Vault-13

REPARE THERAPEUTICS INC RPTX

COM · Common Stock · CUSIP 760273102

0 institutional holders -46 vs Q4 2025
—reported value*
0 new 0 added 0 reduced 45 sold out net sold ≈ $65.1m (-25.0m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable.

Trends to Q1 2026

Institutional holders

Managers reporting a position, each quarter

050100Q3 22: 72Q4 22: 82Q1 23: 78Q2 23: 79Q3 23: 77Q4 23: 70Q1 24: 72Q2 24: 62Q3 24: 57Q4 24: 55Q1 25: 51Q2 25: 51Q3 25: 45Q4 25: 46Q1 26: 00Q3 22Q3 23Q3 24Q3 25Q1 26
Numbers
QuarterHolders
Q3 202272
Q4 202282
Q1 202378
Q2 202379
Q3 202377
Q4 202370
Q1 202472
Q2 202462
Q3 202457
Q4 202455
Q1 202551
Q2 202551
Q3 202545
Q4 202546
Q1 20260

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
50050Q2 24: 26 bought or addedQ2 24: 33 cut or sold outQ3 24: 18 bought or addedQ3 24: 26 cut or sold outQ3 24Q4 24: 19 bought or addedQ4 24: 30 cut or sold outQ1 25: 19 bought or addedQ1 25: 29 cut or sold outQ1 25Q2 25: 15 bought or addedQ2 25: 22 cut or sold outQ3 25: 12 bought or addedQ3 25: 16 cut or sold outQ3 25Q4 25: 21 bought or addedQ4 25: 20 cut or sold outQ1 26: 0 bought or addedQ1 26: 45 cut or sold outQ1 26
Numbers
QuarterBought or addedCut or sold out
Q2 20242633
Q3 20241826
Q4 20241930
Q1 20251929
Q2 20251522
Q3 20251216
Q4 20252120
Q1 2026045

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$250k$500k$750k$1mQ2 25 calls: $162.2kQ2 25 puts: $0Q2 25P/C 0.00Q3 25 calls: $407.8kQ3 25 puts: $0Q3 25P/C 0.00Q4 25 calls: $872.0kQ4 25 puts: $564.5kQ4 25P/C 0.65Q1 26 calls: $0Q1 26 puts: $0Q1 26P/C —
Numbers
QuarterCallsPutsP/C
Q2 2025$162.2k$00.00
Q3 2025$407.8k$00.00
Q4 2025$872.0k$564.5k0.65
Q1 2026$0$0—

Biggest buyers

None

Biggest sellers

BVF INC/IL Sold out -10,333,600-10.3m
Blue Owl Capital Holdings LP Sold out -3,443,659-3.4m
ORBIMED ADVISORS LLC Sold out -3,322,488-3.3m
Redmile Group, LLC Sold out -1,586,174-1.6m
Rangeley Capital, LLC Sold out -1,287,829-1.3m
MARSHALL WACE, LLP Sold out -1,115,744-1.1m
RENAISSANCE TECHNOLOGIES LLC Sold out -981,360-981.4k
ACADIAN ASSET MANAGEMENT LLC Sold out -618,672-618.7k
TWO SIGMA INVESTMENTS, LP Sold out -333,694-333.7k
JANE STREET GROUP, LLC Sold out -278,304-278.3k

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Shay Capital LLC 13G · passive investor new · filed 2026-01-27 6.7% new 2.9m 2026-01-27

Fell to 5% or below in the last year: Blue Owl Capital Holdings LP (0.0%, 2026-05-14), BIOTECHNOLOGY VALUE FUND L P (0.0%, 2026-01-30), Versant Venture Capital V, L.P. (0.2%, 2025-11-21)

Holders, Q1 2026

#ManagerLocationShares Value% of their portfolioChangeShares change