REGENXBIO INC RGNX
COM · Common Stock · CUSIP 75901B107 · ISIN US75901B1070
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersRockville, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($92.8k this quarter). Holder counts are more reliable. Shares outstanding: 50.5m as of 2025-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $8.21. Options: 7 managers hold calls ($1.2m notional), 7 hold puts ($971.6k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 183 |
| Q4 2022 | 182 |
| Q1 2023 | 175 |
| Q2 2023 | 168 |
| Q3 2023 | 161 |
| Q4 2023 | 172 |
| Q1 2024 | 189 |
| Q2 2024 | 182 |
| Q3 2024 | 187 |
| Q4 2024 | 178 |
| Q1 2025 | 165 |
| Q2 2025 | 160 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 79 | 77 |
| Q4 2023 | 74 | 82 |
| Q1 2024 | 99 | 75 |
| Q2 2024 | 96 | 78 |
| Q3 2024 | 93 | 73 |
| Q4 2024 | 87 | 94 |
| Q1 2025 | 83 | 94 |
| Q2 2025 | 83 | 79 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $1.5m | $6.7m | 4.43 |
| Q4 2024 | $1.4m | $494.2k | 0.35 |
| Q1 2025 | $565.6k | $817.9k | 1.45 |
| Q2 2025 | $1.2m | $971.6k | 0.83 |
Biggest buyers
| BlackRock, Inc. | Added | +1.3m |
| GOLDMAN SACHS GROUP INC | Added | +1.0m |
| STATE STREET CORP | Added | +777.6k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +438.4k |
| AQR CAPITAL MANAGEMENT LLC | Added | +309.6k |
| Nuveen, LLC | Added | +295.5k |
| 22NW, LP | Added | +255.0k |
| Squarepoint Ops LLC | Added | +209.1k |
| Voss Capital, LP | Added | +185.0k |
| Y-Intercept (Hong Kong) Ltd | New | +177.0k |
Biggest sellers
| MORGAN STANLEY | Reduced | -1.1m |
| CITADEL ADVISORS LLC | Reduced | -735.7k |
| Balyasny Asset Management L.P. | Reduced | -601.4k |
| JPMORGAN CHASE & CO | Reduced | -512.3k |
| Cubist Systematic Strategies, LLC | Sold out | -357.8k |
| Aquilo Capital Management, LLC | Sold out | -271.3k |
| Avidity Partners Management LP | Sold out | -260.0k |
| Integral Health Asset Management, LLC | Reduced | -225.0k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -220.9k |
| HRT FINANCIAL LP | Sold out | -183.4k |
Biggest calls
| Caption Management, LLC | Unchanged | $246.3k30.0k shares |
| JANE STREET GROUP, LLC | New | $239.7k29.2k shares |
| SIMPLEX TRADING, LLC | Added | $223.0k27.2k shares |
| BARCLAYS PLC | Unchanged | $175.7k21.4k shares |
| CITADEL ADVISORS LLC | Added | $169.9k20.7k shares |
| GROUP ONE TRADING LLC | Added | $118.2k14.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| Caption Management, LLC | Unchanged | $246.3k30.0k shares |
| CITADEL ADVISORS LLC | Reduced | $213.5k26.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $188.0k22.9k shares |
| BARCLAYS PLC | Unchanged | $175.7k21.4k shares |
| SIMPLEX TRADING, LLC | Added | $103.0k12.6k shares |
| GROUP ONE TRADING LLC | Reduced | $45.2k5.5k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Redmile Group, LLC 13G · passive investor filed 2025-08-14 | 9.9% |
| BlackRock, Inc. 13G · institution -3.7 pts · filed 2025-04-24 | 7.3% |
| JPMORGAN CHASE & CO 13G · institution +0.9 pts · filed 2026-10-13 | 5.3% |
| STATE STREET CORP 13G · institution +0.9 pts · filed 2026-05-12 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), BlackRock Portfolio Management LLC (4.1%, 2026-01-21; now reported by BlackRock, Inc.)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 1 | $886.0k | $886.0k |
| Q1 2024 | 0 | — | 2 | $1.9m | $1.9m |
| Q2 2024 | 0 | — | 1 | $510.0k | $510.0k |
| Q3 2024 | 0 | — | 3 | $1.1m | $1.1m |
| Q4 2024 | 0 | — | 1 | $101.1k | $101.1k |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 1 | $163.0k | $163.0k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-05-12 | Mills Kenneth T. Director | Sold plan | $163.0k20.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 6.8m $55.5m | Added +1.3m |
| Redmile Group, LLC 4.17% of their portfolio | 4.8m $39.2m | Reduced -19.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 3.9m $31.6m | Reduced -512.3k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.4m $28.1m | Reduced -51.8k |
| STATE STREET CORP 0.00% of their portfolio | 1.8m $15.1m | Added +777.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.8m $14.7m | Added +1.0m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $9.3m | Added +21.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.1m $9.2m | Reduced -25.0k |
| MORGAN STANLEY 0.00% of their portfolio | 994.8k $8.2m | Reduced -1.1m |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 930.2k $7.6m | Added +309.6k |
| 22NW, LP 4.78% of their portfolio | 923.7k $7.6m | Added +255.0k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 797.1k $6.5m | Reduced -601.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 735.2k $6.0m | Added +438.4k |
| Integral Health Asset Management, LLC 0.54% of their portfolio | 700.0k $5.7m | Reduced -225.0k |
| Voss Capital, LP 0.33% of their portfolio | 575.0k $4.7m | Added +185.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 572.5k $4.7m | Reduced -79.4k |
| Assenagon Asset Management S.A. 0.01% of their portfolio | 572.5k $4.7m | Reduced -712 |
| Trexquant Investment LP 0.05% of their portfolio | 560.4k $4.6m | Added +101.8k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 457.1k $3.8m | Added +64.3k |
| Nuveen, LLC 0.00% of their portfolio | 420.2k $3.5m | Added +295.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 400.1k $3.3m | Reduced -7.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 387.5k $3.2m | Added +21.0k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 372.8k $3.1m | Added +42.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 311.1k $2.6m | Reduced -17.9k |
| UBS Group AG 0.00% of their portfolio | 307.9k $2.5m | Added +108.3k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 291.9k $2.4m | Reduced -735.7k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 242.4k $2.0m | Reduced -171.7k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 240.3k $2.0m | Added +83.0k |
| BARCLAYS PLC 0.00% of their portfolio | 239.5k $2.0m | Added +119.9k |
| GSA CAPITAL PARTNERS LLP 0.13% of their portfolio | 226.6k $1.9m | Added +95.3k |
| Exome Asset Management LLC 1.58% of their portfolio | 226.1k $1.9m | Reduced -179.2k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 222.3k $1.8m | Reduced -3.2k |
| ArchPoint Investors 0.53% of their portfolio | 220.5k $1.8m | Reduced -1.0k |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 220.0k $1.8m | Reduced -75.0k |
| Squarepoint Ops LLC 0.00% of their portfolio | 219.3k $1.8m | Added +209.1k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 208.0k $1.7m | Reduced -118.8k |
| ADAR1 Capital Management, LLC 0.28% of their portfolio | 207.8k $1.7m | Reduced -142.5k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 206.4k $1.7m | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 187.3k $1.5m | Reduced -7.9k |
| Y-Intercept (Hong Kong) Ltd 0.04% of their portfolio | 177.0k $1.5m | New |
| FMR LLC 0.00% of their portfolio | 171.5k $1.4m | Added +3.1k |
| Hennion & Walsh Asset Management, Inc. 0.05% of their portfolio | 154.5k $1.3m | Reduced -4.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 152.7k $1.3m | Added +12.2k |
| Nebula Research & Development LLC 0.11% of their portfolio | 151.3k $1.2m | New |
| MOORE CAPITAL MANAGEMENT, LP 0.02% of their portfolio | 150.0k $1.2m | Added +50.0k |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 149.0k $1.2m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 144.1k $1.2m | Added +2.7k |
| IEQ CAPITAL, LLC 0.01% of their portfolio | 129.6k $1.1m | Added +78.6k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 125.4k $1.0m | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 124.9k $1.0m | Reduced -72.1k |
| Invesco Ltd. 0.00% of their portfolio | 113.2k $929.4k | Added +33.7k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 111.9k $919.1k | Reduced -220.9k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 111.5k $915.4k | Added +12.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 110.1k $903.6k | Added +8.5k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 103.8k $852.2k | Reduced -8.2k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 90.8k $744.6k | Added +35.0k |
| Man Group plc 0.00% of their portfolio | 84.8k $696.2k | Added +52.6k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.07% of their portfolio | 82.3k $675.9k | Reduced -30.2k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 74.6k $622.0k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 72.2k $592.3k | Added +995 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 64.7k $531.4k | Added +11.8k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 60.7k $498.0k | New |
| Graham Capital Management, L.P. 0.02% of their portfolio | 60.1k $493.7k | Added +8.1k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 59.5k $488.6k | Reduced -34.3k |
| Lion Point Capital, LP 3.22% of their portfolio | 57.8k $474.1k | Unchanged |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 57.6k $473.0k | Reduced -10.2k |
| BRADLEY FOSTER & SARGENT INC/CT 0.01% of their portfolio | 54.9k $450.6k | New |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 53.5k $439.6k | New |
| Engineers Gate Manager LP 0.01% of their portfolio | 51.8k $425.4k | Added +1.1k |
| Militia Capital Partners, LP 0.09% of their portfolio | 47.2k $387.5k | New |
| CWM, LLC 0.00% of their portfolio | 46.8k $384.0k | Added +20.1k |
| Cerity Partners LLC 0.00% of their portfolio | 46.5k $382.1k | Added +14.7k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 45.4k $372.0k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 41.4k $339.7k | Reduced -4.0k |
| LPL Financial LLC 0.00% of their portfolio | 38.0k $312.3k | Added +16.5k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 30.6k $267.7k | Added +13.5k |
| CITIGROUP INC 0.00% of their portfolio | 30.4k $250.0k | Reduced -6.7k |
| Jump Financial, LLC 0.00% of their portfolio | 30.4k $249.8k | Reduced -76.9k |
| AlphaQuest LLC 0.02% of their portfolio | 30.1k $246.9k | Reduced -30.2k |
| Virtu Financial LLC 0.01% of their portfolio | 29.5k $243.0k | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 29.1k $238.9k | New |
| SHERBROOKE PARK ADVISERS LLC 0.10% of their portfolio | 28.6k $235.1k | Added +4.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 28.0k $230.0k | Added +1.8k |
| Pale Fire Capital SE 0.02% of their portfolio | 27.8k $228.6k | Added +2.0k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 27.1k $222.5k | Added +5.7k |
| ALPS ADVISORS INC 0.00% of their portfolio | 27.0k $222.0k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 26.2k $215.4k | Added +2.7k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 23.6k $193.8k | Reduced -4.1k |
| Polymer Capital Management (US) LLC 0.03% of their portfolio | 23.4k $192.2k | New |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 20.5k $168.3k | New |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 20.2k $166.2k | Reduced -29.3k |
| Quantinno Capital Management LP 0.00% of their portfolio | 20.0k $164.3k | Reduced -685 |
| DNB Asset Management AS 0.00% of their portfolio | 18.4k $151.0k | Reduced -95 |
| Pallas Capital Advisors LLC 0.01% of their portfolio | 17.4k $142.9k | Added +7.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.0k $139.7k | Reduced -375 |
| Caliber Wealth Management, LLC / KS 0.01% of their portfolio | 16.1k $132.1k | Reduced -1.5k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 15.7k $128.6k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 14.9k $122.5k | Reduced -48.2k |
| Creative Planning 0.00% of their portfolio | 14.6k $120.0k | Reduced -1.5k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 14.5k $118.7k | Added +1.1k |