REPLIGEN CORP RGEN
COM · Common Stock · CUSIP 759916109 · ISIN US7599161095
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersWaltham, MA
- Founded1981
- Websiterepligen.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($12.9m this quarter). Holder counts are more reliable. Shares outstanding: 55.8m as of 2023-10-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $179.74. Options: 14 managers hold calls ($143.2m notional), 15 hold puts ($83.2m).
Trends to Q4 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 434 |
| Q4 2022 | 443 |
| Q1 2023 | 448 |
| Q2 2023 | 448 |
| Q3 2023 | 440 |
| Q4 2023 | 467 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 222 | 201 |
| Q1 2023 | 207 | 201 |
| Q2 2023 | 218 | 219 |
| Q3 2023 | 213 | 217 |
| Q4 2023 | 209 | 203 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2023 | $48.5m | $34.2m | 0.70 |
| Q2 2023 | $33.5m | $27.4m | 0.82 |
| Q3 2023 | $36.9m | $34.0m | 0.92 |
| Q4 2023 | $143.2m | $83.2m | 0.58 |
Biggest buyers
| Point72 Asset Management, L.P. | New | +596.9k |
| MORGAN STANLEY | Added | +596.7k |
| VOYA INVESTMENT MANAGEMENT LLC | Added | +484.5k |
| MACQUARIE GROUP LTD | Added | +306.7k |
| Holocene Advisors, LP | New | +304.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +208.4k |
| Nuveen Asset Management, LLC | Added | +167.0k |
| AMERICAN CENTURY COMPANIES INC | Added | +150.1k |
| JPMORGAN CHASE & CO | Added | +140.0k |
| Invesco Ltd. | Added | +126.5k |
Biggest sellers
| Perpetual Ltd | Sold out | -558.9k |
| FMR LLC | Reduced | -341.2k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -295.1k |
| FRANKLIN RESOURCES INC | Reduced | -249.7k |
| AMERIPRISE FINANCIAL INC | Reduced | -168.4k |
| CITADEL ADVISORS LLC | Reduced | -117.1k |
| Atika Capital Management LLC | Sold out | -92.7k |
| SANDS CAPITAL MANAGEMENT, LLC | Reduced | -75.0k |
| Squarepoint Ops LLC | Reduced | -70.0k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -67.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $46.6m259.0k shares |
| Twin Tree Management, LP | Added | $28.4m157.8k shares |
| Caption Management, LLC | New | $16.2m90.0k shares |
| SIMPLEX TRADING, LLC | Added | $12.0m67.0k shares |
| CITADEL ADVISORS LLC | Added | $10.2m56.6k shares |
| JANE STREET GROUP, LLC | Reduced | $8.2m45.4k shares |
| BANK OF AMERICA CORP /DE/ | Reduced | $5.4m30.0k shares |
| Walleye Trading LLC | Added | $5.1m28.5k shares |
| CITIGROUP INC | New | $4.1m23.0k shares |
| GROUP ONE TRADING LLC | Added | $2.4m13.3k shares |
Biggest puts
| Twin Tree Management, LP | Added | $37.1m206.4k shares |
| Walleye Trading LLC | Added | $10.4m58.0k shares |
| Parallax Volatility Advisers, L.P. | New | $9.0m50.0k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $5.4m30.3k shares |
| Jefferies Financial Group Inc. | New | $4.6m25.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $4.0m22.4k shares |
| CITADEL ADVISORS LLC | Added | $4.0m22.2k shares |
| D. E. Shaw & Co., Inc. | Unchanged | $2.7m15.0k shares |
| SIMPLEX TRADING, LLC | Added | $2.2m12.1k shares |
| BANK OF MONTREAL /CAN/ | New | $1.5m8.1k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +7.9 pts · filed 2026-10-07 | 13.0% |
| BlackRock, Inc. 13G · institution filed 2025-04-24 | 9.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (3.1%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Roy T. Eddleman Living Trust (4.8%, 2026-02-13)
Insider purchases and sales in Q4 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2022 | 1 | $109.4k | 1 | $396.1k | — |
| Q2 2022 | 0 | — | 1 | $2.2m | — |
| Q3 2022 | 0 | — | 6 | $15.7m | — |
| Q4 2022 | 0 | — | 1 | $5.0m | — |
| Q1 2023 | 0 | — | 1 | $1.1m | — |
| Q2 2023 | 1 | $238.3k | 0 | — | — |
| Q3 2023 | 0 | — | 1 | $145.7k | — |
| Q4 2023 | 0 | — | 1 | $557.3k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-11-10 | Gebski Christine Officer | Sold | $557.3k3.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2023
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.04% of their portfolio | 7.9m $1.4bn | Reduced -26.5k |
| VANGUARD GROUP INC 0.02% of their portfolio | 5.1m $913.1m | Added +33.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.10% of their portfolio | 4.0m $721.0m | Added +208.4k |
| FMR LLC 0.03% of their portfolio | 1.9m $338.5m | Reduced -341.2k |
| STATE STREET CORP 0.01% of their portfolio | 1.7m $306.3m | Added +49.4k |
| MACQUARIE GROUP LTD 0.33% of their portfolio | 1.6m $282.1m | Added +306.7k |
| BROWN CAPITAL MANAGEMENT LLC 4.11% of their portfolio | 1.5m $274.2m | Added +83.4k |
| Artisan Partners Limited Partnership 0.43% of their portfolio | 1.5m $273.8m | Reduced -34.1k |
| SANDS CAPITAL MANAGEMENT, LLC 0.82% of their portfolio | 1.5m $268.9m | Reduced -75.0k |
| Bank of New York Mellon Corp 0.04% of their portfolio | 1.2m $206.9m | Reduced -45.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.04% of their portfolio | 1.1m $198.0m | Reduced -295.1k |
| MORGAN STANLEY 0.01% of their portfolio | 1.1m $194.6m | Added +596.7k |
| AMERIPRISE FINANCIAL INC 0.05% of their portfolio | 984.8k $177.1m | Reduced -168.4k |
| Champlain Investment Partners, LLC 0.99% of their portfolio | 926.4k $166.6m | Added +71.2k |
| Impax Asset Management Group plc 0.66% of their portfolio | 912.8k $163.2m | Reduced -59.8k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.47% of their portfolio | 905.8k $162.9m | Reduced -41.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 883.0k $158.5m | Added +30.8k |
| Invesco Ltd. 0.04% of their portfolio | 833.1k $149.8m | Added +126.5k |
| ALLIANCEBERNSTEIN L.P. 0.05% of their portfolio | 777.0k $139.7m | Reduced -8.1k |
| Harding Loevner LP 0.72% of their portfolio | 716.3k $129.0m | Reduced -9.1k |
| Conestoga Capital Advisors, LLC 1.91% of their portfolio | 709.7k $127.6m | Added +2.6k |
| Point72 Asset Management, L.P. 0.32% of their portfolio | 596.9k $107.3m | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.11% of their portfolio | 584.2k $105.0m | Added +484.5k |
| PARNASSUS INVESTMENTS, LLC 0.22% of their portfolio | 550.1k $98.9m | Unchanged |
| Nuveen Asset Management, LLC 0.03% of their portfolio | 541.1k $97.3m | Added +167.0k |
| Stephens Investment Management Group LLC 1.28% of their portfolio | 486.8k $87.5m | Reduced -15.3k |
| DF DENT & CO INC 1.16% of their portfolio | 486.4k $87.4m | Added +104.9k |
| Baird Financial Group, Inc. 0.19% of their portfolio | 470.7k $84.6m | Added +105.7k |
| RIVERBRIDGE PARTNERS LLC 1.01% of their portfolio | 450.9k $81.1m | Reduced -8.8k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 447.4k $80.4m | Reduced -24.5k |
| BAMCO INC /NY/ 0.21% of their portfolio | 445.8k $80.1m | Reduced -13.0k |
| FRED ALGER MANAGEMENT, LLC 0.42% of their portfolio | 428.5k $77.0m | Reduced -56.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.11% of their portfolio | 425.4k $76.5m | Reduced -17.7k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 415.9k $74.8m | Added +1.2k |
| T. Rowe Price Investment Management, Inc. 0.05% of their portfolio | 403.4k $72.5m | Added +120.1k |
| FEDERATED HERMES, INC. 0.18% of their portfolio | 396.6k $71.3m | Reduced -49.3k |
| 12 West Capital Management LP 6.25% of their portfolio | 368.2k $66.2m | Reduced -46.0k |
| AMERICAN CENTURY COMPANIES INC 0.05% of their portfolio | 368.0k $66.2m | Added +150.1k |
| Amundi 0.03% of their portfolio | 367.2k $63.6m | Added +367 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 342.5k $61.6m | Added +15.8k |
| BESSEMER GROUP INC 0.12% of their portfolio | 332.2k $59.7m | Added +20.3k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.17% of their portfolio | 330.8k $59.5m | Reduced -14.5k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 322.0k $57.9m | Added +140.0k |
| MARSHALL WACE, LLP 0.11% of their portfolio | 320.8k $57.7m | Reduced -13.5k |
| Holocene Advisors, LP 0.21% of their portfolio | 304.9k $54.8m | New |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 302.0k $54.3m | Added +16.4k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.31% of their portfolio | 294.2k $52.9m | Added +49.7k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 284.1k $51.1m | Reduced -249.7k |
| CITADEL ADVISORS LLC 0.05% of their portfolio | 280.5k $50.4m | Reduced -117.1k |
| EAGLE ASSET MANAGEMENT INC 0.27% of their portfolio | 280.1k $50.4m | Reduced -59.9k |
| Allspring Global Investments Holdings, LLC 0.08% of their portfolio | 275.9k $49.6m | Added +14.7k |
| NORGES BANK 0.01% of their portfolio | 268.1k $48.2m | Added +1.2k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 263.5k $47.4m | Reduced -36.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio | 263.1k $47.3m | Added +15.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.03% of their portfolio | 262.7k $47.2m | Added +70.0k |
| LORD, ABBETT & CO. LLC 0.08% of their portfolio | 262.2k $47.1m | Added +26.9k |
| SEI INVESTMENTS CO 0.07% of their portfolio | 258.9k $46.6m | Added +7.1k |
| AMERICAN CAPITAL MANAGEMENT INC 1.43% of their portfolio | 232.6k $41.8m | Added +4.3k |
| PALISADE CAPITAL MANAGEMENT, LP 1.09% of their portfolio | 228.7k $41.1m | Reduced -20.7k |
| TimesSquare Capital Management, LLC 0.54% of their portfolio | 205.9k $37.0m | Added +78.6k |
| Thrivent Financial for Lutherans 0.07% of their portfolio | 181.6k $32.7m | Reduced -10.0k |
| Ranger Investment Management, L.P. 1.89% of their portfolio | 173.8k $31.3m | Added +733 |
| Swiss National Bank 0.02% of their portfolio | 165.6k $29.8m | Reduced -4.5k |
| Legal & General Group Plc 0.01% of their portfolio | 163.2k $29.4m | Reduced -32.7k |
| RHUMBLINE ADVISERS 0.03% of their portfolio | 157.1k $28.2m | Reduced -3.1k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 155.5k $28.0m | Added +47.6k |
| ZEVENBERGEN CAPITAL INVESTMENTS LLC 0.54% of their portfolio | 130.5k $23.5m | Added +1.4k |
| WCM INVESTMENT MANAGEMENT, LLC 0.07% of their portfolio | 130.0k $24.1m | Added +5.2k |
| Granahan Investment Management, LLC 0.77% of their portfolio | 129.7k $23.3m | Reduced -3.1k |
| COMERICA BANK 0.11% of their portfolio | 127.1k $22.9m | Added +11.2k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 126.6k $22.8m | Reduced -67.6k |
| Artemis Investment Management LLP 0.33% of their portfolio | 125.4k $22.6m | New |
| GREAT LAKES ADVISORS, LLC 0.21% of their portfolio | 122.5k $22.0m | Reduced -1.1k |
| GENEVA CAPITAL MANAGEMENT LLC 0.41% of their portfolio | 120.2k $21.6m | Added +2.2k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.35% of their portfolio | 119.0k $21.4m | Unchanged |
| BARCLAYS PLC 0.01% of their portfolio | 114.2k $20.5m | Added +36.8k |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.09% of their portfolio | 112.9k $20.3m | Reduced -657 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 112.0k $20.1m | Added +1.6k |
| Sumitomo Mitsui Trust Group, Inc. 0.01% of their portfolio | 108.9k $19.6m | Reduced -2.6k |
| Curi Capital, LLC 0.59% of their portfolio | 107.0k $19.2m | Added +547 |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 103.9k $18.7m | Reduced -2.5k |
| BRAIDWELL LP 0.68% of their portfolio | 102.7k $18.5m | Reduced -15.7k |
| AWM Investment Company, Inc. 2.37% of their portfolio | 100.0k $18.0m | Unchanged |
| WAFRA INC. 1.02% of their portfolio | 96.9k $17.4m | Added +41.8k |
| CREDIT SUISSE AG/ 0.02% of their portfolio | 95.3k $17.1m | Added +4.4k |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 91.8k $16.5m | Added +22.3k |
| NORTH STAR ASSET MANAGEMENT INC 0.84% of their portfolio | 91.7k $16.5m | Reduced -41 |
| Iron Triangle Partners LP 1.92% of their portfolio | 82.5k $14.8m | New |
| D. E. Shaw & Co., Inc. 0.02% of their portfolio | 82.5k $14.8m | Added +67.9k |
| NZS Capital, LLC 0.78% of their portfolio | 82.5k $14.8m | Added +45.3k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 82.4k $14.8m | Reduced -699 |
| California Public Employees Retirement System 0.01% of their portfolio | 79.4k $14.3m | Reduced -4.1k |
| CONGRESS ASSET MANAGEMENT CO 0.11% of their portfolio | 76.8k $13.8m | Added +52.9k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.05% of their portfolio | 70.4k $12.7m | Reduced -2.9k |
| Pembroke Management, LTD 1.46% of their portfolio | 65.4k $11.8m | Added +24.0k |
| Retirement Systems of Alabama 0.05% of their portfolio | 65.0k $11.7m | Added +288 |
| Alberta Investment Management Corp 0.11% of their portfolio | 64.3k $11.6m | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 62.6k $11.3m | Reduced -1.2k |
| TD Asset Management Inc 0.01% of their portfolio | 61.6k $11.1m | Added +2.4k |
| W1M Asset Management Ltd 0.93% of their portfolio | 61.6k $11.1m | Added +6.2k |