REGENXBIO INC RGNX
COM · Common Stock · CUSIP 75901B107 · ISIN US75901B1070
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersRockville, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($88.9k this quarter). Holder counts are more reliable. Shares outstanding: 49.5m as of 2024-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $7.73. Options: 8 managers hold calls ($1.4m notional), 5 hold puts ($494.2k).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 183 |
| Q4 2022 | 182 |
| Q1 2023 | 175 |
| Q2 2023 | 168 |
| Q3 2023 | 161 |
| Q4 2023 | 172 |
| Q1 2024 | 189 |
| Q2 2024 | 182 |
| Q3 2024 | 187 |
| Q4 2024 | 178 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 78 | 90 |
| Q2 2023 | 79 | 83 |
| Q3 2023 | 79 | 77 |
| Q4 2023 | 74 | 82 |
| Q1 2024 | 99 | 75 |
| Q2 2024 | 96 | 78 |
| Q3 2024 | 93 | 73 |
| Q4 2024 | 87 | 94 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $2.4m | $1.4m | 0.57 |
| Q2 2024 | $850.4k | $1.0m | 1.22 |
| Q3 2024 | $1.5m | $6.7m | 4.43 |
| Q4 2024 | $1.4m | $494.2k | 0.35 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | Added | +1.1m |
| MORGAN STANLEY | Added | +653.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +500.0k |
| CITADEL ADVISORS LLC | Added | +382.2k |
| Cubist Systematic Strategies, LLC | New | +361.3k |
| Voss Capital, LP | New | +332.8k |
| Assenagon Asset Management S.A. | Added | +296.7k |
| RENAISSANCE TECHNOLOGIES LLC | New | +271.3k |
| TWO SIGMA INVESTMENTS, LP | Added | +263.5k |
| Qube Research & Technologies Ltd | Added | +159.9k |
Biggest sellers
| BlackRock, Inc. | Reduced | -3.4m |
| VANGUARD GROUP INC | Reduced | -1.4m |
| JPMORGAN CHASE & CO | Reduced | -818.1k |
| Avidity Partners Management LP | Reduced | -600.6k |
| STATE STREET CORP | Reduced | -597.0k |
| Aquilo Capital Management, LLC | Reduced | -584.4k |
| ADAR1 Capital Management, LLC | Reduced | -398.9k |
| Integral Health Asset Management, LLC | Reduced | -375.0k |
| WS MANAGEMENT LLLP | Sold out | -300.0k |
| PRINCIPAL FINANCIAL GROUP INC | Sold out | -214.4k |
Biggest calls
| GROUP ONE TRADING LLC | Added | $538.0k69.6k shares |
| CITADEL ADVISORS LLC | Added | $348.6k45.1k shares |
| CITIGROUP INC | Reduced | $192.5k24.9k shares |
| ADAR1 Capital Management, LLC | Unchanged | $137.6k17.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $111.3k14.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $40.0k5.2k shares |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | Not comparable | $30.0k80.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $245.0k31.7k shares |
| CITIGROUP INC | Reduced | $192.5k24.9k shares |
| GROUP ONE TRADING LLC | Added | $38.6k5.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $18.0k2.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Redmile Group, LLC 13G · passive investor filed 2025-08-14 | 9.9% |
| BlackRock, Inc. 13G · institution -3.7 pts · filed 2025-04-24 | 7.3% |
| JPMORGAN CHASE & CO 13G · institution +0.9 pts · filed 2026-10-13 | 5.3% |
| STATE STREET CORP 13G · institution +0.9 pts · filed 2026-05-12 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), BlackRock Portfolio Management LLC (4.1%, 2026-01-21; now reported by BlackRock, Inc.)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 1 | $69.6k | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 1 | $886.0k | $886.0k |
| Q1 2024 | 0 | — | 2 | $1.9m | $1.9m |
| Q2 2024 | 0 | — | 1 | $510.0k | $510.0k |
| Q3 2024 | 0 | — | 3 | $1.1m | $1.1m |
| Q4 2024 | 0 | — | 1 | $101.1k | $101.1k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-10-01 | KARABELAS ARGERIS N Director | Sold plan | $101.1k10.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 5.5m $42.3m | Reduced -3.4m |
| Redmile Group, LLC 2.58% of their portfolio | 4.8m $37.1m | Reduced -98.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 4.1m $32.0m | Reduced -818.1k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.0m $23.1m | Reduced -1.4m |
| STATE STREET CORP 0.00% of their portfolio | 2.2m $16.9m | Reduced -597.0k |
| MORGAN STANLEY 0.00% of their portfolio | 2.0m $15.5m | Added +653.4k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.3m $10.2m | Added +1.1m |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 1.2m $9.2m | Added +67.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.2m $9.1m | Added +21.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $8.5m | Added +5.6k |
| Integral Health Asset Management, LLC 0.62% of their portfolio | 900.0k $7.0m | Reduced -375.0k |
| Assenagon Asset Management S.A. 0.01% of their portfolio | 856.6k $6.6m | Added +296.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 756.2k $5.8m | Added +12.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 585.4k $4.5m | Added +382.2k |
| Avidity Partners Management LP 0.41% of their portfolio | 532.0k $4.1m | Reduced -600.6k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 500.0k $3.9m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 465.3k $3.6m | Reduced -22.7k |
| NORGES BANK 0.00% of their portfolio | 449.4k $3.5m | Not comparable |
| Sonic GP LLC 6.87% of their portfolio | 403.1k $3.1m | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 389.4k $3.0m | Added +263.5k |
| HRT FINANCIAL LP 0.02% of their portfolio | 363.4k $2.8m | Added +129.4k |
| Cubist Systematic Strategies, LLC 0.05% of their portfolio | 361.3k $2.8m | New |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 354.0k $2.7m | Added +159.9k |
| RTW INVESTMENTS, LP 0.04% of their portfolio | 350.0k $2.7m | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 349.7k $2.7m | Reduced -68.0k |
| Aquilo Capital Management, LLC 4.58% of their portfolio | 346.3k $2.7m | Reduced -584.4k |
| Voss Capital, LP 0.19% of their portfolio | 332.8k $2.6m | New |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 308.1k $2.4m | Added +93.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 284.5k $2.2m | Added +12.9k |
| Siren, L.L.C. 0.10% of their portfolio | 284.0k $2.2m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 281.2k $2.2m | Reduced -165.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 271.3k $2.1m | New |
| ArchPoint Investors 0.56% of their portfolio | 221.5k $1.7m | Reduced -2.8k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 208.0k $1.6m | Reduced -1.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 200.4k $1.5m | Added +15.7k |
| UBS Group AG 0.00% of their portfolio | 193.3k $1.5m | Added +81.8k |
| Jump Financial, LLC 0.03% of their portfolio | 192.7k $1.5m | Added +114.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 188.8k $1.5m | Added +39.6k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 180.0k $1.4m | Added +112.0k |
| ADAR1 Capital Management, LLC 0.27% of their portfolio | 170.1k $1.3m | Reduced -398.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 164.9k $1.3m | Added +126.1k |
| Hennion & Walsh Asset Management, Inc. 0.06% of their portfolio | 164.7k $1.3m | Added +13.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 161.1k $1.2m | Reduced -159.3k |
| Trexquant Investment LP 0.01% of their portfolio | 150.0k $1.2m | New |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 149.0k $1.2m | Unchanged |
| Y-Intercept (Hong Kong) Ltd 0.07% of their portfolio | 137.4k $1.1m | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 134.5k $1.0m | Added +108.8k |
| BARCLAYS PLC 0.00% of their portfolio | 127.1k $982.2k | Added +11.0k |
| CITIGROUP INC 0.00% of their portfolio | 114.8k $887.5k | Added +19.3k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 112.3k $868.2k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 108.8k $841.1k | Added +53.4k |
| XTX Topco Ltd 0.07% of their portfolio | 108.1k $835.8k | Added +94.9k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 105.7k $817.0k | Reduced -83.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 100.5k $774.6k | Added +2.8k |
| MOORE CAPITAL MANAGEMENT, LP 0.01% of their portfolio | 100.0k $773.0k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 96.1k $742.8k | Added +75.7k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 95.0k $734.6k | Added +7.7k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 93.8k $725.2k | Added +17.2k |
| Walleye Capital LLC 0.01% of their portfolio | 88.1k $681.4k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 84.8k $629.3k | Added +48.3k |
| Swiss National Bank 0.00% of their portfolio | 81.5k $630.0k | Unchanged |
| Opaleye Management Inc. 0.11% of their portfolio | 80.0k $618.4k | New |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 74.6k $546.0k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 74.3k $574.1k | Reduced -40.8k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 73.5k $568.2k | First filing |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 72.2k $558.0k | Added +6.1k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 63.4k $489.9k | Added +8.3k |
| PDT Partners, LLC 0.04% of their portfolio | 63.0k $487.1k | New |
| Point72 Asia (Singapore) Pte. Ltd. 0.12% of their portfolio | 57.8k $447.1k | New |
| Lion Point Capital, LP 2.34% of their portfolio | 57.8k $446.4k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 53.9k $416.6k | Reduced -5.1k |
| Invesco Ltd. 0.00% of their portfolio | 52.1k $402.9k | Reduced -84.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 48.4k $374.4k | Added +12.3k |
| Engineers Gate Manager LP 0.01% of their portfolio | 45.7k $353.2k | New |
| Alpine Global Management, LLC 0.05% of their portfolio | 45.4k $350.7k | New |
| Legal & General Group Plc 0.00% of their portfolio | 44.8k $346.5k | Reduced -72.9k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 43.5k $336.3k | Added +3.0k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 41.2k $318.2k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 39.6k $305.8k | Reduced -330 |
| Sigma Planning Corp 0.01% of their portfolio | 37.3k $288.4k | Reduced -900 |
| Squarepoint Ops LLC 0.00% of their portfolio | 37.2k $287.8k | Reduced -2.5k |
| Quantessence Capital LLC 0.11% of their portfolio | 34.9k $269.7k | First filing |
| NAPATREE CAPITAL LLC 0.15% of their portfolio | 33.5k $259.1k | Reduced -1.6k |
| Allianz Asset Management GmbH 0.00% of their portfolio | 31.8k $245.8k | Reduced -7.5k |
| BIT Capital GmbH 0.02% of their portfolio | 29.7k $229.6k | New |
| Graham Capital Management, L.P. 0.01% of their portfolio | 28.5k $220.6k | Added +10.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 27.2k $210.2k | Unchanged |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 27.1k $209.7k | Reduced -13.9k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 26.4k $204.3k | Reduced -9.8k |
| Verition Fund Management LLC 0.00% of their portfolio | 25.9k $200.0k | Reduced -15.3k |
| HARBOR CAPITAL ADVISORS, INC. 0.01% of their portfolio | 25.6k $198.0k | Reduced -10.5k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 25.4k $197.6k | Added +8.3k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 24.8k $191.4k | Unchanged |
| SHERBROOKE PARK ADVISERS LLC 0.06% of their portfolio | 24.3k $188.1k | Reduced -5.4k |
| Aristides Capital LLC 0.06% of their portfolio | 24.2k $187.1k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 23.9k $185.0k | Added +2.0k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 22.9k $176.9k | Reduced -3.5k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 19.5k $150.5k | Added +4.1k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 18.3k $141.1k | Added +1.4k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.6k $135.7k | Reduced -373 |