RELAY THERAPEUTICS INC RLAY
COM · Common Stock · CUSIP 75943R102
Company in Cambridge, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersCambridge, MA
- Founded2016
- Websiterelaytx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.7m this quarter). Holder counts are more reliable. Shares outstanding: 122.1m as of 2023-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $12.59. Options: 7 managers hold calls ($1.4m notional), 6 hold puts ($1.0m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 162 |
| Q4 2022 | 165 |
| Q1 2023 | 158 |
| Q2 2023 | 162 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 95 | 64 |
| Q1 2023 | 75 | 79 |
| Q2 2023 | 91 | 62 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $7.2m | $1.8m | 0.25 |
| Q4 2022 | $1.7m | $3.0k | 0.00 |
| Q1 2023 | $5.1m | $4.4m | 0.85 |
| Q2 2023 | $1.4m | $1.0m | 0.72 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | New | +1.6m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.5m |
| STATE STREET CORP | Added | +1.3m |
| BAKER BROS. ADVISORS LP | Added | +876.1k |
| ArrowMark Colorado Holdings LLC | Added | +748.5k |
| JPMORGAN CHASE & CO | Added | +694.1k |
| BlackRock Inc. | Added | +432.0k |
| ALLIANCEBERNSTEIN L.P. | Added | +385.1k |
| Nextech Invest Ltd. | Added | +323.2k |
| Balyasny Asset Management L.P. | New | +318.0k |
Biggest sellers
| FMR LLC | Reduced | -14.7m |
| Driehaus Capital Management LLC | Reduced | -989.2k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -762.8k |
| GREAT POINT PARTNERS LLC | Sold out | -658.1k |
| HARVARD MANAGEMENT CO INC | Sold out | -541.1k |
| Artal Group S.A. | Reduced | -460.0k |
| Boxer Capital, LLC | Reduced | -350.0k |
| Artisan Partners Limited Partnership | Sold out | -294.7k |
| Candriam S.C.A. | Reduced | -267.8k |
| BANK OF AMERICA CORP /DE/ | Reduced | -247.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $841.5k67.0k shares |
| Walleye Capital LLC | New | $187.1k14.9k shares |
| JANE STREET GROUP, LLC | New | $158.3k12.6k shares |
| CITADEL ADVISORS LLC | Reduced | $111.8k8.9k shares |
| SIMPLEX TRADING, LLC | New | $75.0k6.0k shares |
| GROUP ONE TRADING LLC | Added | $49.0k3.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $666.9k53.1k shares |
| CITADEL ADVISORS LLC | Reduced | $268.8k21.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $57.0k4.6k shares |
| GROUP ONE TRADING LLC | Added | $23.9k1.9k shares |
| Walleye Capital LLC | New | $1.3k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +0.6 pts · filed 2026-08-07 | 10.0% |
| Casdin Capital, LLC 13G · passive investor no change · filed 2026-02-17 | 7.5% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor +1.1 pts · filed 2026-08-10 | 6.4% |
| BlackRock, Inc. 13G · institution -2.7 pts · filed 2025-04-17 | 6.1% |
| Commodore Capital LP 13G · passive investor -4.4 pts · filed 2026-08-14 | 5.5% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 4 | $2.1m | — |
| Q1 2022 | 0 | — | 4 | $1.7m | — |
| Q2 2022 | 0 | — | 5 | $3.8m | — |
| Q3 2022 | 0 | — | 6 | $4.4m | — |
| Q4 2022 | 0 | — | 5 | $2.2m | — |
| Q1 2023 | 0 | — | 5 | $2.9m | — |
| Q2 2023 | 0 | — | 4 | $108.7k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-06-27 | Bergstrom Donald A President, R&D | Sold | $7.8k647 shares |
| 2023-06-27 | Catinazzo Thomas Chief Financial Officer | Sold | $3.6k294 shares |
| 2023-06-27 | Adams Brian Chief Legal Officer | Sold | $3.6k294 shares |
| 2023-06-27 | Rahmer Peter Officer | Sold | $3.0k244 shares |
| 2023-04-28 | Bergstrom Donald A President, R&D | Sold | $31.8k2.9k shares |
| 2023-04-28 | Catinazzo Thomas Chief Financial Officer | Sold | $22.5k2.0k shares |
| 2023-04-28 | Adams Brian Chief Legal Officer | Sold | $21.6k1.9k shares |
| 2023-04-28 | Rahmer Peter Officer | Sold | $18.5k1.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| SB INVESTMENT ADVISERS (UK) LTD 2.67% of their portfolio | 27.9m $350.5m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 10.5m $132.2m | Added +29.1k |
| BlackRock Inc. 0.00% of their portfolio | 8.4m $105.1m | Added +432.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 8.3m $104.8m | Added +1.5m |
| STATE STREET CORP 0.00% of their portfolio | 7.2m $90.6m | Added +1.3m |
| Casdin Capital, LLC 6.58% of their portfolio | 6.0m $75.3m | Added +300.0k |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 5.0m $62.7m | Added +694.1k |
| Bellevue Group AG 0.75% of their portfolio | 4.2m $52.4m | Reduced -1.8k |
| EcoR1 Capital, LLC 1.38% of their portfolio | 4.2m $52.3m | Unchanged |
| ArrowMark Colorado Holdings LLC 0.47% of their portfolio | 3.4m $42.9m | Added +748.5k |
| BVF INC/IL 1.09% of their portfolio | 3.1m $39.2m | Unchanged |
| FMR LLC 0.00% of their portfolio | 3.0m $37.1m | Reduced -14.7m |
| T. Rowe Price Investment Management, Inc. 0.02% of their portfolio | 2.3m $28.4m | Added +41.8k |
| PERCEPTIVE ADVISORS LLC 0.71% of their portfolio | 1.9m $24.4m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.9m $23.6m | Added +126.7k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 1.9m $23.5m | Added +385.1k |
| Boxer Capital, LLC 1.06% of their portfolio | 1.8m $22.8m | Reduced -350.0k |
| NORGES BANK 0.00% of their portfolio | 1.6m $20.3m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 1.6m $19.8m | New |
| Alphabet Inc. 1.06% of their portfolio | 1.6m $19.7m | Unchanged |
| MPM BIOIMPACT LLC 3.43% of their portfolio | 1.4m $17.0m | Added +128.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.3m $16.2m | Reduced -109.6k |
| Artal Group S.A. 0.49% of their portfolio | 1.2m $15.2m | Reduced -460.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.2m $14.6m | Reduced -71.4k |
| BAKER BROS. ADVISORS LP 0.08% of their portfolio | 1.2m $14.6m | Added +876.1k |
| Candriam S.C.A. 0.09% of their portfolio | 971.1k $12.2m | Reduced -267.8k |
| Nextech Invest Ltd. 4.05% of their portfolio | 948.7k $11.9m | Added +323.2k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 886.5k $14.6m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 794.2k $10.0m | Reduced -78.2k |
| MORGAN STANLEY 0.00% of their portfolio | 777.5k $9.8m | Added +215.3k |
| Finepoint Capital LP 3.05% of their portfolio | 701.6k $8.8m | Reduced -144.7k |
| Integral Health Asset Management, LLC 1.15% of their portfolio | 700.0k $8.8m | Reduced -70.0k |
| Rock Springs Capital Management LP 0.20% of their portfolio | 674.0k $8.5m | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 672.4k $8.4m | Added +18.5k |
| Rafferty Asset Management, LLC 0.04% of their portfolio | 627.0k $7.9m | Added +183.4k |
| Driehaus Capital Management LLC 0.09% of their portfolio | 593.0k $7.4m | Reduced -989.2k |
| BESSEMER GROUP INC 0.02% of their portfolio | 584.5k $7.3m | Unchanged |
| Jefferies Financial Group Inc. 0.12% of their portfolio | 434.2k $5.5m | Added +306.9k |
| BAILLIE GIFFORD & CO 0.00% of their portfolio | 411.3k $5.2m | Reduced -4.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 378.8k $4.8m | Reduced -247.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 363.9k $4.6m | Added +123.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 321.8k $4.0m | Reduced -54.2k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 318.0k $4.0m | New |
| BARCLAYS PLC 0.00% of their portfolio | 309.2k $3.9m | Added +114.7k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 308.0k $3.9m | Added +287.3k |
| HarbourVest Partners LLC 1.06% of their portfolio | 296.4k $3.7m | Unchanged |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 276.5k $3.5m | New |
| TD Asset Management Inc 0.00% of their portfolio | 263.5k $3.3m | Added +46.7k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 260.1k $3.3m | Added +9.1k |
| Woodline Partners LP 0.04% of their portfolio | 250.0k $3.1m | Reduced -25.0k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 220.5k $2.8m | Reduced -47.6k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 205.6k $2.6m | Added +37.4k |
| CITIGROUP INC 0.00% of their portfolio | 201.7k $2.5m | Reduced -154.4k |
| UBS Group AG 0.00% of their portfolio | 194.7k $2.4m | Added +24.0k |
| Rhenman & Partners Asset Management AB 0.25% of their portfolio | 190.0k $2.4m | Unchanged |
| GILDER GAGNON HOWE & CO LLC 0.03% of their portfolio | 186.1k $2.3m | Added +83.5k |
| Fernwood Investment Management, LLC 0.82% of their portfolio | 185.1k $2.3m | Unchanged |
| Cubist Systematic Strategies, LLC 0.02% of their portfolio | 177.5k $2.2m | New |
| Swiss National Bank 0.00% of their portfolio | 171.8k $2.2m | Added +2.1k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 148.4k $1.9m | Added +12.8k |
| CONGRESS ASSET MANAGEMENT CO 0.02% of their portfolio | 146.2k $1.8m | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 141.2k $1.8m | Added +51.5k |
| Invesco Ltd. 0.00% of their portfolio | 126.9k $1.6m | Added +52.9k |
| ALGERT GLOBAL LLC 0.07% of their portfolio | 124.2k $1.6m | Added +90.0k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 118.6k $1.5m | Added +37.1k |
| Jump Financial, LLC 0.05% of their portfolio | 116.5k $1.5m | New |
| PROFUND ADVISORS LLC 0.08% of their portfolio | 113.1k $1.4m | Added +30.8k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 99.4k $1.2m | Reduced -1.3k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% of their portfolio | 96.4k $1.2m | Added +52.3k |
| ICONIQ Capital, LLC 0.02% of their portfolio | 94.7k $1.2m | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 88.3k $1.1m | Reduced -16.1k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 87.7k $1.1m | Reduced -762.8k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 76.7k $963.7k | Reduced -25.5k |
| Legal & General Group Plc 0.00% of their portfolio | 76.6k $962.7k | Added +1.6k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.00% of their portfolio | 72.8k $914.4k | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 68.8k $864.5k | Reduced -3.7k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 61.5k $772.6k | Added +15.9k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 61.2k $773.7k | Added +4.4k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 60.0k $768.0k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 59.4k $746.3k | Reduced -195.5k |
| GSA CAPITAL PARTNERS LLP 0.07% of their portfolio | 59.4k $746.0k | New |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 58.7k $737.7k | New |
| Intellectus Partners, LLC 0.18% of their portfolio | 48.6k $609.9k | Added +21.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 46.1k $578.4k | Added +1.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 45.7k $573.5k | Reduced -111.7k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 43.5k $545.8k | Added +2.4k |
| HARBOR CAPITAL ADVISORS, INC. 0.10% of their portfolio | 40.3k $505.9k | New |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 38.9k $488.6k | Unchanged |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 37.4k $469.0k | Reduced -46 |
| HRT FINANCIAL LP 0.00% of their portfolio | 36.5k $458.0k | New |
| Blackstone Inc. 0.00% of their portfolio | 35.6k $447.4k | Unchanged |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 35.6k $447.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 35.2k $442.0k | Reduced -20.7k |
| Verition Fund Management LLC 0.01% of their portfolio | 34.4k $432.5k | New |
| E Fund Management Co., Ltd. 0.03% of their portfolio | 33.7k $423.0k | Added +8.5k |
| Corton Capital Inc. 0.19% of their portfolio | 32.7k $410.4k | Added +19.9k |
| HighVista Strategies LLC 0.19% of their portfolio | 32.2k $404.4k | Reduced -97.0k |
| NOMURA ASSET MANAGEMENT CO LTD 0.00% of their portfolio | 31.9k $400.4k | Added +9.3k |
| BRANDYWINE MANAGERS, LLC 0.26% of their portfolio | 31.8k $399.5k | Unchanged |
| M&T Bank Corp 0.00% of their portfolio | 31.4k $393.5k | Added +4.0k |