REGENERON PHARMACEUTICALS REGN
COM · Common Stock · CUSIP 75886F107 · ISIN US75886F1075
American pharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersTarrytown, NY
- Founded1988
- Websiteregeneron.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($363.1m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $770.86. Options: 39 managers hold calls ($1.0bn notional), 34 hold puts ($1.1bn).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 1,080 |
| Q4 2022 | 1,159 |
| Q1 2023 | 1,195 |
| Q2 2023 | 1,168 |
| Q3 2023 | 1,182 |
| Q4 2023 | 1,275 |
| Q1 2024 | 1,313 |
| Q2 2024 | 1,335 |
| Q3 2024 | 1,393 |
| Q4 2024 | 1,320 |
| Q1 2025 | 1,292 |
| Q2 2025 | 1,202 |
| Q3 2025 | 1,243 |
| Q4 2025 | 1,387 |
| Q1 2026 | 1,400 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 656 | 514 |
| Q3 2024 | 662 | 533 |
| Q4 2024 | 561 | 709 |
| Q1 2025 | 650 | 603 |
| Q2 2025 | 563 | 683 |
| Q3 2025 | 646 | 527 |
| Q4 2025 | 686 | 562 |
| Q1 2026 | 683 | 565 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $1.2bn | $1.1bn | 0.89 |
| Q3 2025 | $1.5bn | $1.1bn | 0.70 |
| Q4 2025 | $2.2bn | $1.2bn | 0.57 |
| Q1 2026 | $1.0bn | $1.1bn | 1.06 |
Biggest buyers
| WELLINGTON MANAGEMENT GROUP LLP | Added | +1.2m |
| TWO SIGMA INVESTMENTS, LP | Added | +531.1k |
| JPMORGAN CHASE & CO | Added | +371.6k |
| Bellevue Group AG | Added | +264.7k |
| AQR CAPITAL MANAGEMENT LLC | Added | +235.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +227.7k |
| Amundi | Added | +217.9k |
| BlackRock, Inc. | Added | +206.5k |
| GOLDMAN SACHS GROUP INC | Added | +203.2k |
| FRANKLIN RESOURCES INC | Added | +162.1k |
Biggest sellers
| FMR LLC | Reduced | -801.4k |
| TWO SIGMA ADVISERS, LP | Sold out | -604.5k |
| MARSHALL WACE, LLP | Reduced | -478.2k |
| Holocene Advisors, LP | Sold out | -460.7k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -317.0k |
| HSBC HOLDINGS PLC | Reduced | -314.3k |
| ACADIAN ASSET MANAGEMENT LLC | Reduced | -294.6k |
| Point72 Asset Management, L.P. | Reduced | -260.4k |
| FIL Ltd | Reduced | -219.7k |
| 1832 Asset Management L.P. | Reduced | -214.9k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $259.4m335.7k shares |
| CITADEL ADVISORS LLC | Reduced | $165.1m213.7k shares |
| GOLDMAN SACHS GROUP INC | Reduced | $144.9m187.6k shares |
| JANE STREET GROUP, LLC | Reduced | $124.8m161.5k shares |
| IMC-Chicago, LLC | Reduced | $110.2m142.6k shares |
| Bronte Capital Management Pty Ltd. | Added | $53.0m68.6k shares |
| Nantahala Capital Management, LLC | Unchanged | $30.9m40.0k shares |
| MILLENNIUM MANAGEMENT LLC | Reduced | $21.8m28.2k shares |
| HRT FINANCIAL LP | Added | $14.8m19.1k shares |
| ROYAL BANK OF CANADA | New | $13.6m17.6k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $469.6m607.8k shares |
| CITADEL ADVISORS LLC | Reduced | $133.2m172.4k shares |
| Point72 Asset Management, L.P. | Added | $111.1m143.8k shares |
| JANE STREET GROUP, LLC | Reduced | $87.8m113.7k shares |
| IMC-Chicago, LLC | Reduced | $76.2m98.6k shares |
| GROUP ONE TRADING LLC | Added | $37.3m48.3k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $31.9m41.3k shares |
| LMR Partners LLP | Added | $30.1m39.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $16.6m21.5k shares |
| GOLDMAN SACHS GROUP INC | Reduced | $12.7m16.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 7.4% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 7 | $189.5m | $189.5m |
| Q3 2024 | 0 | — | 9 | $40.6m | $20.6m |
| Q4 2024 | 0 | — | 2 | $2.0m | $2.0m |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 3 | $5.1m | $570.0k |
| Q1 2026 | 0 | — | 4 | $4.2m | $4.2m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-03-02 | RYAN ARTHUR F Director | Sold plan | $78.5k100 shares |
| 2026-02-19 | Zoghbi Huda Y Director | Sold plan | $1.3m1.6k shares |
| 2026-02-09 | Pitofsky Jason SVP Controller | Sold plan | $1.6m2.0k shares |
| 2026-02-09 | RYAN ARTHUR F Director | Sold plan | $77.9k100 shares |
| 2026-01-07 | Bassler Bonnie L Director | Sold plan | $1.2m1.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.12% of their portfolio | 8.9m $6.9bn | Added +206.5k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.13% of their portfolio | 6.7m $5.1bn | First filing |
| STATE STREET CORP 0.12% of their portfolio | 4.7m $3.6bn | Added +3.7k |
| Dodge & Cox 1.89% of their portfolio | 4.5m $3.4bn | Reduced -138.1k |
| JPMORGAN CHASE & CO 0.22% of their portfolio | 4.3m $3.2bn | Added +371.6k |
| Invesco Ltd. 0.29% of their portfolio | 3.9m $3.0bn | Reduced -6.4k |
| FRANKLIN RESOURCES INC 0.52% of their portfolio | 2.7m $2.1bn | Added +162.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.12% of their portfolio | 2.6m $2.0bn | Added +88.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.19% of their portfolio | 2.2m $1.7bn | Added +227.7k |
| Nuveen, LLC 0.43% of their portfolio | 2.1m $1.6bn | Added +54.5k |
| LOOMIS SAYLES & CO L P 1.99% of their portfolio | 1.9m $1.5bn | Reduced -22.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.27% of their portfolio | 1.8m $1.4bn | Added +1.2m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.07% of their portfolio | 1.7m $1.3bn | First filing |
| FMR LLC 0.06% of their portfolio | 1.5m $1.2bn | Reduced -801.4k |
| Capital World Investors 0.15% of their portfolio | 1.4m $1.1bn | Added +21.0k |
| MORGAN STANLEY 0.06% of their portfolio | 1.3m $1.0bn | Reduced -70.0k |
| GOLDMAN SACHS GROUP INC 0.13% of their portfolio | 1.3m $1.0bn | Added +203.2k |
| AQR CAPITAL MANAGEMENT LLC 0.43% of their portfolio | 1.2m $946.0m | Added +235.3k |
| BANK OF AMERICA CORP /DE/ 0.07% of their portfolio | 1.2m $919.1m | Added +32.2k |
| Amundi 0.21% of their portfolio | 1.0m $780.2m | Added +217.9k |
| NORTHERN TRUST CORP 0.10% of their portfolio | 941.9k $727.8m | Reduced -3.0k |
| TWO SIGMA INVESTMENTS, LP 0.52% of their portfolio | 812.2k $627.6m | Added +531.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.09% of their portfolio | 804.5k $621.6m | Added +26.5k |
| Bank of New York Mellon Corp 0.11% of their portfolio | 765.4k $591.4m | Added +1.2k |
| Legal & General Group Plc 0.13% of their portfolio | 732.1k $565.6m | Reduced -11.0k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.12% of their portfolio | 723.6k $559.1m | Reduced -21.6k |
| DEUTSCHE BANK AG\ 0.16% of their portfolio | 625.4k $483.2m | Reduced -138.5k |
| VANGUARD FIDUCIARY TRUST CO 0.11% of their portfolio | 569.9k $440.4m | First filing |
| AMERICAN CENTURY COMPANIES INC 0.22% of their portfolio | 562.1k $434.3m | Added +10.6k |
| DIMENSIONAL FUND ADVISORS LP 0.08% of their portfolio | 513.1k $396.3m | Added +13.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.23% of their portfolio | 448.4k $346.4m | Added +7.5k |
| NEUBERGER BERMAN GROUP LLC 0.25% of their portfolio | 427.1k $330.1m | Added +5.0k |
| ALLIANCEBERNSTEIN L.P. 0.11% of their portfolio | 426.9k $329.5m | Reduced -51.5k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.27% of their portfolio | 408.9k $316.0m | Reduced -12.3k |
| National Pension Service 0.22% of their portfolio | 371.6k $287.1m | Added +10.6k |
| Pacer Advisors, Inc. 0.79% of their portfolio | 358.6k $277.1m | Reduced -39.0k |
| ROYAL BANK OF CANADA 0.05% of their portfolio | 351.2k $271.3m | Added +6.0k |
| TD Asset Management Inc 0.22% of their portfolio | 350.9k $271.1m | Reduced -46.6k |
| VOYA INVESTMENT MANAGEMENT LLC 0.28% of their portfolio | 349.9k $270.1m | Added +55.9k |
| Robeco Institutional Asset Management B.V. 0.38% of their portfolio | 348.8k $269.5m | Added +86.9k |
| FIRST TRUST ADVISORS LP 0.19% of their portfolio | 346.9k $268.0m | Added +141.1k |
| Pictet Asset Management Holding SA 0.27% of their portfolio | 337.3k $258.4m | Reduced -30.6k |
| Caisse de depot et placement du Quebec 0.41% of their portfolio | 329.0k $254.2m | Reduced -13.3k |
| HSBC HOLDINGS PLC 0.15% of their portfolio | 323.3k $249.7m | Reduced -314.3k |
| AMERIPRISE FINANCIAL INC 0.06% of their portfolio | 319.7k $247.1m | Added +27.8k |
| Man Group plc 0.50% of their portfolio | 315.2k $243.5m | Added +97.1k |
| BARCLAYS PLC 0.09% of their portfolio | 313.1k $241.9m | Added +1.9k |
| FIL Ltd 0.19% of their portfolio | 309.5k $239.1m | Reduced -219.7k |
| Swiss National Bank 0.13% of their portfolio | 303.1k $234.2m | Added +17.7k |
| Allianz Asset Management GmbH 0.27% of their portfolio | 301.2k $232.7m | Added +132.6k |
| UBS Group AG 0.04% of their portfolio | 300.0k $231.8m | Added +28.8k |
| Bellevue Group AG 5.12% of their portfolio | 278.7k $215.3m | Added +264.7k |
| Sumitomo Mitsui Trust Group, Inc. 0.14% of their portfolio | 273.7k $211.4m | Reduced -11.4k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.24% of their portfolio | 273.1k $211.0m | Added +26.6k |
| FEDERATED HERMES, INC. 0.32% of their portfolio | 254.9k $197.0m | Added +8.3k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.12% of their portfolio | 240.6k $185.9m | Added +15.7k |
| Epoch Investment Partners, Inc. 1.12% of their portfolio | 238.7k $184.4m | Reduced -42.6k |
| Vanguard Global Advisers, LLC 0.09% of their portfolio | 228.5k $176.5m | First filing |
| Russell Investments Group, Ltd. 0.19% of their portfolio | 228.1k $175.7m | Added +7.0k |
| California Public Employees Retirement System 0.10% of their portfolio | 218.8k $169.0m | Added +17.7k |
| Swedbank AB 0.18% of their portfolio | 215.6k $166.6m | Reduced -12.2k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.70% of their portfolio | 214.2k $165.5m | Reduced -50.8k |
| DekaBank Deutsche Girozentrale 0.27% of their portfolio | 211.2k $160.9m | Unchanged |
| JANUS HENDERSON GROUP PLC 0.08% of their portfolio | 209.2k $161.6m | Added +3.6k |
| Assenagon Asset Management S.A. 0.26% of their portfolio | 207.8k $160.5m | Reduced -25.4k |
| MCDONALD CAPITAL INVESTORS INC/CA 10.88% of their portfolio | 205.9k $159.1m | Reduced -2.4k |
| Chevy Chase Trust Holdings, LLC 0.46% of their portfolio | 205.8k $159.0m | Added +5.1k |
| LSV ASSET MANAGEMENT 0.33% of their portfolio | 196.3k $151.7m | Added +29.8k |
| Polar Capital Holdings Plc 0.65% of their portfolio | 192.5k $148.8m | Reduced -12.4k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.09% of their portfolio | 187.6k $144.9m | Added +19.2k |
| Candriam S.C.A. 0.75% of their portfolio | 186.4k $144.0m | Reduced -18.9k |
| CITIGROUP INC 0.09% of their portfolio | 184.7k $142.7m | Reduced -60.6k |
| VANGUARD ASSET MANAGEMENT, Ltd 0.12% of their portfolio | 176.3k $136.2m | First filing |
| Bronte Capital Management Pty Ltd. 14.39% of their portfolio | 172.8k $133.5m | Reduced -4.0k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.07% of their portfolio | 171.6k $132.6m | Reduced -23.1k |
| RAYMOND JAMES FINANCIAL INC 0.04% of their portfolio | 165.5k $127.9m | Added +15.9k |
| Squarepoint Ops LLC 0.27% of their portfolio | 162.8k $125.8m | Added +160.1k |
| SG Americas Securities, LLC 0.13% of their portfolio | 158.3k $122.3m | Added +27.2k |
| RHUMBLINE ADVISERS 0.10% of their portfolio | 157.8k $121.9m | Reduced -3.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.13% of their portfolio | 154.2k $119.1m | Reduced -4.5k |
| ProShare Advisors LLC 0.17% of their portfolio | 152.4k $117.7m | Reduced -31.9k |
| ACADIAN ASSET MANAGEMENT LLC 0.17% of their portfolio | 151.2k $116.8m | Reduced -294.6k |
| Sound Shore Management Inc /CT/ 3.91% of their portfolio | 151.0k $116.6m | Reduced -24.9k |
| WELLS FARGO & COMPANY/MN 0.02% of their portfolio | 142.0k $109.7m | Added +2.0k |
| PRUDENTIAL FINANCIAL INC 0.13% of their portfolio | 140.5k $108.5m | Added +53.3k |
| SOUTHEASTERN ASSET MANAGEMENT INC/TN/ 4.97% of their portfolio | 130.7k $101.0m | Reduced -35.1k |
| NATIONAL BANK OF CANADA /FI/ 0.10% of their portfolio | 130.0k $100.4m | Added +10.2k |
| VICTORY CAPITAL MANAGEMENT INC 0.06% of their portfolio | 129.1k $99.7m | Added +17.1k |
| Retirement Systems of Alabama 0.33% of their portfolio | 128.3k $99.1m | Reduced -32 |
| NATIXIS ADVISORS, LLC 0.14% of their portfolio | 125.7k $97.1m | Added +3.1k |
| Handelsbanken Fonder AB 0.32% of their portfolio | 125.0k $96.6m | Added +24.3k |
| Mariner, LLC 0.11% of their portfolio | 124.0k $95.7m | Added +28.7k |
| Aberdeen Group plc 0.15% of their portfolio | 121.3k $93.8m | Reduced -40.4k |
| PRINCIPAL FINANCIAL GROUP INC 0.05% of their portfolio | 120.4k $93.0m | Added +800 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.13% of their portfolio | 117.4k $90.7m | Unchanged |
| Carmignac Gestion 1.38% of their portfolio | 116.6k $90.0m | Added +66.6k |
| JENNISON ASSOCIATES LLC 0.06% of their portfolio | 115.2k $89.0m | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.15% of their portfolio | 109.7k $84.9m | Added +849 |
| ENVESTNET ASSET MANAGEMENT INC 0.02% of their portfolio | 109.2k $84.3m | Added +20.2k |
| DANSKE BANK A/S 0.20% of their portfolio | 107.2k $82.8m | Added +7.9k |