REPLIGEN CORP RGEN
COM · Common Stock · CUSIP 759916109 · ISIN US7599161095
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersWaltham, MA
- Founded1981
- Websiterepligen.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($17.7m this quarter). Holder counts are more reliable. Shares outstanding: 55.8m as of 2023-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $141.57. Options: 15 managers hold calls ($33.5m notional), 12 hold puts ($27.4m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 434 |
| Q4 2022 | 443 |
| Q1 2023 | 448 |
| Q2 2023 | 448 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 222 | 201 |
| Q1 2023 | 207 | 201 |
| Q2 2023 | 218 | 219 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $45.4m | $69.1m | 1.52 |
| Q4 2022 | $83.9m | $50.6m | 0.60 |
| Q1 2023 | $48.5m | $34.2m | 0.70 |
| Q2 2023 | $33.5m | $27.4m | 0.82 |
Biggest buyers
| BlackRock Inc. | Added | +522.1k |
| DF DENT & CO INC | Added | +297.1k |
| MARSHALL WACE, LLP | Added | +263.3k |
| T. Rowe Price Investment Management, Inc. | Added | +223.2k |
| RIVERBRIDGE PARTNERS LLC | New | +214.8k |
| AMERIPRISE FINANCIAL INC | Added | +208.0k |
| Artisan Partners Limited Partnership | Added | +177.5k |
| Impax Asset Management Group plc | Added | +145.7k |
| BAMCO INC /NY/ | Added | +138.0k |
| NATIXIS | New | +116.1k |
Biggest sellers
| FMR LLC | Reduced | -1.6m |
| Invesco Ltd. | Reduced | -713.9k |
| Echo Street Capital Management LLC | Reduced | -579.5k |
| LORD, ABBETT & CO. LLC | Reduced | -401.9k |
| FRANKLIN RESOURCES INC | Reduced | -310.2k |
| ENVESTNET ASSET MANAGEMENT INC | Reduced | -305.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Sold out | -267.4k |
| Allspring Global Investments Holdings, LLC | Sold out | -189.7k |
| GILDER GAGNON HOWE & CO LLC | Reduced | -187.4k |
| Alyeska Investment Group, L.P. | Reduced | -153.5k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $11.1m78.4k shares |
| Jefferies Financial Group Inc. | New | $4.1m29.2k shares |
| JANE STREET GROUP, LLC | Added | $3.9m27.9k shares |
| GROUP ONE TRADING LLC | Added | $3.5m24.5k shares |
| CITADEL ADVISORS LLC | Reduced | $2.8m19.9k shares |
| UBS Group AG | Added | $2.1m15.0k shares |
| D. E. Shaw & Co., Inc. | Reduced | $1.4m10.0k shares |
| Walleye Capital LLC | New | $1.1m7.8k shares |
| Walleye Trading LLC | Added | $1.1m7.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $806.0k5.7k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $10.5m74.1k shares |
| CITADEL ADVISORS LLC | Added | $5.9m41.8k shares |
| Twin Tree Management, LP | Reduced | $2.6m18.7k shares |
| Walleye Trading LLC | Added | $2.5m17.5k shares |
| D. E. Shaw & Co., Inc. | Added | $2.1m15.0k shares |
| JANE STREET GROUP, LLC | Reduced | $1.7m12.3k shares |
| SIMPLEX TRADING, LLC | Added | $1.1m7.7k shares |
| Walleye Capital LLC | New | $495.1k3.5k shares |
| WOLVERINE TRADING, LLC | New | $249.2k1.8k shares |
| Jefferies Financial Group Inc. | New | $113.2k800 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +7.9 pts · filed 2026-10-07 | 13.0% |
| BlackRock, Inc. 13G · institution filed 2025-04-24 | 9.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (3.1%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Roy T. Eddleman Living Trust (4.8%, 2026-02-13)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 4 | $7.6m | — |
| Q1 2022 | 1 | $109.4k | 1 | $396.1k | — |
| Q2 2022 | 0 | — | 1 | $2.2m | — |
| Q3 2022 | 0 | — | 6 | $15.7m | — |
| Q4 2022 | 0 | — | 1 | $5.0m | — |
| Q1 2023 | 0 | — | 1 | $1.1m | — |
| Q2 2023 | 1 | $238.3k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-05-08 | Madaus Martin D Director | Bought | $78.1k500 shares |
| 2023-05-05 | Madaus Martin D Director | Bought | $79.6k500 shares |
| 2023-05-04 | Madaus Martin D Director | Bought | $80.6k500 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.03% of their portfolio | 7.8m $1.1bn | Added +522.1k |
| VANGUARD GROUP INC 0.02% of their portfolio | 5.1m $715.3m | Reduced -25.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.07% of their portfolio | 3.7m $525.8m | Reduced -45.0k |
| FMR LLC 0.03% of their portfolio | 2.5m $348.9m | Reduced -1.6m |
| STATE STREET CORP 0.01% of their portfolio | 1.7m $233.6m | Added +14.6k |
| SANDS CAPITAL MANAGEMENT, LLC 0.70% of their portfolio | 1.6m $225.5m | Reduced -20.7k |
| BROWN CAPITAL MANAGEMENT LLC 2.90% of their portfolio | 1.4m $204.4m | Added +4.8k |
| Artisan Partners Limited Partnership 0.32% of their portfolio | 1.4m $197.9m | Added +177.5k |
| WELLINGTON MANAGEMENT GROUP LLP 0.04% of their portfolio | 1.4m $193.4m | Reduced -126.2k |
| AMERIPRISE FINANCIAL INC 0.06% of their portfolio | 1.3m $180.1m | Added +208.0k |
| MACQUARIE GROUP LTD 0.20% of their portfolio | 1.2m $174.2m | Added +98.7k |
| Bank of New York Mellon Corp 0.03% of their portfolio | 1.1m $149.7m | Reduced -12.2k |
| Impax Asset Management Group plc 0.57% of their portfolio | 1.0m $142.4m | Added +145.7k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.43% of their portfolio | 945.9k $133.8m | Added +34.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 834.3k $117.8m | Added +48.7k |
| ALLIANCEBERNSTEIN L.P. 0.04% of their portfolio | 767.6k $108.6m | Reduced -105.0k |
| FRANKLIN RESOURCES INC 0.05% of their portfolio | 707.4k $100.1m | Reduced -310.2k |
| Conestoga Capital Advisors, LLC 1.53% of their portfolio | 682.6k $96.6m | Reduced -2.9k |
| Invesco Ltd. 0.03% of their portfolio | 676.1k $95.6m | Reduced -713.9k |
| Champlain Investment Partners, LLC 0.53% of their portfolio | 610.7k $86.4m | Added +54.7k |
| Perpetual Ltd 0.70% of their portfolio | 576.5k $81.6m | Added +100.1k |
| FRED ALGER MANAGEMENT, LLC 0.41% of their portfolio | 570.1k $80.7m | Reduced -21.4k |
| Stephens Investment Management Group LLC 1.11% of their portfolio | 501.1k $70.9m | Reduced -27.4k |
| 12 West Capital Management LP 5.83% of their portfolio | 480.5k $68.0m | Reduced -90.6k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 460.7k $65.2m | Added +5.0k |
| MORGAN STANLEY 0.01% of their portfolio | 457.7k $64.7m | Added +91.5k |
| FEDERATED HERMES, INC. 0.16% of their portfolio | 450.5k $63.7m | Reduced -184 |
| MARSHALL WACE, LLP 0.14% of their portfolio | 449.5k $63.6m | Added +263.3k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.08% of their portfolio | 436.8k $61.8m | Added +4.3k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 391.1k $55.3m | Reduced -47.1k |
| DF DENT & CO INC 0.74% of their portfolio | 385.1k $54.5m | Added +297.1k |
| BAMCO INC /NY/ 0.14% of their portfolio | 359.0k $50.8m | Added +138.0k |
| Baird Financial Group, Inc. 0.13% of their portfolio | 351.4k $49.7m | Reduced -9.3k |
| EAGLE ASSET MANAGEMENT INC 0.27% of their portfolio | 339.9k $48.1m | Reduced -132.1k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.15% of their portfolio | 335.6k $47.5m | Added +113.9k |
| Amundi 0.02% of their portfolio | 322.9k $45.9m | Added +111.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 318.0k $45.0m | Added +5.7k |
| BESSEMER GROUP INC 0.09% of their portfolio | 295.8k $41.9m | Added +10.7k |
| T. Rowe Price Investment Management, Inc. 0.03% of their portfolio | 279.8k $39.6m | Added +223.2k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.24% of their portfolio | 271.0k $38.3m | Added +28.4k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 260.3k $36.8m | Added +19.6k |
| PALISADE CAPITAL MANAGEMENT, LP 0.92% of their portfolio | 245.3k $34.7m | Added +10.0k |
| Alyeska Investment Group, L.P. 0.26% of their portfolio | 244.5k $34.6m | Reduced -153.5k |
| NORGES BANK 0.01% of their portfolio | 242.2k $34.3m | Reduced -119.1k |
| LORD, ABBETT & CO. LLC 0.06% of their portfolio | 234.2k $33.1m | Reduced -401.9k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 231.2k $32.7m | Reduced -16.4k |
| TimesSquare Capital Management, LLC 0.47% of their portfolio | 229.9k $32.5m | Added +57.2k |
| AMERICAN CAPITAL MANAGEMENT INC 1.12% of their portfolio | 228.4k $32.3m | Added +55.9k |
| RIVERBRIDGE PARTNERS LLC 0.38% of their portfolio | 214.8k $30.4m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 214.8k $30.4m | Added +6.2k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 214.1k $30.3m | Added +9.8k |
| Legal & General Group Plc 0.01% of their portfolio | 198.9k $28.1m | Reduced -4.1k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 195.8k $27.7m | Reduced -9.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio | 192.2k $32.4m | Unchanged |
| Swiss National Bank 0.02% of their portfolio | 190.9k $27.0m | Reduced -18.0k |
| SEI INVESTMENTS CO 0.05% of their portfolio | 187.1k $26.5m | Added +48.1k |
| Thrivent Financial for Lutherans 0.06% of their portfolio | 185.9k $26.3m | Added +2.8k |
| Ranger Investment Management, L.P. 1.53% of their portfolio | 179.4k $25.4m | Reduced -28.7k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 175.3k $27.9m | Reduced -55.2k |
| RHUMBLINE ADVISERS 0.03% of their portfolio | 162.2k $22.9m | Added +3.7k |
| Granahan Investment Management, LLC 0.66% of their portfolio | 150.8k $21.3m | Added +39.6k |
| WCM INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio | 126.9k $18.0m | Added +1.5k |
| GENEVA CAPITAL MANAGEMENT LLC 0.34% of their portfolio | 123.6k $17.5m | Reduced -6.5k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.28% of their portfolio | 119.0k $16.8m | Unchanged |
| NATIXIS 0.14% of their portfolio | 116.1k $16.4m | New |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.08% of their portfolio | 113.6k $16.1m | Unchanged |
| Sumitomo Mitsui Trust Group, Inc. 0.01% of their portfolio | 111.2k $15.7m | Reduced -21.5k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 111.2k $15.7m | Added +42.5k |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 110.3k $15.6m | Added +869 |
| ZEVENBERGEN CAPITAL INVESTMENTS LLC 0.37% of their portfolio | 110.1k $15.6m | Added +2.9k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 109.8k $15.5m | Added +27.1k |
| BNP PARIBAS FINANCIAL MARKETS 0.03% of their portfolio | 104.5k $14.8m | Reduced -6.6k |
| Curi Capital, LLC 0.48% of their portfolio | 102.6k $14.5m | Added +1.8k |
| AWM Investment Company, Inc. 1.92% of their portfolio | 100.0k $14.1m | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.01% of their portfolio | 99.7k $14.1m | Added +79.4k |
| Atika Capital Management LLC 1.65% of their portfolio | 92.7k $13.1m | Reduced -17 |
| BRAIDWELL LP 0.43% of their portfolio | 92.0k $13.0m | New |
| CREDIT SUISSE AG/ 0.01% of their portfolio | 91.8k $13.0m | Added +49.6k |
| NORTH STAR ASSET MANAGEMENT INC 0.71% of their portfolio | 91.3k $12.9m | Added +2.3k |
| UBS Group AG 0.01% of their portfolio | 90.2k $12.8m | Added +34.3k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 85.7k $12.1m | Reduced -2.8k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 85.4k $12.1m | Added +80.0k |
| BARCLAYS PLC 0.01% of their portfolio | 84.4k $11.9m | Added +5.8k |
| California Public Employees Retirement System 0.01% of their portfolio | 82.7k $11.7m | Reduced -6.8k |
| Cercano Management LLC 0.40% of their portfolio | 82.2k $11.6m | Added +19.2k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.07% of their portfolio | 78.4k $11.1m | Reduced -1.5k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 76.1k $10.8m | Reduced -305.0k |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 67.5k $9.5m | Added +65.7k |
| Retirement Systems of Alabama 0.04% of their portfolio | 66.7k $9.4m | Reduced -738 |
| Eversept Partners, LP 0.99% of their portfolio | 66.1k $9.3m | Added +60.4k |
| RAYMOND JAMES & ASSOCIATES 0.01% of their portfolio | 64.9k $9.2m | Reduced -10.7k |
| Alberta Investment Management Corp 0.09% of their portfolio | 64.3k $9.1m | Unchanged |
| Pier Capital, LLC 1.29% of their portfolio | 63.7k $9.0m | Added +16.4k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.02% of their portfolio | 63.0k $8.9m | Reduced -1.0k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 60.7k $8.6m | Reduced -695 |
| TWO SIGMA INVESTMENTS, LP 0.02% of their portfolio | 57.3k $8.1m | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 56.3k $8.0m | Added +282 |
| VAN ECK ASSOCIATES CORP 0.02% of their portfolio | 56.2k $7.9m | Reduced -4.6k |
| Jump Financial, LLC 0.28% of their portfolio | 54.2k $7.7m | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 52.5k $7.4m | Added +33.3k |