 | 7.9% |
| GOLDMAN SACHS GROUP INC 13G · institution new · filed 2026-08-10 | 5.3% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.3% |
Fell to 5% or below in the last year: Ridgeback Capital Investments L.P. (8.7%, 2026-08-14), PRICE T ROWE ASSOCIATES INC /MD/ (0.2%, 2026-05-07), Forbion Capital Fund III Cooperatief U.A. (3.5%, 2026-02-17), Redmile Group, LLC (0.7%, 2025-11-14), Point72 Asset Management, L.P. (4.7%, 2025-11-14)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 1 | $944.9k | $944.9k |
| Q4 2023 | 0 | — | 2 | $137.2k | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 7 | $753.7k | $119.1k |
| Q3 2024 | 0 | — | 1 | $91.0k | — |
| Q4 2024 | 0 | — | 3 | $258.4k | $124.2k |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 6 | $603.7k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-05-20 | Astley-Sparke Philip Director | Sold | $260.2k32.3k shares |
| 2025-05-20 | Patel Sushil Chief Executive Officer, director | Sold | $202.3k25.1k shares |
| 2025-05-20 | Xynos Konstantinos Chief Medical Officer | Sold | $64.1k8.0k shares |
| 2025-05-20 | Sarchi Christopher Chief Commercial Officer | Sold | $30.2k3.7k shares |
| 2025-05-20 | Schwendenman Andrew Chief Accounting Officer | Sold | $26.5k3.3k shares |
| 2025-05-20 | Hill Emily Luisa Chief Financial Officer | Sold | $20.4k2.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 1.00% of their portfolio | 11.0m $102.6m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 10.8m $100.5m | Reduced -34.6k |
| BlackRock, Inc. 0.00% of their portfolio | 5.7m $53.2m | Reduced -331.5k |
| Redmile Group, LLC 4.61% of their portfolio | 4.7m $43.3m | Reduced -233.7k |
| FCPM III SERVICES B.V. 9.84% of their portfolio | 3.9m $36.3m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.5m $32.2m | Reduced -363.3k |
| TANG CAPITAL MANAGEMENT LLC 1.50% of their portfolio | 3.2m $29.7m | Added +300.0k |
| STATE STREET CORP 0.00% of their portfolio | 2.5m $22.8m | Added +54.6k |
| Boxer Capital Management, LLC 10.34% of their portfolio | 2.2m $20.5m | Added +415.0k |
| RTW INVESTMENTS, LP 0.27% of their portfolio | 2.1m $19.2m | Unchanged |
| Omega Fund Management, LLC 11.88% of their portfolio | 2.0m $18.3m | Unchanged |
| MARSHALL WACE, LLP 0.02% of their portfolio | 1.9m $17.3m | Reduced -621.2k |
| Sofinnova Investments, Inc. 1.14% of their portfolio | 1.8m $16.8m | Reduced -673.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.6m $15.1m | Reduced -48.7k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.2m $10.8m | Added +215.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.1m $10.4m | Added +427.2k |
| MPM BIOIMPACT LLC 1.58% of their portfolio | 983.8k $9.1m | Reduced -3.3k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 944.5k $8.8m | Added +8.1k |
| MORGAN STANLEY 0.00% of their portfolio | 921.7k $8.6m | Reduced -6.6k |
| Rosalind Advisors, Inc. 4.05% of their portfolio | 900.0k $8.4m | Added +50.0k |
| Parkman Healthcare Partners LLC 0.96% of their portfolio | 896.7k $8.3m | Reduced -53.7k |
| Woodline Partners LP 0.04% of their portfolio | 856.0k $8.0m | Added +750 |
| EcoR1 Capital, LLC 0.47% of their portfolio | 850.3k $7.9m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 794.1k $7.4m | Reduced -429.2k |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 712.5k $6.6m | Added +616.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 586.8k $5.5m | Reduced -46.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 553.2k $5.1m | Added +1.1k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 533.0k $5.0m | Reduced -30.7k |
| Ally Bridge Group (NY) LLC 4.29% of their portfolio | 528.5k $4.9m | New |
| Artisan Partners Limited Partnership 0.01% of their portfolio | 511.4k $4.8m | Reduced -53.7k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 506.6k $4.7m | Reduced -290.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 505.1k $4.7m | Added +143.8k |
| NAN FUNG TRINITY (HK) LTD 0.52% of their portfolio | 465.5k $4.3m | New |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 432.7k $4.0m | Added +99.4k |
| BRAIDWELL LP 0.13% of their portfolio | 422.9k $3.9m | Reduced -1.0m |
| Exome Asset Management LLC 3.14% of their portfolio | 397.8k $3.7m | Added +103.0k |
| FMR LLC 0.00% of their portfolio | 391.7k $3.6m | Reduced -11.7k |
| BARCLAYS PLC 0.00% of their portfolio | 372.1k $3.5m | Added +217.3k |
| Catalio Capital Management, LP 0.64% of their portfolio | 330.3k $3.1m | Reduced -25.3k |
| TD Asset Management Inc 0.00% of their portfolio | 327.5k $3.0m | Added +51.6k |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 322.4k $3.0m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 277.5k $2.6m | Added +254.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 269.1k $2.5m | Added +61.0k |
| UBS Group AG 0.00% of their portfolio | 243.4k $2.3m | Added +95.1k |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 234.8k $2.2m | Reduced -223.9k |
| SECTORAL ASSET MANAGEMENT INC 1.42% of their portfolio | 231.7k $2.2m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 206.6k $1.9m | Added +17.4k |
| Moody Aldrich Partners LLC 0.35% of their portfolio | 194.5k $1.8m | Reduced -2.9k |
| READYSTATE ASSET MANAGEMENT LP 0.07% of their portfolio | 187.7k $1.7m | New |
| Velan Capital Investment Management LP 1.70% of their portfolio | 183.1k $1.7m | Added +1.0k |
| Candriam S.C.A. 0.01% of their portfolio | 171.5k $1.6m | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 168.0k $1.6m | Added +9.7k |
| ExodusPoint Capital Management, LP 0.02% of their portfolio | 157.6k $1.5m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 154.2k $1.4m | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 153.1k $1.4m | Reduced -3.1k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 136.0k $1.3m | Added +130.7k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 133.1k $1.2m | Reduced -132 |
| Trexquant Investment LP 0.01% of their portfolio | 131.5k $1.2m | Reduced -21.1k |
| Saturn V Capital Management LP 0.49% of their portfolio | 128.9k $1.2m | New |
| Nuveen, LLC 0.00% of their portfolio | 127.3k $1.2m | Reduced -544.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 126.4k $1.2m | Added +39.6k |
| CANTOR FITZGERALD, L. P. 0.03% of their portfolio | 125.7k $1.2m | Added +85.7k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.11% of their portfolio | 123.8k $1.1m | Added +41.2k |
| Invesco Ltd. 0.00% of their portfolio | 119.3k $1.1m | Reduced -203.0k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% of their portfolio | 114.1k $1.1m | Reduced -136.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 102.0k $947.6k | Added +6.6k |
| PANAGORA ASSET MANAGEMENT INC 0.00% of their portfolio | 100.7k $935.7k | Reduced -5.8k |
| HRT FINANCIAL LP 0.00% of their portfolio | 91.2k $847.0k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 87.8k $815.5k | Reduced -68.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 87.1k $809.6k | Reduced -177.8k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 81.9k $761.3k | Unchanged |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 79.5k $738.8k | Added +923 |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 79.4k $737.3k | Added +33.5k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 76.3k $709.2k | Added +1.2k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 74.8k $694.7k | Added +27.1k |
| Centiva Capital, LP 0.05% of their portfolio | 74.3k $689.8k | New |
| Swiss National Bank 0.00% of their portfolio | 73.5k $682.8k | Reduced -30.2k |
| SummitTX Capital, L.P. 0.03% of their portfolio | 69.2k $642.9k | Reduced -39.9k |
| Squarepoint Ops LLC 0.00% of their portfolio | 67.9k $631.1k | Added +54.2k |
| Encompass More Asset Management 0.15% of their portfolio | 66.7k $619.9k | New |
| Nan Fung Group Holdings Ltd 0.93% of their portfolio | 63.7k $592.0k | Reduced -350.5k |
| XTX Topco Ltd 0.02% of their portfolio | 62.8k $583.4k | New |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 58.2k $541.1k | New |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 53.8k $499.8k | Added +1.0k |
| Legal & General Group Plc 0.00% of their portfolio | 53.2k $494.2k | Reduced -4.2k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 51.5k $478.3k | Reduced -90.5k |
| LMR Partners LLP 0.01% of their portfolio | 50.0k $464.5k | New |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 43.4k $403.4k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 41.8k $388.7k | Unchanged |
| ALPS ADVISORS INC 0.00% of their portfolio | 41.6k $386.5k | Reduced -14.7k |
| NEOS Investment Management LLC 0.00% of their portfolio | 40.9k $380.0k | Added +3.4k |
| Tema ETFs LLC 0.10% of their portfolio | 40.9k $380.0k | Added +3.4k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 40.6k $377.2k | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 40.0k $371.2k | Reduced -106.6k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 39.9k $371.2k | Reduced -4.4k |
| CITIGROUP INC 0.00% of their portfolio | 39.4k $366.4k | Reduced -76.0k |
| SIMPLEX TRADING, LLC 0.01% of their portfolio | 38.5k $358.0k | Added +32.9k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 38.3k $355.6k | Reduced -4.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 36.3k $337.3k | Reduced -184.3k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 35.9k $333.2k | Reduced -4.8k |