RELAY THERAPEUTICS INC RLAY
COM · Common Stock · CUSIP 75943R102
Company in Cambridge, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersCambridge, MA
- Founded2016
- Websiterelaytx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($25.0k this quarter). Holder counts are more reliable. Shares outstanding: 133.9m as of 2024-08-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.52. Options: 3 managers hold calls ($12.1k notional), 4 hold puts ($117.4k).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 162 |
| Q4 2022 | 165 |
| Q1 2023 | 158 |
| Q2 2023 | 162 |
| Q3 2023 | 173 |
| Q4 2023 | 178 |
| Q1 2024 | 190 |
| Q2 2024 | 180 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 95 | 64 |
| Q1 2023 | 75 | 79 |
| Q2 2023 | 91 | 62 |
| Q3 2023 | 90 | 59 |
| Q4 2023 | 81 | 82 |
| Q1 2024 | 101 | 69 |
| Q2 2024 | 95 | 78 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $194.9k | $105.6k | 0.54 |
| Q4 2023 | $71.9k | $99.9k | 1.39 |
| Q1 2024 | $60.9k | $98.1k | 1.61 |
| Q2 2024 | $12.1k | $117.4k | 9.71 |
Biggest buyers
| Logos Global Management LP | New | +2.6m |
| Casdin Capital, LLC | Added | +1.0m |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Added | +984.4k |
| CITADEL ADVISORS LLC | Added | +926.1k |
| MILLENNIUM MANAGEMENT LLC | Added | +921.3k |
| BlackRock Inc. | Added | +746.5k |
| JPMORGAN CHASE & CO | Added | +492.3k |
| Bellevue Group AG | Added | +450.5k |
| MPM BIOIMPACT LLC | Added | +442.4k |
| MARSHALL WACE, LLP | New | +276.7k |
Biggest sellers
| ArrowMark Colorado Holdings LLC | Reduced | -3.5m |
| MORGAN STANLEY | Reduced | -2.2m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -1.8m |
| STATE STREET CORP | Reduced | -1.8m |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Sold out | -1.7m |
| FMR LLC | Reduced | -1.0m |
| Point72 Asset Management, L.P. | Sold out | -952.0k |
| Balyasny Asset Management L.P. | Reduced | -933.6k |
| BRAIDWELL LP | Reduced | -737.2k |
| CITIGROUP INC | Reduced | -371.4k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $11.1k1.7k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.0k300 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $113.4k17.4k shares |
| CITADEL ADVISORS LLC | Reduced | $3.9k600 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Reduced | $0100 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +0.6 pts · filed 2026-08-07 | 10.0% |
| Casdin Capital, LLC 13G · passive investor no change · filed 2026-02-17 | 7.5% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor +1.1 pts · filed 2026-08-10 | 6.4% |
| BlackRock, Inc. 13G · institution -2.7 pts · filed 2025-04-17 | 6.1% |
| Commodore Capital LP 13G · passive investor -4.4 pts · filed 2026-08-14 | 5.5% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 6 | $4.4m | — |
| Q4 2022 | 0 | — | 5 | $2.2m | — |
| Q1 2023 | 0 | — | 5 | $2.9m | — |
| Q2 2023 | 0 | — | 4 | $108.7k | — |
| Q3 2023 | 0 | — | 4 | $96.7k | — |
| Q4 2023 | 0 | — | 4 | $66.5k | — |
| Q1 2024 | 0 | — | 4 | $95.3k | — |
| Q2 2024 | 0 | — | 4 | $653.4k | $599.1k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-27 | Catinazzo Thomas Chief Financial Officer | Sold plan | $58.5k9.4k shares |
| 2024-06-27 | Bergstrom Donald A President, R&D | Sold | $4.1k648 shares |
| 2024-06-27 | Adams Brian Chief Legal Officer | Sold | $1.8k295 shares |
| 2024-06-27 | Rahmer Peter Officer | Sold | $1.5k245 shares |
| 2024-06-05 | Rahmer Peter Officer | Sold plan | $144.4k20.4k shares |
| 2024-06-04 | Rahmer Peter Officer | Sold plan | $269.6k40.6k shares |
| 2024-06-03 | Rahmer Peter Officer | Sold plan | $128.5k19.9k shares |
| 2024-04-29 | Bergstrom Donald A President, R&D | Sold | $17.1k2.7k shares |
| 2024-04-29 | Catinazzo Thomas Chief Financial Officer | Sold | $10.8k1.7k shares |
| 2024-04-29 | Adams Brian Chief Legal Officer | Sold | $10.4k1.6k shares |
| 2024-04-29 | Rahmer Peter Officer | Sold | $8.6k1.3k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| SB INVESTMENT ADVISERS (UK) LTD 1.68% of their portfolio | 27.9m $181.9m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 11.7m $76.3m | Reduced -110.8k |
| BlackRock Inc. 0.00% of their portfolio | 10.5m $68.7m | Added +746.5k |
| Casdin Capital, LLC 4.21% of their portfolio | 8.4m $55.1m | Added +1.0m |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 7.9m $51.7m | Added +492.3k |
| Bellevue Group AG 0.68% of their portfolio | 6.4m $41.6m | Added +450.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 5.0m $32.9m | Reduced -1.8m |
| STATE STREET CORP 0.00% of their portfolio | 4.2m $27.7m | Reduced -1.8m |
| Nextech Invest Ltd. 4.22% of their portfolio | 3.8m $25.1m | Unchanged |
| NORGES BANK 0.00% of their portfolio | 3.3m $21.6m | Reduced -73.3k |
| BRAIDWELL LP 0.61% of their portfolio | 3.0m $19.6m | Reduced -737.2k |
| Logos Global Management LP 0.98% of their portfolio | 2.6m $17.0m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.4m $15.4m | Added +148.0k |
| Boxer Capital, LLC 0.62% of their portfolio | 1.8m $11.9m | Unchanged |
| Finepoint Capital LP 2.97% of their portfolio | 1.6m $10.5m | Added +115.2k |
| Alphabet Inc. 0.52% of their portfolio | 1.6m $10.2m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.5m $9.9m | Reduced -80.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.5m $9.7m | Reduced -278.6k |
| MPM BIOIMPACT LLC 1.29% of their portfolio | 1.3m $8.3m | Added +442.4k |
| MORGAN STANLEY 0.00% of their portfolio | 1.2m $8.1m | Reduced -2.2m |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.03% of their portfolio | 1.2m $7.8m | Added +984.4k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 1.2m $7.6m | Added +926.1k |
| BAKER BROS. ADVISORS LP 0.10% of their portfolio | 1.2m $7.6m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.1m $7.5m | Added +921.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 909.0k $5.9m | Added +145.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 821.4k $5.4m | Reduced -90.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 814.4k $5.3m | Reduced -14.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 795.5k $5.2m | Added +53.8k |
| Integral Health Asset Management, LLC 0.49% of their portfolio | 750.0k $4.9m | Added +25.0k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 730.0k $4.8m | Added +142.3k |
| Candriam S.C.A. 0.03% of their portfolio | 703.4k $4.6m | Added +195.0k |
| Driehaus Capital Management LLC 0.04% of their portfolio | 616.2k $4.0m | Added +218.3k |
| BESSEMER GROUP INC 0.01% of their portfolio | 584.5k $3.8m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 562.9k $3.7m | Added +24.3k |
| ArrowMark Colorado Holdings LLC 0.04% of their portfolio | 541.1k $3.5m | Reduced -3.5m |
| ALGERT GLOBAL LLC 0.10% of their portfolio | 476.9k $3.1m | Added +175.0k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 450.3k $2.9m | Added +87.9k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 446.8k $2.9m | Added +184.9k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 424.8k $2.8m | Added +30.5k |
| Prosight Management, LP 0.75% of their portfolio | 385.0k $2.5m | Reduced -65.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 354.7k $2.3m | Added +48.2k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 312.4k $2.0m | Reduced -24.0k |
| HighTower Advisors, LLC 0.00% of their portfolio | 303.3k $2.0m | Added +56.1k |
| HarbourVest Partners LLC 1.03% of their portfolio | 296.4k $1.9m | Unchanged |
| BAILLIE GIFFORD & CO 0.00% of their portfolio | 284.1k $1.9m | Reduced -69.2k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 276.7k $1.8m | New |
| Woodline Partners LP 0.02% of their portfolio | 273.6k $1.8m | Added +608 |
| Rhenman & Partners Asset Management AB 0.14% of their portfolio | 230.0k $1.5m | Unchanged |
| PDT Partners, LLC 0.14% of their portfolio | 226.6k $1.5m | Added +73.6k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 219.7k $1.4m | Reduced -230.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 215.6k $1.4m | Reduced -19.6k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 209.6k $1.4m | Reduced -347.6k |
| Susquehanna Portfolio Strategies, LLC 0.06% of their portfolio | 208.4k $1.4m | Unchanged |
| TD Asset Management Inc 0.00% of their portfolio | 206.1k $1.3m | Reduced -152.6k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 198.4k $1.3m | Added +57.0k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 193.9k $1.3m | Reduced -270.1k |
| UBS Group AG 0.00% of their portfolio | 189.3k $1.2m | Reduced -98.6k |
| Fernwood Investment Management, LLC 0.38% of their portfolio | 185.8k $1.2m | Unchanged |
| Trexquant Investment LP 0.02% of their portfolio | 184.6k $1.2m | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 178.1k $1.2m | Added +28.9k |
| Swiss National Bank 0.00% of their portfolio | 167.8k $1.1m | Added +4.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 163.9k $1.1m | Added +7.5k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 156.3k $1.0m | Added +18.8k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 153.8k $1.0m | Unchanged |
| CONGRESS ASSET MANAGEMENT CO 0.01% of their portfolio | 147.6k $962.4k | Reduced -1.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 145.0k $945.3k | New |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 120.0k $782.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 115.3k $751.6k | Reduced -24.7k |
| Invesco Ltd. 0.00% of their portfolio | 114.5k $746.6k | Reduced -2.4k |
| CAXTON ASSOCIATES LP 0.03% of their portfolio | 107.6k $701.3k | Reduced -23.2k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 106.2k $692.2k | Added +92.2k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 105.5k $688.0k | New |
| Man Group plc 0.00% of their portfolio | 101.4k $660.9k | Reduced -86.6k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 99.8k $650.7k | Added +41.4k |
| GSA CAPITAL PARTNERS LLP 0.04% of their portfolio | 98.4k $642.0k | Added +71.0k |
| ICONIQ Capital, LLC 0.01% of their portfolio | 94.7k $617.4k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 87.8k $572.5k | Added +719 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 84.4k $550.5k | Added +418 |
| MARTINGALE ASSET MANAGEMENT L P 0.01% of their portfolio | 77.0k $501.9k | Added +19.1k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 76.5k $499.0k | Added +7.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 71.9k $468.9k | Added +18.5k |
| FMR LLC 0.00% of their portfolio | 70.5k $459.5k | Reduced -1.0m |
| Intellectus Partners, LLC 0.12% of their portfolio | 67.7k $441.2k | Reduced -1.6k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 67.2k $438.4k | Added +52.7k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 66.2k $431.3k | Added +709 |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 66.0k $430.2k | Reduced -933.6k |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 64.3k $419.0k | Added +9.4k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 61.4k $400.0k | New |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 60.0k $490.0k | Reduced -8.9k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 57.7k $376.1k | Added +11.6k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 56.1k $364.2k | First filing |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 55.5k $361.5k | Added +10.8k |
| NEOS Investment Management LLC 0.01% of their portfolio | 54.6k $356.0k | Added +31.8k |
| TrueMark Investments, LLC 0.12% of their portfolio | 54.4k $355.0k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 54.4k $354.6k | Reduced -9.3k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 53.5k $348.9k | First filing |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 53.4k $348.4k | Added +38.1k |
| ROYCE & ASSOCIATES LP 0.00% of their portfolio | 48.4k $315.4k | Added +34.2k |
| Engineers Gate Manager LP 0.01% of their portfolio | 48.3k $314.9k | Reduced -1.1k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.01% of their portfolio | 46.7k $304.5k | New |