REGENXBIO INC RGNX
COM · Common Stock · CUSIP 75901B107 · ISIN US75901B1070
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersRockville, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($937.9k this quarter). Holder counts are more reliable. Shares outstanding: 43.3m as of 2022-10-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $22.68. Options: 7 managers hold calls ($1.8m notional), 7 hold puts ($1.5m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 183 |
| Q4 2022 | 182 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $2.8m | $2.3m | 0.81 |
| Q4 2022 | $1.8m | $1.5m | 0.83 |
Biggest buyers
| CITADEL ADVISORS LLC | Added | +563.3k |
| Woodline Partners LP | New | +520.6k |
| Invesco Ltd. | Added | +187.5k |
| BlackRock Inc. | Added | +135.1k |
| DIMENSIONAL FUND ADVISORS LP | Added | +105.5k |
| FIRST TRUST ADVISORS LP | New | +98.8k |
| STATE STREET CORP | Added | +96.1k |
| UBS Group AG | Added | +74.2k |
| AMERICAN CENTURY COMPANIES INC | Added | +69.2k |
| Lombard Odier Asset Management (Switzerland) SA | New | +64.2k |
Biggest sellers
| FIRST MANHATTAN CO. LLC. | Reduced | -268.6k |
| JPMORGAN CHASE & CO | Reduced | -260.2k |
| Sofinnova Investments, Inc. | Sold out | -214.0k |
| Sonic Fund II, L.P. | Sold out | -193.1k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Sold out | -110.1k |
| Vident Investment Advisory, LLC | Sold out | -75.3k |
| Ensign Peak Advisors, Inc | Sold out | -72.6k |
| Aquilo Capital Management, LLC | Reduced | -70.0k |
| Atom Investors LP | Sold out | -62.5k |
| Granite Point Capital Management, L.P. | Sold out | -60.0k |
Biggest calls
| JANE STREET GROUP, LLC | Reduced | $748.4k33.0k shares |
| Caption Management, LLC | Reduced | $612.4k27.0k shares |
| CITADEL ADVISORS LLC | Reduced | $192.8k8.5k shares |
| GROUP ONE TRADING LLC | Unchanged | $161.0k7.1k shares |
| SIMPLEX TRADING, LLC | Added | $120.0k5.3k shares |
| Cutler Group LLC / CA | Reduced | $7.0k3.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| JANE STREET GROUP, LLC | Added | $684.9k30.2k shares |
| Caption Management, LLC | Reduced | $612.4k27.0k shares |
| CITADEL ADVISORS LLC | New | $95.3k4.2k shares |
| GROUP ONE TRADING LLC | Reduced | $68.0k3.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $54.0k2.4k shares |
| Cutler Group LLC / CA | Reduced | $13.0k3.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Redmile Group, LLC 13G · passive investor filed 2025-08-14 | 9.9% |
| BlackRock, Inc. 13G · institution -3.7 pts · filed 2025-04-24 | 7.3% |
| JPMORGAN CHASE & CO 13G · institution +0.9 pts · filed 2026-10-13 | 5.3% |
| STATE STREET CORP 13G · institution +0.9 pts · filed 2026-05-12 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), BlackRock Portfolio Management LLC (4.1%, 2026-01-21; now reported by BlackRock, Inc.)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 2 | $4.0m | — |
| Q1 2022 | 0 | — | 1 | $53.9k | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 1 | $913.7k | — |
| Q4 2022 | 0 | — | 0 | — | — |
None reported in Q4 2022.
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.00% of their portfolio | 6.7m $151.6m | Added +135.1k |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.3m $96.9m | Added +5.0k |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 3.8m $86.1m | Reduced -260.2k |
| STATE STREET CORP 0.00% of their portfolio | 2.7m $61.6m | Added +96.1k |
| Redmile Group, LLC 1.78% of their portfolio | 1.9m $43.4m | Reduced -3.7k |
| RTW INVESTMENTS, LP 0.85% of their portfolio | 1.8m $41.9m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.4m $30.8m | Added +105.5k |
| Aquilo Capital Management, LLC 9.06% of their portfolio | 897.7k $20.4m | Reduced -70.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 733.2k $16.6m | Added +25.7k |
| MPM BIOIMPACT LLC 3.66% of their portfolio | 621.4k $14.1m | Added +2.3k |
| Invesco Ltd. 0.00% of their portfolio | 605.9k $13.7m | Added +187.5k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 605.8k $13.7m | Added +563.3k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 596.5k $13.5m | Reduced -34.7k |
| Woodline Partners LP 0.16% of their portfolio | 520.6k $11.8m | New |
| FIRST MANHATTAN CO. LLC. 0.04% of their portfolio | 437.1k $9.9m | Reduced -268.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 428.9k $9.7m | Reduced -59.2k |
| WS MANAGEMENT LLLP 1.38% of their portfolio | 397.0k $9.0m | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 383.9k $8.7m | Added +69.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 359.0k $8.1m | Added +18.9k |
| NORGES BANK 0.00% of their portfolio | 326.6k $7.4m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 310.0k $7.0m | Reduced -38.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 287.6k $6.5m | Added +8.7k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 247.0k $5.6m | Added +3.0k |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 238.9k $5.4m | Added +45.4k |
| ArchPoint Investors 2.41% of their portfolio | 224.3k $5.1m | Reduced -28.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 219.0k $5.0m | Reduced -6.4k |
| Sonic GP LLC 3.29% of their portfolio | 193.1k $4.4m | First filing |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 172.3k $3.9m | Reduced -48.7k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.10% of their portfolio | 169.9k $3.9m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 166.0k $3.8m | Added +31.5k |
| Mirae Asset Global Investments Co., Ltd. 0.01% of their portfolio | 164.5k $3.7m | Reduced -25.2k |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 149.0k $3.4m | Reduced -332 |
| Rafferty Asset Management, LLC 0.03% of their portfolio | 143.2k $3.2m | Added +26.1k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 117.7k $2.7m | Reduced -17.6k |
| Legal & General Group Plc 0.00% of their portfolio | 113.1k $2.6m | Added +2.7k |
| UBS Group AG 0.00% of their portfolio | 112.8k $2.6m | Added +74.2k |
| Hennion & Walsh Asset Management, Inc. 0.15% of their portfolio | 105.3k $2.4m | Added +11.4k |
| Man Group plc 0.01% of their portfolio | 101.0k $2.3m | Added +40.0k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 99.8k $2.3m | Reduced -3.9k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 98.8k $2.2m | New |
| BARCLAYS PLC 0.00% of their portfolio | 96.6k $2.2m | First filing |
| CITIGROUP INC 0.00% of their portfolio | 89.0k $2.0m | Reduced -39.7k |
| Swiss National Bank 0.00% of their portfolio | 88.7k $2.0m | Added +1.8k |
| ROYCE & ASSOCIATES LP 0.02% of their portfolio | 81.6k $1.9m | Added +52.3k |
| Monarch Partners Asset Management LLC 0.48% of their portfolio | 72.1k $1.6m | Reduced -27.5k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 70.6k $1.6m | Added +20.5k |
| Public Sector Pension Investment Board 0.01% of their portfolio | 68.9k $1.6m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 66.3k $1.5m | Added +42 |
| Lombard Odier Asset Management (Switzerland) SA 0.12% of their portfolio | 64.2k $1.5m | New |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 54.1k $1.2m | Added +3.9k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 48.0k $1.1m | Added +548 |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 46.0k $1.0m | Unchanged |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 45.0k $1.0m | Added +25.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 44.5k $1.0m | Added +943 |
| HRT FINANCIAL LP 0.01% of their portfolio | 44.5k $1.0m | Added +36.7k |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 44.1k $1.0m | Reduced -10.8k |
| JENNISON ASSOCIATES LLC 0.00% of their portfolio | 41.4k $937.9k | Reduced -1.0k |
| WINTON GROUP Ltd 0.06% of their portfolio | 40.3k $914.4k | Added +3.3k |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.01% of their portfolio | 40.3k $914.0k | Added +6.0k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 38.6k $876.0k | Reduced -21.4k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 37.6k $851.0k | Unchanged |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 37.1k $840.4k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 36.9k $836.9k | Added +9.5k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 35.0k $793.4k | Reduced -2.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 34.5k $782.4k | Reduced -2.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 34.3k $777.8k | Added +6.5k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 34.3k $777.0k | Reduced -2.7k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 33.2k $753.3k | Added +6.4k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 33.2k $751.9k | Added +21.4k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 33.1k $750.6k | Reduced -8.5k |
| FMR LLC 0.00% of their portfolio | 31.8k $721.0k | Added +125 |
| MONEY CONCEPTS CAPITAL CORP 0.03% of their portfolio | 29.9k $678.8k | Reduced -133 |
| STRS OHIO 0.00% of their portfolio | 29.9k $678.0k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 29.5k $669.0k | Reduced -20.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 29.5k $668.7k | Added +4.6k |
| ALPS ADVISORS INC 0.01% of their portfolio | 29.3k $665.5k | Added +5.7k |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 29.0k $658.4k | Reduced -4.8k |
| LIBERTY ONE INVESTMENT MANAGEMENT, LLC 0.09% of their portfolio | 28.9k $654.4k | Reduced -564 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 28.6k $651.4k | Reduced -6.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 28.4k $645.1k | Reduced -15 |
| TEXAS PERMANENT SCHOOL FUND CORP 0.01% of their portfolio | 27.5k $625.0k | Added +493 |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 27.1k $615.1k | Added +16.5k |
| State of Tennessee, Department of Treasury 0.00% of their portfolio | 26.7k $605.0k | Added +301 |
| HARBOR CAPITAL ADVISORS, INC. 0.59% of their portfolio | 26.7k $605.2k | Reduced -574 |
| SummerHaven Investment Management, LLC 0.36% of their portfolio | 26.7k $604.5k | Added +519 |
| ESSEX INVESTMENT MANAGEMENT CO LLC 0.09% of their portfolio | 26.5k $601.0k | New |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 26.2k $594.0k | Added +188 |
| YOUSIF CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 25.6k $580.9k | Reduced -3.4k |
| Sigma Planning Corp 0.02% of their portfolio | 22.7k $514.2k | Reduced -107 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 22.3k $506.4k | Reduced -935 |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 22.2k $504.0k | Added +12.5k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 21.9k $494.0k | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 21.8k $495.0k | Added +4.8k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 21.7k $491.1k | Reduced -161 |
| COMERICA BANK 0.00% of their portfolio | 20.6k $484.0k | Reduced -6.5k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 20.0k $453.1k | New |
| Louisiana State Employees Retirement System 0.01% of their portfolio | 17.9k $406.0k | Reduced -100 |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 17.5k $397.4k | Reduced -15.2k |
| AMALGAMATED BANK 0.00% of their portfolio | 17.3k $392.0k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 17.3k $392.4k | Reduced -7.8k |